陳大全

陳大全

陳大全,教授、博士研究生導師、泰山學者青年專家。

基本介紹

  • 中文名:陳大全 
  • 國籍:中國
  • 民族:漢
  • 畢業院校:中國藥科大學
  • 職稱/職務:博士生導師
人物經歷,研究方向,主要貢獻,

人物經歷

2000.09-2004.06 陝西中醫藥大學中藥製藥本科 獲學士學位
2004.09-2007.06 陝西中醫藥大學中藥學(藥劑)碩士研究生 獲碩士學位
2007.09-2010.06 中國藥科大學 藥劑學博士研究生獲博士學位
2014.12-2016.12 北京大學 博士後
2015.09-2016.09 哈佛大學 博士後
2010.09-2013.12 煙臺大學藥學院 藥劑學講師
2014.01-2018.05 煙臺大學藥學院 藥劑學副教授 碩導(2014)、博導(2017)
2018.06- 煙臺大學藥學院 藥劑學教授 碩導、博導。

研究方向

研究方向:1.新型藥用高分子材料與智慧型靶向納米藥物研究;2. 藥物與中藥新製劑、新劑型研究開發;3.海洋藥物、材料及藥代動力學研究;3. 保健食品、化妝品及獸藥製劑產品開發研究;4.現代生物農藥及肥料開發研究
主要研究內容:微粒和毫微粒給藥系統;聚合物膠束及脂質體;生物大分子和高分子材料的設計與可控合成,以及各種新型醫藥材料在藥物傳遞、腫瘤診斷與治療、幹細胞治療和光動力學治療等領域的套用。包括智慧型pH敏感膠束、脂質體、微球、納米粒等;基於中藥組分和藥用新載體的現代中藥研究及藥物動力學評價;新型藥用輔料的研究;難溶性藥物的速釋、緩釋製劑的研究,中藥現代化製劑研究,海洋藥物及材料、保健食品、獸藥製劑、生物農藥等。

主要貢獻

1.DaquanChen*,Wanjun Liu,Qingmeng Pi,Jingzhou Yang,Yu Shrike Zhang, Preparation of injectable GelMA nanoparticles-based 3D printed wound healing fillerJournalofControlledRelease,2017,259,e23. (IF:7.877)1區 Top期刊
2.Daquan Chen*,Xue Dong,Mengjiao Qi,Xiaoyan Song,Jingfang Sun,Dual pH/redox responsive and CD44 receptor targeting hybrid nano-chrysalis based on new oligosaccharides of hyaluronan conjugates,Carbohydrate Polymers,2017,157:1272~1280. (IF: 5.158)1區 Top期刊
3.Chunjing Guo,Jungang Yin*,Daquan Chen*.Co-encapsulation of curcumin and resveratrol into novel nutraceutical hyalurosomes nano-food delivery system based on oligo-hyaluronic acid-curcumin polymer. CarbohydratePolymers.2018,181:1033-1037.(IF:5.158) 1區 Top期刊
4.Daquan Chen, Jingfang Sun, In vitro and in vivo evaluation of PEG-conjugated ketal-based chitosan micelles as the pH-sensitive carriers,Polymer Chemistry,2015,6(6):998~1004.(IF:4.927)1區 Top期刊
5.Mengjiao Qi,Xiaoyan Song,Xue Dong,Jingfang Sun,DaquanChen*, Oligosaccharides of hyaluronan conjugates-based dual pH-responsive nano-pupa for cancer stem cell targeted combinatorial chemotherapy. Journal of Controlled Release,2017,259,e92.(IF:7.877)1區 Top期刊
6. Kaili Wang , Chunjing Guo, Xue Dong, Yueming Yu , Bingjie Wang, Wanhui Liu, Daquan Chen*.In vivo evaluation of Reduction-ResponsiveAlendronate-Hyaluronan-Curcumin Polymer-Drug Conjugates for Targeted Therapy of Bone Metastatic Breast Cancer.Molecular Pharmaceutics, 2018, 15(7):2764-2769. (IF:4.556) 2區
7. Yueming Yu, Shaohua Zou, Kaili Wang, Rongcai Liang, Xinxin Fan, Bingjie Wang,Mengna Liu, Lei Fang, Wanhui Liu, Zimei Wu, Daquan Chen*.Synthesis, Characterization and In Vitro Evaluation of Dual pH/Redox Sensitive Marine Laminarin-Based Nanomedicine Carrier Biomaterial for Cancer Therapy.Journal ofBiomedicalNanotechnology. 2018, 14(9):1568-1577.(IF:5.068 ) 2區
8. Mengjiao Qi, Shaohua Zou, Chunjing Guo, Kaili Wang, Yueming Yu , Feng Zhao, Huaying Fan, Zimei Wu, Wanhui Liu, Daquan Chen*. Enhanced In Vitro and In Vivo Anticancer Properties by Using a Nanocarrier for Co-Delivery of Antitumor Polypeptide and Curcumin.Journal of Biomedical Nanotechnology.2018, 14(1):139-149.(IF:5.068 ) 2區
9. Kaili Wang, Mengjiao Qi, Chunjing Guo, Yueming Yu, Bingjie Wang, Lai Fang, Mengna Liu, Zhen Wang, Xinxin Fan, Daquan Chen*.Novel Dual Mitochondrial and CD44 Receptor Targeting Nanoparticles for Redox Stimuli-Triggered Release.Nanoscale ResearchLetter. 2018,13(1):32.(IF:3.125) 2區
10.Daquan Chen,Shengnan Lian,Jingfang Sun,Zongliang Liu,Feng Zhao,Yongtao Jiang,Mingming Gao,Kaoxiang Sun ,Wanhui Liu ,Fenghua Fu,Design of novel multifunctional targeting nano-carrier drug delivery system based on CD44 receptor and tumor microenvironment pH condition,Drug Delivery,2016,23(3):808~813.(IF:3.095)2區

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