陳佳是上海科技大學生命科學與技術學院助理教授,研究領域為DNA修復引發突變及癌症發生的分子機制。
基本介紹
- 中文名:陳佳
- 國籍:中國
- 民族:漢
- 出生地:江西
- 職業:科學家
- 畢業院校:中科院上海生物化學與細胞生物學研究所
- 研究方向:DNA修復及癌症發生
個人簡介
研究工作
代表論文
Featured in Insight Article by Wilson SH. eLife, 2014, 3: e03068
2. Hu GJ*, Chen J*, Zhao XN*, Xu JJ, Guo DQ, Lu M, Zhu M, Xiong Y, Li Q, Chang CC, Song BL, Chang TY, Li BL. Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene. Cell Res, 2013, 23: 1007-1024 (*co-first author)
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Featured in Research Highlight Article by Preußer C, Bindereif A. Cell Res, 2013, 23: 1071-1072
3. Lei L, Xiong Y, Chen J, Yang JB, Wang Y, Yang XY, Chang CC, Song BL, Chang TY, Li BL. TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation. J Lipid Res, 2009, 50: 1057-1067
4. Zhao X*, Chen J*, Lei L, Hu G, Xiong Y, Xu J, Li Q, Yang X, Chang CC, Song B, Chang T, Li B. The optional long 5'-untranslated region of human ACAT1 mRNAs impairs the production of ACAT1 protein by promoting its mRNA decay. Acta Biochim Biophys Sin, 2009, 41: 30-41 (*co-first author)
5. Chen J*, Zhao XN*, Yang L, Hu GJ, Lu M, Xiong Y, Yang XY, Chang CC, Song BL, Chang TY, Li BL. RNA secondary structures located in the interchromosomal region of human ACAT1 chimeric mRNA are required to produce the 56-kDa isoform. Cell Res, 2008, 18: 921-936 (*co-first author)
6. Yang L, Lee O, Chen J, Chen J, Chang CC, Zhou P, Wang ZZ, Ma HH, Sha HF, Feng JX, Wang Y, Yang XY, Wang L, Dong R, Ornvold K, Li BL, Chang TY. Human acyl-coenzyme A:cholesterol acyltransferase 1(Acat1) sequences located in two different chromosomes (7 and 1) are required to produce a novel ACAT1 isoenzyme with additional sequence at the N-terminal. J Biol Chem, 2004, 279: 46253-46262
7. Li BL, Chang TY, Chen J, Chang CC, Zhao XN. Human ACAT1 gene expression and its involvement in the development of atherosclerosis. Future Cardiol, 2006, 2: 93-99 (Review)
8. Yang L, Yang JB, Chen J, Yu GY, Zhou P, Lei L, Wang ZZ, Cy Chang C, Yang XY, Chang TY, Li BL. Enhancement of human ACAT1 gene expression to promote the macrophage-derived foam cell formation by dexamethasone. Cell Res, 2004, 14: 315-323
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