邱立鵬，女，博士，江蘇大學生命科學研究院副研究員，碩士生導師。
基本介紹
- 中文名：邱立鵬
- 學位/學歷：博士
- 職業：教師
- 專業方向：非編碼RNA在肝癌和肺癌中的功能及機制研究
- 任職院校：江蘇大學生命科學研究院
個人經歷,研究方向,學習成果,
個人經歷
學習經歷:
2007.08—2011.07 中國科學院微生物研究所，生物化學與分子生物學專業，理學博士
2001.08—2004.07 瀋陽藥科大學製藥工程學院，微生物與生化藥學專業，理學碩士
2001-2002 瀋陽藥科大學，完成課程學習
2002-2004 浙江大學藥學院，完成碩士論文
1997.08—2001.07 瀋陽藥科大學製藥工程學院，微生物製藥專業，工學學士
工作經歷：
2011.07—現在 江蘇大學生命科學研究院，助理研究員/副研究員
2013.12—2016.09 美國約翰霍普金斯大學醫學院，訪問學者/博士後
2004.07—2007.07 常州大學化學工程學院製藥工程教研室，助教
研究方向
非編碼RNA在肝癌和肺癌中的功能及機制研究
學習成果
主持項目
1. 國家自然科學基金青年基金，2015.01-2017.12，結題
2. 江蘇省自然科學基金，2013.07-2016.06，結題
3. 中國博士後科學基金面上項目，2012.09-2014.09，結題
4. 江蘇大學高級專業人才科研啟動基金，2012.01-2014.12，在研
5. 江蘇大學青年骨幹教師培養工程資助， 2015.01-2018.12，在研
參加項目
1. 國家自然科學基金青年基金，2015.01-2017.12，結題，主要參與人（3/5）
2. 國家自然科學基金，2010.01-2012.12，結題
3. 國家973計畫子課題，2007.01-2011.12，結題
4. 國家863計畫，2007.01-2010.12，結題
【科研成果】
已發表SCI收錄論文二十餘篇，總計引用次數550餘次。
1. Lipeng Qiu, Han Xu, Mengchen Ji, DongshengShang, Ziwen Lu, Yihang Wu, Zhigang Tu, Hanqing Liu*. Circular RNAs inhepatocellular carcinoma: biomarkers, functions and mechanisms. Life Sci.
2. Lipeng Qiu*, Tao Wang, Qi Ge, HanXu, Yihang Wu, Qi Tang, Keping Chen*. Circular RNA signature inhepatocellular carcinoma. J Cancer.
3. LipengQiu#, Yan Zhang#, Danh C. Do, Xia Ke, Simin Zhang, KristinLambert, Shruthi Kumar, Chengping Hu, Yufeng Zhou, Faoud T. Ishmael* andPeisong Gao*. miR-155 modulates cockroach allergen- and oxidativestress-induced cyclooxygenase-2 in asthma. J Immunol.
4. LipengQiu*, Tao Wang, Qi Tang, Guohui Li, Peng Wu and Keping Chen*.Long non-coding RNAs: regulators of viral infection and the interferonantiviral response. Front Microbiol.
5. LipengQiu*, Yihang Wu, Xiaofeng Yu, Qi Tang, Liang Chen, KepingChen*. The emerging role of circular RNAs in hepatocellular carcinoma. JCancer.
6. LipengQiu*, Tao Wang, Xiuquan Xu, Yihang Wu, Qi Tang and KepingChen*. Long non-coding RNAs in hepatitis B virus-related hepatocellularcarcinoma: regulation, functions and underlying mechanisms. Int.
7. Lipeng Qiu, QiTang, Guohui Li, Keping Chen*.Long non-coding RNAs as biomarkers andtherapeutic targets: Recent insights into hepatocellular carcinoma. LifeSci.
8. Li-PengQiu, Liang Chen, Ke-Ping Chen*. Antihepatitis B therapy: areview of current medications and novel small molecule inhibitors. FundamClin Pharmaco
9. Li-PengQiu, Ke-Ping Chen*. Anti-HBV agents derived from botanical origin. Fitoterapia.
10. LipengQiu, Hongxia Fan, Wensong Jin, Bao Zhao, Yanzhong Wang, YingJu, Lizhao Chen, Yu Chen, Zhongping Duan and Songdong Meng*. MiR-122-induced down-regulation of HO-1 negatively affects miR-122-mediated suppression of HBV. Biochem Biophys Res Commun.
11. Saifeng Wang#, LipengQiu#, Xiaoli Yan, Wensong Jin, Yanzhong Wang, Lizhao Chen, Erjie Wu, XinYe, George F Gao, Fusheng Wang, Yu Chen, Zhongping Duan*, Songdong Meng*. Loss of microRNA 122 expression in patients with hepatitis B enhanceshepatitis B virus replication through cyclin G1-modulated P53 activity. Hepatology.
12. SaifengWang#, Lipeng Qiu#, Guangze Liu, Yang Li, Xiaojun Zhang, Wensong Jin, George F Gao, Xianping Kong*, Songdong Meng*. Heat shock protein gp96enhances humoral and T cell responses, decreases Treg frequency and potentiates the anti-HBV activity in BALB/c and transgenic mice. Vaccine.
13. LipengQiu*, Qi Tang, Guohui Li. Heme oxygenase 1 attenuates cockroachallergen-induced airway inflammation. J Allergy Clin Immunol,Supp, AB117. Annual meeting of AAAAI (the American Academy of Allergy, Asthma & Immunology). Orlando. March,
14. LipengQiu, Yufeng Zhou, Yilin Zhao, Danh Do, Heng Wang, Changjun Li, Xiaopeng Liu, Xu Cao, Mei Wan, Peisong Gao*. microRNA-155 regulates cockroach allergen induced cyclooxygenase-2 expression in airway epithelium. JAllergy Clin Immunol. Supp, AB175. Annual meeting of AAAAI. Los angeles. March, 201
15. Zhicong Zhao, Dongsheng Shang, Lipeng Qiu, Chang Guo, Yanyan Li, Hanqing Liu, Guoyue Yuan*, Zhigang Tu*.4,5-diphenyl-2-methyl picolinate induces cellular senescence by accumulating DNA damage and activating associated signaling pathways in gastric cancer. Life Sci.
16. Shengjie Chen, TianyiGu, Ziwen Lu, Lipeng Qiu, Guoliang Xiao, Xiaozhong Zhu, Feng Li, Hui Yu, Gang Li,Hanqing Liu*.Roles of MYC-targeting long non-coding RNA MINCR in cell cycle regulation and apoptosis in non-small cell lung Cancer. Resp Res.
17. Qi Tang, Lipeng Qiu, Guohui Li*. Baculovirus-encoded microRNAs: a brief overview and futureprospects. Curr Microbiol.
18. Liang Chen, YanhuaYang, Yiting Wang, Lipeng Qiu, Hengchuan Xia, Aiai Wang, Hailong Liu, Hongfei Shi*, Keping Chen*. Proteomic response of the rat liver in differential swimming modes. Clin Exp Pharmacol P.
19. Huan Zuo, LiangChen, Ming Kong, Yanhua Yang, Peng Lv, Lipeng Qiu, Qiang Wang, Shangshang Ma, Keping Chen*. The toxic effect of sodium fluoride on Spodoptera frugiperda 9 cells and differential proteinanalysis following NaF treatment of cells. Environ Pollut.
20. Huan Zuo, LiangChen, Ming Kong, Lipeng Qiu, Peng Lv, Peng Wu, Yanhua Yang, Keping Chen*. Toxic effects of fluoride on organisms. Life Sci
21. Yufeng Zhou, DanC.Do, Faoud T. Ishmael, Mario Leonardo Squadrito, Ho Man Tang, Ho Lam Tang,Man-Hsun Hsu, Lipeng Qiu, Changjun Li, Yongqing Zhang, Kevin G. Becker, Mei Wan, Shau-Ku Huang*, Peisong Gao*.Mannose receptormodulates macrophage polarization and allergic inflammation through miR-511-3p. J Allergy Clin Immunol,（3）
22. Yi-Hang Wu*, Bing-Yi Zhang, Li-Peng Qiu, Rong-Fa Guan, Zi-Hong Ye, Xiao-Ping Yu. Structure properties and mechanisms of action of naturally originated phenolic acids and their derivatives against human viral infections. CurrMed Chem.
23. Qi Tang, Peng Wu, Zhaoyang Hu, Yanhua Yang, Lipeng Qiu, Hanqing Liu, Shanying Zhu,Zhongjian Guo, Hengchuan Xia, Keping Chen*, Guohui Li*. Evidence for the role of BmNPV Bm65 protein in the repair of ultraviolet-induced DNA damage. JInvertebr Pathol.
24. Guohui Li, Qian Zhou, Lipeng Qiu, Qin Yao, Keping Chen, Qi Tang*, Zhaoyang Hu*. Serine protease Bm-SP142 was differentially expressed in resistant andsusceptible Bombyx mori strains, involving in the defence response to viral infection. PLoS ONE.
25. Feng li, Yi-Dan Mao, Yi-Fan Wang, Aun Raza, Li-Peng Qiu and Xiu-Quan Xu*.Optimization of Untrasonic-Assisted Enzymatic Extraction Conditions for Improving Total Phenolic Content, Antioxidant and Antitumor Activities In Vitro from Trapa quadrispinosa Roxb. Residues. Molecules. 2017, 22(3): 396.(IF=3.098)
26. Yilin Zhao, Xiaoyan Luo, Lipeng Qiu, Danh C. Do, Xia Ke, Eric Zaccone, Bradley J. Undem, Peisong Gao*, Aryl Hydrocarbon receptor in airway epithelium exacerbates cockroach allergen-induced asthma through autophagy, J Allergy Clin Immunol, 2017, 139(2), Supp, AB268. Annual meeting of AAAAI. Atlanta. March,
27. Weiwei Liu, MiChen, Xinghui Li, Bao Zhao, Junwei Hou, Huaguo Zheng, Lipeng Qiu,Zihai Li, Songdong Meng*. Interaction of Toll-Like Receptors with theMolecular Chaperone Gp96 Is Essential for Its Activation of Cytotoxic TLymphocyte Response. PLoS ONE.
28. Yilin Zhao, LipengQiu, Danh Do, Heng Wang, Xiaopeng Liu, Peisong Gao. MicroRNA-203 regulates aryl hydrocarbon receptor in cockroach mediated allergicresponses. J Allergy Clin Immunol. 2016, 137(2), Supp,AB199. Annual meeting of AAAAI. Los angeles. March, 2016. (IF=13.258, 會議論文)
29. Ting Xu#, Yufeng Zhou#, Lipeng Qiu, Danh C. Do, Yilin Zhao, Zhuang Cui, Heng Wang, Xiaopeng Liu, Arjun Saradna, Mei Wan, and Peisong Gao*. Aryl hydrocarbon receptor protects lungs from cockroach allergen-induced inflammation bymodulating mesenchymal stem cells. J Immunol
30. Qi Tang, Zhaoyang Hu, Yanhua Yang, Huiling Wu, Lipeng Qiu, Keping Chen*, Guohui Li*. Overexpression of Bm65 correlates with reduced susceptibility to inactivation by UV light. J Invertebr Pathol.
31. Yu Zhang, Yulin Ren, Yan Wu, Bao Zhao, Lipeng Qiu, Xiaodong Li, Dongping Xu, Jun Liu, George F. Gao*, Songdong Meng*. The L60V variation in HBV core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication. J Virol.
32. Zhen Liu#, Xinghui Li#, Lipeng Qiu, Xiaojun Zhang, Lizhao Chen, Sheng Cao, FushengWang and Songdong Meng*. Treg suppress CTL responses upon immunization with HSP gp96. Eur J Immunol. 20
33. 郜衍周, 范紅霞，邱立鵬*，孟頌東*.IFN-α對gp96的上調降低其抗HBV的效率. 微生物學報.
34. 任玉林，張宇，邱立鵬，張小俊，陳煜，王福生，謝堯，高斌，段鐘平，孟頌東*. 新型HLA-A2限制的B, C型HBV特異性CTL表位的篩選及鑑定. 科學通報.
35. 於榮敏*，邱立鵬，趙昱，孫平華，葉文才，姚新生. 植物生物轉化技術在藥用活性成分生產及新藥開發中的套用. 中國新藥雜誌.
