賈瀟凌

賈瀟凌，女，博士，北京航空航天大學生物與醫學工程學院副教授。

基本介紹

  • 中文名：賈瀟凌
  • 畢業院校：中國科學院力學研究所
  • 學位/學歷：博士
  • 職業：教師
  • 專業方向：生物力學及力生物學
  • 任職院校：北京航空航天大學生物與醫學工程學院
  • 職稱：副教授
研究方向,人物經歷,科研成果,

研究方向

生物力學及力生物學

人物經歷

主要教育、科研簡歷：
  1. 1988–1992山西大學、生物系、生物學專業、學士學位
  2. 1988–1995山西大學、生物系、動物學專業、碩士學位
  3. 1995–2003中國輻射防護研究院組織庫、助理研究員
  4. 2003–2007中國科學院力學研究所、國家微重力實驗室、生物力學專業、博士
  5. 2003–北京航空航天大學、生物與醫學工程學院、講師、副教授

科研成果

近期主要論著
  1. Fengxuan Han,Xiaoling Jia (賈瀟凌), D Dai,et alPerformance of a multilayered small-diameter vascular scaffold dual-loaded with VEGF and PDGF.Biomaterials.2013;34(30):7302-7312(Co-first)
  2. Hong Zhang,Xiaoling Jia (賈瀟凌), Fengxuan Han,et alDual-Delivery of VEGF and PDGF by Double-layered Electrospun Membranes for for Blood Vessel Regeneration.Biomaterials.2013;34(9):2202-2212(Co-first)
  3. Xiaoling Jia (賈瀟凌), Jingyun Yang, Wei Song,et al.Involvement of large conductance Ca-activated Kchannel in laminar shear stress-induced inhibition of vascular smooth muscle cell proliferation.pflugers archiv-european journal of physiology2013;465(2):221-232
  4. Meiliang Li,Xiaoling Jia (賈瀟凌), Jingyun Yang , Jianjun Deng and Guanghua Zhao. Effect of tannic acid on properties of soybean (Glycine max) seed ferritin: A model for interaction between naturally-occurring components in foodstuffs.Food Chemistry2012;133:410-415 (Co-first)
  5. Chenyan Lv,Xiaoling Jia (賈瀟凌), Meiliang Li, Jingyun Yang and Guanghua Zhao. Optimization of extraction process of crude protein from grape seeds by RSM.Food Science and Technology Research2011;17:437-445(Co-first)
  6. Xiaoling Jia (賈瀟凌),Chenguang Zhao, Ping Li,et al. Sustained release of VEGF by coaxial electrospun dextran/PLGA fibrous membranes in vascular tissue engineering.Journal of biomaterial science-polymer edition.2011;22:1811-1827
  7. Xiaoling Jia (賈瀟凌), Juan Chen and Mian Long. IL-8-induced L-selectin shedding regulates its binding kinetics to PSGL-1.Chinese Science Bulletin.2009,54:2787-2793
  8. Xin Gu,Xiaoling Jia (賈瀟凌), Jiannan Feng,et al.Molecular modeling and affinity determination of scFv antibody: proper linker peptide enhances its activity.Annals of Biomedical Engineering2010, 38:537-49. (Co-first)
  9. Xiaoling Jia (賈瀟凌), Jingyun Yang, Liu Yang, Ping Li, Wei Song and Yubo Fan. Irrelevance of BK channel expression to VSMCs phenotype under shear stress. World congress on Medical physics and biomedical engineering, Beijing, china, may 2012:26-31.
  10. Li Wu, BotaoXiao,Xiaoling Jia(賈瀟凌),et al.Impact of carrier stiffness and microtopology on two-dimensional kinetics of P-selectin and P-selectin glycoprotein ligand-1 interactions.Journal of biological chemistry2007, 282:9846-9854
  11. Mian Long,Xiaoling Jia. (賈瀟凌)Selectin shedding regulates two-dimensional binding to PSGL-1.Biorheology2008, 45:74-75 , 2008
  12. Yan Huang,Xiaoling Jia(賈瀟凌),Ke Bai,et al. Effects of fluid shear stress on cardiomyogenic differentiation of rat bone marrow mesenchymal stem cellsArchives of medical research.2010 47:497-505.
  13. Ke Bai,Yan Huang,Xiaoling Jia(賈瀟凌),et al.Endothelium oriented differentiation of bone marrow mesenchymal stem cells under chemical and mechanical stimulations.Journal of biomechanics2010,43(6):1176-81
  14. Ping li, Xiaoliang Feng,Xiaoling Jia(賈瀟凌)and Yubo Fan.Influences of Tensile Load onin vitroDegradation of Electrospun Poly(L-Lactide-co-Glycolide)Scaffold.Acta Biomaterialia2010, 6:2991-29969
  15. Yu Zhang, Chen Sang, Katrin Paulsen, Andrea Arenz, Ziyan Zhao,Xiaoling Jia(賈瀟凌), Oliver Ullrich, Fengyuan Zhuang. ICAM-1 expression and organization in human endothelial cells is sensitive to gravityActa Astronautica2010,1073-1080
  16. Xiao Botao; Tong Chunfang;Jia Xiaoling (賈瀟凌), Guo Rui, Lv Shouqin Zhang Yan, McEver Rodger P., Zhu Cheng andLong Mian. Tyrosine Replacement of PSGL-1 Reduces Association Kinetics with P- and L-Selectin on the Cell Membrane.Biophyical Journal2012,103:777-785
  17. Yan Huang, Lisha Zheng, Xianghui Gong,Xiaoling Jia (賈瀟凌), Wei Song, Meili Liu and Yubo Fan. Effect of Cyclic Strain on Cardiomyogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells.PLoS One.2012;7(4):e34960.
  18. Zheng L, Huang Y, Song W, Gong X, Liu M,Jia X(賈瀟凌), Zhou G, Chen L, Li A, Fan Y. Fluid shear stress regulates metalloproteinase-1 and 2 in human periodontal ligament cells: involvement of extracellular signal-regulated kinase (ERK) and P38 signaling pathways.J Biomech. 2012 21;45(14):2368-75.
  19. Xiao B, Tong C, Jia X(賈瀟凌), Guo R, Lü S, Zhang Y, McEver RP, Zhu C, Long M. Tyrosine replacement of PSGL-1 reduces association kinetics with P- and L-selectin on the cell membrane.Biophys J.2012;103(4):777-785.
  20. Ping Li, Lu Jia, Lizhen Liu, Chengguo Liu,Xiaoling Jia(賈瀟凌)and Yubo Fan. Effects of electrical stimulation on growth of endothelial cell. World congress on Medical physics and biomedical engineering, IFMBE Proceedings 29 2013;192-195.
  21. Ping Li, Lizhen Liu, Lu Jia, Yanhui Song,Xiaoling Jia(賈瀟凌)and Yubo Fan. Effects of tensile stimulation and electrical stimulation on the connexion-43 mRNA levels of cardiomyocytes in vitro. World congress on Medical physics and biomedical engineering, IFMBE Proceedings 29 2013;188-191.
  22. Wei Song, Yan Hang,Xiaoling Jia(賈瀟凌), Xianghui Gong, Lisha Zheng and Yubo Fan. Trichostain A and shear stress in regulating endothelium differentiation of bone marrow mensenchymal stem cell. World congress on Medical physics and biomedical engineering, IFMBE Proceedings 29 2013;196-196.
  23. Hongyan Kang, Yubo Fan, Anqiang Sun,Xiaoling Jia (賈瀟凌)and Xiaoyan Deng. Simulated Microgravity Exposure Modulates the Phenotype of Cultured Vascular Smooth Muscle Cells.Cell Biochemistry and Biophysics2013;66(1):121-30
  24. Fan J,Jia X(賈瀟凌), Huang Y, Fu BM, Fan Y. Greater scaffold permeability promotes growth of osteoblastic cells in a perfused bioreactor.J Tissue Eng Regen Med.2013 doi: 10.1002/term.1701
  25. Wang J, Ma J, Dong L, Hou Y,Jia X (賈瀟凌), Niu X, Fan Y Effect of anatase TiO2 nanoparticles on the growth of RSC-364 rat synovial cell.J Nanosci Nanotechnol.2013;13(6):3874-9
  26. Liu M, Song W, Li P, Huang Y, Gong X, Zhou G,Jia X(賈瀟凌), Zheng L, Fan . Galanin protects against nerve injury after shear stress in primary cultured rat cortical neuronsPLoS One.2013; 8(5):e63473.
  27. Liu L, Li P, Zhou G, Wang M,Jia X(賈瀟凌), Liu M, Niu X, Song W, Liu H, Fan Y.Increased proliferation and differentiation of pre-osteoblasts MC3T3-E1 cells on nanostructured polypyrrole membrane under combined electrical and mechanical stimulation.J Biomed Nanotechnol. 2013 Sep;9(9):1532-9.
獲得科研基金情況
  1. 國家自然科學青年基金“IKca通道在周期性牽張致血管平滑肌細胞增殖、遷移及表型轉變中的作用及機制研究”，90萬，2014.01- 2017.12
  2. 國家自然科學青年基金“切應力對平滑肌細胞BKca通道的影響及β1、β3整合素在其中所起的作用”，44萬，2010.01- 2012.12
  3. 教育部（博士點基金）“炎症介質刺激下白細胞表面L-選擇素的表達、分布和動力學變化的研究”，3.6萬，2009.01-2011.12

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