基本介紹
- 中文名：詹心琪
- 畢業院校：廈門大學
- 學位/學歷：博士
- 職業：教師
- 專業方向：有機小分子螢光探針的設計、合成及其在生物成像中的套用
- 任職院校：廈門大學
個人經歷,學習經歷,工作經歷,研究方向,學術成果,代表性成果,主持課程,授權專利,文章列表,
個人經歷
學習經歷
1999 ~2002 廈門大學環境科學學院 環境科學與工程專業 碩士學位
2003 ~2010 廈門大學化學化工學院 分析化學專業 理學博士學位
工作經歷
1988 ~ 2004 閩南師範大學化學系助理教授、副教授
2004 ~ 至今 廈門大學醫學院 助理教授、副教授
2013 ~2014 美國伊利諾伊大學香檳分校訪問學者（國家留學基金委全額資助）
研究方向
有機小分子螢光探針的設計、合成及其在生物成像中的套用。尤其興趣於具有組織穿透力強的長波長發射特性的螢光探針、以及具有雙波長發射特性的能套用於組織細胞中進行精確定量測量的比率型螢光探針的開發研究；光學分子感測與分子識別理論研究。
學術成果
代表性成果
1.Lin Qing-Shuang, Huang Yue-Lin, Fan Xiao-Xing, Zheng Xiao-Lan, Chen, Xiao-Lan, Zhan Xin-Qi*, Zheng Hong*. A ratiometric fluorescent probe for hypochlorous acid determination: Excitation and the dual-emission wavelengths at NIR region. Talanta 2017, 170, 496-501.
2. Zhan Xin-Qi*,Su Bing-Yuan, Zheng Hong, Yan Jiang-Hua. Sensing hydrogen peroxide involving intramolecular charge transfer pathway: A boronate-functioned styryl dye as a highly selective and sensitive naked-eye sensor. ANALYTICA CHIMICA ACTA2010,658 (2), 175-179.
3.Zhan Xin-Qi, Yan, Jiang-Hua, Su, Jin-Hua, Wang, Yi-Chen, He, Jing, Wang, Sheng-Yu, Zheng Hong, Xu Jin-Gou*. Thiospirolactone as a recognition site Rhodamine B-based fluorescent probe for imaging hypochlorous acid generated in human neutrophil cells.SENSORS AND ACTUATORS B-CHEMICAL 2010, 150(2), 774-780.
4. Zhan Xin-Qi, Qian Zhen-Hua, Zheng Hong*, Xu Jin-Gou* Rhodamine thiospirolactone. Highly selective and sensitive reversible sensing of Hg(II). CHEMICAL COMMUNICATIONS 2008,16, 1859-1861.(被引頻次153)
主持課程
- 國家自然科學基金面上項目:“動脈粥樣硬化因子的智慧型螢光探針及活體分子成像”，主持人，(81071202, 2011.01 - 2013.12, 已結題)。
- 福建省自然科學基金：“基於螺環內醯胺及內酯新穎的“閉-開環”機制的光學分子探針研究”，主持人，2008-2010, 已結題。
授權專利
1. 硫代螺環內酯在細胞內次氯酸檢測中的套用。詹心琪，鄭洪，許金鉤，授權（公告）號： CN 101870864 B, 授權（公告）日： 2013. 06. 19；
2. 檢測次氯酸的螢光探針及其製備方法。鄭洪, 詹心琪, 王淑萍，授權（公告）號: CN102382641A, 授權（公告）日: 2012.03.21；
3. 基於部花菁的檢測次氯酸的螢光探針及其製備方法。鄭洪, 王淑萍, 詹心琪，授權（公告）號: CN102391855A, 授權（公告）日: 2012.03.21
文章列表
1. A ratiometric fluorescent probe for hypochlorous acid determination: Excitation and the dual-emission wavelengths at NIR region. Lin, Qing-Shuang; Huang, Yue-Lin; Fan, Xiao-Xing, Zhan, Xin-Qi*; Zheng Hong*.TALANTA 2017，170，496-501.
2.Semicarbazide-based naphthalimide as a highly selective and sensitive colorimetric and "turn-on" fluorescent chemodosimeter for Cu2+. Hu, Xiao-Xiao; Zheng, Xiao-Lan; Fan, Xiao-Xing; Zhan Xin-Qi, Zheng Hong*. SENSORS AND ACTUATORS B-CHEMICAL 2016,227,191-197.
3. A near infrared colorimetric and fluorometric probe for organophosphorus nerve agent mimics by intramolecular amidation. Hu, Xiao-Xiao; Su, Yue-Ting; Ma, Yun-Wei; Zhan, Xin-Qi;Zheng, Hong; Jiang, Yun-Bao. CHEMICAL COMMUNICATIONS 2015,51(82),15118-1512 4. Advances in modifying fluorescein and rhodamine fluorophores as fluorescent chemosensorsZheng, Hong;Zhan, Xin-Qi; Bian, Qing-Na;Zhang, Xiao-Juan. CHEMICAL COMMUNICATIONS2013, 49(5), 429-447.
5.Thiospirolactone as a recognition site Rhodamine B-based fluorescent probe for imaging hypochlorous acid generated in human neutrophil cells. Zhan, Xin-Qi; Yan, Jiang-Hua; Su, Jin-Hua, et al. SENSORS AND ACTUATORS B-CHEMICAL2010, 150 （2）, 774-780.
6. Sensing hydrogen peroxide involving intramolecular charge transfer pathway: A boronate-functioned styryl dye as a highly selective and sensitive naked-eye sensor. Zhan, Xin-Qi; Su, Bing-Yuan; Zheng, Hong; et al. ANALYTICA CHIMICA ACTA，2010,658(2),175-179.
7. 3 ',6 '-Bis(diethylamino)-3H-spiro[2-benzothiophene-1,9 '-xanthene]-3-thione. Su, Bing-Yuan; Zhan, Xin-Qi; Guo, Jian-Nan;et al. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE2008, 64(11),O2068-U1468.
8. Rhodamine thiospirolactone. Highly selective and sensitive reversible sensing of Hg(II). Zhan, Xin-Qi; Qian, Zhen-Hua; Zheng, Hong; Xu, Jin-Gou. CHEMICAL COMMUNICATIONAS, 2008,16,1859-1861.
9. Fluorimetric determination of nitrogen oxides in the air by a novel red-region fluorescent reagent. Zhan, XQ; Li, DH; Zheng, H; Xu, JG. TALANTA2002,58(5), 855-860.
10. Fluorimetric determination of sulfite by the co-quenching effect of formaldehyde and sulfite on the fluorescence of tetra-substituted amino aluminum phthalocyanine. Zhan, XQ; Li, DH; Zheng, H; Xu, JG.ANALYTICA CHIMICA ACTA2001,448:1-2,71-77.
11. Tetrasubstituted sulphonated aluminum phthalocyanine-cationic surfactant system for fluorimetric determination of ethanol in alcoholic beverage. Zhan, XQ; Li, DH; Zhu, QZ; Xu, JG. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY2001,29:6,710-712.
12. A sensitive fluorimetric method for the determination of nitrite and nitrate in seawater by a novel red-region fluorescence dye. Zhan, XQ;Li, DH; Zheng, H; Xu, JG. ANALYTICAL LETTERS, 2001,34:15,2761-277.
13. Sensitive fluorimetric determination of formaldehyde by the co-quenching effect of formaldehyde and sulfite on the fluorescence of tetra-substituted amino aluminium phthalocyanine. Zhan, XQ; Li, DH; Zhu, QZ; Xu, JG. ANALYST2000,125:12,2330-2334.
