人物經歷
2012.4~今 院長助理北京大學公共衛生學院。
2014.7~今 教授 博導 北京大學公共衛生學院營循煉院養與食品衛生學系。
2007.7~2014.7 副教授 碩笑喇嬸導 北京大學公共衛生學院營養與食品衛生學系。
2005.7~2007.7 講師 北京大學公共衛生學院營養與食品衛生學系。
許雅君是北京大學營養與食品衛生學博士。北京大學公共衛生學院院長寒危槓助理;營養與食品衛生學系黨支部書記;北京大學預防醫學實驗教學中心副主任;北京市食品安全毒理學研究與評價重點實驗室副主任。
2005年於北京大學 獲營養與食品衛生學 博士學位。
2000年 於北辨陵乃埋京大學 獲預防醫學 學士學位。
主要成就
科研成就
主要的研究方向包括:婦幼營養、食物活性物質、功能食品。
主要研究包括生她兵照命早期營養對一生健康的影響,動物模型研究和人群研究相結合,探討生命早期最佳化的營養模式,以降低成年後慢性疾病發生風險。
項目時間 | 項目名稱 | 項目來源 |
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| 槲皮素對肥胖大鼠後代出生缺陷的拮抗作用及其機制研究 | |
| 炎性反應機制在肥胖大鼠後代出生缺陷和糖脂代謝紊亂發生中的作用研究 | |
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| 基於毒作用機制和健康效應終點的食品稀土元素和添加劑的安全性評估 | |
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1. Zhang M, Liu W, Zhou Y, Li Y, Qin Y and Xu Y*. Neurodevelopmental toxicity induced by maternal PM2.5 exposure and protective effects of quercetin and Vitamin C. Chemosphere. 2018, 213:182-196.
2. Liu W, Zhang M, Feng J, Fan A, Zhou Y and Xu Y*. The Influence of Quercetin on Maternal Immunity, Oxidative Stress, and Inflammation in Mice with Exposure of Fine Particulate Matter during Gestation. Int. J. Environ. Res. Public Health 2017, 14(6): 592.
3. Xu D, Lyu Y, Chen X, Zhu X, Feng J and Xu Y*. Fructus Ligustri Lucidi ethanol extract inhibits osteoclastogenesis in RAW264.7 cells via the RANKL signaling pathway. Molecular Medicine Reports 2016,14: 4767-4774.
4. Xu L, Dong W, Zhao J and Xu Y*. Effect of Marine Collagen Peptides on Physiological and Neurobehavioral Development of Male Rats with Perinatal Asphyxia. Mar. Drugs 2015, 13(6): 3653-3671.
5. Wu Z, Zhao J, Xu H, Lyv Y, Feng X, Fang Y and Xu Y*. Maternal quercetin administration during gestation and lactation decrease endoplasmic reticulum stress and related inflammation in the adult offspring of obese female rats. European Journal of Nutrition 2014,53(8):1669-1683.
6. Yyu Y, Feng X, Zhao P, Wu Z, Xu H, Fang Y, Hou Y, Denny L and Xu Y*. Fructus Ligustri Lucidi (FLL) ethanol extract increases bone mineral density and improves bone properties in growing female rats. Journal of Bone and Mineral Metabolism 2014, 32(6): 616-626.
7. Feng X, Yyu Y, Wu Z, Fang Y, Xu H, Zhao P and Xu Y*. Fructus ligustri lucidi ethanol extract improves bone mineral density and properties through modulating calcium absorption related genes expression in kidney and duodenum of growing rats. Calcified Tissue International 2014 Apr;94(4):433-441.
8. Dong W, Wu Z, Xu L, Fang Y and Xu Y*. Maternal supplementation of nucleotides improves the behavioral development of prenatal ethanol-exposed mice. Cognitive, Affective, and Behavioral Neuroscience 2014,14(2): 879-890.
9. Zhao J, Zhao J and Xu Y*. Exogenous Nucleotides Antagonize the Developmental Toxicity of Ethanol In Vitro. BioMed Research International 2013, 2013: 204187.
10. Xu Y, Tang Y, Li Y. Effect of folic acid on prenatal alcohol-induced modification of brain proteome in mice. British J nutrition. 2008,99(3):455-461.
11.Zhou Y, Zhu X, Qin Y, Li Y, Zhang M, Liu W, Huang H and Xu Y*. Association between Total Water Intake and Dietary Intake of Pregnant and Breastfeeding Women in China: A Cross-sectional Survey. BMC Pregnancy and Childbirth. 2019, 19:172.
12. Zhou Y, Zhu X, Qin Y, Li Y, Zhang M, Liu W, Huang H and Xu Y *. Association between dietary inflammatory index and bone density in lactating women at 6 months postpartum: a longitudinal study. BMC Public Health. 2019, 19:1076.
13. Zhou Y, Zhang MJ, Liu W, Li Yong, Qin Y, Xu Y *. Transgenerational transmission of neurodevelopmental disorders induced by maternal exposure to PM2.5. Chemosphere. 2020,255:126920.
14. Liu W, Sun H, Zhou Y, Li Y, Yong Qin, Li R, Chen Y, Yu L, Zhao M, Zhang W and Xu Y*. Goat Milk Consumption Ameliorated Abnormalities in Glucose Metabolism and Enhanced Hepatic and Skeletal Muscle AMPK Activation in Rats Fed with High-fat Diets. Molecular Nutrition and Food Research.2019, 63:1900073.
15. Liu W, Zhou Y, Qin Y, Li Y, Yu L, Li R, Chen Y, Xu Y*. Sex-Dependent Effects of PM2.5 Maternal Exposure and Quercetin Intervention on Offspring’s Short Chain Fatty Acids. Int. J. Environ. Res. Public Health 2019, 16, 4371.
16. Liu W, Zhou Y, Li Y, Qin Y, Yu L, Li R, Chen Y and Xu Y*. Effects of PM2.5 exposure during gestation on maternal gut microbiota and pregnancy outcomes. Chemosphere. 2020,247: 125879.
17. Liu W, Zhang M, Zhou Y, Li Y, Qin Y and Xu Y*. Sex-dependent effects of PM2.5 maternal exposure on offspring’s serum lipoproteins and gut microbiota. Science of the Total Environment. 2020,739: 139982.
18. Yu L, Li R, Liu W, Zhou Y, li Y, Qin Y, Chen Y and Xu Y*. Protective Effects of Wheat Peptides against Ethanol-Induced Gastric Mucosal Lesions in Rats: Vasodilation and Anti-Inflammation. Nutrients. 2020,12(8):2355.
19. Liu W, Zhou Y, Qin Y, Yu L, Li R, Chen Y and Xu Y*. Quercetin Intervention Alleviates Offspring’s Oxidative stress, Inflammation, and Tight Junctions Damage in the Colon that were Induced by Maternal PM2.5 Exposure through the Reduction of Bacteroides. Nutrients. 2020,12(10):3095.
20. Li R, Zhou Y, Liu W, Li Y, Qin Y, Yu L, Chen Y and Xu Y*.Rare earth element lanthanum protects against atherosclerosis induced by high-fat diet via down- regulating MAPK and NF-κB pathways. Ecotoxicology and Environmental Safety. 2021,207:111195.
21. Li R, Yu L, Qin Y, Zhou Y, Liu W, Li Y, Chen Y and Xu Y*. Protective effects of rare earth lanthanum on acute ethanol-induced oxidative stress in mice via Keap 1/Nrf2/p62 activation. Science of the Total Environment. 2021,758:143626.
科技成果獎
(1) 2011年 北京市科學技術獎 二等獎 《乙醇致畸機理和干預的基礎研究》。
(2) 2011年 中華醫學科技獎 三等獎《酒精毒性機理和干預的基礎研究》。
(3) 2011年 中華預防醫學科學技術二等獎 《中國常見出生缺陷的發生和預防基礎研究》。
(4) 2011年 教育部高等學校科學研究優秀成果獎 自然科學獎 二等獎 《中國常見出生缺陷病因學和預防基礎研究》。
(5) 2011年華夏科技獎三等獎《中國常見出生缺陷的基礎研究》。
(6) 2013年中華預防醫學會科學技術獎二等獎 《小分子生物活性短肽的產學研集成研究》。
(7) 2014年中國營養學會科學技術獎二等獎《生物活性短肽的產學研集成研究》。
(8) 2014年中華醫學科技獎三等獎《生物活性短肽的產學研集成研究》。
人才培養
校內課程:《營養與食品衛生學》、《預防醫學導論》、《身邊的營養學翻轉課堂》、《舌尖上的安全》、《生命早期營養》、《營養與疾病》等
教育是一份事業,需要全身心投入;教育是一門藝術,需要不斷地創新。
榮譽表彰
時間 | 獲得獎項 |
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| 主講慕課《身邊的營養學》獲"中華醫學會全國醫學教育技術優秀成果獎"一等獎 |
| 《身邊的營養學》慕課獲得“2015全球MOOC排行榜 TOP50最受歡迎的慕課” |
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社會任職
時間 | 擔任職務 |
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| 中國環境誘變劑學會常務理事、科普工作委員會主任委員、暴露組學專委會副主任委員 |
| 教育部農村義務教育學生營養改善計畫專家委員會專家委員 |
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| 全國特殊膳食標準化技術委員會(SAC/TC466)委員 |
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| 國家環境保護部化學物質環境管理評審專家委員會評審專家 |
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3. Xu D, Lyu Y, Chen X, Zhu X, Feng J and Xu Y*. Fructus Ligustri Lucidi ethanol extract inhibits osteoclastogenesis in RAW264.7 cells via the RANKL signaling pathway. Molecular Medicine Reports 2016,14: 4767-4774.
4. Xu L, Dong W, Zhao J and Xu Y*. Effect of Marine Collagen Peptides on Physiological and Neurobehavioral Development of Male Rats with Perinatal Asphyxia. Mar. Drugs 2015, 13(6): 3653-3671.
5. Wu Z, Zhao J, Xu H, Lyv Y, Feng X, Fang Y and Xu Y*. Maternal quercetin administration during gestation and lactation decrease endoplasmic reticulum stress and related inflammation in the adult offspring of obese female rats. European Journal of Nutrition 2014,53(8):1669-1683.
6. Yyu Y, Feng X, Zhao P, Wu Z, Xu H, Fang Y, Hou Y, Denny L and Xu Y*. Fructus Ligustri Lucidi (FLL) ethanol extract increases bone mineral density and improves bone properties in growing female rats. Journal of Bone and Mineral Metabolism 2014, 32(6): 616-626.
7. Feng X, Yyu Y, Wu Z, Fang Y, Xu H, Zhao P and Xu Y*. Fructus ligustri lucidi ethanol extract improves bone mineral density and properties through modulating calcium absorption related genes expression in kidney and duodenum of growing rats. Calcified Tissue International 2014 Apr;94(4):433-441.
8. Dong W, Wu Z, Xu L, Fang Y and Xu Y*. Maternal supplementation of nucleotides improves the behavioral development of prenatal ethanol-exposed mice. Cognitive, Affective, and Behavioral Neuroscience 2014,14(2): 879-890.
9. Zhao J, Zhao J and Xu Y*. Exogenous Nucleotides Antagonize the Developmental Toxicity of Ethanol In Vitro. BioMed Research International 2013, 2013: 204187.
10. Xu Y, Tang Y, Li Y. Effect of folic acid on prenatal alcohol-induced modification of brain proteome in mice. British J nutrition. 2008,99(3):455-461.
11.Zhou Y, Zhu X, Qin Y, Li Y, Zhang M, Liu W, Huang H and Xu Y*. Association between Total Water Intake and Dietary Intake of Pregnant and Breastfeeding Women in China: A Cross-sectional Survey. BMC Pregnancy and Childbirth. 2019, 19:172.
12. Zhou Y, Zhu X, Qin Y, Li Y, Zhang M, Liu W, Huang H and Xu Y *. Association between dietary inflammatory index and bone density in lactating women at 6 months postpartum: a longitudinal study. BMC Public Health. 2019, 19:1076.
13. Zhou Y, Zhang MJ, Liu W, Li Yong, Qin Y, Xu Y *. Transgenerational transmission of neurodevelopmental disorders induced by maternal exposure to PM2.5. Chemosphere. 2020,255:126920.
14. Liu W, Sun H, Zhou Y, Li Y, Yong Qin, Li R, Chen Y, Yu L, Zhao M, Zhang W and Xu Y*. Goat Milk Consumption Ameliorated Abnormalities in Glucose Metabolism and Enhanced Hepatic and Skeletal Muscle AMPK Activation in Rats Fed with High-fat Diets. Molecular Nutrition and Food Research.2019, 63:1900073.
15. Liu W, Zhou Y, Qin Y, Li Y, Yu L, Li R, Chen Y, Xu Y*. Sex-Dependent Effects of PM2.5 Maternal Exposure and Quercetin Intervention on Offspring’s Short Chain Fatty Acids. Int. J. Environ. Res. Public Health 2019, 16, 4371.
16. Liu W, Zhou Y, Li Y, Qin Y, Yu L, Li R, Chen Y and Xu Y*. Effects of PM2.5 exposure during gestation on maternal gut microbiota and pregnancy outcomes. Chemosphere. 2020,247: 125879.
17. Liu W, Zhang M, Zhou Y, Li Y, Qin Y and Xu Y*. Sex-dependent effects of PM2.5 maternal exposure on offspring’s serum lipoproteins and gut microbiota. Science of the Total Environment. 2020,739: 139982.
18. Yu L, Li R, Liu W, Zhou Y, li Y, Qin Y, Chen Y and Xu Y*. Protective Effects of Wheat Peptides against Ethanol-Induced Gastric Mucosal Lesions in Rats: Vasodilation and Anti-Inflammation. Nutrients. 2020,12(8):2355.
19. Liu W, Zhou Y, Qin Y, Yu L, Li R, Chen Y and Xu Y*. Quercetin Intervention Alleviates Offspring’s Oxidative stress, Inflammation, and Tight Junctions Damage in the Colon that were Induced by Maternal PM2.5 Exposure through the Reduction of Bacteroides. Nutrients. 2020,12(10):3095.
20. Li R, Zhou Y, Liu W, Li Y, Qin Y, Yu L, Chen Y and Xu Y*.Rare earth element lanthanum protects against atherosclerosis induced by high-fat diet via down- regulating MAPK and NF-κB pathways. Ecotoxicology and Environmental Safety. 2021,207:111195.
21. Li R, Yu L, Qin Y, Zhou Y, Liu W, Li Y, Chen Y and Xu Y*. Protective effects of rare earth lanthanum on acute ethanol-induced oxidative stress in mice via Keap 1/Nrf2/p62 activation. Science of the Total Environment. 2021,758:143626.