蘇志恆

博士，副教授，廣西醫科大學碩士生導師

基本介紹

• 中文名：蘇志恆
• 國籍：中國
• 民族：漢族
• 出生地：廣西 南寧
• 出生日期：1981年11月
• 學位/學歷：博士
• 職務：廣西醫科大學海洋藥物研發中心副主任

個人簡介

博士，副教授，廣西醫科大學碩士生導師

海洋藥物研發中心副主任

藥物分析學科負責人

國家自然科學基金項目評議專家

廣西科技項目評審專家

廣西青年聯合會委員

致公黨廣西醫科大學副主任委員

受教育經歷

2000/09–2004/06，瀋陽藥科大學，中藥學院，中藥學，學士
2004/09–2007/06，瀋陽藥科大學，中藥學院，中藥學，碩士
2007/09–2010/06，北京協和醫學院，中國醫學科學院藥用植物研究所，生藥學，博士

研究方向

1.代謝組學分析技術的套用

2.基於組效關係的中藥及民族藥活性成分分析

3.海洋健康產品研究與開發

在研及結題課題

1. 國家自然科學基金青年基金（基於代謝網路“時-空”動態調控的當歸四逆湯“溫經通脈”作用配伍機制及其藥效物質基礎研究（81603533）），在研。
2. 國家自然科學基金地區基金（基於二維"組效關係"的柴胡疏肝散抗抑鬱藥效成分群及配伍規律研究（81360638）），在研。
3. 廣西自然科學基金青年基金（基於代謝組學的柚皮苷抗抑鬱作用機制研究(2012GXNSFBA053108）），已結題。
4. 廣西教育廳高校科研項目（基於定量代謝組學的柚皮苷抗抑鬱作用機制研究（200103YB026）），已結題。
5. 廣西醫科大學青年基金（基於代謝組學的柚皮苷抗抑鬱作用機制研究（02602211014）），已結題。
另先後作為主要人員參與國家自然基金、教育部博士點基金、海口市重點科技項目等多項課題研究。

近5年主要發表論文

1. Fang Wu, Hua Zheng, Zheng-Teng Yang, Bang Cheng, Jin-Xia Wu, Xu-Wen Liu, Chao-Ling Tang, Shi-Yin Lu, Zhao-Ni Chen, Fang-Ming Song, Jun-Xiang Ruan, Hong-Ye Zhang, Yong-Hong Liang, Hui Song, Zhi-Heng Su▲. Urinary metabonomics study of the hepatoprotective effects of total alkaloids from Corydalis saxicola Bunting on carbontetrachloride-induced chronic hepatotoxicity in rats using 1H NMR analysis. Journal of Pharmaceutical and Biomedical Analysis 140 (2017) 199–209 （通訊作者）
   
2. Yong-Hong Liang, Chao-Ling Tang, Shi-Yin Lu, Bang Cheng, Fang Wu, Zhao-Ni Chen, Fang-ming Song, Jun-Xiang Ruan, Hong-YeZhang, Hui Song, Hua Zheng, Zhi-Heng Su▲. Serum metabonomics study of the hepatoprotective effect of Corydalissaxicola Bunting on carbon tetrachloride-induced acute hepatotoxicity in rats by 1H NMR analysis. Journal of Pharmaceutical and Biomedical Analysis 129 (2016) 70–79. （通訊作者）
   
3. Zhang H, Zheng H, Zhao G, Tang C, Lu S, Cheng B, WuF, Wei J, Liang Y, Ruan J, Song H, Su Z▲.Metabolomic study of corticosterone-induced cytotoxicity in PC12 cells by ultra performance liquid chromatography-quadrupole/time-of-flight mass spectrometry. Mol Biosyst. 2016, 12(3): 902-13. （通訊作者）
   
4. Jin-Bin Wei, Xiong Li, Hui Song, Yong-Hong Liang, Yu-Zheng Pan, Jun-Xiang Ruan, Xia Qin, Yong-Xin Chen, Cai-Li Nong, Zhi-Heng Su▲. Characterization and determination of antioxidant components in the leaves of Camellia chrysantha (Hu) Tuyama based on composition–activity relationship approach. Journal of Food and Drug Analysis. 2015, 23 (1): 40-48 （通訊作者）
   
5. Zhi-heng Su, Hong-mei Jia, Hong-wu Zhang, Yu-fei Feng, Lei An and Zhong-mei Zou. Hippocampus and serum metabolomic studies to explore the regulation of Chaihu-Shu-Gan-San on metabolic network disturbances of rats exposed to chronic variable stress. Molecular BioSystems, 2014, 10 (3), 549-561.
   
6. Zhi-Heng Su, Shu-Qi Li, Guo-An Zou, Chang-Yuan Yu, Yan-Guo Sun, Hong-Wu Zhang, Ying Gu, Zhong-Mei Zou. Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats, Journal of Pharmaceutical and Biomedical Analysis 2011, 55 (3): 533-539.
   
7. Zhi-Heng Su, Guo-An Zou, Hong-Wu Zhang, Zhong-Mei Zou. Online identification of the antioxidant constituents of traditional Chinese medicine formula Chaihu-Shu-Gan-San by LC-LTQ-Orbitrap mass spectrometry and microplate spectrophotometer. Journal of Pharmaceutical and Biomedical Analysis 2010, 53(3): 454-461.
   
8. Hong-mei Jia, Zhi-heng Su, Wei-Long, Yue-tao Liu, Xing Chang, Hong-wu Zhang, Gang Ding, Yu-fei Feng, Da-yong Cai, and Zhong-mei Zou. Metabonomics combined with UPLC-MS chemical profile for discovery of antidepressant ingredients of a traditional Chinese medicines formula, Chaihu-Shu-Gan-San. Evidence-Based Complementary and Alternative Medicine, 2013; 2013: 487158.
   
9. Qi Tang, Zhi-heng Su, Zhen-tai Han, Xiao-jun Ma, De-rong Xu, Yan-hai Liang, Hai-bo Cao, Xue-song Wang, Xiao-ying Qu, Angela Hoffman, Hong-wei Liu, Di-zhou Gu, De-you Qiu. LC–MS method for detecting prostratin in plant extracts and identification of a high-yielding population of Euphorbia fischeriana. Phytochemistry Letters, 2012, 5(1): 214-218.
   
10. Zou GA, Ding G, Su ZH, Yang JS, Zhang HW, Peng CZ, Aisa HA, Zou ZM. Lactonecembranoids from Croton laevigatus. J Nat Prod. 2010 Apr 23; 73(4): 792-5.
    
11. Guo-An Zou, Zhi-Heng Su, Hong-Wu Zhang, Yuan Wang, Jun-Shan Yang, Zhong-Mei Zou. Flavonoids from the Stems of Croton caudatus Geisel. var. tomentosus Hook. Molecules 2010, 15(3): 1097-1102.
    
12. S. Q. Li, Z. H. Su, J. B. Peng, Z. M. Zou, C. Y. Yu, In Vitro and in Vivo Antioxidant Effects and the Possible Relationship between the Antidepression Efficacy of Traditional Chinese Medicine Formulation Chai-hu-Shu-gan-San, Chin. J. Nat. Med., 8(2010) 353-361.