蔡宇傑，副教授，研究發酵工程、生化工程、下游工程、生物信息等方面的交叉學科。
基本介紹
- 中文名：蔡宇傑
- 國籍：中國
- 民族：漢族
- 職業：副教授
- 性別：男
- 政治面貌：民眾
主持項目,主講課程,研究領域,主要論著,鑑定,所獲專利,
主持項目
1. 集成化通用型智慧型模擬移動床色譜裝置開發與產業化，江蘇省科技攻關重點項目，BE2006070 （2006,4-2007,12）
2. 生物、醫套頁汽藥用模擬移動床色譜分離和擔墊察純化裝置關鍵技術開發及產業化,江蘇省科技成果轉化重大專項項目碑辨殃，BA2007077 （2007,10-2010,9）
3. 竹黃菌全細胞催化合成竹紅菌素關鍵技術研究,科技部科技人員服務企業項目，2009GJ10038 （2009,5-2010,5）
4. 基於蛋白質組差異分析方法的竹紅菌素代謝途徑關鍵催化過程研究，國駝灑辣家自然訂定采科學基金，21045007 （2011,1-2011,12）
5. 廣譜抗癌新藥竹紅菌素全細胞合成及純化關鍵技術研究,江蘇省科技創新與成果轉化（重大科技支撐與自主創新）專項引導資金，BY2010117 （2010,7-2012,12）
6. 中央高校基本科研業務費專項資金資助 JUSRP21120 （2011,1-2012,12）
主講課程
計算機在生物工程中的套用，生物化學實驗
研究領域
主要蒸她汽妹課題：（1）天然產物發酵及性能：竹紅菌素、蟲草辯櫃素、不飽和脂肪酸等（2）酶的發酵與性質：漆酶、SOD酶等
主要論著
[1] Cai YJ, Liao XR, Liang XH, Ding YR, Sun J, Zhang DB. Induction of hypocrellin production by Triton X-100 under submerged fermentation with Shiraia sp. SUPER-H168. New Biotechnol 2011,
[2] Cai YJ, Liu S, Liao X, Ding Y, Sun J, Zhang D. Purification and partial characterization of antifreeze proteins from leaves of Ligustrum lucidum Ait. Food and Bioproducts Processing 2011, 89, 98-102
[3] Cai YJ, Wu HG, Liao XR, Ding YR, Sun J, Zhang DB. Purification and Characterization of Novel Manganese Peroxidase from Rhizoctonia sp. SYBC-M3. Biotechnol Bioprocess Eng 2010, 15, 1016-1021
[4] Cai YJ, Wei ZY, Liao XR, Ding YR, Sun J. Characterization of three extracellular polysaccharides from Shiraia sp Super-H168 under submerged fermentation. Carbohydr Polym 2010, 82, 34-38
[5] Cai YJ, Liang XH, Liao XR, Ding YR, Sun J, Li XH. High-Yield Hypocrellin A Production in Solid-State Fermentation by Shiraia sp SUPER-H168. Appl Biochem Biotechnol 2010, 160, 2275-2286
[6] Cai YJ, Wang L, Liao XR, Ding YR, Sun J. Purification and partial characterization of two new cold-adapted lipases from mesophilic Geotrichum sp. SYBC WU-3. Process Biochem 2009, 44, 786-790
[7] Cai YJ, Sun J, Wang J, Ding YR, Tian N, Liao XR, Xu WB. Optimizing the codon usage of synthetic gene with QPSO algorithm. J Theor Biol 2008, 254, 123-127
[8] Cai YJ, Ding YR, Tao GJ, Liao XR. Production of 1,5-dihydroxy-3-methoxy-7-methylanthracene-9,10-dione by submerged culture of Shiraia bambusicola. J Microbiol Biotechnol 2008, 18, 322-327
[9] Zeng XK, Cai YJ, Liao XR, Li W, Zhang DB. Decolorization of synthetic dyes by crude laccase from a newly isolated Trametes trogii strain cultivated on solid agro-industrial residue. J Hazard Mater 2011, 187, 517-525
[10] Zeng HW, Cai YJ, Liao XR, Zhang F, Zhang DB. An induced strategy of regulation of carbon metabolism and statistical optimization for production enhancement of catalase by Serratia marcescens SYBC08 from sludge with hydrogen peroxide. Asian Journal of Chemistry 2011, 23, 1488-1492
[11] Zeng HW, Cai YJ, Liao XR, Zhang F, Zhang DB. Production, characterization, cloning and sequence analysis of a monofunctional catalase from Serratia marcescens SYBC08. J Basic Microbiol 2011, 51, 205-214
[12] Li GY, Cai YJ, Liao XR, Yin J. Enzymatic synthesis of sucrose octaacetate using a novel alkaline protease. Biotechnol Lett 2011, 33, 607-610
[13] Hao ZK, Cai YJ, Liao XR, Liang XH, Liu J, Fang Z, Hu MM, et al.Chitinolyticbacter meiyuanensis SYBC-H1(T), Gen. Nov., sp. Nov., a Chitin-Degrading Bacterium Isolated From Soil. Curr Microbiol 2011,
[14] Zeng HW, Cai YJ, Liao XR, Qian SL, Zhang F, Zhang DB. Optimization of catalase production and purification and characterization of a novel cold-adapted Cat-2 from mesophilic bacterium Serratia marcescens SYBC-01. Ann Microbiol 2010, 60, 701-708
[15] Yuan BH, Cai YJ, Liao XR, Yun LH, Zhang F, Zhang DB. Isolation and identification of a cold-adapted lipase producing strain from decayed seeds of Ginkgo biloba L. and characterization of the lipase. Afr J Biotechnol 2010, 9, 2661-2667
[16] Wang ZX, Cai YJ, Liao XR, Zhang F, Zhang D, Li ZL. Production and Characterization of a Novel Laccase with Cold Adaptation and High Thermal Stability from an Isolated Fungus. Appl Biochem Biotechnol 2010, 162
[17] Wang ZX, Cai YJ, Liao XR, Tao GJ, Li YY, Zhang F, Zhang DB. Purification and characterization of two thermostable laccases with high cold adapted characteristics from Pycnoporus sp SYBC-L1. Process Biochem 2010, 45, 1720-1729
[18] Sun J, Zhao J, Wu XJ, Fang W, Cai YJ, Xu WB. Parameter estimation for chaotic systems with a Drift Particle Swarm Optimization method. Physics Letters A 2010, 374, 2816-2822
[19] Su YJ, Rao SQ, Cai YJ, Yang YJ. Preparation and characterization of the inclusion complex of hypocrellin A with hydroxypropyl-beta-cyclodextrin. Eur Food Res Technol 2010, 231, 781-788
[20] Su YJ, Yin XY, Rao SQ, Cai YJ, Reuhs B, Yang YJ. Natural colourant from Shiraia bambusicola: stability and antimicrobial activity of hypocrellin extract. International Journal of Food Science and Technology 2009, 44, 2531-2537
[21] Liang XH, Cai YJ, Liao XR, Wu K, Wang L, Zhang DB, Meng Q. Isolation and identification of a new hypocrellin A-producing strain Shiraia sp SUPER-H168. Microbiol Res 2009, 164, 9-17
[22] Ding DW, Ding YR, Li LN, Cai YJ, Xu WB. Structural and functional analysis of giant strong component of bacillus thuringiensis metabolic network. Braz J Microbiol 2009, 40, 411-416
[23] Ding DW, Ding YR, Lu KZ, Chen SW, Cai YJ, Xu WB. Robustness in B-thuringiensis Metabolic Network. Rivista Di Biologia-Biology Forum 2008, 101, 265-277
[24] Ding DW, Ding YR, Cai YJ, Chen SW, Xu WB. Exploring poly-beta-hydroxybutyrate metabolism through network-based extreme pathway analysis. Rivista Di Biologia-Biology Forum 2008, 101, 67-79
[25] Ding YR, Cai YJ, Zhang GX, Xu WB. The influence of dipeptide composition on protein thermostability. FEBS Lett 2004, 569, 284-288
鑑定
中國教育部鑑定2007,鑒字[教SW200]第095號
江蘇省科學技術廳鑑定2005,蘇科鑒字[2005]第757號
所獲專利
蔡宇傑;廖祥儒;梁曉輝;金大勇;王 蕾;丁彥蕊;孟 強;張大兵,一株產苝醌化合物的竹黃菌株 ZL200710132510.4
蔡宇傑;廖祥儒;梁曉輝;魏兆媛;丁彥蕊;孟 強;王亞輝;張大兵,一種利用竹黃菌發酵生產超氧化物岐化酶的方法 ZL200910031830.
[5] Cai YJ, Liang XH, Liao XR, Ding YR, Sun J, Li XH. High-Yield Hypocrellin A Production in Solid-State Fermentation by Shiraia sp SUPER-H168. Appl Biochem Biotechnol 2010, 160, 2275-2286
[6] Cai YJ, Wang L, Liao XR, Ding YR, Sun J. Purification and partial characterization of two new cold-adapted lipases from mesophilic Geotrichum sp. SYBC WU-3. Process Biochem 2009, 44, 786-790
[7] Cai YJ, Sun J, Wang J, Ding YR, Tian N, Liao XR, Xu WB. Optimizing the codon usage of synthetic gene with QPSO algorithm. J Theor Biol 2008, 254, 123-127
[8] Cai YJ, Ding YR, Tao GJ, Liao XR. Production of 1,5-dihydroxy-3-methoxy-7-methylanthracene-9,10-dione by submerged culture of Shiraia bambusicola. J Microbiol Biotechnol 2008, 18, 322-327
[9] Zeng XK, Cai YJ, Liao XR, Li W, Zhang DB. Decolorization of synthetic dyes by crude laccase from a newly isolated Trametes trogii strain cultivated on solid agro-industrial residue. J Hazard Mater 2011, 187, 517-525
[10] Zeng HW, Cai YJ, Liao XR, Zhang F, Zhang DB. An induced strategy of regulation of carbon metabolism and statistical optimization for production enhancement of catalase by Serratia marcescens SYBC08 from sludge with hydrogen peroxide. Asian Journal of Chemistry 2011, 23, 1488-1492
[11] Zeng HW, Cai YJ, Liao XR, Zhang F, Zhang DB. Production, characterization, cloning and sequence analysis of a monofunctional catalase from Serratia marcescens SYBC08. J Basic Microbiol 2011, 51, 205-214
[12] Li GY, Cai YJ, Liao XR, Yin J. Enzymatic synthesis of sucrose octaacetate using a novel alkaline protease. Biotechnol Lett 2011, 33, 607-610
[13] Hao ZK, Cai YJ, Liao XR, Liang XH, Liu J, Fang Z, Hu MM, et al.Chitinolyticbacter meiyuanensis SYBC-H1(T), Gen. Nov., sp. Nov., a Chitin-Degrading Bacterium Isolated From Soil. Curr Microbiol 2011,
[14] Zeng HW, Cai YJ, Liao XR, Qian SL, Zhang F, Zhang DB. Optimization of catalase production and purification and characterization of a novel cold-adapted Cat-2 from mesophilic bacterium Serratia marcescens SYBC-01. Ann Microbiol 2010, 60, 701-708
[15] Yuan BH, Cai YJ, Liao XR, Yun LH, Zhang F, Zhang DB. Isolation and identification of a cold-adapted lipase producing strain from decayed seeds of Ginkgo biloba L. and characterization of the lipase. Afr J Biotechnol 2010, 9, 2661-2667
[16] Wang ZX, Cai YJ, Liao XR, Zhang F, Zhang D, Li ZL. Production and Characterization of a Novel Laccase with Cold Adaptation and High Thermal Stability from an Isolated Fungus. Appl Biochem Biotechnol 2010, 162
[17] Wang ZX, Cai YJ, Liao XR, Tao GJ, Li YY, Zhang F, Zhang DB. Purification and characterization of two thermostable laccases with high cold adapted characteristics from Pycnoporus sp SYBC-L1. Process Biochem 2010, 45, 1720-1729
[18] Sun J, Zhao J, Wu XJ, Fang W, Cai YJ, Xu WB. Parameter estimation for chaotic systems with a Drift Particle Swarm Optimization method. Physics Letters A 2010, 374, 2816-2822
[19] Su YJ, Rao SQ, Cai YJ, Yang YJ. Preparation and characterization of the inclusion complex of hypocrellin A with hydroxypropyl-beta-cyclodextrin. Eur Food Res Technol 2010, 231, 781-788
[20] Su YJ, Yin XY, Rao SQ, Cai YJ, Reuhs B, Yang YJ. Natural colourant from Shiraia bambusicola: stability and antimicrobial activity of hypocrellin extract. International Journal of Food Science and Technology 2009, 44, 2531-2537
[21] Liang XH, Cai YJ, Liao XR, Wu K, Wang L, Zhang DB, Meng Q. Isolation and identification of a new hypocrellin A-producing strain Shiraia sp SUPER-H168. Microbiol Res 2009, 164, 9-17
[22] Ding DW, Ding YR, Li LN, Cai YJ, Xu WB. Structural and functional analysis of giant strong component of bacillus thuringiensis metabolic network. Braz J Microbiol 2009, 40, 411-416
[23] Ding DW, Ding YR, Lu KZ, Chen SW, Cai YJ, Xu WB. Robustness in B-thuringiensis Metabolic Network. Rivista Di Biologia-Biology Forum 2008, 101, 265-277
[24] Ding DW, Ding YR, Cai YJ, Chen SW, Xu WB. Exploring poly-beta-hydroxybutyrate metabolism through network-based extreme pathway analysis. Rivista Di Biologia-Biology Forum 2008, 101, 67-79
[25] Ding YR, Cai YJ, Zhang GX, Xu WB. The influence of dipeptide composition on protein thermostability. FEBS Lett 2004, 569, 284-288
鑑定
中國教育部鑑定2007,鑒字[教SW200]第095號
江蘇省科學技術廳鑑定2005,蘇科鑒字[2005]第757號
所獲專利
蔡宇傑;廖祥儒;梁曉輝;金大勇;王 蕾;丁彥蕊;孟 強;張大兵,一株產苝醌化合物的竹黃菌株 ZL200710132510.4
蔡宇傑;廖祥儒;梁曉輝;魏兆媛;丁彥蕊;孟 強;王亞輝;張大兵,一種利用竹黃菌發酵生產超氧化物岐化酶的方法 ZL200910031830.
