程家森

程家森，男，1977年12月出生，教授，博士生導師。

基本介紹

• 中文名：程家森
• 國籍：中國
• 民族：漢族
• 出生日期：1977.12
• 性別：男

人物經歷

1996-2000：華中農業大學植保系攻讀學士學位；

2000-2003：在華中農業大學攻讀碩士學位期間主要從事真菌病毒分離克隆及其對寄主影響等方面的研究；

2003-2006：在中山大學攻讀博士學位期間主要從事小RNA在肝癌治療中的作用及其套用研究；

2006年7月博士畢業後留在中山大學任教，主要從事腫瘤轉移相關miRNA的篩選及其功能研究；

2008年9月調入華中農業大學任教，從事分子植物病理學研究，主要方向為核盤菌和灰葡萄孢的致病及發育機理研究；

2013-2014：美國西南醫學中心訪問學者。

研究方向

研究方向為分子植物病理學，主要研究領域為核盤菌與寄主的互作及其分子機制研究、灰葡萄孢的發育與致病機理研究等。

主要貢獻

主持國家自然科學基金面上項目，項目名稱：核盤菌分泌蛋白SSITL抑制寄主抗病反應的分子機理研究（2016-2019）； 主持湖北省自然科學基金面上項目，項目名稱：分泌蛋白SSVP1在核盤菌致病中的作用及其分子機制研究（2015-2016）； 主持公益性行業(農業)科研專項子課題，項目名稱：油料作物菌核病綜合防控技術研究與示範推廣（2011-2015）； 主持公益性行業(農業)科研專項子課題，項目名稱：保護地果蔬灰霉病綠色防控技術研究與示範（2013-2017）； 參加公益性行業(農業)科研專項，項目名稱：油菜菌核病早期診斷技術與成災規律研究（2007-2010）； 主持轉基因生物新品種培育重大專項子課題，項目名稱：從核盤菌生防真菌盾殼霉中克隆抗大豆菌核病的功能基因（2009-2011）； 主持國家自然科學基金青年項目，項目名稱：調控核盤菌菌核形成相關miRNA的克隆及其功能研究（2011-2013）； 現代產業技術體系桃體系流膠病及生理病害防控崗位團隊成員（2009-2015）。

專利

一株防治菌核病的生防菌盾殼霉ZS-1SB及製備方法與套用，ZL200910062405.7; 一種農桿菌介導的核盤菌的遺傳轉化方法，ZL20101017526.3; 一種適用於核盤菌菌株抗藥性檢測試劑盒及檢測核盤菌菌株抗藥性的方法，ZL201010514797.9; 水稻紋枯病生防菌枯草芽孢桿菌WJ-1及菌劑與套用，ZL201010175797.0; 生防真菌盾殼霉產孢相關基因CmPex2及其套用，ZL201010181281.7; 一株水稻紋枯病菌生防菌RS-BC及微生物菌劑與製備方法和套用，ZL201110056038.7; 盾殼霉鐵載體轉運蛋白基因及製備方法和用途，ZL201210081535.7; 一種Microdochium bolleyi F10菌株菌劑及製備方法和套用，ZL201210233680.2; 一種生防菌盾殼霉ZS-1SB菌劑的製備方法與套用，ZL201210123060.3; 一種哈茨木霉Sch234菌株及製備方法和套用，ZL201210112622.4; .一種擬康寧木霉ReTk1菌株及菌劑製備方法和套用，ZL201410487407.1; 一種油菜內生性深綠木霉ReTv2菌株及其製備方法和套用，ZL201410459408.5

論文

*通訊作者，#並列第一作者; 2016年; 1. Yunkun Dang#, Jiasen Cheng#, Xianyun Sun, Zhipeng Zhou, Yi Liu*. 2016. Antisense transcription licenses nascent transcripts to mediate transcriptional gene silencing. Genes & Development 30: 2417-2432.(IF: 10.042); 2. Si Liu, Jiatao Xie, Jiasen Cheng, Bo Li, Tao Chen, Yanping Fu, Guoqing Li,Manqun Wang, Huanan Jin, Hu Wan, Daohong Jiang*. 2016. A Fungal DNA virus infects a mycophagous insect and utilizes it as a transmission vector. Proc Natl Acad Sci U S A. doi/10.1073/pnas.1608013113.(IF: 9.423); 3. Kai Bi, Zhangchao He, Zhixiao Gao, Ying Zhao, Yanping Fu, Jiasen Cheng, Jiatao Xie, Daohong Jiang, Tao Chen*. 2016. Integrated omics study of lipid droplets from Plasmodiophora brassicae. Scientific Reports 6: 36965. doi: 10.1038/srep36965.(IF: 5.228); 4. Tao Chen, Kai Bi, Zhangchao He, Zhixiao Gao, Ying Zhao, Yanping Fu, Jiasen Cheng, Jiatao Xie, Daohong Jiang*. 2016. Arabidopsis mutant bik1 exhibits strong resistance to Plasmodiophora brassicae. Frontiers in Physiology 7: 402.(IF: 4.031); 5. Xiaoli Zhang#, Xinqiang Liu#, Yanli Zhao, Jiasen Cheng, Jiatao Xie, Yanping Fu, Daohong Jiang, Tao Chen*. 2016. Histone H3 Lysine 9 Methyltransferase DIM5 is required for the development and virulence of Botrytis cinerea. Frontiers in Microbiology 7: 1289.(IF: 4.165); 6. Hongchang Ran, Lijiang Liu, Bo Li, Jiasen Cheng, Yanping Fu, Daohong Jiang, Jiatao Xie*. 2016. Co-infection of a hypovirulent isolate of Sclerotinia sclerotiorum with a new botybirnavirus and a strain of a mitovirus. Virology Journal 13: 92, DOI: 10.1186/s12985-016-0550-2.(IF: 2.362); 7. Xiaoxiang Yang , Hui Cui, Jiasen Cheng, Jiatao Xie, Daohong Jiang, Tom Hsiang, and Yanping Fu*. 2016. A HOPS protein, CmVps39, is required for vacuolar morphology, autophagy, conidiogenesis and mycoparasitism of Coniothyrium minitans. Environmental Microbiology DOI: 10.1111/1462-2920.13334.(IF: 5.932); 8. Wei Wei, Wenjun Zhu, Jiasen Cheng, Jiatao Xie, Daohong Jiang, Guoqing Li, Weidong Chen, and Yanping Fu*. 2016. Nox Complex signal and MAPK cascade pathway are cross-linked and essential for pathogenicity and conidiation of mycoparasite Coniothyrium minitans. Scientific Reports 6: 24325. DOI: 10.1038/srep24325.(IF: 5.228); 9. Xueliang Lyu, Cuicui Shen, Yanping Fu, Jiatao Xie, Daohong Jiang, Guoqing Li and Jiasen Cheng*. 2016. A small secreted virulence-related protein is essential for the necrotrophic interactions of Sclerotinia sclerotiorum with its host plants. PLoS Pathogens 12(2): e1005435.(IF: 7.003); 10. Xueliang Lyu, Cuicui Shen, Yanping Fu, Jiatao Xie, Daohong Jiang, Guoqing Li and Jiasen Cheng*. 2016. The microbial opsin homolog Sop1 is involved in Sclerotinia sclerotiorum development and environmental stress response. Frontiers in Microbiology 6: 1504.(IF: 4.165); 2015年; 1. Xueliang Lyu, Cuicui Shen, Yanping Fu, Jiatao Xie, Daohong Jiang, Guoqing Li, and Jiasen Cheng*. 2015. Comparative genomic and transcriptional analyses of the carbohydrate-active enzymes and secretomes of phytopathogenic fungi reveal their significant roles during infection and development. Scientific Reports 5: 15565. DOI: 10.1038/srep15565.(IF: 5.228); 2. Xueliang Lyu, Cuicui Shen, Jiatao Xie, Yanping Fu, Daohong Jiang, Zijin Hu, Lihua Tang, Liguang Tang, Feng Ding, Kunfei Li, Songsong Wu, Yanping Hu, Lilian Luo, Yuanhao Li, Qihua Wang, Guoqing Li, Jiasen Cheng*. 2015. Genes associated with the plant carbon fixation pathway in a fungal plant pathogen. Scientific Reports 5: 12952. DOI: 10.1038/srep12952.(IF: 5.228); 3. Yi Lou, Yongchao Han, Long Yang, Mingde Wu, Jing Zhang, Jiasen Cheng, Moying Wang, Daohong Jiang, Guoqing Li*. 2015. CmpacC regulates mycoparasitism, oxalate degradation and antifungal activity in the mycoparasitic fungus Coniothyrium minitans. Environmenatal Microbiology 17(11): 4711-4729.(IF: 5.932); 4. Minghong Wang, Yong Wang, Xiangzhong Sun, Jiasen Cheng, Yanping Fu, Huiquan Liu, Daohong Jiang, Said Ghabrial, and Jiatao Xie*. 2015. Characterization of a novel megabirnavirus from Sclerotinia sclerotiorum reveals horizontal gene transfer from ssRNA virus to dsRNA virus. Journal of Virology 89(16): 8567-79.(IF: 4.606); 5. Lijiang Liu, Qihua Wang, Jiasen Cheng, Yanping Fu, Daohong Jiang, Jiatao Xie*. 2015. Molecular characterization of a bipartite double-stranded RNA virus and its satellite-like RNA co-infecting the phytopathogenic fungus Sclerotinia sclerotiorum. Frontiers in Microbiology 6: 406.(IF: 4.165); 6. Rong Liu, Jiasen Cheng, Yanping Fu, Daohong Jiang, Jiatao Xie*. 2015. Molecular characterization of a novel positive-sense, single-stranded RNA virus infecting the plant pathogenic fungus Sclerotinia sclerotiorum. Viruses 21, 7 (5): 2470-2484.(IF: 3.042); 7. Zhiyong Xu, Songsong Wu, Lijiang Liu, Jiasen Cheng, Yanping Fu, Daohong Jiang, Jiatao Xie*. 2015. A mitovirus related to plant mitochondrial gene confers hypovirulence on the phytopathogenic fungus Sclerotinia sclerotiorum. Virus Research 197: 127-136.(IF: 2.526); 2014年; 1. Lijiang Liu, Jiatao Xie, Jiasen Cheng, Yanping Fu, Guoqing Li, Xianhong Yi, Daohong Jiang*. 2014. Fungal negative-stranded RNA virus that is related to bornaviruses and nyaviruses. Proc Natl Acad Sci U S A. 111 (33): 12205-12210.(IF: 9.674); 2. Xueqiong Xiao, Jiasen Cheng, Jinghua Tang, Yanping Fu, Daohong Jiang, Timothy S. Baker, Said A. Ghabrial and Jiatao Xie*. 2014. A novel partitivirus that confers hypovirulence on plant pathogenic fungi. Journal of Virology 88(17): 10120-33.(IF: 4.439); 3. Zijin Hu, Songsong Wu, Jiasen Cheng, Yanping Fu, Daohong Jiang, Jiatao Xie*. 2014. Molecular characterization of two positive-strand RNA viruses co-infecting a hypovirulent strain of Sclerotinia sclerotiorum. Virology 464-465: 450-459.(IF: 3.321); 4. Xueqiong Xiao, Jiatao Xie, Jiasen Cheng, Guoqing Li, Xianhong Yi, Daohong Jiang, Yanping Fu*. 2014. Novel secretory protein Ss-Caf1 of the plant-pathogenic fungus Sclerotinia sclerotiorum is required for host penetration and normal sclerotial development. Molecular Plant-Microbe Interactions 27(1): 40-55.(IF: 3.944); 2013年; 1. Xiao Yu#, Bo Li#, Yanping Fu, Jiatao Xie, Jiasen Cheng, Said A. Ghabrial, Li G, Xianhong Yi, Daohong Jiang*. 2013. Extracellular transmission of a DNA mycovirus and its use as a natural fungicide. Proc Natl Acad Sci U S A. 110(4): 1452-1457. (IF: 9.809); 2. Wenjun Zhu, Wei Wei, Yanping Fu, Jiasen Cheng, Jiatao Xie, Guoqing Li, Xianhong Yi, Zensheng Kang, Dickman MB, Daohong Jiang*. 2013. A secretory protein of necrotrophic fungus Sclerotinia sclerotiorum that suppresses host resistance. PLoS One 8(1): e53901.(IF: 3.534); 3. Wei Wei, Wenjun Zhu, Jiasen Cheng, Jiatao Xie, Bo Li, Daohong Jiang, Guoqing Li, Xianhong Yi, Yanping Fu*. 2013. CmPEX6, a gene involved in peroxisome biogenesis, is essential for parasitism and conidiation by the sclerotial parasite Coniothyrium minitans. Applied and Environmental Microbiology 79(12): 3658-66.(IF: 3.952); 4. Hamid MI, Fangyun Zeng, Jiasen Cheng, Daohong Jiang, Yanping Fu*. 2013. Disruption of heat shock factor 1 reduces the formation of conidia and thermotolerance in the mycoparasitic fungus Coniothyrium minitans. Fungal Genetics and Biology 53: 42-9. (IF: 3.262); 2012年; 1. Yang Yu, Daohong Jiang, Jiatao Xie, Jiasen Cheng, Guoqing Li, Xianhong Yi, Yanping Fu*. 2012. Ss-Sl2, a novel cell wall protein with PAN modules, is essential for sclerotial development and cellular integrity of Sclerotinia sclerotiorum. PLoS One 7(4): e34962.(IF: 3.730); 2. Fanyun Zeng, Xiaoyan Gong, Mahammad I Hamid, Yanping Fu, Jiatao Xie, Jiasen Cheng, Guoqing Li, Daohong Jiang*. 2012. The fungal cell wall integrity-associated MAP kinase cascade in the sclerotia mycoparasite fungus Coniothyrium minitans is required for conidiation and mycoparasitism. Fungal Genetics and Biology 49: 347-357.(IF: 3.263); 3. Huiquan Liu, Yanping Fu, Jiatao Xie, Jiasen Cheng, Said A Ghabrial, Guoqing Li, Xianhong Yi, Daohong Jiang*. 2012. Discovery of novel dsRNA viral sequences by in silico cloning and implications for viral diversity, host range and evolution. PLoS One 7(7): e42147. (IF: 3.730); 4. Huiquan Liu, Yanping Fu, Jiatao Xie, Jiasen Cheng, Said A Ghabrial, Guoqing Li, Xianhong Yi, Daohong Jiang*. 2012. Evolutionary genomics of mycovirus-related dsRNA viruses reveals cross-family horizontal gene transfer and evolution of diverse viral lineages. BMC Evolutionary Biology 12: 91. (IF: 3.285); 5. Jiahong Zhou, Yanping Fu, Jiatao Xie, Bo Li, Daohong Jiang, Guoqing Li, Jiasen Cheng*. 2012. Identification of microRNA-like RNAs in a plant pathogenic fungus Sclerotinia sclerotiorum by High-throughput sequencing. Molecular Genetics and Genomics 278(4): 275-282.(IF: 2.881); 2011年; 1. Huiquan Liu, Yanping Fu, Bo Li, Xiao Yu, Jiatao Xie, Jiasen Cheng, Said A Ghabrial, Guoqing Li, Xianhong Yi and Daohong Jiang*. 2011. Widespread horizontal gene transfer from circular single-stranded DNA viruses to eukaryotic genomes. BMC Evolutionary Biology 11: 276.(IF: 3.521); 2. Li Qin, Xiaoyan Gong, Jiatiao Xie, Daohong Jiang, Jiasheng Cheng, Guoqing Li, Junbin Huang, Yanping Fu*. 2011. Phosphoribosylamidotransferase, the first enzyme for purine de novo synthesis, is required for conidiation in the sclerotial mycoparasite Coniothyrium minitans. Fungal Genetics and Biology 48(10): 956-965.(IF: 3.737); 3. Jiatao Xie, Xueqiong Xiao, Yanping Fu, Huiquan Liu, Jiasen Cheng, Said A. Ghabrial, Guoqing Li, Daohong Jiang*. 2011. A novel mycovirus closely related to hypoviruses that infects the plant pathogenic fungus Sclerotinia sclerotiorum. Virology 418, 49-56. (IF: 3.351); 4. Huiquan Liu, Yanping Fu, Daohong Jiang*, Guoqing Li, Jiatao Xie, Jiasen Cheng, Youliang Peng, Said A Ghabrial, and Xianhong Yi. 2011. Widespread Endogenization of Densoviruses and Parvoviruses in Animal and Human Genomes. Journal of Virology 85(19): 9863-9876. (IF: 5.402); 5. Li Qin, Yanping Fu*, Jiatao Xie, Jiasen Cheng, Daohong Jiang, Guoqing Li, and Junbin Huang. 2011. A nested-PCR method for rapid detection of Sclerotinia sclerotiorum on petals of oilseed rape (Brassica napus). Plant Pathology 60: 271-277. (IF: 2.125); 6. Xiao Yu#, Bo Li#, Yanping Fu, Daohong Jiang*, Said A Ghabrial, Guoqing Li, Youliang Peng, Jiatao Xie, Jiasen Cheng, Junbin Huang, and Xianhong Yi. 2011. A geminivirus-related DNA mycovirus that confers hypovirulence to a plant pathogenic fungus. Proc Natl Acad Sci U S A. 107:8387-8392. (IF: 9.681); 2010年及以前; 1. Huiquan Liu, Yanping Fu, Daohong Jiang*, Guoqing Li, Jiatao Xie, Jiasen Cheng, Youliang Peng, Said A Ghabrial, and Xianhong Yi. 2010. Widespread horizontal gene transfer from double-stranded RNA viruses to eukaryotic nuclear genomes. Journal of Virology. 84: 1876-11887. (IF: 5.189); 2. Bo Li, Yanping Fu, Daohong Jiang*, Jiatao Xie, Jiasen Cheng, Guoqing Li, Mahammad Imran Hamid, Xianhong Yi. 2010. Cyclic GMP as a second messenger in the nitric oxide mediated conidiation of the mycoparasite Coniothyrium minitans. Applied and Environmental Microbiology 76: 2830-2836.(IF: 3.778); 3. Weizhang Wang, Jiasen Cheng, Jing Luo J, Shimei Zhuang*. 2008. Abrogation of G2/M arrest sensitizes curcumin-resistant hepatoma cells to apoptosis. FEBS Letters 582(18): 2689-2695. (IF: 3.264); 4. Xingdong Xiong, Jianhong Fang, Fuen Qiu, jing Zhao, Jiasen Cheng, Yunfei Yuan, Shenping Li, Shimei Zhuang*. 2008. A novel functional polymorphism in the Cdc6 promoter is associated with the risk for hepatocellular carcinoma. Mutat Res-FUND MOL M. 643(1-2): 70-4.(IF: 3.198); 5. Dongmin Kuang, Yan Wu, Nini Chen, Jiasen Cheng, Shimei Zhuang, Limin Zheng*. 2007. Tumor-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes. Blood 110(2): 587-595.(IF 10.896); 6. Jiasen Cheng, Dehua Huo, Dongmin Kuang, Jine Yang, Limin Zheng, Shimei Zhuang*. 2007. Human Macrophages Promote the Motility and Invasiveness of Osteopontin- Knockdown Tumor Cells. Cancer Research 67(11): 5141-5147.(IF: 7.672); 7. Jiasen Cheng, Daohong Jiang*, Xianhong Yi, Yanping Fu, Guoqing Li and John M Whipps. 2003. Production, survival and efficacy of Coniothyrium minitans conidia produced in shaken liquid culture. FEMS Microbiology Letters 227 (1): 127-131.(IF: 1.932); 8. Jiasen Cheng, Daohong Jiang*, Yanping Fu, Guoqing Li, Youliang Peng and Said A Ghabrial. 2003. Molecular characterization of a dsRNA totivirus infecting the sclerotial parasite Coniothyrium minitans. Virus Research 93: 41-50.(IF: 1.719)