秦波，男，博士，重慶大學化學化工學院副教授、博士生導師。
基本介紹
- 中文名：秦波
- 畢業院校：四川大學
- 學位/學歷：博士
- 專業方向：有機化學、超分子化學
- 職務：重慶大學化學化工學院博士生導師
人物經歷,研究方向,研究項目,學術成果,論文,專利,
人物經歷
1998-2002 四川大學化學專業學習，獲理學學士學位;
2002-2007 四川大學有機化學專業學習，獲理學博士學位，導師：馮小明院士;
2007-2010 新加坡國立大學化學系做博士後研究，合作導師Prof. Zeng Huaqiang;
2010-2011 新加坡南洋理工大學新加坡膜技術研究中心做博士後研究，合作導師：Prof. Wang Rong和Prof.Zeng Huaqiang;
2013-2014 美國萊斯大學（BioScience Research Collaborative）做博士後研究， 合作導師：Prof. K.C. Nicolaou;
2011-2013 重慶大學化學化工學院 講師;
2013-重慶大學化學化工學院 副教授、博士生導師
研究方向
研究主要從事超分子化學、多肽合成、不對稱合成等領域的科研工作。現已發表SCI收錄論文30餘篇，在國際重要刊物如：J.Am.Chem.Soc.; Chem. Commun.; Org. Lett.; Chem.-Eur. J.; J.Org. Chem.等發表的論文。獲得國家教育部2010年自然科學一等獎。承擔國家自然科學基金2項。
1. 功能性有機分子材料的設計，合成和套用;
2. 不對稱合成方法學，新合成方法與手段，涉及手性醫藥、農藥和具有生理活性化合物的合成研究。
研究項目
1. 軍委科技委創新項目（課題負責人，2017-2018）；
2. 重慶市人工智慧科技創新重大主體專項，重點研發項目（主研，2018.1-2019.12）；
3. 國家自然科學基金(21272293, 課題負責人，2013-2016): 金屬離子識別的螢光感測器可控制備與套用研究；
4. 重慶大學人才引進項目(課題負責人，2012-2015) ；
5. 國家自然科學基金項目（20702033,課題負責人，2008-2010)：新型雙中心催化劑催化酮的不對稱Henry 反應研究；
6. 國家自然科學基金項目（20602025,主研，2007-2009）：手性有機酸鹽催化酮的不對稱腈化反應研究，
學術成果
論文
34. Wu, Q.; Tu, F.; Long, L.;Qin, B.*, Self-Assembly of Intramolecularly Hydrogen-Bonded AmphiphilicDiboronic Acid for Saccharide RecognitionOrg. Biomol. Chem.，2018，submitted.
33.Nicolaou, K. C.*; Cai, Q.; Sun, H. B.; Qin, B.; Zhu, S. G., Total Synthesis of Trioxacarcins DC-45-A1, A, D, C, and C7"-epi-C and Full Structural Assignment of Trioxacarcin C.J.Am. Chem. Soc.2016,138(9), 3118-3124.
32.Nicolaou, K. C.*; Cai, Q.; Qin, B.; Petersen, M. T.; Mikkelsen, R. J. T.; Heretsch, P., Total Synthesis of Trioxacarcin DC-45-A2.Angew. Chem. Int. Edit.2015,54(10), 3074-3078.
31.Fu, H. L.; Chang, H.; Shen, J.; Yu, L.; Qin, B.; Zhang, K.; Zeng, H. Q., An unusual macrocyclization reagent for highly selective one-pot synthesis of strained macrocyclic aromatic hexamers.Chem. Commun.2014,50(27), 3582-3584.
30.Sun, C.; Ren, C. L.; Wei, Y. C.; Qin, B.; Zeng, H. Q., Patterned recognition of amines and ammonium ions by a stimuli-responsive foldamer-based hexameric oligophenol host.Chem. Commun.2013,49(46), 5307-5309.
29.Liu, Y.; Qin, B.; Zeng, H. Q., POCl3-mediated H-bonding-directed one-pot synthesis of macrocyclic pentamers, strained hexamers and highly strained heptamers.Sci. China Chem.2012,55(1), 55-63.
28.Du, Z. Y.; Qin, B.; Sun, C.; Liu, Y.; Zheng, X.; Zhang, K.; Conney, A. H.; Zeng, H. Q., Folding-promoted TBAX-mediated selective demethylation of methoxybenzene-based macrocyclic aromatic pentamers.Org. Biomol. Chem.2012,10(21), 4164-4171.
27.Ren, C. L.; Zhou, F.; Qin, B.; Ye, R. J.; Shen, S.; Su, H. B.; Zeng, H. Q., Crystallographic Realization of the Mathematically Predicted Densest All-Pentagon Packing Lattice by C-5-Symmetric "Sticky" Fluoropentamers.Angew. Chem. In.t Edit2011,50(45), 10612-10615.
26.Qin, B.; Sun, C.; Liu, Y.; Shen, J.; Ye, R. J.; Zhu, J.; Duan, X. F.; Zeng, H. Q., One-Pot Synthesis of Hybrid Macrocyclic Pentamers with Variable Functionalizations around the Periphery.Org. Lett.2011,13(9), 2270-2273.
25.Qin, B.; Shen, S.; Sun, C.; Du, Z. Y.; Zhang, K.; Zeng, H. Q., One-Pot Multimolecular Macrocyclization for the Expedient Synthesis of Macrocyclic Aromatic Pentamers by a Chain Growth Mechanism.Chem-Asian J.2011,6(12), 3298-3305.
24.Qin, B.; Ong, W. Q.; Ye, R. J.; Du, Z. Y.; Chen, X. Y.; Yan, Y.; Zhang, K.; Su, H. B.; Zeng, H. Q., Highly selective one-pot synthesis of H-bonded pentagon-shaped circular aromatic pentamers.Chem. Commun.2011,47(19), 5419-5421.
23.Qin, B.; Jiang, L. Y.; Shen, S.; Sun, C.; Yuan, W. X.; Li, S. F. Y.; Zeng, H. Q., Folding-Promoted TBACI-Mediated Chemo- and Regioselective Demethylations of Methoxybenzene-Based Macrocyclic Pentamers.Org. Lett.2011,13(23), 6212-6215.
22.Yan, Y.; Qin, B.; Ren, C. L.; Chen, X. Y.; Yip, Y. K.; Ye, R. J.; Zhang, D. W.; Su, H. B.; Zeng, H. Q., Synthesis, Structural Investigations, Hydrogen-Deuterium Exchange Studies, and Molecular Modeling of Conformationally Stabilized Aromatic Oligoamides. J. Am. Chem. Soc. 2010,132(16), 5869-5879.
21.Wang, L. W.; Zhang, Q.; Zhou, X.; Liu, X. H.; Lin, L. L.; Qin, B.; Feng, X. M., Asymmetric Conjugate Addition of Nitromethane to Enones Catalyzed by Chiral N,N '-Dioxide Scandium(III) Complexes.Chem-Eur. J.2010,16(26), 7696-7699.
20.Qin, B.; Ren, C. L.; Ye, R. J.; Sun, C.; Chiad, K.; Chen, X. Y.; Li, Z.; Xue, F.; Su, H. B.; Chass, G. A.; Zeng, H. Q., Persistently Folded Circular Aromatic Amide Pentamers Containing Modularly Tunable Cation-Binding Cavities with High Ion Selectivity.J. Am. Chem. Soc.2010,132(28), 9564-9566.
19.Hou, Z. R.; Wang, J.; He, P.; Wang, J.; Qin, B.; Liu, X. H.; Lin, L. L.; Feng, X. M., Highly Enantioselective Insertion of Carbenoids into N-H Bonds Catalyzed by Copper(I) Complexes of Binol Derivatives.Angew. Chem. Int. Edit.2010,49(28), 4763-4766.
18.Chang, L.; Kuang, Y. L.; Qin, B.; Zhou, X.; Liu, X. H.; Lin, L. L.; Feng, X. M., N,N '-Dioxide-Cu(OTf)(2) Complex Catalyzed Highly Enantioselective Amination Reaction of N-Acetyl Enamide.Org. Lett.2010,12(10), 2214-2217.
17.Yan, Y.; Qin, B.; Shu, Y. L.; Chen, X. Y.; Yip, Y. K.; Zhang, D. W.; Su, H. B.; Zeng, H. Q., Helical Organization in Foldable Aromatic Oligoamides by a Continuous Hydrogen-Bonding Network.Org. Lett.2009,11(6), 1201-1204.
16.Qin, B.; Chen, X. Y.; Fang, X.; Shu, Y. Y.; Yip, Y. K.; Yan, Y.; Pan, S. Y.; Ong, W. Q.; Ren, C. L.; Su, H. B.; Zeng, H. Q., Crystallographic Evidence of an Unusual, Pentagon-Shaped Folding Pattern in a Circular Aromatic Pentamer.Org. Lett.2008,10(22), 5127-5130.
15.Zhou, H.; Peng, D.; Qin, B.; Hou, Z. R.; Liu, X. H.; Feng, X. M., Highly enantioselective aza-Henry reaction of N-tosyl imines catalyzed by N,N'-dioxide-Cu(I) complexes.J. Org. Chem.2007,72(26), 10302-10304.
14.Zheng, K.; Qin, B.; Liu, X. H.; Feng, X. M., Highly enantioselective allylation of alpha-ketoesters catalyzed by N,N'-dioxide - In(III) complexes.J. Org. Chem.2007,72(22), 8478-8483.
13.Zhao, H. T.; Qin, B.; Liu, X. H.; Feng, X. M., Enantioselective trifluoromethylation of aromatic aldehydes catalyzed by combinatorial catalysts.Tetrahedron2007,63(29), 6822-6826.
12.Qin, B.; Xiao, X.; Liu, X. H.; Huang, J. L.; Wen, Y. H.; Feng, X. M., Highly enantioselective henry (nitroaldol) reaction of aldehydes and alpha-ketoesters catalyzed by N,N '-Dioxide-Copper(I) complexes.J. Org. Chem.2007,72(24), 9323-9328.
11.Qin, B.; Liu, X. H.; Shi, J.; Zheng, K.; Zhao, H. T.; Feng, X. M., Enantioselective cyanosilylation of alpha,alpha-dialkoxy ketones catalyzed by proline-derived in-situ-prepared N-oxide as bifunctional organocatalyst.J. Org. Chem.2007,72(7), 2374-2378.
10.Huang, J. L.; Liu, X. H.; Wen, Y. H.; Qin, B.; Feng, X. M., Enantioselective strecker reaction of phosphinoyl ketoimines catalyzed by in situ prepared chiral N,N '-dioxides.J. Org. Chem.2007,72(1), 204-208.
9.Lin, L. L.; Fan, Q.; Qin, B.; Feng, X. M., Highly enantio- and diastereoselective brassard type hetero-Diels-Alder approach to 5-methyl-containing alpha,beta-unsaturated delta-lactones.J. Org. Chem.2006,71(11), 4141-4146.
8.Wen, Y. H.; Huang, X.; Huang, J. L.; Xiong, Y.; Qin, B.; Feng, X. M., Asymmetric cyanosilylation of aldehydes catalyzed by novel organo-catalysts.Synlett2005,(16), 2445-2448.
7.Liu, X. H.; Qin, B.; Zhou, X.; He, B.; Feng, X. M., Catalytic asymmetric cyanosilylation of ketones by a chiral amino acid salt.J. Am. Chem. Soc.2005,127(35), 12224-12225.
6.Li, Y.; He, B.; Qin, B.; Feng, X. M.; Zhang, G. L., Highly enantioselective cyanosilylation of aldehydes catalyzed by novel beta-amino alcohol-titanium complexes.J. Org. Chem.2004,69(23), 7910-7913.
5.Chen, F. X.; Zhou, H.; Liu, X. H.; Qin, B.; Feng, X. M.; Zhang, G. L.; Jiang, Y. Z., Enantioselective cyanosilylation of ketones by a catalytic double-activation method with an aluminium complex and an N-oxide.Chem-Eur. J.2004,10(19), 4790-4797.
4.Chen, F. X.; Qin, B.; Feng, X. M.; Zhang, G. L.; Jiang, Y. Z., Enantioselective cyanosilylation of ketones catalyzed by double-activation catalysts with N-oxides.Tetrahedron2004,60(46), 10449-10460.
3. Chen, F. X.; Liu, X. H.; Qin, B.; Zhou, H.; Feng, X. M.; Zhang, G. L., Highly efficient double-activation catalysts for the synthesis of ketone cyanohydrins.Synthesis2004,(14), 2266-2272.
2.Chen, F. X.; Feng, X. M.; Qin, B.; Zhang, G. L.; Jiang, Y. Z., Highly efficient silylcyanation of ketones by a catalytic double activation method using lewis acid and N-oxide catalysts.Synlett2003,(4), 558-560.
1.Chen, F. X.; Feng, X. M.; Qin, B.; Zhang, G. L.; Jiang, Y. Z., Enantioselective cyanosilylation of ketones by a catalytic double-activation method employing chiral Lewis acid and achiral N-oxide catalysts.Org. Lett. 2003,5(6), 949-952.
專利
1. 一種芳香摺疊體六元環的合成方法 -201510239231.2;104876940B(授權)
2. 一種專一識別銫離子的新型有機芳香大環的製備與套用 -201610031460.X（申請）
3. 一種溫和條件下脫除酚羥基甲基保護基的方法 -201610114850.3（申請）
