瑞穗信託銀行（Mizuho Trust & Banking，TYO: 8404）是瑞穗金融集團的四大金融機構之一（其他包括：瑞穗銀行（Mizuho Bank）、瑞穗實業銀行（Mizuho Corporate Bank）和瑞穗證券公司(Mizuho Securities)）。
瑞穗信託銀行主要從事與資產管理相關的多種託管業務，包括投資信託、證券信託、養老金信託及股票過戶代理。瑞穗信託銀行過去只可以經營長期金融業務，現在也可以經營個人銀行業務和房地產業務，如土地信託、不動產買賣中介、不動產評估、住宅銷售服務等。
Mizuho Trust & Banking Co., Ltd. (みずほ信託銀行株式會社) is the trust banking arm of Mizuho Financial Group, the second-biggest Japanese financial services company. The bank's headquarters are inYAESU, Chūō, Tokyo.
One of the bank's predecessor Yasuda Trust & Banking Co., Ltd. traces its history as far back as the old Yasuda zaibatsu. It was founded in 1925 as Kyosai Trust.
In 1996, Yasuda Trust become a subsidiary of the Fuji Bank after running into problems with earnings and credit quality.
The merger of the Dai-Ichi Kangyo Bank, Fuji Bank and the Industrial Bank of Japan in 2000 was followed by the merger of their respective trust banking subsidiaries, creating Mizuho Trust & Banking Co.
