王爽，男，博士學位，現任杭州鍩崴信息科技有限公司董事長，四川大學華西醫院特聘教授，同濟大學附屬醫院客座教授。2018年中組部引進“海外青年高層次人才”。曾任美國加州大學聖地亞哥分校（UCSD）醫學院生物醫學信息系教授。國際同態加密協會創始委員。
基本介紹
- 中文名：王爽
- 國籍：中國
- 民族：漢族
- 主要成就：全球首次提出安全聯邦學習框架並套用在國家級醫療健康網路，聯合創辦國際頂級賽事iDASH 隱私保護計算比賽
- 學位/學歷：博士
- 職務：鍩崴科技創始人、董事長
- 研究領域：隱私保護計算，數據安全，生物醫療信息，機器學習，高性能計算等
- 職稱：同濟大學附屬醫院客座教授、四川大學華西醫院特聘教授
人物簡介,主要貢獻,人物榮譽,科研論文,國際期刊,
人物簡介
王爽博士現任鍩崴科技創始人、董事長，同濟大學附屬醫院客座教授、四川華西醫院特聘教授，2018年中組部引進的“海外青年高層次人才”，曾任美國加州大學聖地亞哥分校UCSD醫學院生物醫學信息系教授，國際同態加密協會創始會員，電氣和電子工程師協會IEEE高級會員，美國醫療信息協會（AMIA）會員。其主要研究方向包含數據隱私與安全，生物醫療信息，大數據分析，機器學習，高性能計算等。
先後發表國際學術著作100餘篇，2012年發表全球第1篇聯邦學習論文，解決醫療領域多中心合作難題，擁有多項隱私計算領域專利。
擔任領域內旗艦雜誌Nature Biotechnology,Nature Communication等雜誌的審稿人和 PLOS Genetics 客座編輯, BMC Medical Genomics 特刊主編。
參與了包含國家科技部、公安部、海南省科技廳、浙江省科技廳等“十四五”國家級及省部級重大研發項目。曾主持美國國立衛生研究院（NIH）、英特爾（Intel）創新合作項目、英偉達(NVIDIA)高性能並行計算、Amazon雲計算等項目。
國際頂級賽事iDASH 隱私保護計算比賽創辦人，被Nature news和GenomeWeb多次報導。領導開發的獨特的基於SGX硬體技術的大規模基因安全數據分析模型，2016年獲得了Intel的傑出貢獻獎。
與生物信息AI產業專家鄭灝博士共同創立杭州鍩崴信息科技有限公司。
主要貢獻
2012年，開創性地提出安全聯邦學習底層框架並套用在大規模醫療線上學習；
2014年，聯合創辦全球隱私保護計算大賽（iDASH）
2015年，推動實現全球首次將同態加密技術套用到聯邦式多中心罕見病研究中；
2016年，推動實現全球首次基於可信執行環境技術進行跨國且聯邦式的多中心罕見病研究；
2017年，牽頭與美國國家標準與技術研究院（National Institute of Standards and Technology）和國際標準化組織ISO及IBM、微軟等國際大廠聯合成立了國際同態加密標準委員會，並且制定了同態加密套用標準；
2018年，創新性提出支持不同隱私保護技術的融合性解決方案；
2019年，帶領團隊完成全國首例帶隱私保護的多中心全基因組分析；
2021年，帶領團隊打造大數據安全可信流動的基礎設施，支持雲原生、彈性擴張，支持隱私計算服務編排；同時打造癌症和罕見病網路
人物榮譽
2016年，榮獲英特爾(Intel)SGX安全基因計算平台傑出貢獻獎；
2018年，成為中組部引進的“海外青年高層次人才”
2020年，參與項目榮獲“2019年度上海科技進步一等獎”；
2022年1月，榮膺“隱私計算十大人物”；
2022年3月，榮膺“2021年度隱私計算突出貢獻人物”
2022年7月，獲評《麻省理工科技評論》中國2022年隱私計算科技創新人物
科研論文
書本和章節
1、S. Wang*, X. Jiang*, D. Fox, L. Ohno-Machado, “Preserving Genome Privacy in Research Studies”, book chapter in Medical Data Privacy Handbook, Eds. G. Loukides and A. Gkoulalas-Divanis, Springer 2015
2、N. Mohammed, S. Wang, R. Chen, X. Jiang, “Private Genome Data Dissemination”, book chapter in Medical Data Privacy Handbook, Eds. G. Loukides and A. Gkoulalas-Divanis, Springer 2015
3、S. Wang, Y. Fang, S. Cheng, “Understanding distributed source coding from theory to practice”, Wiley, 2016
4、W. Dai, S. Wang, H. Xiong, X. Jiang, “ Privacy Preserving Federated Big Data Analysis” book chapter in Guide to Big Data Applications, S. Srinivasan. (Eds), Springer-Verlag 2017
國際期刊
1、X. Wang, S. Wang, Q. Pan, Y. Liu, M. He, “Breathing Modes in Dusty Plasma”, Plasma Science & Technolo-gy, 5(4): 1901, 2003.
2、M. He, Q. Pan, S. Wang, “Final State of Ecosystem Containing Grass, Sheep and Wolves With Aging”, Inter-national Journal of Modern Physics C, 16(1): 177-190, 2005.
3、M. He, S. Wang, “A Study of Immunity Based on Penna Aging Model”, International Journal of Modern Phys-ics C,17(4): 479-492, 2006
4、S.Wang, L.Cui, S.Cheng, Y.Zhai, M.Yeary and Q.Wu, “Noise Adaptive LDPC Decoding Using Particle filtering”, IEEE Transactions on Communications, 59 (4): 913-916, 2011.
5、L. Cui, S. Wang, S. Cheng and M. Yeary “Adaptive Binary Slepian-Wolf Decoding Using Particle Based Be-lief Propagation”, IEEE Transactions on Communications, 59 (9): 2337-2342, 2011
6、S. Wang, L. Cui, D. Liu, R. Huck, P. Verma, James Jr. Sluss and S. Cheng, “Vehicle Identification via Sparse Representation”, IEEE Transactions on Intelligent Transportation Systems, 13(2):955-962, 2012.
7、S. Wang, L. Cui, S. Cheng, L. Stankovic, V. Stankovic “Adaptive Correlation Estimation With Particle Filtering For Distributed Video Coding”, IEEE Transactions on Circuits and Systems for Video Technology, 22 (5): 649-658, 2012.
8、L. Cui, S. Wang, S. Cheng, “Adaptive Slepian-Wolf Decoding Based on Expectation Propagation”, IEEE Communications Letters, 16 (2): 252-255, 2012.
9、S. Wang, L. Cui, L. Stankovic, and V. Stankovic, S. Cheng, “Onboard Low-Complexity Compression of Solar Stereo Images”, IEEE Transactions on Image Processing, 21(6): 3114-3118 (2012). PMID: 22345534
10、S. Wang, L. Cui, J. Que, Dae-Hyun Choi, X. Jiang, S. Cheng and L. Xie “A Randomized Response Model For Privacy Preserving Smart Metering”, IEEE Transactions on Smart Grid, 3(3): 1317-1324, 2012. PMID: 23243488
11、V. Stankovic , L. Stankovic , S. Wang, S. Cheng “Distributed Compression for Condition Monitoring of Wind Farms”, IEEE Transactions on Sustainable Energy, 4 (1):174-181, 2013.
12、X. Jiang, A. Menon, S. Wang, J. Kim, and L. Ohno-Machado “Doubly Optimized Calibrated Support Vector Machine (DOC-SVM): An Algorithm for Joint Optimization of Discrimination and Calibration”, PLoS ONE, 7(11):e48823, 2012. PMID: 23139819
13、X. Jiang, Z. Ji, S. Wang, N. Mohammed, S. Cheng, and L. Ohno-Machado “Differential-Private Data Publishing Through Component Analysis”, Transaction on Data Privacy, 6 (1): 19-34, 2013. PMID: 24409205
14、S. Wang, X. Jiang, Y. Wu, L. Cui, S. Cheng, L. Ohno-Machado, “EXpectation Propagation LOgistic REgRession (EXPLORER): Distributed Privacy-Preserving Online Model Learning”, Journal of Biomedical Informatics, 46 (3): 480-496, 2013. PMID: 23562651
15、W. Jiang, P. Li, S. Wang, Y. Wu, M. Xue, and L. Ohno-Machado, X. Jiang, “WebGLORE: A Webservice for Grid LOgistic REgression”, Bioinformatics, 29(24): 3238-3240, 2013. PMID: 24072732
16、X. Jiang, K. Tse, S. Wang, S. Doan, H. Kim, L. Ohno-Machado, “Recent Trends in Biomedical Informatics: A Study Based on JAMIA Articles”, Journal of the American Medical Informatics Association, 20: e198-e205, 2013. PMID: 24214018
17、P. Li, S. Wang, J. Kim, H. Xiong, L. Ohno-Machado, X. Jiang, “DNA-COMPACT: DNA COMpression Based on a Pattern-Aware Contextual Modeling Technique”, PlOS one, 8(11): e80377, 2013. PMID: 24282536
18、P. Li, X. Jiang, S. Wang, J. Kim, H. Xiong, L. Ohno-Machado, “HUGO: Hierarchical mUlti-reference Genome cOmpression for Aligned Reads”, Journal of the American Medical Informatics Association, 21(2): 363-373, 2014. PMID: 24368726
19、N. Deligiannis, A. Munteanu, S. Wang, S. Cheng, P. Schelkens, “Maximum Likelihood Laplacian Correlation Channel Estimation in Layered Wyner-Ziv Coding”, Signal Processing IEEE Transactions on, 62(4): 892-904, 2014.
20、Z. Ji, X. Jiang, S. Wang, L. Xiong, and L. Ohno-Machado. “Differentially Private Distributed Logistic Regression Using Private and Public Data”, BMC Medical Genomics, 7 (S1): S14, 2014. PMID: 25079786
21、S. Wang, J. Kim, X. Jiang, S. Brunner, L. Ohno-Machado, “GAMUT: GPU Accelerated MicroRNA Analysis to Uncover Target Genes Through CUDA-miRanda”, BMC Medical Genomics, 7(S1): S9, 2014. PMID: 25077821
22、J. Kim, E. Levy, A. Ferbrache, P. Stepanowsky, C. Farcas, S. Wang, S. Brunner, T. Bath, Y. Wu, and L. Ohno-Machado, “MAGI: a Node.js Web Service for Fast MicroRNA-Seq Analysis In a GPU Infrastructure”, Bioinformatics, 30(9): 2826-7, 2014. PMID: 24907367
23、S. Wang, X. Jiang, F. Chen, L. Cui, and S. Cheng, “Streamlined Genome Sequence Compression Using Distributed Source Coding”, Cancer Informatics, 13 (S1): 123-31, 2014. PMID: 25520552
24、S. Wang, X. Jiang, N. Mohammed, R. Chen, “Differentially Private Genome Data Dissemination Through Top-Down Specialization”, BMC Medical Informatics and Decision Making, 14 (S1): S2, 2014. PMID: 25521306
25、X. Jiang, Y. Zhao, X. Wang, B. Malin, S. Wang, L. Ohno-Machado, H. Tang, “A Community Assessment of Privacy Preserving Techniques On Human Genome Data”, BMC Medical Informatics and Decision Making, 14 (S1): S1, 2014. PMID: 25521230
26、A. Roozgard, N. Barzigar, S. Wang, X. Jiang, and Samuel Cheng, "Empirical Transition Probability Indexing Sparse-Coding Belief Propagation (ETPI-SCoBeP) Genome Sequence Alignment" Cancer Informatics 13 (S1): 159-65, 2015 PMID: 25983537
27、Y. Wu, X. Jiang, S. Wang, W. Jiang, P. Li, L. Ohno-Machado, “Grid Multi-Category Response Logistic Models”, BMC Medical Informatics and Decision Making, 15:10, 2015. PMID: 25886151
28、C. Lu*, S. Wang*, Y. Wu, Z. Ji, L. Xiong, X. Jiang, L. Ohno-Machado, “WebDISCO: a Webservice for DIStributed COx model learning without patient-level data sharing”, Journal of the American Medical Informatics Association 2015 Nov; 22(6):1212-9 PMID: 26159465
29、D. Han*, S. Wang*, C. Jiang, X. Jiang, H. Kim, J. Sun, L. Ohno-Machado, "Trends in biomedical informatics: Automated topic analysis of JAMIA articles" JAMIA, 2015 Nov;22(6):1153-63 PMID: 26555018
30、Y. Zhang, W. Dai, X. Jiang, H. Xiong, S. Wang, "FORESEE: Fully Outsourced secuRe gEnome Study basEd on homomorphic Encryption" BMC Medical Informatics and Decision Making, 2015; 15:S5 PMID: 26733391
31、S. Constable, Y. Tang, S. Wang, X. Jiang, S. Chapin, "Privacy-Preserving GWAS Analysis on Federated Genomic Datasets" by BMC Medical Informatics and Decision Making, 2015; 15:S2 PMID: 26733045
32、S. Wang*, Y. Zhang*, W. Dai, K. Lauter, M. Kim, Y. Tang, H. Xiong, X. Jiang "HEALER: Homomorphic computation of ExAct Logistic rEgRes-sion for secure rare disease variants analysis in GWAS" Bioinformatics, 2016 Jan 15; 32(2):211-8 PMID: 26446135
33、Y. Li, X. Jiang, S. Wang, H. Xiong, L. Ohno-Machado, "VERTIcal Grid lOgistic regression (VERTI-GO)" Journal of the American Medical Informatics Association 2016 May;23(3):570-9 PMID: 26554428
34、L. Yang*, S. Wang*, X. Jiang, S. Cheng, H. Kim. “PATTERN: Pain Assessment for paTients who can’t TEll using Restricted Boltzmann machine”, BMC Medical Informatics and Decision Making. 2016 Jul 25;16(3):189.
35、H. Shi, C. Jiang, W. Dai, X. Jiang, Y. Tang, L. Ohno-Machado, S. Wang “Secure Multi-pArty Computation Grid LOgistic REgression (SMAC-GLORE)” BMC Medical Informatics and Decision Making. 2016 Jul 25;16(3):175. PMID: 27454168
36、S. Wang, X. Jiang, S. Singh, R. Marmor, L. Bonomi, D. Fox, M. Dow, L. Ohno-Machado, “Genome privacy: challenges, technical approaches to mitigate risk, and ethical considerations in the United States”, Annals of The New York Academy of Sciences, 2017, 1387(1):73-83 PMID: 27681358
37、S. Wang, L. Bonomi, W. Dai, F. Chen, C. Cheung, C. S. Bloss, S. Cheng, X. Jiang, “Big Data Privacy in Biomedical Research”, IEEE Transactions on Big Data, 2016, September 13. 296 - 308
38、H. Tang*, X. Jiang*, X. Wang*, S. Wang*, H. Sofia, D. Fox, K. Lauter, B. Malin, A. Telenti, L. Xiong, L. Ohno-Machado, “ Protecting Genomic Data Analytics in the Cloud: State of the Art and Opportunities”, BMC Medical Genomics, 2016 9(1):63 PMID: 27733153
39、W. Farhan, Z. Wang, Y. Huang, S. Wang, F. Wang, X. Jiang, “ A Predictive Model for Medical Events Based on Contextual Embedding of Temporal Sequences”, JMIR Medical Informatics, 2016 Nov. 25;4(4):e39. PMID: 27888170
40、PS. Dulai, S. Singh, X. Jiang, F. Peerani, N. Narula, K. Chaudrey, D. Whitehead, D. Hudesman, D. Lukin, A. Swaminath, E. Shmidt. S. Wang, B. Boland, J. Chang, S. Kane, C. Siegel, E. Loftus, W. Sandborn, B. Sands, J. Colombel. “The Real-World Effectiveness and Safety of Vedolizumab for Moderate–Severe Crohn’s Disease: Results From the US VICTORY Consortium” The American journal of gastroenterology 2016 August, 111:1147-1155. PMID: 27296941
41、JL. Raisaro, F. Tramèr, Z. Ji, D. Bu, Y. Zhao, K. Carey, D. Lloyd, H. Sofia , D. Baker, P. Flicek, S. Shringarpure, C. Bustamante, S. Wang, X. Jiang, L. Ohno-Machado, H. Tang, X. Wang, J. Hubaux, “Addressing Beacon Re-Identification Attacks: Quantification and Mitigation of Privacy Risks”, Journal of the American Medical Informatics Association. 2017 Jul; 24(4):799-805, PMID: 28339683
42、F. Chen*, S. Wang*, X. Jiang, S. Ding, Y. Lu, J. Kim, S. Sahinalp, C. Shimizu, J. Burns, V. Wright, E. Png, M. Hibberd, D. Lloyd, H. Yang, A. Telenti, C. Bloss, D. Fox, K. Lauter, L. Ohno-Machado “PRINCESS: Pri-vacy-protecting Rare disease International Network Collaboration via Encryption through Software guard extensionS”, Bioinformatics. 2017, 33 (6): 871-878 PMID: 28065902
43、R. Miotto, F. Wang, S. Wang, X. Jiang, and J. Dudley “Deep Learning for Healthcare: Review, Opportunities and Challenges”, Briefings in Bioinformatics In press, 2017 May, 1-11，PMID:28481991
44、R. Marmor, W. Dai, X. Jiang, S. Wang, S. Blair, J. Huh, “Increase in Contralateral Prophylactic Mastectomy Conversation Online Unrelated to Decision-Making”, Journal of Surgical Research, 2017 Oct; 218:253-60, PMID: 28985858
45、F. Chen, C. Wang, W. Dai, X. Jiang, N. Mohammed, M. Aziz, M. Sadat, C. Sahinalp, K. Lauter, S. Wang “PRESAGE: PRivacy-preserving gEnetic testing via SoftwAre Guard Extension”, BMC Medical Genomics, 2017 Jul 26;10(Suppl 2):48, PMID: 28786365
46、M. Aziz, M. Sadat, D. Alhadidi, S. Wang, X. Jiang, C. Brown, N. Mohammed, “Privacy Preserving Techniques of Genomic Data A Survey”, Briefings in Bioinformatics, In press, 2017 Nov, 887-895 ，PMID: 29121240 .
47、S. Wang, X. Jiang, H. Tang, X. Wang, D. Bu, K. Carey, S. OM Dyke, D. Fox, C. Jiang, K. Lauter, B. Malin, H. Sofia, A. Telenti, L. Wang, W. Wang, and Lucila Ohno-Machado, “ A community effort to protect genomic data sharIng, collaboration and outsourcing”, NPJ Genomic Medicine, In press, 2017 Oct, 33，PMID: 29263842
48、M. Wang, Z. Ji, S. Wang, J. Kim, H. Yang, X. Jiang, L. Ohno-Machado “Mechanisms to Protect the Privacy of Families when Using the Transmission Disequilibrium Test in Genome-Wide Association Studies” Bioinformatics 2017 Dec, 3716-3725，PMID: 29036461
49、M. Wang, Z. Ji, S. Wang, H. Kim, X. Jiang “Selecting Optimal Subset to release under Differentially Private M-estimators from Hybrid Datasets”, Transactions on Knowledge and Data Engineering, 2017, 30 (3): 573 – 584.
50、M. Sadat, X. Jiang, M. Aziz, S. Wang, N. Mohammed, “Secure and Efficient Regression Analysis using a Hybrid Cryptographic Framework”, JMIR Medical Informatics, 2018, 6(1): e14, PMID: 29506966
51、F. Chen*, X. Jiang*, S. Wang*, L. Schilling, D. Meeker, T. Ong, M. Matheny, J. Doctor, L. Ohno-Machado, J. Vaidya, “Perfectly Secure and Efficient Two-party Electronic Health Record Linkage”, IEEE Internet Compu-ting, Jan, 2018, 22 (2) PMID: 29867290
52、J. Lee, J. Sun, F. Wang, S. Wang, Y. Chen, C. Jun, X. Jiang “Privacy-Preserving Patient Similarity Learning in a Federated Environment”, JMIR Medical Informatics, Jan 2018, 6 (2) PMID: 29653917.
53、M. Kim, Y. Song, S. Wang, Y. Xia, X. Jiang, “Secure Logistic Regression based on Homomorphic Encryption”, JMIR Medical Informatics, Jan 2018, 6 (2) PMID: 29666041.
54、Y. Huang, J. Lee, S. Wang, J. Sun, H. Liu, X. Jiang, “Privacy-Preserving Harmonization of Contextual Embeddings From Different Sources”, JMIR Medical Informatics, Mar 2018, 6 (2) PMID: 29769172
55、A. Arellano, W. Dai, S. Wang, X. Jiang, L. Ohno-Machado, “Privacy Policy and Technology in Biomedical Data Science”, Annu. Rev. Biomed, 2018, 1: 115-129
56、S. Dyke, et. al. “Registered access: authorizing data access”, European Journal of Human Genetics, 2018, 26, 1721–1731 PMID: 30069064.
57、Y. Jiang, J. Hamer, C. Wang, X. Jiang, M. Kim, Y. Song, Y. Xia, N. Mohammed, M. Sadat, S. Wang, “SecureLR: Secure Logistic Regression Model via a Hybrid Cryptographic Protocol”, IEEE Transactions on Computational Biology and Bioinformatics, 2019, 16 (1).
58、M. Sadat, M. Aziz, N. Mohammed, F. Chen, X. Jiang, S. Wang, “SAFETY: Secure gwAs in Federated Environment Through a hYbrid solution”, IEEE Transactions on Computational Biology and Bioinformatics, 2019, 16 (1).
59、H. Zheng, X. Wu, J. Yin, S. Wang, Z. Li ,C. You, “Clinical applications of liquid biopsies for early lung can-cer detection”, American Journal of Cancer Research, 2019; 9(12): 2567–2579
60、Z. Dou, C. Wang, J. Deng, H. Zheng, K. Xie, B. Shen, S. Wang. “Challenges, strategies and technologies in biomedical big data privacy and security protection” Chinese Journal of Medical Libaray and Information Science. 11-15，2019
61、M. Gong*, S. Wang*, L. Wang, C. Liu, J. Wang, Q. Guo, H. Zheng, K. Xie, C. Wang, Z. Hui, “Evaluation of Privacy Risks of Patients' Data in China: Case Study”, JMIR Med Inform. 2020 Feb 5;8(2):e13046
62、Z. Dou, F. Chen, J. Deng, R. Chen, H. Zheng, Q. Sun, K. Xie, B. Shen, S. Wang, “Methods and Applications of Federated Learning in Biomedical Big Data Privacy Protection”, Journal of Medical Informatics, 2-10，2020
63、M. Gong, L. Li, S. Xin, Y. Yue, S. Wang, Z. Hong“Cloud-Based System for Effective Surveillance and Control of COVID-19: Useful Experiences From Hubei, China”, J Med Internet Res. e18948，2020 Apr 9
64、G. He, S. Wang, Y. Xiao, D.X. Deng, H. Zheng, “A New Method for Genomic Rearrangement Detection using Third Generation Sequencing Data”, Transactions on Computational Science & Computational Intelligence, 2020
65、R. Zhu, C. Jiang, X. Wang, S. Wang, H. Zheng, H. Tang “Privacy-preserving construction of generalized linear mixed model for biomedical computation”, Bioinformatics 36 (S1), i128-i135, 2020
66、J. Doctor, J. Vaidya, X. Jiang, S. Wang, L. Schilling, T. Ong, M. Matheny, L. Ohno-Machado, D. Meeker, “Efficient Determination of Equivalence for Encrypted Data”, Computers & Security, 97, 101939, 2020
67、X. Wu, H. Zheng, Z. Dou, F. Chen, J. Deng, X. Chen, S. Xu, G. Gao, M. Li, Z. Wang, Y. Xiao, K. Xie, S. Wang, H. Xu, “A Novel Privacy-Preserving Federated Genome-wide Association Study Framework and its Application in Identifying Potential Risk Variants in Ankylosing Spondylitis”, Briefing in Bioinformatics, 2 (3), bbaa090, 2021
68、R. Chen, Y. Zhang, Z. Dou, F. Chen, K. Xie, S. Wang, “Data Sharing and Privacy in Pharmaceutical Studies”, Current Pharmaceutical Design, 27 (7), 911-918, 2021
