王永志,博士,主任醫師,博士生導師,首都醫科大學附屬北京天壇醫院神經外科醫師,脊髓脊柱外科行政副主任。
臨床擅長:椎管腫瘤、脊髓栓系、寰樞椎脫位、頸椎間盤突出、腰椎管狹窄、小腦扁桃體下疝及脊髓空洞症等的微創外科治療,尤其擅長脊髓膠質瘤手術及基於分子分型的綜合治療。
基本介紹
主要研究方向
社會任職
重要獎項
人物經歷
代表論文
- Yong-Zhi Wang, Yao-Wu Zhang, Wei-Hao Liu, Rui-Chao Chai, Ren Cao, Bo Wang,Song-Yuan An, Wen-Ju Jiang, Yu-Lun Xu, Jun Yang, Wen-Qing Jia*. Spinal corddiffuse midline gliomas with H3 K27M-mutant: clinicopathological features andprognosis [J]. Neurosurgery. 2021,9:6996–7006.
- Wang Y, Li S, Chen L,You G, Bao Z, Yan W, Shi Z, Chen Y, Yao K, Kang C*, Jiang T*. Glioblastomawith oligodendroglioma component: distinct clinical behavior, geneticalterations and outcome. Neuro-Oncoloy.2012, 14(4):518-525.
- Lin Y, Chen Y, Wang Y, Yang J, Zhu VF, Cui X, Chen L, Yan W, Jiang T, Hergenroeder GW,Fletcher SA, Tandon N, Zhu JJ, and Li M*.ZIP4 is a Novel Molecular Marker for Glioma. Neuro- Oncology. 2013, 15(8):1008-1016.[Co-first Author].
- Wang Y,Jiang T*. Understanding High GradeGlioma: Molecular Mechanism, Therapy and Comprehensive Management. Cancer Letters. 2013, 331(2):139-146.
- Zhang Q, Cheng S, Wang Y,Wang M, Lu Y, Wen Z, Ge Y, Ma Q,Chen Y, Zhang Y, Cao R, Li M, Liu W, Wang B, Wu Q*,Jia W*, Wang X*. Interrogation of the microenvironmentallandscape in spinal ependymomas reveals dual functions of tumor-associatedmacrophages. Nature Communications. 2021,12: 6867. doi:org/10.1038/s41467-021-27018-9.
- Rui-Chao Chai, Yu-Qing Liu,Ke-Nan Zhang, Fan Wu, Zheng Zhao, Kuan-Yu Wang, Tao Jiang, Yong-Zhi Wang*. A novelanalytical model of MGMT methylation pyrosequencing offers improved predictiveperformance in patients with gliomas. ModernPathology. 2019, 32(1):4-15.
- Rui-Chao Chai, Yu-Zhou Chang, XinChang, Bo Pang, Song Yuan An, Ke-Nan Zhang, Yuan-Hao Chang, Tao Jiang*, Yong-ZhiWang*. YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediatedm6A modification to activate NF-κB and promote the malignant progression ofglioma. J Hematol Oncol, 2021, 14(1):109. doi:10.1186/s13045-021-01124-z.
- Rui-Chao Chai, Yao-Wu Zhang, Yu-Qing Liu, Yu-Zhou Chang,BoPang, Tao Jiang, Wen-Qing Jia*,Yong-Zhi Wang*. The molecularcharacteristics of spinal cord gliomas with or without H3 K27M mutation.Acta Neuropathol Commun. 2020, 8 (1):40. doi: 10.1186/s40478-020-00913-w
- Rui-Chao Chai, Yi-Ming Li,Ke-Nan Zhang, Yu-Qing Liu, Zheng Zhao,Yu-Zhou Chang, Yuan-Hao Chang, Guan-ZhangLi, Kuan-Yu Wang, Fan Wu*, Yong-Zhi Wang*. RNA processing genes characterize RNA splicing and furtherstratify lower-grade glioma. JCI Insight. 2019,4(17):e130591.
- Rui-Chao Chai, Ke-Nan Zhang,Yu-Zhou Chang, Fan Wu, Yu-Qing Liu, Zheng Zhao, Kuan-Yu Wang, Yuan-Hao Chang,Tao Jiang*,Yong-Zhi Wang*. Systematicallycharacterize the clinical and biological significances of 1p19q genes in 1p/19qnon-codeletion glioma. Carcinogenesis. 2019, 40(10):1229-1239