教育背景
1989.09-1995.07 第三軍醫大學臨床醫學系(六年制) 本科
1996.09-1999.07 第三軍醫大學 醫學碩士
2003.09-2006.07 第三軍醫大學 醫學博士
2005.05-2009.04 澳大利亞Flinders大學神經科學中心 PhD(博士)
學術任職
中國老年醫學會認知障礙分會 副會長
中華醫學會神經病學分會第六屆青年委員會 副主任委員
中華醫學會神經病學分會痴呆與認知障礙學組 委員
中國醫師協會神經病學分會痴呆學組 委員
全軍神經病學分會青年委員會 副主任委員
全軍認知障礙相關疾病學組 常委
重慶市中西醫結合學會神經病學分會 主任委員
重慶市神經科學會 理事
Journal of Alzheimers Disease(SCI,美國) 編委
Neurotoxicity Research(SCI,美國) 編委
American Journal of Immunology (美國) 編委
《中國醫學前沿雜誌》、《重慶醫學》、《解放軍醫藥》 編委
代表性論文
1 Yao XQ, Jiao SS, Saadipour K, Zeng F, Wang QH,
Zhu C,
Shen LL,Zeng GH,
Liang CR, Wang J,Liu YH,
Hou HT,
Xu X,
Su YP,
Fan XT, Xiao HL, Lue LF,Zeng YQ, Giunta B, Zhong JH,
Walker DG,
Zhou HD,
Tan J,
Zhou XF*,
Wang YJ*. p75NTR ectodomain is a physiological neuroprotective molecule against amyloid-beta toxicity in the brain of Alzheimer’s disease.
Mol Psychiatry. 2015; 20(11):1301-1310.(封面文章,並配專家述評)
2 Xiang Y, Bu XL, Liu YH, Zhu C, Shen LL, Jiao SS, Zhu XY, Giunta B, Tan J, Song W, Zhou HD, Zhou XF, Wang YJ*. Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer’s disease. Acta Neuropathologica. 2015;130(4):487-499.(揭示人體天然Aβ外周清除能力,受專家述評)
3 Jiao SS, Yao XQ, Liu YH, Wang QH, Zeng F, Lu JJ, Liu J, Zhu C, Shen LL, Liu CH, Wang YR, Zeng GH, Parikh A., Chen J, Liang CR, Xiang Y, Bu XL, Deng J, Li J, Xu J, Zeng YQ, Xu X, Xu HW, Zhong JH, Zhou HD, Zhou XF*, Wang YJ*. Edaravone alleviates Alzheimer’s disease-type pathologies and cognitive deficits. Proc Natl Acad Sci U S A. 2015; 112(16):5225-5230.
4 Wang YJ. Alzheimer disease:Lessons from immunotherapy for Alzheimer disease. Nat Rev Neurol. 2014;10(4):188-189.IF=15.358 cite 11(特邀評論,提出AD“分期綜合干預”觀點)5 Liu YH, Giunta B, Zhou HD, Tan J, Wang YJ. Immunotherapy for Alzheimer disease: the challenge of adverse effects. Nat Rev Neurol. 2012;8(8):465-469.(特邀綜述,提出AD防治“Aβ外周清除”策略)6 Li J,Wang YJ,Zhang M,Xu ZQ,Gao CY, Fang CQ, Yan JC, Zhou HD. Chongqing Ageing Study Group.Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease. Neurology. 2011;76(17):1485-1491. IF=8.286 cite 106(被美國神經病學學會(AAN)舉行新聞發布,被引次數連續2年(2012、2013)位列2011年度神經病學領域論文前10位)7 Wang YJ, Wang X, Lu JJ, Li QX, Gao CY, Liu XH, Sun Y, Yang M, Lim Y, Evin G,Zhong JH,Masters C,Zhou XF. p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain. J Neurosci. 2011;9;31(6):2292-2304.
8 Wang YJ, Zhou HD, Li J, Zhang M, Deng J, Tang M, Gao C, Li J, Lian Y, Chen M. Leisure activity and risk of cognitive impairment: the Chongqing aging study. Neurology. 2006;66(6):911-913.(受到Neurology雜誌評論)
9 Liu YH, Bu XL, Liang CR, Wang YR, Zhang T, Jiao SS, Zeng F, Yao XQ, Zhou HD, Deng J, Wang YJ*. An N-terminal antibody promotes the transformation of amyloid fibrils into oligomers and enhances the neurotoxicity of amyloid-beta: the dust-raising effect.J Neuroinflammation. 2015;12(1):153.(發現Aβ清除“揚灰效應”機制)
10 Bu XL, Yao XQ, Jiao SS, Zeng F, Liu YH, Xiang Y, Liang CR, Wang QH, Wang X, Cao HY, Yi X, Deng B, Liu CH, Xu J, Zhang LL, Gao CY, Xu ZQ, Zhang M, Wang L, Tan XL, Xu X, Zhou HD, Wang YJ*. A study on the association between infectious burden and Alzheimer's disease. Eur J Neurol. 2015;22(12):1519-1525. (受到Eur J Neurol評論,被Nat Rev Neurol作為Research Highlight進行介紹)