王學東在醫藥企業工作多年，主要從事抗生素髮酵以及生物、生化藥物的研發與生產方面的工作，具有豐富的實際生產工作經驗。
基本介紹
- 中文名：王學東
- 外文名：WangDongXue
- 國籍：中國
- 民族：漢
- 出生地：河北
- 出生日期：1953年8月31日
- 職業：華東理工大學副研究員
- 性別：男
個人職位,研究方向,工作經歷,論著成果,申請專利,
個人職位
工學博士，副研究員。
研究方向
從事套用微生物發酵及酶催化方向的理論與套用方面的研究。
工作經歷
在華東理工大學生工學院從事科研工作，研究方向是生物催化與轉化以及相關的套用微生物發酵過程，通過理論與實際套用方面的研究，著力開發其工業化套用的潛能。承擔或參與了多項研究課題，主要有：手性胺基酸的酶法拆分；基因工程菌發酵法製備腺苷甲硫氨酸；生物轉化法製備神經節苷脂GM1等。在國內外檢索期刊上發表論文十餘篇，申請國家發明專利三項，獲省部級科技進步三等獎兩項。
論著成果
1. Xuedong Wang, etc. (2004) Development of an adsorption process for the direct separation and purification of prodigiosin from culture broth. Biotechnology Applied Biochemistry 40(3): 277-280.
2. Xuedong Wang, etc (2004) Simple method for large-scale isolation and purification of gangliosides by non-ionic adsorption chromatography Preparative Biochemistry & Biotechnology 34(4): 305–313.
3. Xuedong Wang, etc. Strategy for the improvement of prodigiosin production by a Serratia marcescens mutant through fed-batch fermentation World Journal of Microbiology and Biotechnology, 2005 21（6-7）,969-972
4. Xuedong Wang, etc (2005) Highly efficient conversion of polysialoganglioside to GM1 with Brevibacterium casei as a microbial biocatalyst Biocatalysis and Biotransformation 23(1): 29-32
5. Xuedong Wang, etc (2005) Reducing by-product formation in L-lactic acid fermentation by Rhizopus oryzae Journal of Industrial Microbiology & Biotechnology 32: 38-40
6. Yanfeng Peng, Xuedong Wang, Dongzhi Wei (2007) Development of a large scale process for the conversion of polysialogangliosides to monosialotetrahexosylganglioside with a novel strain of Brevibacterium casei producing sialidase Biotechnology Letters 29:885-889
7.Jianguo Zhang, Xuedong Wang, Yu Zheng, Guochen Fang, Dongzhi Wei (2008) Enhancing yield of S-adenosylmethionine in Pichia pastoris by controlling NH4 concentration Bioprocess Biosyst. Eng. 31:63–67
8.Jian-Guo Zhang, Xue-Dong Wang, Ji-Ning Zhang, Dong-Zhi Wei (2008) Oxygen Vectors Used for S-Adenosylmethionine Production in Recombinant Pichia pastoris with Sorbitol as Supplemental Carbon Source JOURNAL OF BIOSCIENCE AND BIOENGINEERING 105(4):335-340
9. Jian-Guo Zhang, Xue-Dong Wang, Dong-Zhi Wei (2009) High-level production of bovine enterokinase light chain using fed-batchs by recombinant Pichia pastoris Chemical Biochemical Engineering 23(2):219-224
10. 張建國，王學東，魏東芝 （2008）高效液相色譜法同時測定Pichia pastoris發酵過程中腺苷甲硫氨酸相關的六種物質 工業微生物 38（1）：6－9
11. 張建國，王學東，張魯嘉，周英，魏東芝，李軍 （2008）利用Pichia pastoris生產S－腺苷甲硫氨酸的發酵工藝 工業微生物 38（3）：6－11
12. Jianguo Zhang, Xuedong Wang, Erzheng Su, Guochen Fang, Yuhong Ren, DongzhiWei (2008) A new fermentation strategy for S-adenosylmethionine production in recombinant Pichia pastoris Biochemical Engineering Journal 41:74-78
13. Xu tao，Lujia Zhang, Erzheng Su, Dongbing Cui, Xuedong Wang, Dongzhi Wei （2010）Disparity in productive binding mode of the slow-reacting enantiomer determines the novel catalytic behavior of Candida antarctica lipase B Journal of Molecular Catalysis B: Enzymatic 62 (2010) 288–296
2. Xuedong Wang, etc (2004) Simple method for large-scale isolation and purification of gangliosides by non-ionic adsorption chromatography Preparative Biochemistry & Biotechnology 34(4): 305–313.
3. Xuedong Wang, etc. Strategy for the improvement of prodigiosin production by a Serratia marcescens mutant through fed-batch fermentation World Journal of Microbiology and Biotechnology, 2005 21（6-7）,969-972
4. Xuedong Wang, etc (2005) Highly efficient conversion of polysialoganglioside to GM1 with Brevibacterium casei as a microbial biocatalyst Biocatalysis and Biotransformation 23(1): 29-32
5. Xuedong Wang, etc (2005) Reducing by-product formation in L-lactic acid fermentation by Rhizopus oryzae Journal of Industrial Microbiology & Biotechnology 32: 38-40
6. Yanfeng Peng, Xuedong Wang, Dongzhi Wei (2007) Development of a large scale process for the conversion of polysialogangliosides to monosialotetrahexosylganglioside with a novel strain of Brevibacterium casei producing sialidase Biotechnology Letters 29:885-889
7.Jianguo Zhang, Xuedong Wang, Yu Zheng, Guochen Fang, Dongzhi Wei (2008) Enhancing yield of S-adenosylmethionine in Pichia pastoris by controlling NH4 concentration Bioprocess Biosyst. Eng. 31:63–67
8.Jian-Guo Zhang, Xue-Dong Wang, Ji-Ning Zhang, Dong-Zhi Wei (2008) Oxygen Vectors Used for S-Adenosylmethionine Production in Recombinant Pichia pastoris with Sorbitol as Supplemental Carbon Source JOURNAL OF BIOSCIENCE AND BIOENGINEERING 105(4):335-340
9. Jian-Guo Zhang, Xue-Dong Wang, Dong-Zhi Wei (2009) High-level production of bovine enterokinase light chain using fed-batchs by recombinant Pichia pastoris Chemical Biochemical Engineering 23(2):219-224
10. 張建國，王學東，魏東芝 （2008）高效液相色譜法同時測定Pichia pastoris發酵過程中腺苷甲硫氨酸相關的六種物質 工業微生物 38（1）：6－9
11. 張建國，王學東，張魯嘉，周英，魏東芝，李軍 （2008）利用Pichia pastoris生產S－腺苷甲硫氨酸的發酵工藝 工業微生物 38（3）：6－11
12. Jianguo Zhang, Xuedong Wang, Erzheng Su, Guochen Fang, Yuhong Ren, DongzhiWei (2008) A new fermentation strategy for S-adenosylmethionine production in recombinant Pichia pastoris Biochemical Engineering Journal 41:74-78
13. Xu tao，Lujia Zhang, Erzheng Su, Dongbing Cui, Xuedong Wang, Dongzhi Wei （2010）Disparity in productive binding mode of the slow-reacting enantiomer determines the novel catalytic behavior of Candida antarctica lipase B Journal of Molecular Catalysis B: Enzymatic 62 (2010) 288–296
