游常軍，男，博士，湖南大學化學化工學院教授，博士生導師。
基本介紹
- 中文名：游常軍
- 學位/學歷：博士
- 職業：教師
- 專業方向：化學化工
- 任職院校：湖南大學
人物經歷,研究領域,科研成果,學術成果,
人物經歷
化學修飾與分子毒理課題組負責人，Chemical Society Reviews、Journal of the American Chemical Society、 Analytical Chemistry、Chemical Communications、Chemical Research in Toxicology、 Environmental and Molecular Mutagenesis以及Science China Chemistry等國內外學術期刊審稿人。博士畢業於華中農業大學生命科學技術學院，獲得理學博士學位，隨後進入美國加州大學河濱分校化學系開展博士後研究工作。
研究領域
課題組目前的研究方向為生命分析化學和化學生物學，主要涉及生物質譜分析、核酸化學修飾及分子毒理學等方面的相關研究。
科研成果
至今已在國際主流學術期刊上發表SCI論文26篇，其中以第一作者在Accounts of Chemical Research、Nature Chemical Biology、Nature Protocols以及Nucleic Acids Research等國際權威期刊發表論文11篇，並以共同第一作者在美國科學院院刊PNAS 發表論文1篇。
學術成果
1、 You, C., Dai, X., and Wang, Y. Position-dependent effects of regioisomeric methylated adenine and guanine ribonucleosides on translation.Nucleic Acids Research,2017, 45: 9059-9067.
2.You, C., and Wang, Y. Mass spectrometry-based quantitative strategies for assessing the biological consequences and repair of DNA adducts.Accounts of Chemical Research, 2016, 49: 205-213.
3.You, C., Wang, P., Nay, S., Wang, J., Dai, X., O’Connor, T., and Wang, Y. Roles of AAG, ALKBH2 and ALKBH3 in the repair of carboxymethylated and ethylated thymidine lesions.ACS Chemical Biology, 2016, 11: 1332-1338.
4.You, C., and Wang, Y. Quantitative measurement of transcriptional inhibition and mutagenesis induced by site-specific DNA lesionsin vitroandin vivo.Nature Protocols, 2015, 10: 1389-1406.
5.You, C., Wang, J., Dai, X., and Wang, Y. Transcriptional inhibition and mutagenesis induced byN-nitroso compound-derived carboxymethylated thymidine adducts in DNA.Nucleic Acids Research,2015, 43: 1012-1018.
6.You, C., Wang, P., Dai, X., and Wang, Y. Transcriptional bypass of regioisomeric ethylated thymidine lesions by T7 RNA polymerase and human RNA polymerase II.Nucleic Acids Research,2014, 42:13706-13713.
7.You, C., Swanson, A., Dai, X., Yuan, B., Wang, J., and Wang Y. Translesion Synthesis of 8,5'-Cyclopurine-2'-deoxynucleosides by DNA Polymerases η, ι, and ζ.Journal of Biological Chemistry, 2013, 288, 28548-28556.
8.You, C., Dai, X., Yuan, B., and Wang, Y. Effects of 6-thioguanine andS-methylthioguanine on transcriptionin vitroand in human Cells.Journal of Biological Chemistry, 2012, 287:40915-23.
9.You, C., Dai, X., Yuan, B., Wang, J., Wang, J., Brooks, P., Niedernhofer, L., and Wang, Y. A quantitative assay for assessing the effects of DNA lesions on transcription.Nature Chemical Biology, 2012, 8, 817-822.
