沈英嘉,男,博士,廈門大學環境與生態學院教授。
基本介紹
- 中文名:沈英嘉
- 畢業院校:美國邁阿密大學
- 學位/學歷:博士
- 職業:教師
- 專業方向:生物信息學
- 任職院校:廈門大學
個人經歷,研究方向,開設課程,學術成果,榮譽獎勵,
個人經歷
- 上海師範大學 理學學士(2002)
- 上海師範大學 理學碩士(2005)
- 美國邁阿密大學博士(2009)
- 研究助理教授 美國德克薩斯州立大學(2010-2014)華盛頓大學聖路易斯(2013-2014)
- 廈門大學副教授(2014-現在)
- B.S. Shanghai Normal University(2002)
- M.S. Shanghai Normal University(2005)
- Ph.D in Botany, Miami University (2009)
- Research Assistant Professor, Texas State University(2010-2014), Washington University (2013-2014)
- Associate Professor, Xiamen University(2014-present)
研究方向
- 生物信息學;高通量測序技術的套用和開發;基因組和轉錄組的測序和拼接;比較基因組學
- Application of bioinformatic tools; Develop new methods in high-throughputSequencing technology; Sequencing and assembling of genome and transcriptome; Comparative genomics
開設課程
- 分子生物學基礎
- 專業外語
- 遺傳與進化
學術成果
代表性論文
- Yang K, Boswell M, Walter DJ, Downs KP, Gaston-Pravia K, Garcia T, Shen Y, Mitchell DL, Walter RB.UVB-induced Gene Expression in the Skin of XiphophorusmaculatusJp 163 B.Comp BiochemPhysiol C ToxicolPharmacol. 2014;
- Garcia TI, Matos I, Shen Y, Pabuwal V, Coelho MM, Wakamatsu Y, Schartl M, Walter RB. Novel method for analysis of allele specific expression in triploid Oryziaslatipes reveals consistent pattern of allele exclusion. PLoS One. 2014;
- Schartl M*+, Walter RB*+, Shen Y, GarciaT, Catchen, JC, Amores A, Braasch I, Chalopin D, Volff JN, Fuerstenberg S, Boore J, Lesch KP, Bisazza A, Minx P, Wilson RK, Postlethwait J, and Warren CW. The genome of the platyfish, Xiphophorusmaculatus: insights into complex traits. Nature Genetics. 2013;
- Pabuwal V, Boswell M, Pasquali A, Wise SS, Kumar S, Shen Y, Garcia T, Lacerte C, Wise JP Jr, Wise JP Sr, Warren W, Walter RB.Transcriptomic analysis of cultured whale skin cells exposed to hexavalent chromium [Cr(VI)]. AquatToxicol. 2013;
- Shen Y, Garcia T, Pabuwal V, Boswell M, Pasquali A, Beldorth I, Warren W, Schartl M, Cresko WA, Walter RB.Alternative strategies for development of a reference transcriptome for quantification of allele specific expression in organisms having sparse genomic resources.Comp Biochem Physiol Part D Genomics Proteomics. 2012
- Shen Y, Venu RC, Nobuta K, Wu X, Notibula V, Demirci C, Meyers BC, Wang GL, and Li QQ. Transcriptome Dynamics Through Alternative Polyadenylation in Developmental and Environmental Responses in PlantsRevealed by Deep Sequencing. Genome Research. 2011,
- Garcia T, Shen Y, Douglas Crawford D, Oleksiak MF,Whitehead A, Walter RB. RNA-Seq reveals complex genetic response to deepwater horizon oil release in Fundulus grandis.BMC genomics. 2012;
- Shen Y, Catchen J, Garcia T, Amores A, Beldroth I, Wagner JR, Zhang Z, Postlethwait JH, Warren W ,Schartl M, and Walter RB. Identification of SNPs between XiphophorusLines and Species for Assessing Allele Specific Gene Expression within Interspecies Hybrids. Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology. 2012 ,
- Kevin P. Downs, Yingjia Shen, Amanda Pasquali, Ion Beldorth, Markita Savage, Katelyn Gallier, Tzintzuni Garcia, Rachell E. Booth, Ronald B. Walter..Characterization of telomeres and telomerase expression in Xiphophorus. Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology. 2012,
- Garcia T, Shen Y, Catchen J, Amores A,Schartl M, Postlethwait JH and Walter RB. Effects of short read quality and quantity on a de novo vertebrate Transcriptome assembly. Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology. 2012,
- Zheng J, Xing D, Wu X, Shen Y, Kroll DM and Li QQ. Ratio-based Analysis of Differential mRNA Processing and Expression (RADPRE) of a Polyadenylation Factor Mutant Using Arabidopsis Genomic Tiling Microarray. PLoS ONE 2011
- Ji G, Wu X, Shen Y, Huang J, Wang Z and Li QQ. Dec 2010. Classification-Based Prediction Models of Messenger RNA Polyadenylation Sites. J Theor Biol. Aug 2010,
- Shen Y, Ji G, Haas B, Wu X, Zheng, J, Reese, G, Li, QQ. Genome level analysis of rice mRNA 3'-end processing signals and alternative polyadenylation. Nucleic Acids Research.May 2008,
- Shen Y, Liu Y, Liu L, Liang C, Li QQ. Genome level analysis of Chlamydomonasreinhardtii mRNA 3'-end processing signals and alternative polyadenylation. Genetics.2008,
- Liang C, Liu Y, Liu L, Davis AC, Shen Y and Li QQ. Expressed sequence tags with cDNA termini: previously overlooked resources for gene annotation and transcriptome exploration in Chlamydomonasreinhardtii. Genetics. 2008,
- Ji G, Zheng J, Shen Y, Wu X, Jiang R, Lin Y, Loke JC, Davis KM, Reese GJ, Li QQ. Predictive modeling of plant messenger RNA polyadenylation sites. BMC Bioinformatics. Feb 2007,
- Ji G, Wu XH, Zheng J, Shen Y and Li QQ. 2007.Modeling Plant mRNA Poly(A) sites: Software Design and Implementation. Journal of Computational and Theoretical Nanoscience. Nov 2007,
- Zhong X, Zhang C, Cui Y, Shen Y, Zhang Y, Yang Z. Isolation and Analysis of a High Expression Promoter in Rice. Chinese Journal of Biotechnology. Sep 2007,
- Shen Y, Chen DH. Effect of Different Light Cycle on Growth of Microcystisaeruginosa and Microcystisviridis. Journal of Lake Science. Jun 2005
- Shen Y, Jiang H, Jin JP, Zhang ZB, Xi B, He YY, Wang G, Wang C, Qian L, Li X, Yu QB, Liu HJ, Chen DH, Gao JH, Huang H, Shi TL, Yang ZN. Development of Genome-Wide DNA Polymorphism Database for Map-Based Cloning of Rice Genes. Plant Physiol. July 2004,
- Shen Y, Garcia T, Walter RB. Gene Expression Analysis Using RNA-Seq from Organisms Lacking Substantial Genomic Resources. Systems and Computational Biology - Molecular and Cellular Experimental Systems, 2011,
科研課題
- 增強劍尾魚作為模式生物的套用。美國國立衛生研究院。2011-2014
- 劍尾魚黑色素瘤生物標記鑑定。美國國立衛生研究院。2009-2013
- 擬南芥CPSF160蛋白的表達。邁阿密大學博士生和本科生科研促進項目。2008-2009
- 擬南芥CPSF160基因的結合特性的鑑定。Sigma Xi 。2007-2008
榮譽獎勵
- 邁阿密大學Charles Heimsch's優秀博士畢業生獎2009
- 邁阿密大學優秀論文獎學金2009
- 邁阿密大學研究生院研究生成就獎 2008
- 邁阿密大學校長學術貢獻獎學金2008
- 邁阿密大學博士生和本科生聯合研究獎學金2008
- 邁阿密大學學術挑戰研究基金2005,2007,2008
- Sigma Xi協會研究基金2007