人物履歷
2016.12- 武漢大學化學與分子科學學院 教授
2008.12-2016.11 武漢大學化學與分子科學學院 副教授(被遴選為分析化學(2010.07)和材料學專業(2012.06)博士生指導教師)
2011.06-2012.06
德國蒂賓根大學 物理化學與理論化學研究所 訪問學者
2006.07-2008.11 武漢大學化學與分子科學學院 講師(期間連續三年(3-4月/年)赴德國不萊梅Jacobs大學和韓國全南國立大學從事國際合作研究)
2001.09-2006.07 武漢大學化學與分子科學學院 分析化學 博士
1997.09-2001.06
湖北大學化學與材料科學學院 化學教育 學士
主授課程
1. 《現代儀器分析方法與實踐》(拉曼光譜)(研究生)
2. 《分析科學進展》(研究生)
3. 《材料科學進展》(研究生)
4. 《雷射分析》(研究生)
5. 《人文化學》(本科生通識課)
6. 《儀器分析實驗—紅外與拉曼光譜》(本科生)
學術兼職
湖北省化學化工學會譜學專業委員會秘書長
研究領域
1. 疾病(早期)診斷的拉曼光譜新技術與新儀器
2. 面向生物醫學、食品、環境及刑偵等領域中微量特徵物現場、快速分析的表面增強拉曼檢測新原理和新器件
3. 新型表面增強拉曼光譜分子探針用於多元感測分析和生物成像
科研項目
1. 主持人,國家自然科學基金面上項目,“突破衍射與顏色雙重極限的SERS顯微成 像新技術研究”,2019-2022,65萬(直接經費),批准號:21874102。
2. 主持人,國家自然科學基金面上項目,“突破衍射極限的針尖增強拉曼顯微鏡在細菌生物被膜無標記、高靈敏檢測中的套用”,2015-2018,90萬,批准號:21475100。
3. 主持人,國家重大科學儀器設備開發專項子項目,“雷射拉曼光譜氣體分析儀的研製”,2012-2015,218萬,批准號:2012YQ16000701。
4. 主持人,國家自然科學基金面上項目,“原位、活體檢測植物激素的SERS探針新技術”,2012-2015,60萬,批准號:21175101。
5. 主持人,國家自然科學基金青年科學基金項目,“新型複合拉曼探針用於胃癌早期診斷的研究”,2008-2010,20萬,批准號:20705025。
6. 主持人,中國石油科技創新基金項目,“改善二氧化碳驅油關鍵技術研究”,2008-2010,20萬。
代表性論文
1. Yi Zeng, Jia-Qiang Ren, Ai-Guo Shen, Ji-Ming Hu, Splicing nanoparticles-based ‘Click’ SERS could aid multiplex liquid biopsy and accurate cellular imaging, Journal of the American Chemical Society, 2018, 140, 10649-10652.
2. Ai-Guo Shen, Li-Fang Chen, Wei Xie, Jun-Cheng Hu, Ao Zeng, Ryan M Richards, Ji-Ming Hu, Triplex Au-Ag-C core-shell nanoparticles as a novel Raman labels, Advanced Functional Materials, 2010, 20, 969-975.
3. Xiang-Ru Bai, Li-Hua Wang, Jia-Qiang Ren, Xiang-Wei Bai, Ling-Wen Zeng, Ai-Guo Shen, Ji-Ming Hu, Accurate clinical diagnosis of liver cancer based on simultaneous detection of ternary specific antigens by magnetic induced mixing surface-enhanced Raman scattering emissions, Analytical Chemistry, 2019, DOI:10.1021/acs.analchem.8b05153.
4. Qian Lv, Huan Min, Dong-Ban Duan, Wei Fang, Gui-Ming Pan, Ai-Guo Shen, Qu-Quan Wang, Guang-Jun Nie, Ji-Ming Hu, Total aqueous synthesis of Au@Cu2-xS core-shell nanoparticles for in vitro and in vivo SERS/PA imaging-guided photothermal cancer therapy, Advanced Healthcare Materials, 2019, 8 (2), 1801257.
5. Qian Lv, Meng-Yue Gao, Zi-He Cheng, Qiao Chen, Ai-Guo Shen, Ji-Ming Hu, Rational synthesis of hollow cubic CuS@Spiky Au core-shell nanoparticles for enhanced photothermal and SERS effects, Chemical Communications, 2018, 54, 13399-13402.
6. Jun-Rong Li, Guan-Nan Zhang, Jing Wang, Ivan S. Maksymov, Andrew D. Greentree, Ji-Ming Hu, Ai-Guo Shen, Yu-Ling Wang, Matt Trau, Facile one-pot synthesis of nanodot-decorated gold-silver alloy nanoboxes for single-particle surface-enhanced Raman scattering activity, ACS Applied Materials undefinedamp; Interfaces, 2018, 10, 32526-32535.
7. Xiang-Ru Bai, Yi Zeng, Xiao-Dong Zhou, Xiao-Hua Wang, Ai-Guo Shen, Ji-Ming Hu, Environmentally safe mercury (II) ions aided zero-background and ultrasensitive SERS detection of dipicolinic acid, Analytical Chemistry, 2017, 89, 10335-10342.
8. Yi Zeng, Jia-Qiang Ren, Shao-Kai Wang, Jia-Ming Mai, Bing Qu, Yan Zhang, Ai-Guo Shen*, Ji-Ming Hu, Rapid and reliable detection of alkaline phosphatase by a hot spots amplification strategy based on well-controlled assembly on single nanoparticle, ACS Applied Materials undefinedamp; Interfaces, 2017, 9, 29547-29553.
9. Yi Zeng, Jia-Qiang Ren, Ai-Guo Shen, Ji-Ming Hu, Field and pretreatment-free detection of heavy-metal ions in organic polluted water through an alkyne-coded SERS test kit, ACS Applied Materials undefinedamp; Interfaces, 2016, 8, 27772-27778.
10. Yong Chen, Jia-Qiang Ren, Xia-Guang Zhang, De-Yin Wu, Ai-Guo Shen, Ji-Ming Hu, Alkyne-modulated surface-enhanced Raman scattering-palette for optical interference-free and multiplex cellular imaging, Analytical Chemistry, 2016, 88, 6115-6119.
11. Wei Fang, Xin-Wei Zhang, Yong Chen, Liang Wan, Wei-Hua Huang, Ai-Guo Shen, Ji-Ming Hu, Portable SERS-enabled micropipettes for microarea sampling and reliably quantitative detection of surface organic residues, Analytical Chemistry, 2015, 87, 9217-9224.
12. Yong Chen, Xiang-Ru Bai, Le Su, Zhan-Wei Du, Ai-Guo Shen, Arnulf Materny, Ji-Ming Hu, Combined labelled and label-free SERS probes for triplex three-dimensional cellular imaging, Scientific Reports, 2016, 6, 19173.
13. Yi Zeng, Jin-Ju Pei, Li-Hua Wang, Ai-Guo Shen, Ji-Ming Hu, A sensitive sequential "on/off" SERS assay for heparin with wider detection window and higher reliability based on the reversed surface charge changes of functionalized Au@Ag nanoparticles, Biosensors and Bioelectronics, 2015, 66, 55-61.
14. Li-Hua Wang, Yi Zeng, Ai-Guo Shen, Xiao-Dong Zhou, Ji-Ming Hu, Three dimensional nano-assemblies of noble metal nanoparticle-infinite coordination polymers as specific oxidase mimetics for degradation of methylene blue without adding any cosubstrate, Chemical Communications, 2015, 51, 2052-2055.
15. Gan Qu, Guan-Nan Zhang, Zi-Tong Wu, Ai-Guo Shen, Jian-Bo Wang, Ji-Ming Hu, A "turn-off" SERS assay of heparin with high selectivity based on heparin-peptide complex and Raman labelled gold nanoparticles, Biosensors and Bioelectronics, 2014, 60, 124-129.
16. Zi-Tong Wu, Yi-Zhen Liu, Xiao-Dong Zhou, Ai-Guo Shen, Ji-Ming Hu, A "turn-off" SERS-based detection platform for ultra-sensitive detection of thrombin based on enzymatic assays, Biosensors and Bioelectronics, 2013, 44, 10-15.