《比較蛋白質組學的生物信息學（影印版）》是2013年科學出版社出版的圖書。
基本介紹
- 書名：比較蛋白質組學的生物信息學（影印版）
- 作者：（美）C. H.Wu 等
- 出版社：科學出版社
- 出版時間：2013年4月
- 版本：1
基本信息,內容簡介,書評和推薦,目錄,
基本信息
（美）C. H.Wu 等
語種：中文
ISBN：978-7-03-036990-1
裝幀：平裝
內容簡介
隨著生命科學和臨床套用蛋白質組學技術的快速發展，許多生物信息學的研究方法、資料庫、軟體工具已經可以用於支持比較蛋白質組學的研究。《比較蛋白質組學的生物信息學（影印版）》分為3個主要部分，包括與比較蛋白質組學相關的基礎生物信息學框架、蛋白質組學數據分析的生物信息學資料庫和工具，以及在系統生物學背景下的比較蛋白質組學關於整合生物信息的系統學和研究方法。本書提供了詳細的操作建議，逐步地描述操作過程，務求讓使用者在實驗室獲得最佳的實驗結果。
書評和推薦
蛋白質組學技術的飛速發展，催生了海量數據。這些數據的收集、存儲、整理和分析給生物信息學帶來了挑戰。在這些方面，國內相關的生物信息學研究有了一定的研究基礎，但在相關知識的普及教育方面非常欠缺，最明顯的是國內尚沒有一本蛋白質組信息學的專著。國內正需要一本這種深入淺出、全方位介紹比較蛋白質組數據處理的科學讀本，能在基礎與套用層面上起到指引的作用。但凡科學離不開技術，但凡數據離不開分析。特別在眼下生命科學研究組學化、組學研究系統化的大趨勢下，國內蛋白質組學的瓶頸已不再是儀器和實驗，而是實驗設計和數據分析。引入該書對加強、提升我國蛋白組學數據分析能力，著力於突破目前的瓶頸會起到巨大的推動作用。——賀福初軍事醫學科學院
目錄
PrefaceContributors
PART I: BIOINFORMATICS FRAMEWORK FOR COMPARATIVE PROTEOMICS
1 Protein Bioinformatics Databases and Resources Churning Chen, Hongzhan Huang, and Cathy H. Wu
2 A Guide to UniProt for Protein Scientists Claire O'Donovan and Rolf Apweiler
3 InterPro Protein Classification Jennifer McDowall and Sarah Hunter
4 Reactome Knowledgebase of Human Biological Pathways and Processes Peter D'Eustachio
5 eFIP: A Tool for Mining Functional Impact of Phosphorylation from Literature Cecilia N. Arighi, Amy Y. Siu, Catalina O. Tudor, Jules A. Nchoutrnboube, Cathy It. Wu, and Vijay K. Shanker
6 A Tutorial on Protein Ontology Resources for Proteomic Studies Cecilia N. Arighi
7 Structure-Guided Rule-Based Annotation. of Protein Functional Sites in UniProt Knowledgebase Sona Vasudevan, C.R. Vinayaka, Darren A. Natale, Hongzhan Huang, Robel Y. Kahsay, and Cathy H. Wu
PART II: PROTEOMIC BIOINFORMATICS
8 Modeling Mass Spectrometry-Based Protein Analysis Jan Eriksson and David Feny
9 Protein Identification from Tandem Mass Spectra by Database Searching Nathan J. Edwards
10 LC-MS Data Analysis for Differential Protein Expression Detection Rency S. Varghese and Habtorn W. Ressom
11 Protein Identification by Spectral Networks Analysis Nuno Bandeira
12 Software Pipeline and Data Analysis for MS/MS Proteomics: The Trans-Proteomic Pipeline Andrew Keller and David Shteynberg
13 Analysis of High-Throughput ELISA Microarray Data Amanda M. White, Don S. Daly, and Richard C. Zangar
14 Proteomics Databases and Repositories Lennart Martens
15 Preparing Molecular Interaction Data for Publication Sandra Orchard and Henning Hermjakob
16 Submitting Proteomics Data to PRIDE Using PRIDE Converter Harald Barsnes, Juan Antonio Vizcalno, Florian Reisinger, Ingvar Eidhammer, and Lennart Martens
17 Automated Data Integration and Determination of Posttranslational Modifications with the Protein Inference Engine Stuart R. Jefferys and Morgan C. Giddings
18 An Integrated Top-Down and Bottom-Up Strategy for Characterization of Protein Isoforms and Modifications Si Wu, Nikola Toli, Zhixin Tian, Errol W. Robinson, and Ljiljana Paa- Toli
PART III: COMPARATIVE PROTEOMICS IN SYSTEMS BIOLOGY
19 Phosphoproteome Resource for Systems Biology Research Bernd Bodenmiller and Ruedi Aebersold
20 Protein-Centric Data Integration for Functional Analysis of Comparative Proteomics Data Peter B. McGarvey, Jian Zhang, Darren A. Natale, Cathy H. Wu, and Hongzhan Huang
21 Integration of Proteomic and Metabolomic Profiling as well as Metabolic Modeling for the Functional Analysis of Metabolic Networks Patrick May, Nils Christian, Oliver Ebenhh, Wolfram Weckwerth, and Dirk Walther
22 Time Series Proteome Profiling Catherine A. Formolo, Michelle Mint4 Asako Takanohashi, Kristy J. Brown, Adeline Vanderver, Brian Halligan, and Yetrib Hathout Index
