步宏(四川大學華西醫院病理科教授、臨床病理研究所所長)

步宏，四川大學華西醫院病理科教授、博士生導師、臨床病理研究所所長。國務院學位委員會學科評議組成員。

曾任四川大學副校長。

基本介紹

• 中文名：步宏
• 國籍：中國
• 畢業院校：寧夏醫學院
• 學歷：博士研究生
• 教學職稱：教授
• 臨床職稱：病理科副主任
• 執業地點：四川大學華西醫院
• 職業：醫生

人物經歷

1982年畢業於寧夏醫學院。

步宏

1982～1993年曆任原華西醫科大學病理教研室/病理科助教、講師。

1992～2005年任病理教研室/病理科副主任，病理實驗室主任。

1993年在原華西醫科大學獲醫學博士學位，同年晉升副教授。

1994年赴香港大學研修。

2000年晉升教授。

2001年遴選為博士生導師。

曾任四川大學副校長。

任免信息

2017年5月25日下午，四川大學召開學校黨政副職宣布會議，宣布教育部黨組關於四川大學黨政領導班子局部調整的決定。因年齡和任職年限原因，免去步宏同志的職務。

學術任職

中華醫學會病理學分會主任委員、首屆CSCO腫瘤病理專家委員會主任委員、中國抗癌協會腫瘤病理專業委員會主任委員、衛生部全國病理質控中心專家委員會副主任委員、衛生部全國腫瘤規範化診療專家委員會委員。《中華病理學雜誌》、《臨床與實驗病理學雜誌》、《中國肺癌雜誌》、《診斷病理學雜誌》等期刊常務編委和編委。教育部教學評估專家，教育部學科建設委員會委員，教育部醫學人文教指委副主任委員。

亞專業

從事乳腺病理及分子病理學診斷和研究。專業業務工作主要是引領乳腺疾病小組開展對乳腺疾病的病理診斷、分子病理診斷及研究工作。並承擔醫學生和研究生的授課工作。

出版圖書

科研成果

科研成果：作為負責人和主研人員近年獲國家973計畫項目、國家自然科學基金重大項目、國家自然科學基金面上項目、教育部博士點基金等10餘項資助，以第一作者和通訊作者已發表SCI收錄論文100餘篇。曾獲國家教學成果二等獎和四川省科技進步一等獎及二等獎多項。獲全國百篇優博論文指導教師獎。

步宏

主要著作

《分子病理學:疾病的分子基礎》威廉·B.科爾曼 等 著 步宏等 譯，科學出版社，2012-03-01

《分子病理學進展》，四川大學出版社，2006-11-01

《病理學》，人民衛生出版社，2002-08-01

《病理學綱要》，科學出版社，:2003-05-01

《病理學與病理生理學》(供本科護理學類專業)(第2版)，人民衛生出版社，2006-7-1

《實用組織病理學技術手冊》

《跨世紀醫學教學研究與改革》

主要論文

Q, Li Y, Wang Y, Li L, Jiang X, Tang J, Yang H, Zhang J, Bao J, Bu H. The effect of heparinized decellularized scaffolds on angiogenic capability. J Biomed Mater Res A. 2016 Dec;104(12):3021-3030. doi: 10.1002/jbm.a.35843. PubMed PMID:27459086.

步宏

Deng S, Jin T, Zhang L, Bu H, Zhang P. Mechanism of tacrolimus-induced chronic renal fibrosis following transplantation is regulated by ox-LDL and its receptor, LOX-1. Mol Med Rep. 2016 Nov;14(5):4124-4134. doi: 10.3892/mmr.2016.5735. PubMed

PMID: 27633115.

Li Y, Wang Y, Wu Q, Li L, Shi Y, Bu H, Bao J. Comparison of methods for isolating primary hepatocytes from mini pigs. Xenotransplantation. 2016 Sep;23(5):414-20. doi: 10.1111/xen.12259. PubMed PMID: 27596934.

Kong L, Zhou Y, Bu H, Lv T, Shi Y, Yang J. Deletion of interleukin-6 in monocytes/macrophages suppresses the initiation of hepatocellular carcinoma in mice. J Exp Clin Cancer Res. 2016 Sep 2;35(1):131. doi:10.1186/s13046-016-0412-1. PubMed PMID: 27589954; PubMed Central PMCID: PMC5009700.

Zhong X, Xie G, Zhang Z, Wang Z, Wang Y, Wang Y, Qiu Y, Li L, Bu H, Li J, Zheng H. MiR-4653-3p and its target gene FRS2 are prognostic biomarkers for hormone receptor positive breast cancer patients receiving tamoxifen as adjuvant endocrine therapy. Oncotarget. 2016Aug 13. doi: 10.18632/oncotarget.11278. PubMed PMID: 27533459.

Zhu M, Bu H, Peng YL. Letter to the Editor: Vascular tumor versus vascular malformation of the internal auditory canal. J Neurosurg. 2016 Sep;125(3):785. doi: 10.3171/2016.3.JNS16657. PubMed PMID: 27419829.

Bao J, Wu Q, Wang Y, Li Y, Li L, Chen F, Wu X, Xie M, Bu H. Enhanced hepatic differentiation of rat bone marrow-derived mesenchymal stem cells in spheroid aggregate culture on a decellularized liver scaffold. Int J Mol Med. 2016 Aug;38(2):457-65.

Lu F, Chen Y, Zhao C, Wang H, He D, Xu L, Wang J, He X, Deng Y, Lu EE, Liu X, Verma R, Bu H, Drissi R, Fouladi M, Stemmer-Rachamimov AO, Burns D, Xin M, Rubin JB, Bahassi el M, Canoll P, Holland EC, Lu QR. Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma. Cancer Cell. 2016 May 9;29(5):669-83. doi:

10.1016/j.ccell.2016.03.027. PubMed PMID: 27165742; PubMed Central PMCID: PMC4946168.

Wang Y, Bao J, Wu X, Wu Q, Li Y, Zhou Y, Li L, Bu H. Genipin crosslinking

reduced the immunogenicity of xenogeneic decellularized porcine whole-liver matrices through regulation of immune cell proliferation and polarization. Sci Rep. 2016 Apr 21;6:24779. doi: 10.1038/srep24779. PubMed PMID: 27098308; PubMed Central PMCID: PMC4838870.

Yang L, Wang Y, Shi Y, Bu H, Ye F. Deletion of SIP1 promotes liver regeneration and lipid accumulation. Pathol Res Pract. 2016 May;212(5):421-5. doi: 10.1016/j.prp.2016.02.015. PubMed PMID: 26936023.

Wang E, Zhu M, Bu H, Chen J, Ding Y, Zhou X, Liang Z, Zhang X, Sun B; Thoracic Disease Study Group of Chinese Society of Pathology.; Molecular Pathology Study Group of National Health and Family Planning Commission Pathology Quality Control Center.; Molecular Pathology Study Group of Chinese Pathologist Association.; Molecular Pathology Study Group of Chinese Anti Cancer Association of Tumor Pathology.. [Consensus of Chinese experts on detection of related drive genes in target therapy of non-small cell lung cancer]. Zhonghua Bing Li Xue Za Zhi. 2016 Feb;45(2):73-7. doi: 10.3760/cma.j.issn.0529-5807.2016.02.001. Chinese. PubMed PMID: 26879425.

Zhou Y, Zhang L, Ji H, Lu X, Xia J, Li L, Chen F, Bu H, Shi Y. MiR-17~92 ablation impairs liver regeneration in an estrogen-dependent manner. J Cell Mol Med. 2016 May;20(5):939-48. doi: 10.1111/jcmm.12782. PubMed PMID: 26781774;PubMed Central PMCID: PMC4831359.

Chinese Society of Pathology, Chinese Pathologist Association, Committee of Oncopathology of Chinese Anticancer Association, Pathology Quality Control Center of China, National Steering Committee of Molecular Pathology.; Chinese Society of Pathology Chinese Pathologist Association Committee of Oncopathology of Chinese Anticancer Association Pathology Quality Control Center of China National

Steering Committee of Molecular Pathology.. [Guideline of construction of molecular pathology laboratory]. Zhonghua Bing Li Xue Za Zhi. 2015 Jun;44(6):369-71. Chinese. PubMed PMID: 26704828.

Qiu Y, Pu T, Guo P, Wei B, Zhang Z, Zhang H, Zhong X, Zheng H, Chen L, Bu H, Ye F. ALDH(+)/CD44(+) cells in breast cancer are associated with worse prognosis and poor clinical outcome. Exp Mol Pathol. 2016 Feb;100(1):145-50. doi: 10.1016/j.yexmp.2015.11.032. PubMed PMID: 26687806.

Pu T, Guo P, Qiu Y, Chen S, Yang L, Sun L, Ye F, Bu H. Quantitative real-time polymerase chain reaction is an alternative method for the detection of HER-2 amplification in formalin-fixed paraffin-embedded breast cancer samples. Int J Clin Exp Pathol. 2015 Sep 1;8(9):10565-74. PubMed PMID: 26617766; PubMed Central PMCID: PMC4637581.

Zhou QH, Fan YG, Bu H, Wang Y, Wu N, Huang YC, Wang G, Wang XY, Qiao YL. China national lung cancer screening guideline with low-dose computed tomography (2015 version). Thorac Cancer. 2015 Nov;6(6):812-8. doi: 10.1111/1759-7714.12287. PubMed PMID: 26557925; PubMed Central PMCID: PMC4632939.

Bao J, Sun J, Zhou Y, Wu Q, Wang Yujia, Li L, Jiang X, Ma L, Xie Mingjun, Shi Y, Bu H. [Anticoagulant Ability and Heparinization of Decellularized Biomaterial Scaffolds]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2015 Jun;32(3):594-8. Chinese.PubMed PMID: 26485984.

Ye F, Qiu Y, Li L, Yang L, Cheng F, Zhang H, Wei B, Zhang Z, Sun L, Bu H. The Presence of EpCAM(-)/CD49f(+) Cells in Breast Cancer Is Associated with a Poor Clinical Outcome. J Breast Cancer. 2015 Sep;18(3):242-8. doi:10.4048/jbc.2015.18.3.242. PubMed PMID: 26472974; PubMed Central PMCID:PMC4600688.

Lu C, Xia J, Zhou Y, Lu X, Zhang L, Gou M, Li L, Zhang X, Ji H, Zhu K, Li L, Zhang J, Yu P, Yang J, Bu H, Shi Y. Loss of Gsα impairs liver regeneration through a defect in the crosstalk between cAMP and growth factor signaling. J Hepatol. 2016 Feb;64(2):342-51. doi: 10.1016/j.jhep.2015.08.036. PubMed PMID:26386161.

Yang LB, Sun LY, Jiang Y, Tang Y, Li ZH, Zhang HY, Bu H, Ye F. The Clinicopathological Features of BRAF Mutated Papillary Thyroid Cancers in Chinese Patients. Int J Endocrinol. 2015;2015:642046. doi: 10.1155/2015/642046. PubMed PMID: 26273300; PubMed Central PMCID: PMC4530233.

Lu C, Zhang Z, Jiang Y, Yang Z, Yang Q, Liao D, Bu H. Primary pure carcinoid tumors of the testis: Clinicopathological and immunophenotypical characteristics of 11 cases. Oncol Lett. 2015 May;9(5):2017-2022. PubMed PMID: 26137005; PubMed Central PMCID: PMC4467263.

He Y, Wang W, Xu L, Li L, Liu J, Feng M, Bu H. Immunohistochemical Expression and Prognostic Significance of CD97 and its Ligand DAF in Human Cervical Squamous Cell Carcinoma. Int J Gynecol Pathol. 2015 Sep;34(5):473-9. doi:10.1097/PGP.0000000000000200. PubMed PMID: 26107567.

Zhou P, Xia J, Zhou YJ, Wan J, Li L, Bao J, Shi YJ, Bu H. Proportions of acetyl-histone-positive hepatocytes indicate the functional status and prognosis of cirrhotic patients. World J Gastroenterol. 2015 Jun 7;21(21):6665-74. doi:10.3748/wjg.v21.i21.6665. PubMed PMID: 26074705; PubMed Central PMCID:PMC4458777.

Lu XF, Zhou YJ, Zhang L, Ji HJ, Li L, Shi YJ, Bu H. Loss of Dicer1 impairs hepatocyte survival and leads to chronic inflammation and progenitor cell activation. World J Gastroenterol. 2015 Jun 7;21(21):6591-603. doi:10.3748/wjg.v21.i21.6591. PubMed PMID: 26074697; PubMed Central PMCID:PMC4458769.

Bao J, Wu Q, Sun J, Zhou Y, Wang Y, Jiang X, Li L, Shi Y, Bu H.Hemocompatibility improvement of perfusion-decellularized clinical-scale liver scaffold through heparin immobilization. Sci Rep. 2015 Jun 1;5:10756. doi:10.1038/srep10756. PubMed PMID: 26030843.

Guideline Recommendations for Immunohistochemistry Detection in Breast Cancer Group.. [Guideline for testing of estrogen and progesterone receptors in breast cancer]. Zhonghua Bing Li Xue Za Zhi. 2015 Apr;44(4):237-9. Chinese. PubMed PMID:25975904.

Consensus Group for Neoadjuvant Chemotherapy of Breast Carcinomas.[Pathology of breast carcinomas after neoadjuvant chemotherapy: an expert consensus]. Zhonghua Bing Li Xue Za Zhi. 2015 Apr;44(4):232-6. Chinese. PubMed PMID: 25975903.

Yang W, Bu H. [Review of Guideline for Detection of HER2 in Breast Cancer (2014) after one-year release]. Zhonghua Bing Li Xue Za Zhi. 2015 Apr;44(4):227-9. Review. Chinese. PubMed PMID: 25975901.

Du Z, Zhou Y, Lu X, Li L, Lu C, Li L, Li B, Bu H, Yang J, Shi Y. Octreotide prevents liver failure through upregulating 5'-methylthioadenosine in extended hepatectomized rats. Liver Int. 2016 Feb;36(2):212-22. doi: 10.1111/liv.12863. PubMed PMID: 25944273.

Wu Q, Bao J, Zhou YJ, Wang YJ, Du ZG, Shi YJ, Li L, Bu H. Optimizing perfusion-decellularization methods of porcine livers for clinical-scale whole-organ bioengineering. Biomed Res Int. 2015;2015:785474. doi:10.1155/2015/785474. PubMed PMID: 25918720; PubMed Central PMCID: PMC4396818.

Deng L, Chen J, Zhong XR, Luo T, Wang YP, Huang HF, Yin LJ, Qiu Y, Bu H, Lv Q, Zheng H. Correlation between activation of PI3K/AKT/mTOR pathway and prognosis of breast cancer in Chinese women. PLoS One. 2015 Mar 27;10(3):e0120511. doi:10.1371/journal.pone.0120511. PubMed PMID: 25816324; PubMed Central PMCID:PMC4376391.

Yang W, Wei B, Chen M, Bu H. [Evaluation of immunohistochemistry HER2 results interpretation in invasive micropapillary carcinoma of the breast]. Zhonghua Bing Li Xue Za Zhi. 2015 Jan;44(1):48-52. Chinese. PubMed PMID: 25765031.

Li Y, Guo G, Li L, Chen F, Bao J, Shi YJ, Bu H. Three-dimensional spheroid culture of human umbilical cord mesenchymal stem cells promotes cell yield and stemness maintenance. Cell Tissue Res. 2015 May;360(2):297-307. doi: 10.1007/s00441-014-2055-x. PubMed PMID: 25749992.

Lu C, Qiu Y, Lu X, Li G, Bu H. Synchronous diffuse ganglioneuromatosis and multiple schwannomas of the colon: A case report and literature review. Exp Ther Med. 2015 Mar;9(3):733-736. PubMed PMID: 25667620; PubMed Central PMCID: PMC4316863.

Zhang Z, Bu H, Huang H, Zhang J, Lang Z, Zhao T, Wang J, Liao D, Wei B. [Matrix-producing metaplastic carcinoma: a clinicopathologic and prognostic analysis of 16 cases with review of literature]. Zhonghua Bing Li Xue Za Zhi. 2014 Aug;43(8):528-32. Chinese. PubMed PMID: 25346122.

Wang Y, Bao J, Wu Q, Zhou Y, Li Y, Wu X, Shi Y, Li L, Bu H. Method for perfusion decellularization of porcine whole liver and kidney for use as a scaffold for clinical-scale bioengineering engrafts. Xenotransplantation. 2015 Jan-Feb;22(1):48-61. doi: 10.1111/xen.12141. PubMed PMID: 25291435.

Yin C, Zhang T, Qiao L, Du J, Li S, Zhao H, Wang F, Huang Q, Meng W, Zhu H, Bu H, Li H, Xu H, Mo X. TLR7-expressing cells comprise an interfollicular epidermal stem cell population in murine epidermis. Sci Rep. 2014 Jul 25;4:5831. doi: 10.1038/srep05831. PubMed PMID: 25060222.

Wu HK, Wang W, Li H, Bu H, Zhang P. [The mechanism of ciclosporin A regulating the expression of LOX-1 on vascular endothelium of hyperlipidemic rats]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2014 May;45(3):371-5. Chinese. PubMed

PMID: 24941799.

Guideline Recommendations for HER2 Detection in Breast Cancer Group.Guidelines for HER2 detection in breast cancer, the 2014 version. Zhonghua Bing Li Xue Za Zhi. 2014 Apr;43(4):262-7. Chinese. PubMed PMID: 24915819.

Zhong X, Luo T, Zheng H, Bu H. [New challenges of personalized therapy for breast cancer to pathologists]. Zhonghua Bing Li Xue Za Zhi. 2014 Apr;43(4):219-21. Chinese. PubMed PMID: 24915809.

Bu H, Yang W. [To improve the quality of pathologic diagnosis through standardized HER2 testing]. Zhonghua Bing Li Xue Za Zhi. 2014 Apr;43(4):217-8. Chinese. PubMed PMID: 24915808.

Qiu Y, Pu T, Li L, Cheng F, Lu C, Sun L, Teng X, Ye F, Bu H. The expression of aldehyde dehydrogenase family in breast cancer. J Breast Cancer. 2014 Mar;17(1):54-60. doi: 10.4048/jbc.2014.17.1.54. PubMed PMID: 24744798; PubMed Central PMCID: PMC3988343.

Zhang Z, Wang J, Skinner KA, Shayne M, Hajdu SI, Bu H, Hicks DG, Tang P. Pathological features and clinical outcomes of breast cancer according to levels of oestrogen receptor expression. Histopathology. 2014;65(4):508-16. doi: 10.1111/his.12412. PubMed PMID: 24620991.

Cheng L, Bu H, Portillo JA, Li Y, Subauste CS, Huang SS, Kern TS, Lin F. Modulation of retinal Müller cells by complement receptor C5aR. Invest Ophthalmol Vis Sci. 2013 Dec 17;54(13):8191-8. doi: 10.1167/iovs.13-12428. PubMed PMID: 24265019; PubMed Central PMCID: PMC3867184.

Ye F, Chen Y, He D, Jian SY, Zheng K, Li GD, Bu H. [Detection of Mycobacterium tuberculosis complex in paraffin-embedded tissues by real-time fluorescent quantitative polymerase chain reaction]. Zhonghua Bing Li Xue Za Zhi. 2013 Aug;42(8):534-7. Chinese. PubMed PMID: 24246919.

Huang D, Lu N, Fan Q, Sheng W, Bu H, Jin X, Li G, Liu Y, Li X, Sun W, Zhang H, Li X, Zhou Z, Yan M, Wang X, Sha W, Ji J, Cheng X, Zhou Z, Xu J, Du X. HER2 status in gastric and gastroesophageal junction cancer assessed by local and central laboratories: Chinese results of the HER-EAGLE study. PLoS One. 2013 Nov 14;8(11):e80290. doi: 10.1371/journal.pone.0080290. PubMed PMID: 24244671; PubMed Central PMCID: PMC3828190.

Zhang Z, Wang J, Tacha DE, Li P, Bremer RE, Chen H, Wei B, Xiao X, Da J, Skinner K, Hicks DG, Bu H, Tang P. Folate receptor α associated with triple-negative breast cancer and poor prognosis. Arch Pathol Lab Med. 2014 Jul;138(7):890-5. doi: 10.5858/arpa.2013-0309-OA. PubMed PMID: 24028341.

Zhi X, Wu Y, Ma S, Wang T, Wang C, Wang J, Shi Y, Lu Y, Liu L, Liu D, Chen D, Yang Y, Du X, Bu H, Zhou Q, Jang G, Han B, Cheng G, Cheng Y, Jiao S. [Chinese guidelines on the diagnosis and treatment of primary lung cancer (2011version)]. Zhongguo Fei Ai Za Zhi. 2012 Dec;15(12):677-88. doi:10.3779/j.issn.1009-3419.2012.12.01. Chinese. PubMed PMID: 23249713.

Ni Y, Xie X, Bu H, Zhang Z, Wei B, Yin L, Chen M, Chen H, Zhang H. Concurrent primary angiosarcoma and invasive ductal carcinoma in the same breast. J Clin Pathol. 2013 Mar;66(3):263-4. doi: 10.1136/jclinpath-2012-201233. PubMed PMID:23172554.

Yin L, Chen M, Ye F, Bu H, Bai H, Yu J, Zhang H. A poorly differentiated synovial sarcoma arising from the pulmonary valve. Cardiovasc Pathol. 2013 Nov-Dec;22(6):501-2. doi: 10.1016/j.carpath.2013.04.004. PubMed PMID: 23701986.

Xia J, Zhou Y, Ji H, Wang Y, Wu Q, Bao J, Ye F, Shi Y, Bu H. Loss of histone deacetylases 1 and 2 in hepatocytes impairs murine liver regeneration through Ki67 depletion. Hepatology. 2013 Dec;58(6):2089-98. doi: 10.1002/hep.26542. PubMed PMID: 23744762.

Cheng L, Shi Y, Ye F, Bu H. Osteoinduction of calcium phosphate biomaterials in small animals. Mater Sci Eng C Mater Biol Appl. 2013 Apr 1;33(3):1254-60. doi:10.1016/j.msec.2012.12.023. PubMed PMID: 23827569.

Ye F, Chen Y, He D, Jian SY, Zheng K, Li GD, Bu H. Detection of Mycobacterium tuberculosis complex in paraffin-embedded tissues by real-time fluorescent quantitative polymerase chain reaction . Zhonghua Bing Li Xue Za Zhi. 2013 Aug;42(8):534-7. Chinese. PubMed PMID: 24246919.

Cheng L, Shi Y, Ye F, Bu H. Osteoinduction of calcium phosphate biomaterials in small animals. Mater Sci Eng C Mater Biol Appl. 2013 Apr 1;33(3):1254-60. doi: 10.1016/j.msec.2012.12.023. Epub 2012 Dec 9. PubMed PMID: 23827569.

Ke Q, Yang RN, Ye F, Wang YJ, Wu Q, Li L, Bu H. Impairment of liver regeneration by the histone deacetylase inhibitor valproic acid in mice. J Zhejiang Univ Sci B. 2012 Sep;13(9):695-706. PubMed PMID: 22949360; PubMed Central PMCID: PMC3437367.

Guo G, Xia J, Bao J, Sun HQ, Shi YJ, Bu H. Expression of SOCS3 throughout liver regeneration is not regulated by DNA methylation. Hepatobiliary Pancreat Dis Int. 2012 Aug 15;11(4):401-6. PubMed PMID: 22893467.

Zhou P, Xia J, Guo G, Huang ZX, Lu Q, Li L, Li HX, Shi YJ, Bu H. A Macaca mulatta model of fulminant hepatic failure. World J Gastroenterol. 2012 Feb 7;18(5):435-44. doi: 10.3748/wjg.v18.i5.435. PubMed PMID: 22346249; PubMed Central PMCID: PMC3270505.

Shi Y, Sun H, Bao J, Zhou P, Zhang J, Li L, Bu H. Activation of inactive hepatocytes through histone acetylation: a mechanism for functional compensation after massive loss of hepatocytes. Am J Pathol. 2011 Sep;179(3):1138-47. doi: 10.1016/j.ajpath.2011.05.029. Epub 2011 Jul 16. PubMed PMID: 21763259; PubMed Central PMCID: PMC3157283.

Yang RN, Ye F, Cheng LJ, Wang JJ, Lu XF, Shi YJ, Fan HS, Zhang XD, Bu H. Osteoinduction by Ca-P biomaterials implanted into the muscles of mice. J Zhejiang Univ Sci B. 2011 Jul;12(7):582-90. doi: 10.1631/jzus.B1000204. PubMed PMID: 21726066; PubMed Central PMCID: PMC3134847.

Bao J, Shi Y, Sun H, Yin X, Yang R, Li L, Chen X, Bu H. Construction of a portal implantable functional tissue-engineered liver using perfusion-decellularized matrix and hepatocytes in rats. Cell Transplant. 2011;20(5):753-66. doi: 10.3727/096368910X536572. Epub 2010 Nov 5. PubMed PMID: 21054928.

Zhang R, Chen HJ, Wei B, Zhang HY, Pang ZG, Zhu H, Zhang Z, Fu J, Bu H. Reproducibility of the Nottingham modification of the Scarff-Bloom-Richardson histological grading system and the complementary value of Ki-67 to this system. Chin Med J (Engl). 2010 Aug 5;123(15):1976-82. PubMed PMID: 20819528.

Yin X, Wu T, Yan Y, Zhang H, Bu H. Treatment for leiomyosarcoma and leiomyoma in children with HIV infection. Cochrane Database Syst Rev. 2010 May 12;(5):CD007665. doi: 10.1002/14651858.CD007665.pub2. Review. PubMed PMID: 20464756.

Wang W, Tang T, Zhang P, Bu H. Postconditioning attenuates renal ischemia-reperfusion injury by preventing DAF down-regulation. J Urol. 2010 Jun;183(6):2424-31. doi: 10.1016/j.juro.2010.01.066. Epub 2010 Apr 18. PubMed PMID: 20403613.

Zhang HY, Ke Q, Zhang Z, Zhang R, Fu J, Chen HJ, Wei B, Bu H. Expression of beta-catenin and estrogen receptor in desmoid-type fibromatosis . Sichuan Da Xue Xue Bao Yi Xue Ban. 2010 Jan;41(1):101-5. Chinese. PubMed PMID: 20369480.

Tu Z, Cohen M, Bu H, Lin F. Tissue distribution and functional analysis of Sushi domain-containing protein 4. Am J Pathol. 2010 May;176(5):2378-84. doi: 10.2353/ajpath.2010.091036. Epub 2010 Mar 26. PubMed PMID: 20348246; PubMed Central PMCID: PMC2861102.

Tu Z, Li Q, Bu H, Lin F. Mesenchymal stem cells inhibit complement activation by secreting factor H. Stem Cells Dev. 2010 Nov;19(11):1803-9. doi: 10.1089/scd.2009.0418. Epub 2010 Aug 1. PubMed PMID: 20163251; PubMed Central PMCID: PMC3136717.

Zhang P, Yu P, Wang W, Zhang L, Li S, Bu H. An effective method for the quantitative detection of porcine endogenous retrovirus in pig tissues. In Vitro Cell Dev Biol Anim. 2010 May;46(5):408-10. doi: 10.1007/s11626-009-9264-8. Epub 2010 Jan 28. PubMed PMID: 20108128.

Shi Y, Tu Z, Bao J, Sun H, Wang W, Luo G, Li S, Li Y, Bu H. Urinary connective tissue growth factor increases far earlier than histopathological damage and functional deterioration in early chronic renal allograft injury. Scand J Urol Nephrol. 2009;43(5):390-9. doi: 10.3109/00365520903142244. PubMed PMID: 19921985.

Cheng L, Ye F, Yang R, Lu X, Shi Y, Fan H, Bu H. Osteoinduction of hydroxyapatite tricalcium phosphate bioceramics in mice with a fractured fibula. Acta Biomater. 2010;6(4):156974.doi: 10.1016/j.actbio.2009.10.050.

Yang Y, Wei B, Zhang Z, Tang Y, Fu J, Liao DY, Li FY, Bu H. Intralaboratory reproducibility of HER2 testing in breast cancer by immunohistochemistry and comparison of results obtained by different assays . Zhonghua Bing Li Xue Za Zhi. 2009 Jan;38(1):2934. Chinese. PubMed PMID: 19489222.

Wang JJ, Ye F, Cheng LJ, Shi YJ, Bao J, Sun HQ, Wang W, Zhang P, Bu H. Osteogenic differentiation of mesenchymal stem cells promoted by overexpression of connective tissue growth factor. J Zhejiang Univ Sci B. 2009 May;10(5):355-67. doi: 10.1631/jzus.B0820252. PubMed PMID: 19434762; PubMed Central PMCID: PMC2676415.

Meng GZ, Zhang HY, Zhang Z, Wei B, Bu H. Myofibroblastic sarcoma vs nodular fasciitis: a comparative study of chromosomal imbalances. Am J Clin Pathol. 2009 May;131(5):7019. doi: 10.1309/AJCPV6H2WSYXLKFB. PubMed PMID: 19369631.

Wang W, Zhang P, Wang J, Bu H. Cyclosporine A aggravates vascular endothelial injury in hyperlipidemic rats by down-regulating decay-accelerating factor. Biochem Biophys Res Commun. 2009 Jan 30;379(1):2731. doi: 10.1016/j.bbrc.2008.11.153. Epub 2008 Dec 12. PubMed PMID: 19070591.

Zhang P, Shi M, Wei Q, Wang K, Li X, Li H, Bu H. Increased expression of connective tissue growth factor in patients with urethral stricture. Tohoku J Exp Med. 2008 Jul;215(3):199206. PubMed PMID: 18648180.

Xu S, Wei B, Zhang H, Qing M, Bu H. Evidence of chromosomal alterations in pure usual ductal hyperplasia as a breast carcinoma precursor. Oncol Rep. 2008 Jun;19(6):1469-75. PubMed PMID: 18497952.

所獲榮譽

2019年9月5日，被人力資源社會保障部、教育部授予“全國模範教師”稱號，享受省部級表彰獎勵獲得者待遇。