基本介紹
- 中文名：梁興國
- 國籍：中國
- 職業：教師
- 畢業院校：天津大學
- 主要成就：在國際學術期刊上發表論文50多篇，其中SCI收錄30餘篇
- 性別：男
人物經歷,研究方向,主講課程,主要貢獻,論文,學術著作,
人物經歷
博士生導師。
1992年7月畢業於天津大學化工學院精細化工專業，獲工學學士學位；
1995年3月獲同專業碩士學位；畢業後留校任助教，講師；
2001年9月畢業於日本東京大學工學研究科化學生命工學系獲工學博士學位；
先後在東京大學先端科學技術研究中心，美國波士頓大學高級生物技術中心做博士後研究；
2006年1月應聘到名古屋大學工學研究科，先後任助教，講師，並於2009年8月評為副教授；
現受聘為中國海洋大學食品科學與工程學院教授，食品分子生物學方向學科帶頭人之一，同時受聘為中國海洋大學“山東省‘萬人計畫’第一層次”特聘教授、“泰山學者”海外特聘教授、“築峰人才工程”崗位第二層次特聘教授。
研究方向
主要從事核酸化學，食品中核酸的定性定量檢測，及核酸在代謝過程中的營養作用等方面教學及研究，博士生導師。
主講課程
講授《核酸化學》、《分子認識化學》、《量子化學》等研究生課程。
主要貢獻
在國際學術期刊上發表論文50多篇，其中SCI收錄30餘篇。申報發明專利5項。
論文
1)Liang X.G.,* Zhou M.G., Mochizuki T., Asanuma H.* Construction of photoresponsive nanodevices by using a novel nanomaterial involving multiple zobenzenes. Nucleic Acids Res. Supplement No.54, 2010, accepted.
2)Ito H., Liang X.G.,* Nishioka H., Asanuma H.* Construction of photoresponsive RNA for photoswitching RNA hybridization. Org. Biomol. Chem. 2010, accepted.
3)Liang X.G.,* Mochizuki T., Fujii T., Kashida H., Asanuma H. Design of a Functional Nanomaterial with Recognition Ability for Constructing Light-Driven Nanodevices. LNCS (Lecture Notes in Computer Science), accepted.
4)Asanuma H.,* Toda T., Murayama K., Liang X.G., Kashida H. Unexpectedly stable artificial duplex from flexible acyclic threoninol. J. Am. Chem. Soc., 2010, accepted.
5)Tanaka F.,* Mochizuki T., Liang X.G., Asanuma H., Tanaka S., Suzuki K., Kitamura S., Nishikawa A., Ui-Tei K., Hagiya M. Robust and photo-controllable DNA capsules using azobenzenes. Nano Lett., 2010, 10, 3560-3565.
6)Hara Y., Fujii T., Kashida H., Sekiguchi K., Liang X.G., Niwa K., Takase T., Yoshida Y., Asanuma H.* Coherent Quenching of a Fluorophore for the Design of a Highly Sensitive In-Stem Molecular Beacon. Angew. Chem. Int. Ed., 2010, 49, 5502-5506.
7)Kashida H., Sekiguchi K., Liang X. G., Asanuma H.* Accumulation of fluorophores into DNA duplexes to mimic the properties of quantum dots. J. Am. Chem. Soc., 2010, 132, 6223-6230.
8)Zhou M.G., Liang, X.G.,* Mochizuki T., Asanuma H.* A lightdriven DNA nanomachine for efficiently photoswitching RNA digestion. Angew. Chem. Int. Ed. 2010, 49, 2167-2170. (Selected as hot paper, reported by Chemistry World (Royal Society of Chemistry Chemistry), Highlighted in Nature 2010, 464, 10.)
9)Liang X.G.,* Wakuda R., Fujioka K., Asanuma H. Photoregulation of DNA transcription by using photoresponsive T7 promoters and clarification of its mechanism. FEBS J., 2010, 277, 1551-1561. (selected as the front cover)
10)Nishioka H., Liang X.G.,* Asanuma H.* Effect of the ortho modification of azobenzene on the photoregulatory efficiency of DNA hybridization and thermal stability of its cis-form. Chem. Eur. J., 2010, 16, 2054-2062.
11)Liang X.G.,* Nishioka H., Mochizuki T., Asanuma H.* An interstrand-wedged duplex composed of alternating DNA base pairs and covalently attached intercalators. J. Mater. Chem. 2010, 20, 575-581.
12)Liang X.G.,* Mochizuki T., Nishioka H., Asanuma H.* Line up base pairs and intercalators one by one in a stable duplex. Nucleic Acids Res. Supplement No.53, 2009, 189-190.
13)Kashida H., Takatsu T., Fujii T., Sekiguchi K., Liang X.G., Niwa K., Takse T., Yoshida Y., Asanuma H.* Instem molecular beacon containing a pseudo base pair of threoninol nucleotides for removal of background emission. Angew. Chem. Int. Ed. 2009, 48, 7044-7047.
14)Liang X.G., Mochizuki T., Asanuma H.* A supraphotoswitch involving sandwiched DNA base pairs and azobenzenes for light-driven nanostructures and nanodevices. Small, 2009, 15, 1761-1768. (Selected as the front cover of issue 15.)
15)Kashida H., Liang X.G., Asanuma H.* Rational design of functional DNA with a nonribose acyclic scaffold. Curr. Org. Chem., 2009, 13, 1065-1084.
16)Liang X.G., Kato T., Asanuma H. * Mechanism of DNA elongation during de novo DNA synthesis. Nucleic Acids Res. Supplement No.52, 2008, 41-412.
17)Liang X.G., Takenaka N., Nishioka H., Asanuma H.* Light driven open/close operation of an azobenzene-modified DNA nano-pincette. Nucleic Acids Res. Supplement No.52, 2008, 697-698.
18)Liang X.G., Fujioka K., Tsuda Y., Wakuda R., Asanuma H.* Construction of a photoswitchable gene for turning on and off gene expression with light irradiation. Nucleic Acids Res. Supplement No.52, 2008, 19-20. 19)Liang X.G.* Nishioka H., Takenaka N., Asanuma H.* Construction of photonsfuelled DNA Nanomachines by Tethering Azobenzenes as Engines. LCNS (Lecture Notes in Computer Science). 2008, 5347, 21-32.
20)Liang X.G., Takenaka N., Nishioka H., Asanuma H.* Molecular design for reversing the photoswitching mode of turning ON and OFF DNA hybridization. Chem. Asian. J. 2008, 3, 553-560.
21)Liang X.G., Nishioka H., Takenaka N., Asanuma H. A DNA nanomachine powered by light irradiation. ChemBioChem. 2008, 9, 702-705.
22)Liang, X. G.; Komiyama, M.; Asanuma, H. Diastereomer Separation of Azobenzene-Tethered Oligodeoxyribonucleotides and Determination of Their Absolute Configurations by Enzymatic Digestion. Nucleosides, Nucleotides & Nucleic Acids 2008, 27, 332-350.
學術著作
1)Liang X.G.， Kato, T. Asanuma, H.* De Novo DNA Synthesis by DNA Polymerase. in “Bacterial DNA, DNA Polymerase and DNA Helicases.” 2009, Nova Science Publishers, Inc. (English).
2)Asanuma H., Liang X.G.* The dynamic photoregulation of DNA. in “Science and Technology of Supramolecule – From Base to Innovation. 2009, New Technology New Science Press. (Japanese).
