梁建英,女,復旦大學藥學院藥物分析學系教授,碩士生導師。共發表科研論文20餘篇。
現任復旦大學藥學院藥物分析學系副主任。
基本介紹
人物經歷,教育經歷,工作經歷,研究方向,主要成就,承擔科研項目,代表論著,
人物經歷
教育經歷
1984.09 – 1988.07 華東理工大學化學系,本科
1988.09 – 1991.07 華東理工大學化學系,碩士
工作經歷
1991.07 – 2002.12 上海醫科大學藥學院,講師
2002.12 – 2015.12 復旦大學藥學院,副教授
2015.12 – 復旦大學藥學院,教授
研究方向
1. 藥物分析新技術
2. 生物樣品前處理技術及新藥質量標準
3. 中藥活性成分篩選新技術
主要成就
承擔科研項目
1.國家自然科學基金面上項目, 螢光仿生膜技術研究中藥活性成分的細胞膜通透性,(90409017)
2.上海市科委中藥現代化項目,中成藥大品種的藥效物質基礎研究,(08DZ1971201)
3.上海市科委科技支撐項目一項,長效抗腫瘤藥物雷公藤紅素的臨床前研究,(14431904900)
4.“重大新藥創製”中的抗愛滋病病毒新藥臨床評價研究技術平台建設子課題五-藥物代謝組研究,(2012ZX09303013-005)
代表論著
1. Li MH; Zhu RR; Song XX; Wang ZJ; Weng HB; Liang JY*(梁建英). A sensitive method for the quantification of short-chain fatty acids by benzyl chloroformate derivatization combined with GC-MS, Analyst, 2020, DOI: 10.1039/D0AN00005A
2.Xue Y, Liang JY*(梁建英).Chinese hamster ovary-sphingomyelin synthase2 biospecific extraction and liquid chromatography with tandem mass spectrometry analysis for the prediction of bioactive components of Rhizoma Polygoni Cuspidati. Journal of Separation Science. 2016, 39, 1067–1072.
3. Ma R, Weng HB, Liang JY *(梁建英). Screening of lipase inhibitors in Folium Mori with lipase-linked magnetic microspheres by high-performance liquid chromatography and evaluation in diabetic mice Journal of Separation Science. 2016, 39, 4474–4483
4. Feng XY, Gao XL, Kang T, Jiang D, Yao JH, Jing YX, Song QX, Jiang XG, Liang JY*(梁建英), Chen J. Mammary-Derived Growth Inhibitor Targeting Peptide-Modified PEG-PLA Nanoparticles for Enhanced Targeted Glioblastoma Therapy. Bioconjugate Chem. 2015, 26, 1850-1861.
5. Deng YC, Liu R, Yang P, Liang JY*(梁建英). Rapid identification of efavirenz metabolites in rats and humans by ultra high performance liquid chromatography combined with quadrupole time-of-flight tandem mass spectrometry. Journal of Separation Science. 2015, 38, 1529–1536.
6. Xue Y, Liang JY*(梁建英). Screening of bioactive compounds in Rhizoma Polygoni Cuspidati with hepatocyte membranes by HPLC and LC-MS. Journal of Separation Science. 2014, 37(3), 250–256.
7. Ren YL, Liu TSh, Song GX, Hu YM, Liang JY *(梁建英). Determination of lomerizine in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study. Journal of Chromatography B. 2014, 947-948, 96–102.
8. Liu JC, Lu Y, Liang, JY*(梁建英). A novel fluorescence derivatization method combined with HPLC for determining the activities of endogenous caspase. Analyst. 2012, 137, 5097–5104.
9. Chen XP, Deng YC, Xue Y, Liang JY*(梁建英). Screening of bioactive compounds in Radix Salviae Miltiorrhizae with liposomes and cell membranes using HPLC. Journal of Pharmaceutical and Biomedical Analysis. 2012, 70, 194-201.
10. Chen XP, Xia YQ, Lu Y, Liang JY* (梁建英). Screening of permeable compounds in Flos Lonicerae Japonicae with liposome using ultrafiltration and HPLC. Journal of Pharmaceutical and Biomedical Analysis 2011, 54, 406-410.
11. Zhou LJ, Chen XP, Gu YQ, Liang JY* (梁建英).Transport Characteristics of Candesartan in Human Intestinal Caco-2 Cell Line, Biopharmaceutics & drug disposition. 2009, 30, 259-264.
12. Zhou LJ, Gu LH, Wang YJ, Liang JY*(梁建英). Determination of bifendate in human by HPLC-MS and bioequivalance on bifendate pills in healthy volunteers ,Journal of Pharmaceutical and Biomedical Analysis. 2006, 40, 1025-1030.