梁廷明,男,博士,南京師範大學副教授。
基本介紹
- 中文名:梁廷明
- 學位/學歷:博士
- 職業:教師
- 專業方向:非編碼RNA(包括miRNA和LncRNA)在代謝性疾病和腫瘤中的調控作用
- 任職院校:南京師範大學
個人經歷,主講課程,研究方向,榮譽獎項,學術成果,
個人經歷
學習及工作經歷:
2016年9月-至今,南京師範大學生命科學學院,副教授
2011年10月-2016年8月,南京師範大學生命科學學院,講師
2006年9月-2011年6月,南京師範大學,生命科學學院,理學博士
1999年9月-2003年6月,信陽師範學院,生命科學學院,理學學士
主要學術兼職:
國際心臟學會中國分會會員;江蘇省發育與細胞生物學會會員
主講課程
主講《細胞生物學》、《現代分子生物學》、《細胞生物學實驗》
研究方向
非編碼RNA(包括miRNA和LncRNA)在代謝性疾病和腫瘤中的調控作用。
榮譽獎項
2016年:南京師範大學“青藍工程”優秀中青年骨幹教師”,2016/01-2018/12
2014年:教育部高等學校科學研究優秀成果獎(科學技術)自然科學獎二等獎(排名第八)
2013年:第二屆江蘇僑界貢獻獎(創新團隊)(排名第六)
2013年:第三屆江蘇省海洋與漁業科技創新獎一等獎(排名第九)
學術成果
主持的科研項目:
1. 國家自然科學基金青年基金項目,2014-2017
2. 江蘇省高校自然科學研究面上項目,2012.8-2014.12
3. 南京師範大學高層次人才科研啟動基金,2013-2016
4. 江蘇省生物學優勢學科II期建設項目(青年教師提升計畫),2015-2017
發表論文列表:
- Guo, L.*,Liang, T.*, microRNAs and their variants in an RNA world: implications for complex interactions and diverse roles in an RNA regulatory network, Brief Bioinform ,2017, doi: 10.1093/bib/bbw124, in press.(Co-Corresponding author)
- Guo, L., Zhang, Q., Ma, X., Wang, J.,Liang, T.*, miRNA and mRNA expression analysis reveals potential sex-biased miRNA expression.2017, Sci Rep, 7, 39812.(Corresponding author)
- Guo, L.,Liang, T., Yu, J., Zou, Q.*,A comprehensive analysis of miRNA/isomiR expression with gender difference, PLoS ONE,2016, 11(5), e0154955.
- Zhang, W., Wang, P., Chen, S., Zhang, Z.,Liang, T.,* and Liu, C.,*. Rhythmic expression of miR-27 targets the clock gene bmal1 through post-transcriptional regulation in the mouse liver.2016, FASEB Journal 30, 2151-2160.(Co-Corresponding author)
- Guo, L.*, Yu, J.,Liang, T.,Zou, Q., miR-isomiRExp: a web-server for the analysis of expression of miRNA at the miRNA/isomiR levels, Sci Rep,2016, 6, 23700. doi:10.1038/srep23700.
- Liang, T., Yu, J., Liu, C., Guo, L.,*. IsomiR expression patterns in Canonical and Dicer-independent miRNAs,2017, Mol Med Rep, 15:1071-1078.
- Liang, T.,Yang, C., Li, P., Liu, C. and Guo, L.,*.Genetic analysis of loop sequences in the let-7 gene family reveal a relationship between loop evolution and multiple isomiRs.2014.PLoS One 9, e113042.
- Liang, T.,Yu, J., Liu, C. and Guo, L.,*.An exploration of evolution, maturation, expression and function relationships in mir-23 - 27 - 24 cluster.2014.PLoS One 9, e106223.
- Liang, T.,*Liu, C. and Ye, Z., Deep sequencing of small RNA repertoires in mice reveals metabolic disorders-associated hepatic miRNAs.2013.PLoS One 8, e80774.(Corresponding author)
- Liang, T.,Guo, L. and Liu, C.,*.Genome-wide analysis of mir-548 gene family reveals evolutionary and functional implications.2012.J Biomed Biotechnol 2012, 679563.
- Liang, T.,Ji, H., Du, J., Ou, J., Li, W., Wu, T., Meng, Q., Gu, W. and Wang, W.,*.Primary culture of hemocytes from Eriocheir sinensis and their immune effects to the novel crustacean pathogen Spiroplasma eriocheiris.2012.Mol Biol Rep 39, 9747-9754. (IF:1.958)
- Liang, T.,Wu, T., Du, J., Ji, H., Li, Y., Gu, W. and Wang, W., Characterization of a tailless white spot syndrome virus from diseasedPenaeus vannameiandProcambarus clarkiiin China.2011. Afr J Biotechnol 10, 13936-13942.
- Liang, T.,Li, X., Du, J., Yao, W., Sun, G., & Dong, X., et al. Identification and isolation of a spiroplasma pathogen from diseased freshwater prawns, macrobrachium rosenbergii , in china: a new freshwater crustacean host.2011.Aquaculture, 318, 1, 1–6.
- Liang, T.,Ji, H., Lian, L., Wu, T., Gu, W., & Wang, W. A rapid assay for simultaneous detection of spiroplasma eriocheiris and white spot syndrome virus in procambarus clarkii by multiplex pcr.2010.Lett Appl Microbiol, 51, 5, 532–538.
- Liang, T.,Qi Feng, Ting Wu, Wei Gu, Wen Wang*. Use of oxytetracycline for the treatment of tremor disease in the Chinese mitten crab (Eriocheir sinensis).2009.Dis Aquat Organ 84:243-250.
- Guo, L.#*, Li, H.#,Liang, T.#, Lu, J., Yang, Q., Ge, Q. and Lu, Z.,*. Consistent isomiR expression patterns and 3' addition events in miRNA gene clusters and families implicate functional and evolutionary relationships.2012.Mol Biol Rep 39, 6699-706.
- Ge, X., Chen, S., Liu, M.,Liang, T., Liu, C. Evodiamine inhibits pdgf‑bb‑induced proliferation of rat vascular smooth muscle cells through the suppression of cell cycle progression and oxidative stress. (2016). Mol Medicine Rep 14:4551-4558
- Ge X, Chen S, Liu M,Liang T, Liu C*, Evodiamine Attenuates PDGF-BB-induced Migration of Rat Vascular Smooth Muscle Cells through Activating PPARγ, 2015. Int J Mol Sci,16(12):28180-28193.
- Chen, S., Ding, Y., Tao, W., Zhang, W.,Liang, T.and Liu, C.,*. Naringenin inhibits TNF-α induced VSMC proliferation and migration via induction of HO-1.2012.Food Chem Toxicol. 50, 3025-3031.
- Chen, S., Qian, J., Shi, X., Gao, T.,Liang, T.and Liu, C.,*. Control of hepatic gluconeogenesis by the promyelocytic leukemia zinc finger protein.2014.Mol Endocrinol. 28, 1987-1998.
- Wang, Z., Zhang, X., Chen, S., Wang, D., Wu, J.,Liang, T.and Liu, C.,*. Lithium chloride inhibits vascular smooth muscle cell proliferation and migration and alleviates injury-induced neointimal hyperplasia via induction of PGC-1alpha.2013.PLoS One 8, e55471.
- Yi, N. #, Chen, S. #, Ma, A., Chen, P., Yao, B.,Liang, T.and Liu, C.,*. Tunicamycin Inhibits PDGF‐BB‐Induced Proliferation and Migration of Vascular Smooth Muscle Cells Through Induction of HO-1.2012.The Anatomical Record 295, 1462-1472.
- Guo, L.,Liang, T.,and Lu, Z.,*. A comprehensive study of multiple mapping and feature selection for correction strategy in the analysis of small RNAs from SOLiD sequencing.2011.Biosystems. 104: 87–93.
- Guo, L.,Liang, T.,Gu, W., Xu, Y., Bai, Y., Lu, Z.,*.2011. Cross-mapping events in miRNAs reveal potential miRNA-mimics and evolutionary implication. PLoS ONE. 6(5): e20517
- Feng, Q., Wu, G.,Liang, T.,Ji, H., Jiang, X., Gu, W., and Wang, W.,*. Pharmacokinetics of oxytetracycline in hemolymph from the Chinese mitten crab,Eriocheir sinensis.2011.J. Vet. Pharmacol. Therap. 34, 51–57.
- Meng, Q., Li, W.,Liang, T.,Jiang, X., Gu, W., Wang, W., *. Identification of adhesin-like protein ALP41 from Spiroplasma eriocheiris and induction immune response ofEriocheir sinensis.2010.Fish Shellfish Immun. 4:578-593.
- Feng, Q., Gao, T., Ji, H., Jiang, X.,Liang, T.,Gu, W., Wu, G., Gao, G., and Wang, W., *. Kinetic analysis of oxytetracycline residues in Chinese mitten crab (Eriocheir sinensis) muscle following intramuscular administration.2010.J Fish Dis, 8: 639-647.
- Wang, J., Huang, H., Feng, Q.,Liang, T.,Bi, K., Gu, W., Wang, W., * and Shields, J., Enzyme-linked immunosorbent assay for the detection of pathogenic spiroplasma in commercially exploited crustaceans from China.2009.Aquaculture. 292:166-171.
- Wang, W. *, Gu, W., Gasparich, G.,Bi, K., Ou, J., Meng, Q.,Liang, T.,Feng, Q., Zhang, J., and Zhang, Y., Spiroplasma eriocheiris sp. nov., a novel species associated with mortalities inEriocheir sinensis, Chinese mitten crab.2010.Int J Syst Evol Microbiol, 61:703-708