基本介紹
- 中文名：李順
- 學位/學歷：博士後
- 性別：男
- 職稱：講師
研究方向,科研項目,論文列表,
研究方向
1.腫瘤細胞力學與腫瘤微環境
2.細胞力學與生物學耦合
科研項目
1. 胞外基質剛度與細胞幾何形態對腫瘤起始細胞表型及粘附行為的協同調控機制研究，國家自然科學基金青年基金項目（11502049）
2. 基質物理特性協同調控腫瘤幹細胞侵襲表型的機制研究，中國博士後科學基金面上項目（2016M592657）
論文列表
已經發表SCI收錄論文10餘篇，代表性論文如下：
01. Xiong N, Li S（共同第一作者）, Tang K, Bai H, Peng Y, Yang H, Wu C, Liu Y*. (2016). Involvement of caveolin-1 in low shear stress-induced breast cancer cell motility and adhesion: roles of FAK/Src and ROCK/p-MLC pathways. BBA-Molecular Cell Research. DOI: 10.1016/j.bbamcr.2016.10.013. (in press)
02. Yang H, Guan L, Li S（共同第一作者）, Jiang Y, Xiong N, Li L, Wu C, Zeng H, Liu Y*. (2016) Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo. Oncotarget. 7(13): 16227-16247.
03. Li S, Lu J, Chen Y, Xiong N, Li L, Zhang J, Yang H, Wu C, Zeng H, Liu Y*. (2016) MCP-1-triggered ERK/GSK-3beta/Snail pathway facilitates epithelial- mesenchymal transition and promotes cell migration of human breast carcinoma MCF-7 cells. Cellular and Molecular Immunology. doi:10.1038/cmi.2015.106
04. Li S, Zhang J, Yang H, Wu C, Dong X, Liu Y*. (2015) Copper depletion inhibits CoCl2-induced aggressive phenotype of MCF-7 cells via downregulation of HIF-1 and inhibition of Snail/Twist-mediated epithelial-mesenchymal transition. Scientific Reports. 5: 12410; DOI: 10.1038/srep12410.
05. Li S, Wang M, Chen X, Li S-F, Li-Ling J, Xie H-Q*. (2014) Inhibition of osteogenic differentiation of mesenchymal stem cells by copper supplementation. Cell Proliferation. 47(1):81-90; DOI: 10.1111/cpr.12083.
06. Li S, Xie Huiqi, Li Shengfu, Kang Y James*. (2012) Copper stimulates growth of human umbilical veinendothelial cells in a vascular endothelial growth factor-independent pathway. Experimental Biology and Medicine. 237(1):77-82; DOI: 10.1258/ebm.2011.011267.
07. Li T, Shen X, Geng Y, Chen Z, Li L, Li S, Yang H, Wu C, Zeng H, Liu Y*. (2016) Folate-functionalized magnetic-mesoporous silica nanoparticles for drug/gene co-delivery to potentiate the antitumor efficacy. ACS Applied Materials & Interfaces. 8: 13748-13758.
08. Li L, Zhang J, Xiong N, Li S, Chen Y, Yang H, Wu C, Zeng H, Liu Y*. (2016) Notch-1 signaling activates NF-κB in human breast carcinoma MDA-MB-231 cells via PP2A-dependent AKT pathway. Med Oncol. 33(4):33; DOI: 10.1007/s12032-016-0747-7.
09. Yang H, Xu M, Li S, Shen X, Li T, Yan J, Zhang C, Wu C, Zeng H, Liu Y*. (2016) Chitosan hybrid nanoparticles as a theranostic platform for targeted doxorubicin/VEGF shRNA co-delivery and dual-modality fluorescence imaging. RSC Advances. 6: 29685-29696.
10. Xie HL, Zhang Y, Huang YZ, Li S, Wu CG, Jiao XFn, Tan MY, Huang YC, Deng L*. (2014) Regulation of high mobility group box 1 and hypoxia in the migration of mesenchymal stem cells. Cell Biol Int. 38(7):892-7; DOI: 10.1002/cbin.10279.
