李維鳳

李維鳳,女,博士,副教授,碩士研究生導師。

基本介紹

  • 中文名:李維鳳
  • 國籍:中國
  • 職業:教師
  • 性別:女
簡介,成就,

簡介

研究領域或方向:
藥物製劑工藝及新劑型設計;
中藥活性物質及作用過程研究。
教育背景:
1986年畢業於西安醫科大學藥學院藥學專業;
2005年獲得西安交通大學藥物分析碩士學位;
2010年獲得西安交通大學藥物分析學博士學位。
學術及科研成果:主持了包括陝西省自然科學基金項目、陝西省中醫管理局基
金項目等6項省部級課題,主持中央高校基本科研業務費專項基金(學科交叉類
科研項目)項目;作為分科負責人承擔了國家高技術研究發展計畫(863計畫)MEMS重大專項,國家自然科學基金,陝西省中醫藥管理局重點科研項目、陝西省科技攻關項目、西安市科委重大創新技術項目、企業合作項目等科研15項。以第一發明人獲得國家發明專利7項。主編2007年由中國醫藥科技出版社出版的國家執業藥師資格考試用書《藥劑學》,參編2000年由世界圖書出版社西安公司出版《最新臨床藥物手冊》、十一五規劃教材《生物藥劑學與藥物動力學》、《藥劑學應試指南》、《藥劑學實驗指導》等。先後發表研究論文40餘篇,以第一作者或通訊作者被SCI收錄14篇。
學術兼職:中國藥學會會員;陝西省藥學會藥劑分會會員;陝西省中醫藥科技開發研究會生物醫藥分會委員。

成就

學術論文(第一作者或通訊作者,總計16篇)
[1] Weifeng Li, Xiaofeng Niu, Ping Zhou, Langchong He. A Combined Peritoneal Macrophage/Cell MembraneChromatography and Offline GC–MS Method for Screening Anti-Inflammatory Components from Chinese Traditional Medicine Houttuynia cordata Thunb. Chromatographia, 2011, 73: 673-680.
[2] Weifeng Li, Ping Zhou, Yanmin Zhang, Langchong He. Houttuynia cordata, a novel and selective COX-2 inhibit with anti-inflammatory activity. Journal of Ethnopharmacology, 2011, 133(2): 922-927.
[3] Weifeng Li, Hongling Yu, Xiaofeng Niu, Yuhai Tang, Langchong He. Determination of 2-Undecanone in Chinese Medicine Houttuynia cordata Thunb by HPLC-CL detection.Journal of Liquid Chromatography & Related Technologies,2011, 35(14): 1431-1441.
[4] Weifeng Li, Ting Fan, Yanmin Zhang, Xiaofeng Niu, Wei Xing.Effect of Chelerythrine Against Endotoxic Shock in Mice and Its Modulation of Inflammatory Mediators in Peritoneal Macrophages Through the Modulation of Mitogen-Activated Protein Kinase (MAPK) Pathway. Inflammation , 2012, 35 ( 6) : 1814-1824.
[5] Weifeng Li, Ting Fan, Yanmin Zhang, Te Fan, Ping Zhou, Xiaofeng Niu, Langchong He. Houttuynia cordata Thunb volatile oil exhibited anti-inflammatory effects in vivo and inhibited nitric oxide and tumor necrosis factor-α production in LPS-stimulated mouse peritoneal macrophages in vitro. Phytotherapy Research, 2012, DOI: 10.1002/ptr.4905.
[6] Weifeng Li, Xiaofeng Niu, Jiye Zhang, Ping Zhou, Langchong He. Determination of 2-Undecanone in Rat Plasma and Tissue by a High Performance Liquid Chromatography Method: An Application for the Pharmacokinetic and Tissue Distribution Research. Journal of Liquid Chromatography & RelatedTechnologies, 2012, DOI:10.1080/10826076.2012.731670.
[7] Weifeng Li, Wei Xing, Xiaofeng Niu, Ping Zhou, Ting Fan. The Pharmacokinetics of Chelerythrine Solution and Chelerythrine Liposomes after Oral Administration to Rats.Planta Medic. 2013, 79(8): 654-660.
[8] Weifeng Li, Huimin Huang, Xiaofeng Niu, Ting Fan, Qingli Mu, Huani Li Protective effect of Tetrahydrocoptisine (THC) against ethanol-induced gastric ulcers in mice. Toxicology and Applied Pharmacology, DOI: 2013. 10.1016/j.taap.2013.05.035.
[9] Weifeng Li, Wei Xing, Sicen Wang, Ting Fan, Huimin Huang, Xiaofeng Niu, Langchong He. An online coupled peritoneal macrophage/cell membrane chromatography and high performance liquid chromatography/mass spectrometry method to screen for anti-inflammatory components from the Chinese traditional medicine Chloranthus multistachys Pei. Biomedical Chromatography,2013.DOI 10.1002/bmc.2963
[10] Weifeng Li, Huimin Huang, Yanmin Zhang, Ting Fan, Xia Liu, Wei Xing, Xiaofeng Niu Anti-inflammatory effects of tetrahydrocoptisine from Corydalis Impatiens is a function of possible inhibition of TNF-α, IL-6 and NO production in lipopolysaccharide (LPS)-stimulated peritoneal macrophages via p38MAPK and ERK 1/2 inactivation. European Journal of Pharmacology, 2012. DOI: 10.1016/j.ejphar.2013.06.017
[11] Xiaofeng Niu, Weifeng Li(通訊作者), Hongbo Xu, Xia Liu, Lin Qi Simultaneous quantification of eleven isoquinoline alkaloids in Corydalis impa­tiens (Pall.) Fisch by a high-performance liquid chromatogra­phy. Journal of Separation Science, 2013, DOI: 10.1002/jssc.201300036.
[12] Xiaofeng Niu, Ting Fan, Weifeng Li(通訊作者), Huimin Huang, Yanmin Zhang, Wei Xing Protective effect of sanguinarine against acetic acid induced ulcerative colitis in mice. Toxicology and Applied Pharmacology,2013, 267: 256-265
[13] Xiaofeng Niu, Ping Zhou, Weifeng Li(通訊作者),Hong-Bo Xu. Effects of chelerythrine, a specific inhibitor of cyclooxygenase-2, on acute inflammation in mice. Fitoterapia, 2011, 82(4): 620-625.
[14] Xiaofeng Niu, Lin Qi, Weifeng Li(通訊作者), Xia Liu . Simultaneous analysis of eight phenolic compounds in Phyllanthus simplex Retz by HPLC-DAD-ESI/MS. Journal of Medicinal Plants Research, 2012, 6(9): 1512-1518.
[15] Xiaofeng Niu , Ting Fan,Weifeng Li(通訊作者),Wei Xing, Huimin Huang. The Anti-inflammatory Effects of Sanguinarine and Its Modulation of Inflammatory Mediators from Peritoneal Macrophages, European Journal of Pharmacology, 2012, 689(1-3):262-269
[16] Xiaofeng Niu, Wei Xing, Weifeng Li(通訊作者), Ting Fan, Hua Hu, Yongmei Li. Isofraxidin Exhibited Anti-inflammatory Effects in Vivo and Inhibited TNF-α Production in LPS-induced Mouse Peritoneal Macrophages in Vitro via the MAPK Pathway. International Immunopharmacology,2012, 14:164-171.

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