李曉娟,教授,博士生導師,國家優秀青年科學基金獲得者。2012年畢業於中國科學院植物研究所,獲博士學位;2012年7月起在北京林業大學生物科學與技術學院工作。主要圍繞“樹木優良性狀形成的生物基礎”,建立了活細胞單分子動態研究和林木分子設計育種技術,挖掘和鑑定了調控樹木再生和發育的關鍵基因,揭示了調控樹木維管形成層發育的分子細胞學機制。研究成果發表在Nature Protocols,Trends in Plant Science, Molecular Plant, The Plant Cell等國際知名學術期刊,授權多項國家發明專利。主持國家優青項目、重大研究計畫重點項目、國家自然基金面上項目多項。擔任中國植物生理與植物分子生物學學會青年工作委員會委員,中國林學會樹木生理生化專業委員會常務委員等。
基本介紹
- 中文名:李曉娟
- 國籍:中國
- 民族:漢
- 畢業院校: 中科院植物研究所
- 職業:教師
- 學位:博士
研究方向,承擔項目,所獲榮譽,發表文章,
研究方向
植物細胞生物學
承擔項目
國家自然科學基金, 細胞器互作網路及其功能研究重大研究計畫重點項目, 植物內質網-質膜互作動態及其調控內質網脅迫抗性的機制,233 萬元,主持
國家自然科學基金,優秀青年基金項目,植物細胞生物學,130萬元,主持
國家自然科學基金,面上項目,胞內轉運參與膜結合轉錄因子AtCLB回響逆境脅迫的單分子研究,60 萬元,主持
國家自然科學基金,面上項目,套用單分子技術研究細胞膜微區調節水通道蛋白活性的機制, 82萬元,主持
北京林業大學“傑出青年人才”培育計畫項目,100 萬元,主持
所獲榮譽
2018年 獲得北京林業大學第十四屆青年教師教學基本功比賽三等獎
2012年 獲得中國科學院院長優秀獎
2013年 獲得北京大學第七屆實驗技術成果獎校級二等獎
發表文章
- Jiahui Bian, Xiao Su, Xiaoyan Yuan, Yuan Zhang, Jinxing Lin, Xiaojuan Li*. 2023. ER-membrane contact sites: cross talk between Membrane-bound organelles in plant cells. Journal of Experimental Botany doi.org/10.1093/jxb/erad068
- Yaning Cui, Xi Zhang1, Xiaojuan Li, Jinxing Lin*. 2023. Multiscale microscopy to decipher plant cell structure and dynamics. New Phytologist 237:1980-1997.
- Mingyang Li, Yuan Zhang; Changyuan Li; Jinxing Lin; Xiaojuan Li*. 2022 Polyvinyl chloride nanoparticles affect cell membrane integrity by disturbing the properties of the multicomponent lipid bilayer in Arabidopsis thaliana. Molecules 27:5906
- Yuan Zhang, Yuqing Lu, Hafez El Sayyed, Jiahui Bian, Jinxing Lin, Xiaojuan Li*, 2022. Transcription factor dynamics in plants: Insights and technologies for in vivo imaging. Plant Physiology 189:23-36
- Pawan Kumar Jewaria, Meng Yu, Xiaojuan Li*. 2021. Cell wall and hormone interplay controls growth asymmetry. Trends in Plant Science 26:665-667
- Yaning Cui, Yanxia Zhao, Yuqing Lu, Xiao Su, Yingying Chen, Yingbai Shen, Jinxing Lin, Xiaojuan Li*. 2021. In vivo single-particle tracking of the aquaporin AtPIP2;1 in stomata reveals cell type-specific dynamics. Plant Physiology 185:1666-1681
- Pawan Kumar Jewaria, Heikki Hänninen, Xiaojuan Li, Rishikesh P. Bhalerao*,Rui Zhang*. 2021. A hundred years after: endodormancy and the chilling requirement in subtropical trees. New Phytologist 231: 565–570
- Xi Zhang, Zijian Hu, Yayu Guo, Xiaoyi Shan, Xiaojuan Li, Jinxing Lin*. 2020 High-efficiency procedure to characterize, segment, and quantify complex multicellularity in raw micrographs in plants. Plant Methods 16:100
- Jingjing Xing, Xiaojuan Li (Co-first author), Xiaohua Wang, Xueqin Lv, Li Wang, Liang Zhang, Yingfang Zhu, Qianhua Shen, František Baluška, Jozef Šamaj, Jinxing Lin*. 2019. Secretion of Phospholipase Dδ functions as a novel regulatory mechanism in plant innate immunity. Plant Cell 31: 3015–3032
- Yaning Cui, Meng Yu, Xiaomin Yao, Jingjing Xing, Jinxing Lin, Xiaojuan Li*. 2018. Single-particle tracking for the quantification of membrane protein dynamics in living plant cells. Molecular Plant 11:1315-1327
- Yaning Cui, Xiaojuan Li (Co-first author), Meng Yu, Ruili Li, Lusheng Fan, Yingfang Zhu, Jinxing Lin. 2018. Sterols regulate endocytic pathways during flg22-induced defense responses in Arabidopsis. Development doi: 10.1242/dev.165688
- Xiaojuan Li, Jingjing Xing, Zongbo Qiu, Qihua He, Jinxing Lin*. 2016. Quantification of membrane protein dynamics and interactions in plant cells by fluorescence correlation spectroscopy. Molecular Plant 9: 1229-1239.
- Hongyang Wu, Huimin Xu, Hanyin Li, Dongmei Wei, Jinxing Lin, Xiaojuan Li*. 2016. Seasonal development of cambial activity in relation to xylem formation in Chinese fir. Journal of Plant Physiology. 195:23-30.
- Yuanyuan Zhao, Sen Lin, Zongbo Qiu, Dechang Cao, Jialong Wen, Xin Deng, Xiaohua Wang, Jinxing Lin, Xiaojuan Li*. 2015. MicroRNA857 is involved in the regulation of secondary growth of vascular tissues in Arabidopsis. Plant Physiology 169:2539-2552.
- Xiaohua Wang, Xiaojuan Li (Co-first author), Xin Deng, Doan-Trung Luu, Christophe Maurel, Jinxing Lin*. 2015. Single-molecule fluorescence imaging to quantify membrane protein dynamics and oligomerization in living plant cells. Nature Protocols 10:2054–2063.
- Zongbo Qiu, Xiaojuan Li (Co-first author), Yuanyuan Zhao, Manman Zhang, Yinglang Wan, Dechang Cao, Shanfa Lu, Jinxing Lin*. 2015. Genome-wide analysis reveals dynamic changes in expression of microRNAs during vascular cambium development in Chinese fir, Cunninghamia lanceolata. Journal of Experimental Botany 66:3041–3054.
- Yaning Cui, Yu Ling, Junhui Zhou, Xiaojuan Li*. 2015. Interference of the histone deacetylase inhibits pollen germination and pollen tube growth in Picea wilsonii Mast. PLOS ONE 10(12): e0145661.
- Xiaojuan Li, Doan-Trung Luu, Christophe Maurel, Jinxing Lin*. 2013. Probing plasma membrane dynamics at the single-molecule level. Trends in Plant Science 18:617-624.
- Xiaojuan Li, Xiaohua Wang, Yong Yang, Ruili Li, Qihua He, Xiaohong Fang, Doan-Trung Luu, Christophe Maurel, Jinxing Lin*. 2011. Single-molecule analysis of PIP2;1 dynamics and partitioning reveals multiple modes of Arabidopsis plasma membrane aquaporin regulation. Plant Cell 23: 3780-3897.
- Huaiqing Hao, Lusheng Fan, Tong Chen, Ruili Li, Xiaojuan Li, Qihua He, Miguel A. Botella, Jinxing Lin*. 2014. Clathrin and membrane microdomains cooperatively regulate Rbohd dynamics and activity in Arabidopsis. Plant Cell 26:1729-1745.
- 張耿,邊佳輝,崔亞寧,李曉娟2021. DNA/RNA甲基化修飾檢測技術進展. 電子顯微學報. 40:348-359
- 劉佩佩,張耿,李曉娟 2021. 植物果膠的生物合成與功能. 植物學報 56:191-200
- 崔亞寧,錢虹萍,趙艷霞,李曉娟 2020. 模式識別受體的胞內轉運及其在植物免疫中的作用. 植物學報 55:1-11
- 曲紹峰,林金星,李曉娟* 2014. FCS/FCCS技術及其在植物細胞生物學中的套用. 電子顯微學報 33:461-468.
- 崔亞寧,凌宇,李曉娟* 2016. GABA 合成抑制劑對花粉管生長過程中線粒體活動及 ROS 分布的影響. 電子顯微學報 35:139-145
- 張原,張雪萍,張月倩,李曉娟 2021. 單分子螢光檢測技術的發展及其在植物生物學研究中的套用. 生物技術通報 10.13560/j.cnki.biotech.bull.1985.2021-0793
- 魯雨晴,崔亞寧,張原,姚小敏,李曉娟2020. 植物水通道蛋白PIPs亞細胞定位轉運的研究進展. 電子顯微學報 39:779-786