李娟(四川大學生命科學院教授)

李娟，女，香港大學博士，四川大學生命科學院教授，碩士生導師。

基本介紹

• 中文名：李娟
• 國籍：中國
• 畢業院校：香港大學
• 學位/學歷：博士
• 職務：四川大學碩士生導師
• 職稱：教授

人物經歷

1990-1994：四川大學，理學學士
1994-1997：四川大學，理學碩士
1997-1999：成都生物製品研究所，實習研究員
1999-2003：香港大學動物學系，理學博士
2004-2006：香港大學動物學系, 博士後
2006-現在：四川大學生命科學學院講師，副教授，教授

研究內容

1，家雞卵泡發育進程中重要基因功能鑑定與表達調控機制解析

2，腸道微生物代謝產物對動物生長發育的影響

學術成果

1 Mo C, Cai G, Huang L, Deng Q, Lin D, Cui L, Wang Y, Li Juan* （2015）Corticotropin-releasing Hormone (CRH) Stimulates Cocaine- and amphetamine-regulated Transcript Gene (CART1) Expression through CRH Type 1 Receptor (CRHR1) in Chicken Anterior Pituitary. Mol Cell Endocrinol. 417：166-177 (*通訊作者)

2 Cai G, Mo C, Huang L, Li Juan*, Wang Y*（2015）Characterization of the Two CART Genes (CART1 and CART2) in Chickens (Gallus gallus). PLoS One. 18;10(5):e0127107. (*通訊作者)

3 Li X, Fang W, Hu Y, Wang Y, Li Juan* （2015）Characterization of fibronectin type III domain-containing protein 5 (FNDC5) gene in chickens: Cloning, tissue expression, and regulation of its expression in the muscle by fasting and cold exposure.Gene. 10;570(2):221-9. (*通訊作者)

4 Zhang J, Cheng S, Wang Y, Yu X, Li Juan* (2014) Identification and characterization of the free fatty acid receptor 2 (FFA2) and a novel functional FFA2-like receptor (FFA2L) for short-chain fatty acids in pigs: Evidence for the existence of a duplicated FFA2 gene (FFA2L) in some mammalian species. Domestic Animal Endocrinology 47:108-118 (*通訊作者)

5 Mo C, Zhong Y, Wang Y, Yan Z, Li Juan* (2014) Characterization of glucagon-like peptide 2 receptor (GLP2R) gene in chickens: functional analysis, tissue distribution, and developmental expression profile of GLP2R in embryonic intestine. Domestic Animal Endocrinology 48:1-6 (*通訊作者)

6 He X, Meng F, Wang Y, Li Juan* (2014) Molecular Cloning and Characterization of Two Pig Vasoactive Intestinal Polypeptide Receptors (VPAC1-R and VPAC2-R). DNA Cell Biol. 33:259-270 (*通訊作者)

7 Li Juan*, Meng F, Song C, Wang Y, Leung FC* (2012) Characterization of chicken visfatin gene: cDNA cloning, Tissue expression, and promoter analysis. Poultry Science 91: 2885-94 (*通訊作者)

8 Huang G, Li Juan*, Fu H, Yan Z, Bu G, He X, Wang Y* (2012) Characterization of glucagon-like peptide 1 receptor (GLP1R) gene in chickens: functional analysis, tissue distribution, and identification of its transcript variants. Domestic Animal Endocrinology 43: 1-15 (*通訊作者)

9 Wang Y, Huang G, Li Juan, Meng F, He X. Leung F.C* (2012) Characterization of Chicken Secretin (SCT) and Secretin Receptor (SCTR) Genes: A Novel Secretin-like Peptide (SCT-LP) and Secretin Encoded in a Single Gene. Molecular and Cellular Endocrinology, 348: 270-280 (*通訊作者)

10 Yao Meng, Shuangfeng Liu, Juan Li, Yanfa Meng, Xiaojun Zhao* (2012) Preparation of an antitumor and antivirus agent: chemical modification of α-MMC and MAP30 from Momordica Charantia L. with covalent conjugation of polyethyelene glycol Int J Nanomedicine. 7: 3133–3142. (*通訊作者)

11. Wang Y*, Huang G, Li Juan, Meng F, He X. Leung F.C* (2012) Characterization of Chicken Secretin (SCT) and Secretin Receptor (SCTR) Genes: A Novel Secretin-like Peptide (SCT-LP) and Secretin Encoded in a Single Gene. Molecular and Cellular Endocrinology 348: 270-280 (*通訊作者).

12 Wang Y, Li Juan, Kwok AHY, Ge W & Lueng FC* (2010) A novel prolactin-like protein (PRL-L) gene in chickens and zebrafish: Cloning and Characterization of its tissue expression. General and Comparative endocrinology 166: 200-210. (*通訊作者)

13 Wang Y, Li Juan, C. Wang CY, Kwok AHY, Zhang X & Leung FC(2010) Characterization of the receptors for chicken GHRH and GHRH-related peptides: Identification of a novel receptor for GHRH and the receptor for GHRH-LP (PRP). Domestic Animal Endocrinology 38: 13-31. (*通訊作者)

14 Wang J, Wang Y, Li X, Li Juan* and Leung FC* (2008) Cloning, tissue distribution and functional characterization of chicken glucagon receptor. Poultry Science 87：2678-2688 (*通訊作者)

15 Wang Y, Li Juan, Wang CY, Kwok AHY, Leung FC* (2007) Identification of the endogenous ligands for chicken growth hormone-releasing hormone (GHRH) receptor. Evidence for a separate gene encoding GHRH in submammalian vertebrates. Endocrinology 148: 2405-2416 (*通訊作者)

16 Wang Y, Li Juan，Wang CY, Kwok AHY, Leung FC* (2007) Epidermal growth factor receptor (EGFR) ligand in the chicken ovary: I) Evidence for heparin binding epidermal growth factor-like growth factor (HB-EGF) as a potential oocyte-derived factor to control granulosa cell proliferation and HB-EGF and Kit ligand expression. Endocrinology 148: 3426 – 3440. (*通訊作者)

17 Wang Y, Wang Z, Li Juan, Wang Y*, Leung FC* (2007) A database for chicken full-length cDNAs. Physiological Genomics 28:141-5, (*通訊作者)

18 Li Juan, Wang X, and Leung FC* (2007) The intragenomic polymorphism of a partially inverted repeat (PIR) in Gallus gallus domesticus, potential role of inverted repeats in satellite DNAs evolution. Gene 387:118-125. (*通訊作者)

19 Li Juan and Leung FC *(2006) A CR1 element is embedded in a novel tandem repeat (HinfI repeat) within the chicken genome. Genome 49:97-103. (*通訊作者)

20 Wang CY, Wang Y, Li Juan and Leung FC* (2006) Expression profiles of growth hormone-releasing hormone and growth hormone-releasing hormone receptor during chicken embryonic pituitary development. Poultry Science 85:569-576. (*通訊作者)

21 Wang X, Li Juan and Leung FC* (2002) Partially inverted tandem repeat isolated from pericentric region of chicken chromosome 8. Chromosome Res 10:73-82. (*通訊作者)

22 Li Juan, Wang X and Leung FC* (2002) Partially inverted repetitive satellite DNA: A potential indicator for genetic homozygosity in chicken. 7th World Congress on Genetics Applied to Livestock Production 33:113-115.

項目支持

國家自然科學基金；四川省套用基礎研究基金；成都市套用基礎研究基金

獲獎記錄

第七屆大學生《挑戰杯》課外學術活動競賽：代表香港大學獲特等獎

2008，2011，2012年度四川大學青年骨幹教師獎

《精品開放課程建設突出貢獻獎》（細胞生物學課程組，排名第三）