曾驥，博士，廣東工業大學青年百人計畫A+引進人才。曾任職麻省理工學院合成生物學中心博士後及哈佛大學醫學院研究員。主要研究方向包括合成生物學原件開發及基因線路設計、病原菌與宿主的相互作用及創新治療等。研究成果先後在Nature Communications，ACS Synthetic Biology，Cell Host & Microbes等本領域國際頂尖和主流期刊上發表。
基本介紹
人物經歷,主要成就,社會任職,
人物經歷
2021.09 - 今 廣東工業大學 生物醫藥學院 教授 青百A+引進人才
2018.09 - 2021.04 哈佛大學醫學院 波士頓兒童醫院 研究員
2014.01 - 2018.08 麻省理工學院 合成生物學中心 博士後
2007.09 - 2013.12 德克薩斯大學 細胞及分子生物學 博士
主要成就
1. Ji Zeng, Jonathan Teo, Areen Banerjee, Timothy W. Chapman, Jaewook Kim, and Rahul Sarpeshkar,A synthetic microbial operational amplifier, ACS Synth. Biol., 2018, 7(9), pp2007–2013
2. Peng Chen, Ji Zeng, （共同第一作者）Zheng Liu, Siyu Wang, Songhai Tian, Liang Tao, Hatim Thaker, Li Xing, Craig B. Gutierrez, Ralf Gerhard, Lan Huang, Min Dong*, Rongsheng Jin*, Structural basis for CSPG4 as a key receptor and therapeutic target for C. difficile toxin B, Nature Communications, 2021 June, 12(1):3748, Equally contributed
3. Ji Zeng, and Stephen Spiro, Finely-tuned regulation of the aromatic amine degradation pathway in Escherichia coli, Journal of Bacteriology, 2013 Nov; 195(22):5141-50
4. Ji Zeng; Areen Banerjee; Jaewook Kim; Yijie Deng, Tim W. Chapman, Ramez Daniel; Rahul Sarpeshkar, A Novel Bioelectronic Reporter System in Living Cells Tested with a Synthetic Biological Comparator, Sci Rep. 2019 May 13;9(1):7275. Equally contributed
5. Michael J. Mansfield, Benjamin J-M Tremblay, Ji Zeng, Xin Wei, Min Dong, Andrew C. Doxey, Classification and evolution of Clostridium difficile toxins from analysis of 6500+ genomes, PLOS Pathogens, 2020 Dec 28;16(12):e1009181, Equally contributed
6. Songhai Tian, Yang Liu, Hao Wu, Hao Liu, Ji Zeng, Mei Yuk Choi, Hong Chen, Ralf Gerhard, and Min Dong, Genome-wide CRISPR screen identifies semaphorin 6A and 6B as receptors for Paeniclostridium sordellii toxin TcsL, Cell Host & Microbe, Cell Host Microbe. 2020 Apr 4. pii: S1931-3128(20)30171-2.
7. Zheng Liu, Sicai Zhang, Peng Chen, Songhai Tian, Ji Zeng, Kay Perry, Min Dong, and Rongsheng Jin*, Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B, Science Advances, 22 Oct 2021, 7(43), DOI: 10.1126/sciadv.abi4582
社會任職
1.中國醫藥生物技術協會合成生物技術分會第一屆委員會委員
2.美國微生物學會(American Society for Microbiology，ASM)會員
3.廣東省自然科學基金項目評審專家
