曲衛敏

曲衛敏

曲衛敏，復旦大學基礎醫學院藥理學系教授、博導。

基本介紹

  • 中文名：曲衛敏
  • 畢業院校：日本大阪生命科學研究所
  • 學位/學歷：博士後
  • 職業：教師
  • 專業方向：神經精神藥理學、睡眠與失眠的分子機制、開發鎮靜催眠藥物
  • 就職院校：復旦大學基礎醫學院藥理學系
個人經歷,研究方向,學術成果,

個人經歷

1986和1989年分別獲醫學學士、碩士學位。2000年在日本獲醫學博士學位。
2000-2008年，日本大阪生命科學研究所博士後；日本文部省學術振興會（JSPS）特別研究員。
2008年，作為引進人才進入復旦大學。

研究方向

神經精神藥理學、睡眠與失眠的分子機制、開發鎮靜催眠藥物。

學術成果

主持國家自然基金面上項目、國際合作項目、國家基礎研究重大項目973、上海市科委科技攻關重點項目和浦江人才計畫等項目。共發表SCI論文60餘篇，包括Nat Neurosci, Light Sci & Appl,PNAS,J Neurosci, Neuropsychopharmacology, Br J Pharmacol等
  1. 1.Zhang Z#, Wang HJ#, Wang DR,Qu WM*, Huang ZL*. Red light at intensities above 10 lx alters sleep-wake behavior in mice.Light Science & Applications. 2017, 6, e16231. (IF: 14.098)
  2. 2. Wang YQ#, Li R#, Wang DR#, Cherasse Y, Zhang Z, Zhang MQ, Lavielle O, McEown K, Schiffmann SN, de Kerchove d'Exaerde A,Qu WM*, Lazarus M*, Huang ZL*. Adenosine A2A receptors in the olfactory bulb suppress rapid eye movement sleep in rodents.Brain Struct Funct. 2017, 222(3):1351-1366. (IF: 4.698)
  3. 3. Fang T, Dong H, Xu XH, Yuan XS, Chen ZK, Chen JF,Qu WM*, Huang ZL*. Adenosine A2A receptor mediates hypnotic effects of ethanol in mice.Sci Rep. 2017, 7(1):12678. (IF: 4.259)
  4. 4. Zhang BJ, Shao SR, Aritake K, Takeuchi A, Urade Y, Huang ZL, Lazarus M*,Qu WM*. Interleukin-1β induces sleep independent of prostaglandin D2 in rats and mice.Neuroscience2017, 340:258-267. (IF: 3.277)
5. Zhang BJ, Huang ZL, Chen J-F, Urade Y*,Qu WM*. Adenosine A2A receptor deficiency attenuates the somnogenic effect of prostaglandin D2.Acta Pharmacologica Sinica.2017, 38(4): 469–476. (IF: 3.223)
6. Yuan XS, Wang L, Dong H,Qu WM, Yang SR, Cherasse Y, Lazarus M, Schiffmann SN, d'Exaerde AK, Li RX*, Huang ZL*. Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus. Elife. 2017, 6. pii: e29055. (IF: 7.725)
7. Chen L, Yin D, Wang TX, Guo W, Dong H, Xu Q, Luo YJ, Cherasse Y, Lazarus M, Qiu ZL, Lu J,Qu WM*, Huang ZL*. Basal Forebrain Cholinergic Neurons Primarily Contribute to Inhibition of Electroencephalogram Delta Activity, Rather than Inducing Behavioral Wakefulness in Mice. Neuropsychopharmacology. 2016, 41(8):2133-2146. (IF: 7.048)
  1. 8.Chen CR, Sun Y, Luo YJ, Zhao X, Chen JF, Yanagawa Y,Qu WM*, Huang ZL*. Paeoniflorin Promotes Non-rapid Eye Movement Sleep via Adenosine A1 Receptors.J Pharmacol Exp Ther.2016, 356(1):64-73. (IF: 3.972)
  2. 9.Wang YQ*, Li R, Wu X, Zhu F, Takata Y, Zhang Z, Zhang MQ, Li SQ*,Qu WM*. Fasting activated histaminergic neurons and enhanced arousal effect of caffeine in mice.Pharmacol Biochem Behav2015, 133:164-173. (IF: 2.82)
  3. 10.Xu XH, Qiu MH, Dong H,Qu WM*,Urade Y, Huang ZL*, GABA transporter-1 inhibitor NO-711 alters the EEG power spectra and increases non-rapid eye movement sleep during the active phase in mice.Eur Neuropsychopharmacol,2014, 24(4):585-594. (IF: 5.395)
  4. 11.Liu YY§, Yin D§, Chen L,Qu WM*, Laudon M, Cheng NN, Urade Y, Huang ZL*.Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain.Psychopharmacology,2014, 231(20): 3973-3985. (IF: 4.061)
  5. 12.Wang Q, Yue XF,Qu WM*, Tan R, Zheng P, Urade Y and Huang ZL*, Morphine inhibits sleep-promoting neurons in the ventrolateral preoptic area via mu receptors and induces wakefulness in rats,Neuropsychopharmacology, 2013; 38(5):791-801. (IF: 8.678)
  6. 13.Qu WM*,Yue XF,Sun Y, Fan K, Chen CR, Hou YP, Urade Y, Huang ZL*. Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABA(A) receptor in mice.Br J Pharmacol.2012, 2012, 167(3): 587-596. （IF: 4.92）
  7. 14.Wang YQ, Tu ZC, Xu XY,Qu WM*, Urade Y, Huang ZL*. Acute administration of fluoxetine normalizes rapid eye movement sleep abnormality, but not depressive behaviors in olfactory bulbectomized rats.J Neurochem,2012, 120(2):314-324. (IF: 4.34)
  8. 15.Chen CR, Zhou XZ, Luo YJ, Huang ZL*, Urade Y, Qu WM*.Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, induces sleep via the benzodiazepine site of GABAAreceptor in mice.Neuropharmacology, 2012, 63(6): 1191-1199. (IF: 4.814)
  9. 16.Qu WM, Xu XH, Yan MM, Wang YQ, Urade Y, Huang ZL*. Essential role of dopamine D2 receptor in the maintenance of wakefulness, but not in homeostatic regulation of sleep, in mice.J Neurosci2010, 30(12):4382– 4389. (IF: 7.49)
  10. 17.Qu WM, Huang ZL, Xu XH, Matsumoto N, Urade Y. Dopaminergic D1 and D2 receptors are essential for the arousal effect of modafinil.J Neurosci2008, 28(34):8462-9. （IF: 7.49）
  11. 18.Qu WM,Huang ZL, Xu XH, Aritake K, Eguchi N, Nambu F, et al. Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep.Proc Natl Acad Sci USA2006, 103(47):17949-54. (IF: 9.598)。

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