彭纓 女,1972年6月9日生於吉林長春市,教授,博士生導師。主要研究方向:藥物代謝 中藥物質基礎及質量控制研究,小分子化合物的質譜裂解規律研究。
基本介紹
主要經歷,科研情況,教學情況,論文著作,
主要經歷
彭纓教授畢業於瀋陽藥科大學英語藥學專業,並於2001年獲得碩士學位,2008年獲得博士學位,2007年-2008年在日本名城大學藥學部學習。2012年與鄭江教授組建藥物代謝藥物毒理及藥物設計中美合作研究室。先後任講師、副教授,2016年晉升為教授。
科研情況
彭纓教授長期從事多學科交叉的科學研究,包括:分析化學、藥物代謝學、酶學、毒理學、細胞生物學和分子生物學及免疫化學等。至今共主持參加科研項目20餘項,其中包括國家十一五重大專項、國家自然科學基金等。並任《瀋陽藥科大學學報》外審專家。近年發表論文82篇,SCI收載51篇,其中第一作者和通訊作者41篇,其研究成果發表在多學科領域最權威的學術期刊上,例如:《Archive of Toxicology》(毒理學)、《Chemical Research in Toxicology》(毒理化學)、《Drug Metabolism and Disposition》(藥物代謝學)、《Analytical Chemistry》(分析化學)等。主編論著4部,獲得授權專利3項。本課題組成立至今縱向課題經費達200餘萬元。彭纓教授曾獲得遼寧省科技進步二等獎、遼寧省教學成果二等和三等獎、瀋陽市科技進步一等獎以及瀋陽藥科大學優秀教師等稱號。
教學情況
講授本科生課程:化學分析,儀器分析,科技英語
論文著作
1. Optimization of thermosensitive chitosan hydrogels for the sustained delivery of venlafaxine hydrochloride, International journal of pharmaceutics, 2013,441(1-2):482-49.(IF=3.785)(第一作者)
2. Antioxidant and anti-inflammatory neolignans from the seeds of hawthorn, Bioorganic&Medicinal ChemistryLetters,2016(26):5501-5506. (IF=2.486)(第一作者)
3. Metabolism studies of benzbromarone in rats by high performance liquid chromatography–quadrupole time of flight mass spectrometry, Journal of ChromatographyB 2012,911:122-132.(IF=2.487)(第一作者)
4. Metabolic activation of the furan moiety makes diosbulbin B hepatotoxic, Archives of Toxicology, 2016,90(4):863-872.(IF=6.637)(通訊作者)
5. Selective and Sensitive Platform for Function-Based Screening of Potentially Harmful Furans, Analytical Chemistry,2014,86(21):10755-10762.(IF=5.825)(通訊作者)
6. Detection of cysteine- and lysine-based protein adductions by reactive metabolites of 2,5-dimethylfuran, Analytica Chimica Acta,2015, 896: 93-101.(IF=4.513)(通訊作者)
7. In vitro and in vivo studies of metabolic activation of 8-epidiosbulbin E acetate, Chemical Research in Toxicology, 2015, 28:1737-1746.(IF=3.529)(通訊作者)
8. N-Acetyl lysine/glutathione-derived pyrroles as potential ex vivo biomarkers of bioactivated furan-containing compounds, Chemical Research in Toxicology, 2015,226:23-29.(IF=3.529)(通訊作者)
9. Lysine- and Cysteine-based Protein Adductions Derived from Toxic Metabolites of 8-Epidiosbulbin E Acetate, Toxicol Lett, 2016,264:20-28.(IF=3.522)(通訊作者)
10. Imperatorin is a mechanism-based inactivator of CYP2B6, Drug Metabolism and Disposition, 2015,43:82-88.(IF=3.252)(通訊作者)
11. Identification of Epoxide-Derived Metabolite(s) of Benzbromarone, Drug Metabolism and Disposition,2016,44:607-615.(IF=3.210)(通訊作者)
12. Detection of protein adduction derived from dauricine by alkaline permethylation, Anal Bioanal Chem,2016,408(15):4111-4119.(IF=3.125)(通訊作者)
13. Cysteine-based Protein Adduction by Epoxide-Derived Metabolite(s) of Benzbromarone, Chemical Research In Toxicology, 2016 19;29(12):2145-2152.(IF=3.025)(通訊作者)
14. Cytochrome P450 Mediated Bioactivation of Saracatinib, Chemical Research In Toxicology,2016,21; 29(11):1835-1842.(IF=3.025)(通訊作者)
15. Lysine Adduction by Reactive Metabolite(s) of Monocrotaline, Chemical Research in Toxicology, 2016,29:333-341.(IF=3.025)(通訊作者)