張業旺

張業旺,男,1974年10月生於湖北十堰,博士,江蘇大學藥學院教授,碩士生導師,江蘇大學天智綠業藥物研究所所長。

基本介紹

  • 中文名:張業旺
  • 國籍中國
  • 出生日期:1974年10月
  • 畢業院校:華東理工大學
  • 學位/學歷:博士
  • 職業:教師
  • 專業方向:生物化工
  • 任職院校:江蘇大學
個人經歷,教育經歷,工作經歷,學術兼職,研究方向,學術成果,

個人經歷

教育經歷

2002.09-2006.03,華東理工大學,博士,生物化工。
1997.09-2000.06,大連理工大學,碩士,生物化工。
1993.09-1997.06,武漢工程大學,學士,有機化工。

工作經歷

2015.07至今,教授,江蘇大學
2008.09-2010.08,Postdoc,Assistant professor,Konkuk University, 韓國
2006.06-2015.07,講師,副教授,江蘇大學
2000.06-2002.08,研發工程師,石家莊製藥集團

學術兼職

擔任Journal of Microbiology and Biotechnology (IF2017=1.65)的編委(Editorial Board)。
擔任Chemical Engineering Journal, ACS Applied Materials & Interfaces, Bioresource Technology, Materials Science & Engineering C, Applied Surface Science, International Journal of Biological Macromolecules, Applied Microbiology and Biotechnology, Process Biochemistry, Scientific Reports, Enzyme and Microbial Technology, Molecular Catalysis, Materials Chemistry and Physics, Journal of Nanoparticle Research, Applied Biochemistry and Biotechnology, European Food Research and Technology, BMC Pharmacology and Toxicology, Biocatalysis and Biotransformation, Biocatalysis and Agricultural Biotechnology, Spectroscopy Letters, Preparative Biochemistry and Biotechnology, Instrumentation Science and Technology, International Journal of Nanomedicine, Journal of Scientific and Industrial Research, Nanoscience and Nanotechnology Letters, Journal of Nanoscience and Nanotechnology等SCI期刊的審稿人。

研究方向

生物催化與轉化,製藥過程工程。主要包括: (1) 重要藥物中間體的生物法生產新技術開發; (2) 重要生物催化劑的篩選與製備; (3) 製藥過程集成化技術。

學術成果

主持及參與完成國家自然科學基金等多項基金項目,已經發表SCI文章50餘篇,被引近千次,單篇被引最高超200次。以第一作者或通訊作者共發表SCI收錄文章40餘篇,H因子19(2019.5),I10因子33(Google Scholar)。
已發表的代表性論文:
1. Fei-Long Li, Qiang Zhou, Wei Wei, Jian Gao, Ye-Wang Zhang*. Switching the substrate specificity from NAD to NADP by a single mutation of NADH oxidase from Lactobacillus rhamnosus. International Journal of Biological Macromolecules. 2019
2. Fei-Long Li, Qing-Lan Tao, Cai-Yun Liu, Jian Gao, Ye-Wang Zhang*. Role of introduced surface cysteine of NADH oxidase from Lactobacillus rhamnosus. International Journal of Biological Macromolecules. 2019
3. Yi-Hao Zhu, Cai-Yun Liu, Sha Cai, Li-Bin Guo, In-Won Kim, Vipin C Kalia*, Jung-Kul Lee*, Ye-Wang Zhang*. Cloning, expression and characterization of a highly active alcohol dehydrogenase for efficient production of (S)-ethyl-4-chloride-3-hydroxybutyrate. Indian Journal of Microbiology, 2019
4. Fei-Long Li, Meng-Yao Zhuang, Jia-Jia Shen, Xiao-Man Fan, Hyunsoo Choi, Jung-Kul Lee*,Ye-Wang Zhang*. Specific immobilization of recombinant E. coli on mannose functionalized magnetic nanoparticles. Catalysts, 2019
5. Hui Gao, Dakshinamurthy Sivakumar, Tae-Su Kim, Sanjay K. S. Patel, Vipin C Kalia, In-Won Kim*, Ye-Wang Zhang*, Jung-Kul Lee*. NADH oxidase from Lactobacillus reuteri: a versatile enzyme for oxidized cofactor regeneration. International Journal of Biological Macromolecules. 2019
6. Meng-Qiu Xu, Shuang-Shuang Wang, Li-Na Li, Jian Gao*, Ye-Wang Zhang*. Combined cross-linked enzyme aggregates as biocatalysts. Catalysts. 2018
7. Jian Gao, Chun-Liu Lu, Yue Wang, Shuang-Shuang Wang, Jia-Jia Shen, Jiu-Xun Zhang, Ye-Wang Zhang*. Rapid immobilization of cellulase onto graphene oxide with a hydrophobic spacer. Catalysts. 2018
8. Meng-Yao Zhuang, Xiao-Ping Jiang, Xiao-Min Ling, Meng-Qiu Xu, Yi-Hao Zhu, Ye-Wang Zhang*. Immobilization of NADH oxidase and glycerol dehydrogenase for enzymatic synthesis of 1,3-dihydroxyacetone with in situ cofactor regeneration. Journal of Chemical Technology and Biotechnology. 2018
9. Fei-Long Li, Ying Shi, Jiu-Xun Zhang, Jian Gao, Ye-Wang Zhang*. Cloning, expression, characterization and homology modeling of a novel H2O-forming NADH oxidase from Streptococcus mutans ATCC. International Journal of Biological Macromolecules. 2018
10. Jian Gao, Ai-Rong Wang, Xiao-Ping Jiang, Jiu-Xun Zhang, Ye-Wang Zhang*. Immobilization of glycerol dehydrogenase onto epoxy-nanoparticles. Journal of Nanoscience and Nanotechnology. 2018
11. Meng-Yao Zhuang, Cong Wang, Meng-Qiu Xu, Xiao-Min Ling, Jia-Jia Shen, Ye-Wang Zhang*. Using concanavalinA as a spacer for immobilization of E. coli onto magnetic nanoparticles. International Journal of Biological Macromolecules. 2017
12. Guo-Hua Xia, Wei Liu, Xiao-Ping Jiang, Xiang-Yu Wang, Ye-Wang Zhang*, Jianyong Guo. Modification of Fe3O4@SiO2 magnetic nanoparticles for immobilization of lipase. Journal of Nanoscience and Nanotechnology. 2017
13. Meng-Yao Zhuang, Qian-Liu Zhou, Xiang-Yu Wang, Jun-Xi Zhang, Lan Xue, Ru Wang, Jiu-Xun Zhang, Ye-Wang Zhang*. Immobilization of lipase onto dopamine functionalized magnetic nanoparticles. Nanoscience and Nanotechnology Letters, 2016
14. Xiao-Ping Jiang, Ting-Ting Lu, Cai-Hong Liu, Xiao-Ming Ling, Meng-Yao Zhuang, Jiu-Xun Zhang, Ye-Wang Zhang*. Immobilization of alcohol dehydrogenase onto epoxy-functionalized Fe3O4@SiO2 nanoparticles for synthesis of (R)-mandelic acid. International Journal of Biological Macromolecules. 2016
15. Cai-Hong Liu, Xiao-Qian Li, Xiao-Ping Jiang, Meng-Yao Zhuang, Xiao-Min Ling, Jiu-Xun Zhang, Chun-Hai Bao, Ye-Wang Zhang*. Preparation of functionalized graphene oxide nanocomposites for covalent immobilization of NADH oxidase. Nanoscience and Nanotechnology Letters. 2016
16. Xiao-Min Ling, Xiang-Yu Wang, Ping Ma, Yi Yang, Jie-Mei Qin, Xue-Jun Zhang, Ye-Wang Zhang*. Covalent immobilization of penicillin G acylase onto Fe3O4@Chitosan magnetic particles. Journal of Microbiology and Biotechnology, 2016
17. Qing-Lan Tao, Yue Li, Ying Shi, Rui-Jiang Liu, Ye-Wang Zhang*, Jianyong Guo. Application of molecular imprinted magnetic Fe3O4@SiO2 nanoparticles for selective immobilization of cellulase. Journal of Nanoscience and Nanotechnology. 2016
18. Ying Shi, Wei Liu, Qing-Lan Tao, Xiao-Ping Jiang, Cai-Hong Liu, Sha Zeng, Ye-Wang Zhang*. Immobilization of lipase by adsorption onto magnetic nanoparticles in organic solvents. Journal of Nanoscience and Nanotechnology. 2016
19. Xiaoyun Zhang*, Ye-Wang Zhang*, Hongyin Zhang, Qiya Yang, Haiying Wang, Guochao Zhang. Preparation, characterization and antibacterial activity of octenyl succinic anhydride modified inulin. International Journal of Biological Macromolecules. 2015
20. Xiang-Yu Wang, Xiao-Ping Jiang, Yue Li, Sha Zeng, Ye-Wang Zhang*. Preparation Fe3O4@Chitosan magnetic particles for covalent immobilization of lipase from Thermomyces lanuginosus. International Journal of Biological Macromolecules. 2015
21. Yue Li, Xiang-Yu Wang, Xiao-Ping Jiang, Jing-Jing Ye, Ye-Wang Zhang*, Xiao-Yun Zhang. Fabrication of graphene oxide decorated with Fe3O4@SiO2 for immobilization of cellulase. Journal of Nanoparticle Research, 2015
22. Yue Li, Xiang-Yu Wang, Rui-Zhuo Zhang, Xiao-Yun Zhang, Xi-Ming Xu, Ye-Wang Zhang*. Molecular imprinting and immobilization of cellulase onto magnetic Fe3O4@SiO2 nanoparticles. Journal of Nanoscience and Nanotechnology. 2014
23. Wei Liu, Fang Zhou, Xiao-Yun Zhang, Yue Li, Xiang-Yu Wang, Xi-Ming Xu, Ye-Wang Zhang*. Preparation of magnetic Fe3O4@SiO2 nanoparticles for immobilization of lipase. Journal of Nanoscience and Nanotechnology. 2014
24. Jianfeng Wang, Wei Liu, Baoquan Liu, Shengdi Fan, Ye-Wang Zhang*. Analyzing increased fluorescence of single quantum dots on dehydrated agarose by single-molecular imaging. Spectroscopy Letters. 2013
25. Ye-Wang Zhang, Manish Kumar Tiwarri, Hui Gao, Marimuthu Jeya, Jung-kul Lee*. Cloning and characterization of a thermostable H2O-forming NADH oxidase from Lactobacillus rhamnosus. Enzyme and Microbial Technology. 2012
26. Ye-Wang Zhang, Manish Kumar Tiwarri, Marimuthu Jeya, Jung-kul Lee*. Covalent immobilization of recombinant Rhizobium etli CFN42 xylitol dehydrogenase onto modified silica nanoparticles. Applied Microbiology and Biotechnology. 2011
27. Ye-Wang Zhang, Marimuthu Jeya, Jung-Kul Lee*. Enhanced activity and stability of L-arabinose isomerase by immobilization on aminopropyl glass. Applied Microbiology and Biotechnology. 2011
28. Ye-Wang Zhang*, Rui-Jiang Liu, Xi-Ming Xu*. One-pot, two-step enzymatic synthesis of amoxicillin by complexing with Zn. Applied Microbiology and Biotechnology, 2010
29. Ye-Wang Zhang, Marimuthu Jeya, Jung-Kul Lee*. L-Ribulose production by an Escherichia coli harboring L-arabinose isomerase from Bacillus licheniformis. Applied Microbiology and Biotechnology, 2010
30. Ye-Wang Zhang, Ponnandy Prabhu, Jung-Kul Lee*. Alginate immobilization of recombinant Escherichia coli whole cells harboring L-arabinose isomerase for L-ribulose production. Bioprocess and Biosystems Engineering, 2010

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