張楠楠，女，博士，現為安徽大學生命科學學院副教授。
基本介紹
- 中文名：張楠楠
- 畢業院校：中國科學技術大學
- 學位/學歷：博士
- 專業方向：生物化學與分子生物學
人物經歷,研究方向,科研項目,發表文章,獲獎記錄,
人物經歷
研究方向
科研項目
- 主持國家自然科學青年基金：嗜肺軍團菌RpoS調控II型分泌系統效應蛋白磷脂酶A分子機理的研究（31400641）
- 主持高校自然科學研究重點項目：有機溶劑耐受性氨肽酶LapB的底物特異性及理性分子改造研究 （KJ2018A0004）
發表文章
- Gong X, Zhao X, Zhang W, Wang J, Chen X, Hameed MF, Zhang N*, Ge H*. Structural characterization of the hypothetical protein Lpg2622, a new member of the C1 family peptidases from Legionella pneumophila. FEBS Lett. 2018. 592:2798-2810.（*共通訊作者）
- Zhang N, Chen X, Gong X, Li T, Xie Z, Hameed MF, Wang M, Ge H. High-Resolution Crystal Structure of RpoS Fragment including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila. Crystals. 2018. 8.
- Zhang N, Yin S, Zhang W, Gong X, Zhang N, Fang K, Ge H*. Crystal Structure and Biochemical Characterization of an Aminopeptidase LapB from Legionella pneumophila. J Agric Food Chem. 2017, 65 (34), pp 7569–7578.
- Zhang N, Yin S, Liu S, Sun A, Zhou M, Gong X, Ge H*. Crystal structure of lpg1832, a VirK family protein from Legionella pneumophila reveals a novel fold for bacterial VirK proteins. FEBS LETT. 2017 Aug 3. doi: 10.1002/1873-3468.12773.
- Wang W, Hynninen V, Qiu L, Zhang A, Lemma T, Zhang N, Ge H*, Toppari J*, Hytonen V, Wang J*. Synergistic enhancement via plasmonic nanoplate-bacteria-nanorod supercrystals for highly efficient SERS sensing of food-borne bacteria. Sensors and Actuators B: Chemical. 2017, 239:515-525
- Qiu L, Wang W, Zhang A, Zhang N, Lemma T, Ge H*, Toppari J*, Hytonen V, Wang J*. Core-shell nanorod columnar array combined with gold nanoplate-nanosphere assemblies enable powerful in-situ SERS detection of bacteria. ACS Appl. Mater. Interfaces. 2016, 8(37):24394-24403.
- Zhang N, Gong X, Lu M, Chen X, Qin X, Ge H*. Crystal structures of Apo and GMP bound hypoxanthine-guanine phospho-ribosyltransferase from Legionella pneumophila and the implications in gouty arthritis. J Struct Biol.2016,194(3):311-6.
- Qiu L, Wang W, Zhang N, Jia H, Wang J, Ge H. A versatile Anisometric metallic supercrystal with controllable orientation on a chip as stable and reliable label-free biosensor. Chem Asian J. 2016, 11(2):256-264.
- Zhou D, Pan Y, Chen X, Zhang N* , Ge H* . Crystallization and preliminary crystallographic analysis of the major acid phosphatase from Legionella pneumophila. Acta Crystallogr F Struct Biol Commun 2015;71(Pt 6):779-783.（*共通訊作者）
- Chen X, Hu Y, Yang B, Gong X, Zhang N, Niu L, Wu Y, Ge H*. Structure of lpg0406, a carboxymuconolactone decarboxylase family protein possibly involved in antioxidative response from Legionella pneumophila. Protein Sci. 2015, 24(12:2070-2075.
- Jia H, Wang W, Qiu L, Zhang N, Ge H, Wang J. Fabricating a Long-Range Ordered 3D Bimetallic Nanoassembly with Edge-On Substrate for Highly Sensitive SERS Sensing of Escherichia coli Bacteria. Plasmonics. 2015, 10(6):1889-1894.
- Gong X, Chen X, Yu D, Zhang N, Zhu Z, Niu L, Mao Y, Ge H. Crystal structure of Legionella pneumophila dephospho-CoA kinase reveals a non-canonical conformation of P-loop. J Struct Biol. 2014, 188(3):233-239.
- Zhang M, Xu H, Wang Y, Shi Z and Zhang N*. Structure of succinyl-CoA: 3-ketoacid CoA transferase from Drosophila melanogaster. Acta Cryst. F 2013, F69, 1089-1093（通訊作者）
- He Y#, Zhang N#, He Y, Zhang NN, Li WF, Jia N, Chen BY, Zhou K, Zhang J, Chen Y, Zhou CZ. N-Terminal domain of Bombyx mori fibroin mediates the assembly of silk in response to pH decrease. J Mol Biol. 2012, 418: 197-207.（#共第一作者）
- Chen BY, Ma XX, Guo PC, Tan X, Li WF, Yang JP, Zhang NN, Chen Y, Xia Q, Zhou CZ. Structure-guided activity restoration of the silkworm glutathione transferase Omega GSTO3-3. J Mol Biol, 2011, 412: 204-211.
- Zhang NN, He YX, Li WF, Teng YB, Yu J, Chen Y, Zhou CZ. Crystal structures of holo and Cu-deficient Cu/Zn-SOD from the silkworm Bombyx mori and the implications in amyotrophic lateral sclerosis. Proteins, 2010, 78: 1999-2004.
- Yu J, Zhang NN, Yin PD, Cui PX, Zhou CZ. Glutathionylation-triggered conformational changes of glutaredoxin Grx1 from the yeast Saccharomyces cerevisiae. Proteins, 2008, 72: 1077-1083.
