張新歌

張新歌 女，籍貫河南省 。學歷 博士 ，南開大學副教授 ，二級學科 ，高分子化學與物理，所在單位 高分子化學研究所， 畢業院校南開大學。

基本介紹

• 中文名：張新歌
• 國籍：中國
• 職業：副教授
• 畢業院校：天津師範大學

人物經歷

2003年畢業於天津師範大學，獲得碩士學位。

2006年畢業於南開大學，獲得博士學位。

同年畢業留高分子所工作至今。

目前還擔任Biomacromolecules, Molecular Pharmaceutics, Nanomedicine-UK, International Journal of Pharmaceutics, Carbohydrate Polymers, Carbohydrate Research, Journal of Biomaterials Science, polymer Edition, Drug News and Perspectives, European Journal of Chemistry, Asian Journal of Pharmaceutics, Current Drug Delivery等國際期刊審稿人。

研究方向

生物醫用高分子研究、藥物傳遞、細胞支架的設計與合成、智慧型高分子材料研究；

具有特殊鏈構造的非線型生物高分子設計與合成；
基於多肽、多糖和生物可降解性高分子的生物醫用材料；
光、磁、熱、糖和 pH 回響性環境敏感智慧型材料；
藥物緩釋、控釋及生物活性物質傳輸的載體材料；
環境回響性無機/有機雜化納米材料；
抗菌高分子材料；

主要貢獻

研究成果發表在Biomaterials，Journal of Controlled Release, Biomacromolecules，Acta Biomaterialia，Polymer，European Journal of Pharmaceutics and Biopharmaceutics，New Journal of Chemistry，Carbohydrate Polymers, Journal of Colloid and Interface Science等期刊上，共發表SCI論文30餘篇。

科研項目

1.天津市自然科學基金：生物大分子藥物黏膜智慧型化給藥的納米載體材料研究（已結題）；

2.國家自然科學基金： 新型含生物黏附性和酶抑制活性兩親性高分子藥物載體材料的研究（2009.1-2011.12）；
3.教育部博士點基金：新型鼻腔給藥載體材料的研究（2009.1-2011.12）；

4.國家自然科學基金：用於銅綠假單胞菌識別拓撲生物高分子的構建及其與蛋白質相互作用研究（2012.1-2015.12）；

研究成果

1.Xuejiao Zhang, Xinge Zhang*, Zhongming Wu, Xiujun Gao, Cui Cheng, Chaoxing Li, Zhen Wang. A novel hydrotropic β-cyclodextrin grafted hyperbranched polyglycerol copolymer for hydrophobic drug delivery. Acta Biomaterialia 2011, 7:585-592.

2. Xuejiao Zhang, Xinge Zhang*, Zhongming Wu, Xiujun Gao, Cui Cheng, Chaoxing Li*,Zhen Wang. β-Cyclodextrin grafted hyperbranched polyglycerols as carriers for nasal insulin delivery. Carbohydrate Polymers 2011, 84:1419-1425.

3.Shujun Shu, Xinge Zhang*, Zhongming Wu, Zhen Wang, Chaoxing Li*. Gradient cross-linked biodegradable polyelectrolyte nanocapsules for intracellular protein drug delivery. Biomaterials 2010, 31(23):6039-6049.

4.Teng Dayong, Wu Zhongming, Zhang Xinge*, Zhang shaomin, Zheng Chao, Wang Zhen, Li Chaoxing*. Synthesis and characterization of in situ cross-linked hydrogel based on self-assembly of thiol-modified chitosan with PEG diacrylate using Michael type addition. Polymer 2010, 51:639-646.

5.Shujun Shu, Chunyang Sun, Xinge Zhang*, Zhongming Wu, Zhen Wang, Chaoxing Li*. Hollow and degradable polyelectrolyte nanocapsules for protein drug delivery. Acta Biomaterialia 2010, 6:210-217.

6.Xiujun Gao, Xinge Zhang*, Zhongming Wu, Xuejiao Zhang, Zhen Wang, Chaoxing Li*. Synthesis and physicochemical characterization of a novel amphiphilic polylactic acid-hyperbranched polyglycerol conjugate for protein drug delivery. Journal of Controlled Release 2009, 140:141-147.

7.Shujun Shu, Xin Wang, Xinge Zhang*, Zhen Wang, Chaoxing Li*. Disulfide cross-linked biodegradable polyelectrolyte nanoparticles as oral protein drugs delivery. New Journal of Chemistry 2009, 33:1882-1887.

8.Xingju Jin, Xinge Zhang*, Zhongmin Wu, Dayong Teng, Xuejiao Zhang, Yanxia Wang, Zhen Wang, Chaoxing Li*. Amphiphilic random glycopolymer based on phenylboronic acid: Synthesis, characterization, and potential as glucose-sensitive matrix. Biomacromolecules 2009, 10:1337-1345.

9.Xinge Zhang*,Zhongming Wu, Xiujun Gao, Shujun Shu, Huijie Zhang, Zhen Wang, Chaoxing Li. Chitosan bearing pendant cyclodextrin as a carrier for controlled protein release. Carbohydrate Polymers 2009, 77:394-401.

10.Dayong Teng, Jingli Hou, Xinge Zhang*, Xin Wang, Zhen Wang, Chaoxing Li*. Glucosamine-carrying temperature- and pH-sensitive microgels: preparation, characterization and in vitro drug release studies. Journal of Colloid and Interface Science 2008, 322: 333-341.

11.Xinge Zhang, Huijie Zhang, Zhongming Wu, Zhen Wang, Haimei Niu, Chaoxing Li. Nasal absorption enhancement of insulin by using PEG-g-chitosan nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics 2008, 68(3):526-534.