人物經歷
2019/01-至今, 中國海洋大學,教授
2016/02-2018/12,香港科技大學,博士後
2012/02-2016/01,香港科技大學,博士
2011/11-2012/01,香港科技大學,研究助理
2011/07-2011/10,西北農林科技大學,研究助理
2008/09-2011/06,中國科學院,碩士
2004/09-2008/06,山東大學,本科
研究方向
研究關注的科學命題是全球氣候變化與海洋生物被膜微生物圈(biofilm microbial sphere)的相互作用。
主持的科研項目
(1)中國海洋大學優青培育計畫,2020-2022,課題負責人
(2)中國海洋大學英才工程第一層次,2019-2020,課題負責人
(3)國家重點研發計畫,2018-2021,子課題負責人
(4)國家重點研發計畫,2018-2021,子課題負責人
主要成就
代表性論文:
(1)Zhang W, Ding W, Li YX, Tam C, Bougouffa S, Wang R, Pei B, Chiang H, Leung P, Lu Y, Sun J, Fu H, Bajic VB, Liu H, Webster NS, Qian PY. Marine biofilms constitute a bank of hidden microbial diversity and functional potential. Nature Communications, 2019, 10:517. (IF=12.1)
(2)Lin J#, Zhang W#, Cheng J, Yang X, Zhu K, Wang Y, Wei G, Qian PY, Luo ZQ, Shen XH. A Pseudomonas T6SS effector recruits PQS-containing outer membrane vesicles for iron acquisition. Nature Communications,2017, 8:14888. (IF=12.1)
(3) Zhang W, Sun J, Cao H, Tian R, Cai L, Ding W, Qian PY. Post-translational modifications are enriched within protein functional groups important to bacterial adaptation within a deep-sea hydrothermal vent environment. Microbiome, 2016, 4:49. (IF=10.5)
(4)Sun J, Chen C, Miyamoto N, Li R, Sigwart JD, Xu T, Sun Y, Wong WC, Ip JCH, Zhang W, Lan Y, Bissessur D, Watsuji TO, Watanabe HK, Takaki Y, Ikeo K, Fujii N, Yoshitake K, Qiu JW, Takai K, Qian PY. The scaly-foot snail genome and implications for the origins of biomineralised armour. Nature Communications, 2020, DOI: 10.1038/s41467-020-15522-3 (IF=12.1)
(5) Li ZR, Li J, Cai W, Lai JYH, McKinnie SMK, Zhang W, Moore BS, Wenjun Zhang, Qian PY. Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage. Nature Chemistry, 2019, 11:880-889. (IF=23.2)
(6) Li YX, Zhong Z, Hou P, Zhang W, Qian PY. Resistance to nonribosomal peptide antibiotics mediated by D-stereospecific peptidases. Nature Chemical Biology, 2018, 14:381-387. (IF=12.2)
(7) Li YX, Zhong Z, Zhang W, Qian PY. Discovery of cationic nonribosomal peptides as Gram-negative antibiotics through global genome mining. Nature Communications, 2018, 9:1-9. (IF=12.1)
(8) Sun J, Zhang Y, Xu T, Zhang Y, Mu H, Zhang Y, Lan Y, Fields CJ, Hui JHL, Zhang W, Li R, Nong W, Cheng FKM, Qiu JW, Qian PY. Mussel genomes provide insights into adaptation to deep-sea chemosynthetic environments. Nature Ecology & Evolution, 2017, 1:0121. (IF=11.0)
(9) Li ZR, Li J, Gu JP, Lai JY, Duggan BM, Zhang W, Li ZL, Li YX, Tong RB, Xu Y, Lin DH, Moore B, Qian PY. Divergent biosynthesis yields a cytotoxic aminomalonate-containing precolibactin. Nature Chemical Biology, 2016, 12:773-775. (IF=12.2)