常興,中國科學院上海生命科學研究所健康所研究組長、博士生導師。
簡歷: |
1997-2001:北京大學生物生命科學學院,生物學士 2001-2006:美國俄亥俄州立大學,病理系,免疫學博士 2007-2012:美國耶魯大學免疫學系博士後(PostdoctoralResearchAssociate) 2012- 中國科學院上海生命科學院/上海交通大學醫學院健康科學研究所組長 |
研究方向: |
研究重點為:(1)T細胞亞群分化的信號轉導機制;(2)RNA及RBP調控T細胞功能的機理;(3)免疫耐受的細胞與分子機制 |
職稱: |
研究員 |
職務: |
研究組長、博士生導師 |
獲獎及榮譽: |
2008:美國Gershon/TrudeauImmunology博士後獎 2011:中組部“青年千人計畫” |
代表論著: |
Chang X, Liu F, Wang X, Lin A, Zhao H, and Su B 2011. The Kinases MEKK2 and MEKK3 Regulate Transforming Growth Factor-β-Mediated Helper T Cell Differentiation.Immunity. 34(2): 201-212. Enzler T,Chang X, Facchinetti V, Melino G, Karin M, Su B, Gallagher E. 2009. MEKK1 Binds HECT E3 Ligase Itch by Its Amino-Terminal RING Motif to Regulate Th2 Cytokine Gene Expression.J Immunol. 183(6): 3831-3838. Wang XF,Chang X, Facchinetti V, Zhuang Y,and Su B. 2009. MEK Kinase 3 is essential for lymphopenia-Induced T cell Proliferation and Survival.J Immunol. 182(6):3597-608. Chang X, Zheng P, and Liu Y 2009. Selective Elimination of Autoreactive T cells in vivo by the Regulatory T Cells.Clin Immunol. 130(1):61-73. Chang X, Zheng P, and Liu Y 2008. Homeostatic proliferation in the mice with germline FoxP3 mutation and its contribution to fatal autoimmunity.J Immunol. 181(4):2399-406. Chen GY, Chen C, Wang L,Chang X, Zheng P, Liu Y. 2008. Cutting edge: Broad expression of the FoxP3 locus in epithelial cells: a caution against early interpretation of fatal inflammatory diseases following in vivo depletion of FoxP3-expressing cells.J Immunol. 180(8):5163-6. |