孟賡，男，博士，中國農業大學動物醫學院副教授、碩士生導師。
基本介紹
- 中文名：孟賡
- 出生日期：1982年6月
- 學位/學歷：博士
- 任職院校：中國農業大學
研究方向,發表論文,
研究方向
科研領域及專長
病毒組裝機制研究，基於結構的亞單位納米顆粒疫苗設計，病毒免疫學研究。
分子病毒學，結構病毒學，結構生物學（X射線衍射晶體學和高解析度冷凍電鏡），蛋白質生物化學，分子生物學，免疫學。
工程領域及專長
診斷抗原和抗體製備，快速診斷試劑研發，疫苗開發。
發表論文
1：Sialic acid-dependent cell entry of human enterovirus D68.Liu Y, Sheng J, Baggen J, Meng G, Xiao C, Thibaut HJ, van Kuppeveld FJ, Rossmann MG.Nat Commun. 2015 Nov 13;
2: Kanekiyo M, Bu W, Joyce MG, Meng G, Whittle JR, Baxa U, Yamamoto T, Narpala S, Todd JP, Rao SS, McDermott AB, Koup RA, Rossmann MG, Mascola JR, Graham BS, Cohen JI, Nabel GJ.Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site.Cell. 2015 Aug 27
3: Liu Y, Sheng J, Fokine A, Meng G, Shin WH, Long F, Kuhn RJ, Kihara D, Rossmann MG.Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.Science. 2015 Jan 2;
4: Xiao W, Meng G（co-first）, Zhao Y, Yuan H, Li T, Peng Y, Zhao Y, Luo M, Zhao W, Li Z, Zheng X.
Human secreted stabilin-1-interacting chitinase-like protein aggravates the inflammation associated with rheumatoid arthritis and is a potential macrophage inflammatory regulator in rodents.Arthritis Rheumatol. 2014 May
5: Meng G, An X, Ye S, Liu Y, Zhu W, Zhang R, Zheng X.The crystal structure of LidA, a translocated substrate of the Legionella pneumophila type IV secretion system.Protein Cell. 2013 Dec;4
6: Meng G, Zhang X, Plevka P, Yu Q, Tijssen P, Rossmann MG.The structure and host entry of an invertebrate parvovirus.J Virol. 2013 Dec
7: Wang Z, Li L, Pennington JG, Sheng J, Yap ML, Plevka P, Meng G, Sun L, Jiang W, Rossmann MG. Obstruction of dengue virus maturation by Fab fragments of the 2H2 antibody.J Virol. 2013 Aug
8: Liu Y, Meng G, Luo M, Zheng X.Crystallization and X-ray crystallographic analysis of the cap-binding domain of influenza A virus H1N1 polymerase subunit PB2.Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1
9: Liu Y, Qin K, Meng G, Zhang J, Zhou J, Zhao G, Luo M, Zheng X.Structural and functional characterization of K339T substitution identified in the PB2 subunit cap-binding pocket of influenza A virus.J Biol Chem. 2013 Apr 19
10: Battisti AJ, Meng G（co-first）, Winkler DC, McGinnes LW, Plevka P, Steven AC, Morrison TG, Rossmann MG.Structure and assembly of a paramyxovirus matrix protein.Proc Natl Acad Sci U S A. 2012 Aug 28
11: Bai X, Meng G（co-first）, Luo M, Zheng X. Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules.J Biol Chem. 2012 Jun 22
12: Bai X, Meng G, Zheng X. Cloning, purification, crystallization and preliminary X-ray diffraction analysis of mouse PACSIN 3 protein.Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1
13: Zhu W, Meng G, Liu Y, Zhang F, Zheng X. Protein expression, crystallization and preliminary X-ray crystallographic studies of LidA from Legionella pneumophila.Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1
14: Meng G, Zhao Y, Bai X, Liu Y, Green TJ, Luo M, Zheng X.Structure of human stabilin-1 interacting chitinase-like protein (SI-CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivity.J Biol Chem. 2010 Dec 17
15: Li G, Qu L, Meng G, Bai X, Dai K, Zheng X.Crystallization and preliminary X-ray crystallographic studies of human FAIM protein.Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Aug 1
16: Bai X, Meng G, Li G, Luo M, Zheng X.Crystallization and preliminary X-ray crystallographic analysis of human PACSIN 1 protein.Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jan 1
17: Li G, Tang Z, Meng G, Dai K, Zhao J, Zheng X. Crystallization and preliminaryX-ray crystallographic studies of O-methyltransferase from Anabaena PCC 7120.Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Oct 1
18: Meng G, Bai X, Green TJ, Luo M, Zheng X. Crystallization and preliminaryX-ray crystallographic studies on SI-CLP, a novel human Glyco_18 domain-containing protein. Protein Pept Lett. 2009
19: Dai X, Li Y, Meng G, Yao S, Zhao Y, Yu Q, Zhang J, Luo M, Zheng X.NADPH is an allosteric regulator of HSCARG.J Mol Biol. 2009 Apr 17
20: Meng G, Zhai R, Liu B, Zheng X. Identification of a novel nuclear-localized adenylate kinase from Drosophila melanogaster.Biochemistry. 2008 Jan
21: Zhai R, Meng G（co-first）, Zhao Y, Liu B, Zhang G, Zheng X.A novel nuclear-localized protein with special adenylate kinase properties from Caenorhabditis elegans.FEBS Lett. 2006 Jul 10
