姚康，男，中國科學院亞熱帶農業生態研究所研究員，博士生導師
基本介紹
- 中文名：姚康
- 畢業院校：中國科學院亞熱帶農業生態研究所
- 職業：教師
- 性別：男
- 單位：中國科學院亞熱帶農業生態研究所
人物經歷,研究概況,主持項目,論文目錄,
人物經歷
2002年7月畢業於華中農業大學畜牧獸醫專業，獲農學學士學位；
2005年7月畢業於華中農業大學動物科技學院，獲得豬遺傳育種與營養調控專業碩士學位；
2009年3月畢業於中國科學院亞熱帶農業生態研究所，獲得動物營養與生態專業博士學位。
2009年5月至2014年3月在Department of Animal Science, Texas A&M University進行科研工作。
研究概況
從事單胃動物(豬)的營養研究以來，主要以進一步提高營養成分利用效率，促進蛋白質合成和沉積為研究方向，並圍繞胺基酸及胺基酸代謝中間產物對蛋白質合成及合成信號通路即mTOR信號通路中各蛋白質翻譯起始因子的調節作用開展了各項工作,先後參加國家自然科學基金項目3項、國家973課題2項，先後主持國家自然科學基金青年基金項目、湖南省自然科學基金重點項目各1項，973項目專項負責人，發表學術論文20餘篇，SCI 收錄16篇，文章收錄發表後截止2014年3月他引次數達334次，參與編寫專著1部，作為主要完成人獲湖南省自然科學一等獎1項。
主持項目
2010.1-2012.12 國家自然科學基金青年基金項目“a-酮戊二酸對谷氨醯胺在腸道第一代謝率的影響作用及機理的研究”（30901041），為項目負責人。
2012.1-2014.12 湖南省自然科學基金重點項目“嘔吐毒素解毒酶構建及其對飼料營養物質吸收的影響機制”(12JJ2020)，為項目負責人。
2013.1-2017. 12國家973項目“氮營養素消化代謝網路的整合機制與營養調控”，子課題負責人。
論文目錄
1. Kang Yao, Yulong Yin, Guoyao Wu, Dun Deng, Zhiqiang Liu, Tijun Li, Ruilin Huang, Wuyin Chu, Bie Tan and Wence Wang. Dietary Arginine Supplementation Increases mTOR Signaling Activity in Skeletal Muscle of Neonatal Pigs. Journal of Nutrition. 2008：867-872
2. Kang Yao, Dun Deng, Wuying Chu，Tiejun Li , Ruiling Huang , Yulong Yin Zhiqiang Liu , Jianshe Zhang , and Guoyao Wu. Impaired translation initiation activation and reduced protein synthesis in weaned piglets fed a low-protein diet. Journal of Nutritional Biochemistry. (Co-author made equal contributions to the study) 2009 20 (7)：544-552
3. Kang Yao, Yu-Long Yin, Guoyao Wu, Dun Deng, Zhiqiang Liu, Tijun Li, Ruilin Huang, Wuyin Chu, Bie Tan and Wence Wang. Dietary L-arginine supplementation enhances intestinal development and expression of vascular endothelial growth factor in weanling piglets. British journal of nutrition. 105(5):703-9
4. Kang Yao , Yulong Yin Zhiqiang Liu , Jianshe Zhang , and Guoyao Wu. Tryptophan metabolism and its implications for nutrition. Frontiers in Bioscience. S3, 286-297
5. Kang Yao, Yulong Yin, Xilong Li, Pengbin Xi, Junjun Wang, Jian Lei, Yongqing Hou, Guoyao Wu. Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells. Amino Acids. DOI 10.1007/s00726-011-1060-6
6. Kang Yao，Li Wu, Wence Wang, Ting Zhou, Jie Yin, Tiejun Li, Lin Yang, Liuqin He, Xiaojian Yang, Hongfu Zhang, Qi Wang, Ruilin Huang, Yulong Yin. Effects of Dietary Arginine and Glutamine on Alleviating the Impairment Induced by Deoxynivalenol Stress and Immune Relevant Cytokines in Growing Pigs. (Co-author made equal contributions to the study) PLoS ONE. 2013 8(7): e69502. doi:10.1371/journal.pone.0069502
7. Kang Yao, Chenxing Fu, Sudath Dahanayaka, Jian Lei, Wei Lu, Guoyao Wu and YulongYin. Dietary alpha-ketoglutarate supplementation may increases muscle gain through mTOR signaling pathway in diet-induced obese rat. JFAE 2013 11 (3&4) - 2013
8. Zhengfeng Fang, Kang Yao, Xiaoling Zhang, Shengjun Zhao, Zhihong Sun, Gang Tian, Bing Yu, Yan Lin, Biquan Zhu, Gang Jia, Keying Zhang, Daiwen Chen, De Wu. Nutrition and health relevant regulation of intestinal sulfur amino acid metabolism. Amino Acids. (2010) 39:633–640.
9. Yulong Yin, Kang Yao, Zhaojin Liu, Min Gong, Zheng Ruan, Dun Deng, Bie Tan, Zhiqiang Liu, Guoyao Wu. Supplementing L-leucine to a low-protein diet increases tissue protein synthesis in weanling pigs. Amino Acids. (2010) 39:1477–1486
10. Yongqing Hou, Kang Yao, Lei Wang1, Binying Ding, Dabo Fu, Yulan Liu, Huiling Zhu, Jian Liu, Yongtang Li, Ping Kang, Yulong Yin and Guoyao Wu. Effects of α-ketoglutarate on energy status in the intestinal mucosa of weaned piglets chronically challenged with lipopolysaccharide. Brtish Journal Nutrition. (2011), 106, 357–363
11. Pengbin Xi, Zongyong Jiang, Zhaolai Dai, Xilong Li, Kang Yao, Chuntian Zheng,Yingcai Lin, Junjun Wang, Guoyao Wu. Regulation of protein turnover by L-glutamine in porcine intestinal epithelial cells. Journal of Nutritional Biochemistry. 2012,23(8):1012-7
12.Jian Lei, Dingyuan Feng, Yongliang Zhang, Sudath Dahanayaka, Xilong Li, Kang Yao, Junjun Wang, Zhenlong Wu, Zhaolai Dai, Guoyao Wu. Regulation of leucine catabolism by metabolic fuels in mammary epithelial cells. Amino Acids. (2012) 04/2012; 43(5):2179-89.
13.Jian Lei, Dingyuan Feng, Yongliang Zhang, Sudath Dahanayaka, Xilong Li, Kang Yao, Junjun Wang, Zhenlong Wu, Zhaolai Dai, Guoyao Wu. Hormonal regulation of leucine catabolism in mammary epithelial cells.Amino Acids. (2012) DOI 10.1007/s00726-012-1332-9
14.Carmen D. Tekwe, Jian Lei, Kang Yao, Reza Rezaei, Xilong Li, Sudath Dahanayaka, Raymond J. Carroll, Cynthia J. Meininger, Fuller W. Bazer, Guoyao Wu. Oral administration of interferon tau enhances oxidation of energy substrates and reduces adiposity in Zucker diabetic fatty rats. BioFactors. (2013) DOI 10.1002/biof.1113.
15.Bie Tan, Yulong Yin, Zhiqiang Liu, Wenjie Tang, Haijun Xu,Xiangfeng Kong, Xinguo Li, Kang Yao, Wanting Gu, Stephen B Smith, Guoyao Wu. Dietary L-arginine supplementation differentially regulates expression of lipid-metabolic genes in porcine adipose tissue and skeletal muscle. The Journal of nutritional biochemistry (2011); 22(5):441-5.
16.Bie Tan, Xinguo G Li, Xiangfeng Kong, Ruilin Huang, Zheng Ruan, Kang Yao, Zeyuan Deng, Mingyong Xie, Izuru Shinzato, Yulong Yin,Guoyao Wu. Dietary L-arginine supplementation enhances the immune status in early-weaned piglets. Amino Acids 09/2008; 37(2):323-31.
