基本介紹
- 中文名：唐建斌
- 學位/學歷：博士
- 職業：教師
- 專業方向：· 生物醫用材料· 納米探針與分子成像· 納米技術與藥物輸送
- 職務：生物工程研究所副所長、國際交流與合作處副處長（掛職）
- 職稱：教授
- 任職院校：浙江大學
個人經歷,研究方向,主講課程,學術成果,研究項目,發表論文,出版著作,專利成果,榮譽獎項,
個人經歷
1997-2001年，桂林理工大學材料系本科畢業；
2001－2006年，浙江大學沈之荃院士課題組攻讀博士學位，其間2004－2006年，美國懷俄明大學進行聯合培養；
2006－2008年，美國懷俄明大學從事博士後研究工作。
2008年至今，浙江大學化工學院講師、副教授、教授、生物工程研究所副所長。
2012年12月-2013年3月在美國史丹福大學醫學院作訪問副教授；
2019年6月-8月劍橋大學化學工程與生物技術系訪問學者。
研究方向
· 生物醫用材料
· 納米探針與分子成像
· 納米技術與藥物輸送
主講課程
生物納米技術碩/博研究生
生物製藥技術本科生
生物製藥選論碩/博研究生
學術成果
作為項目負責人承擔了國家自然科學基金委優秀青年基金、面上項目3項和青年項目1項，並獲浙江省傑青和“錢江人才計畫”項目資助；作為骨幹參與國家自然科學基金重大項目、納米研究國家重大研究計畫和973項目各1項。至今，已發表SCI收錄論文100多篇，其中大量論文發表在《Journal of the American Chemical Society》、《Advanced Materials》、《Progress in Polymer Science》、《Advanced Functional Materials》、《Chemical Science》、《Journal of Controlled release》、《Macromolecules》和《Chemical Communications》等高影響力的期刊上，論文被SCI他引3000多次，H-index 為30，並獲得發明專利授權10餘項。
研究項目
2. 小肝癌靶向樹枝狀大分子造影劑的合成與成像研究（21774109）；國家自然科學基金委面上項目，2018- 2021（負責人）
3. 化療與免疫治療一體化藥物輸送系統的構建和抗癌研究（LR18E030002）；浙江省傑出青年基金，2018- 2021 （負責人）
3. 載體與緩釋材料（51522304）；國家自然科學基金委優秀青年基金；2016-2018（負責人）
4. 高效核酸納米輸送系統的研究；國家重大研究計畫項目；科技部 （2014CB931900）2014-2018 (研究骨幹)
5. pH回響的磁共振成像納米造影劑的製備與腫瘤成像研究；國家自然科學基金面上項目(21174128)；2012-2015 （負責人）
6. 新型可生物降解樹枝狀大分子磁共振成像造影劑的合成及在腫瘤成像上的套用; 國家自然科學青年基金(20904046); 2010.1-2012.12 (負責人)
7. 基於可生物降解樹枝狀大分子磁共振成像造影劑的製備與性能研究;教育部博士點新教師基金 (20090101120159 ); 2010.1-2012.12 (負責人)
8. 新型高分子抗菌母粒的研發；橫向，杭州聯通管業有限公司；2013.1-2013.12 （負責人）
9. 新型納米抗菌PE/PPR管材的開發; 橫向，杭州聯通管業有限公司 (H20100144 ); 2010.1-2010.12 (負責人)
10. 腫瘤靶向型可生物降解樹枝狀大分子磁共振造影劑的研製; 浙江省錢江人才計畫(2010R10050); 2010.9-2013.9(負責人)
11. 聚離子液體無機納米材料雜化膜及其在CO2氣體分離的套用; 教育部留學回國人員啟動基金 (教外司留[2010]609號); 2010.1-2011.12 (負責人)
12. 利用腫瘤細胞核靶向藥物輸送克服腫瘤抗藥性的研究; 973計畫前期研究專項，科技部; 2009.4-20011.8 (主要參與人)
13. 拓撲高分子的高效合成；國家自然科學基金委，2011.1-2014.12 (主要參與人)
發表論文
1. Zhou, Q.; Shao, S.; Wang, J.; Xu, C.; Xiang, J.; Piao, Y.; Zhou, Z.; Yu, Q.; Tang, J.; Liu, X.; Gan, Z.; Mo, R.; Gu, Z.; Shen, Y., Enzyme-activatable polymer-drug conjugate augments tumour penetration and treatment efficacy. Nature Nanotechnology 2019, 14 (8), 799-.
2. Wang, J.; Hu, S.; Mao, W.; Xiang, J.; Zhou, Z.; Liu, X.; Tang, J.; Shen, Y., Assemblies of Peptide-Cytotoxin Conjugates for Tumor-Homing Chemotherapy. Advanced Functional Materials 2019, 29 (7).
3. Han, Y.; Zhou, X.; Qian, Y.; Hu, H.; Zhou, Z.; Liu, X.; Tang, J.; Shen, Y., Hypoxia-targeting dendritic MRI contrast agent based on internally hydroxy dendrimer for tumor imaging. Biomaterials 2019, 213.
4. Zhou, X.; Liu, Z.; Wang, H.; Liu, X.; Zhou, Z.; Tang, J.; Liu, X.; Zheng, M.; Shen, Y., SAHA (vorinostat) facilitates functional polymer-based gene transfection via upregulation of ROS and synergizes with TRAIL gene delivery for cancer therapy. Journal of Drug Targeting 2019, 27 (3), 306-314.
5. Gu, S.-f.; Wang, L.-y.; Tian, Y.-j.; Zhou, Z.-x.; Tang, J.-b.; Liu, X.-r.; Jiang, H.-p.; Shen, Y.-q., Enhanced water solubility, antioxidant activity, and oral absorption of hesperetin by D--tocopheryl polyethylene glycol 1000 succinate and phosphatidylcholine. Journal of Zhejiang University-Science B 2019, 20 (3), 273-281.
6. Zhu, D.; Yan, H.; Zhou, Z.; Tang, J.; Liu, X.; Hartmann, R.; Parak, W. J.; Feliu, N.; Shen, Y., Detailed investigation on how the protein corona modulates the physicochemical properties and gene delivery of polyethylenimine (PEI) polyplexes. Biomaterials Science 2018, 6 (7), 1800-1817.
7. Zhou, Q.; Wang, Y.; Xiang, J.; Piao, Y.; Zhou, Z.; Tang, J.; Liu, X.; Shen, Y., Stabilized calcium phosphate hybrid nanocomposite using a benzoxaborole-containing polymer for pH-responsive siRNA delivery. Biomaterials Science 2018, 6 (12), 3178-3188.
8. Zhang, Z.; Zhou, Y.; Zhou, Z.; Piao, Y.; Kalva, N.; Liu, X.; Tang, J.; Shen, Y., Synthesis of enzyme-responsive phosphoramidate dendrimers for cancer drug delivery. Polymer Chemistry 2018, 9 (4), 438-449.
9. Yu, W.; Ye, M.; Zhu, J.; Wang, Y.; Liang, C.; Tang, J.; Tao, H.; Shen, Y., Zinc phthalocyanine encapsulated in polymer micelles as a potent photosensitizer for the photodynamic therapy of osteosarcoma. Nanomedicine-Nanotechnology Biology and Medicine 2018, 14 (4), 1099-1110.
10. Yan, H.; Zhu, D.; Zhou, Z.; Liu, X.; Piao, Y.; Zhang, Z.; Liu, X.; Tang, J.; Shen, Y., Facile synthesis of semi-library of low charge density cationic polyesters from poly(alkylene maleate)s for efficient local gene delivery. Biomaterials 2018, 178, 559-569.
11. Xiao, B.; Zhou, X.; Xu, H.; Wu, B.; Hu, D.; Hu, H.; Pu, K.; Zhou, Z.; Liu, X.; Tang, J.; Shen, Y., Integration of Polymerization and Biomineralization as a Strategy to Facilely Synthesize Nanotheranostic Agents. Acs Nano 2018, 12 (12), 12682-12691.
12. Xiang, J.; Wu, B.; Zhou, Z.; Hu, S.; Piao, Y.; Zhou, Q.; Wang, G.; Tang, J.; Liu, X.; Shen, Y., Synthesis and evaluation of a paclitaxel-binding polymeric micelle for efficient breast cancer therapy. Science China-Life Sciences 2018, 61 (4), 436-447.
13. Xiang, J.; Liu, X.; Zhou, Z.; Zhu, D.; Zhou, Q.; Piao, Y.; Jiang, L.; Tang, J.; Liu, X.; Shen, Y., Reactive Oxygen Species (ROS)-Responsive Charge-Switchable Nanocarriers for Gene Therapy of Metastatic Cancer. Acs Applied Materials & Interfaces 2018, 10 (50), 43352-43362.
14. Sun, X.; Wang, G.; Zhang, H.; Hu, S.; Liu, X.; Tang, J.; Shen, Y., The Blood Clearance Kinetics and Pathway of Polymeric Micelles in Cancer Drug Delivery. Acs Nano 2018, 12 (6), 6179-6192.
15. Jiang, H.; Wang, S.; Zhou, X.; Wang, L.; Ye, L.; Zhou, Z.; Tang, J.; Liu, X.; Teng, L.; Shen, Y., New path to treating pancreatic cancer: TRAIL gene delivery targeting the fibroblast-enriched tumor microenvironment. Journal of Controlled Release 2018, 286, 254-263.
16. Hu, D.; Xu, H.; Xiao, B.; Li, D.; Zhou, Z.; Liu, X.; Tang, J.; Shen, Y., Albumin-Stabilized Metal-Organic Nanoparticles for Effective Delivery of Metal Complex Anticancer Drugs. Acs Applied Materials & Interfaces 2018, 10 (41), 34974-34982.
17. Zhu, D.; Yan, H.; Liu, X.; Xiang, J.; Zhou, Z.; Tang, J.; Liu, X.; Shen, Y., Intracellularly Disintegratable Polysulfoniums for Efficient Gene Delivery. Advanced Functional Materials 2017, 27 (16).
18. Zhou, X.; Ye, M.; Han, Y.; Tang, J.; Qian, Y.; Hu, H.; Shen, Y., Enhancing MRI of liver metastases with a zwitterionized biodegradable dendritic contrast agent. Biomaterials Science 2017, 5 (8), 1588-1595.
19. Zhang, S.; Wang, T.; Tang, J.; Liu, X.; Shen, Y., Enhanced antitumor effect of poly(L-glutamic acid)-rose bengal conjugate nanoparticle. Journal of Controlled Release 2017, 259, E122-E123.
20. Ye, M.; Tang, J.; Gao, J.; Liu, X.; Zhou, Z.; Shen, Y., Synergy of photodynamic therapy and chemotherapy with light-triggered drug release. Journal of Controlled Release 2017, 259, E97-E97.
21. Ye, M.; Han, Y.; Tang, J.; Piao, Y.; Liu, X.; Zhou, Z.; Gao, J.; Rao, J.; Shen, Y., A Tumor-Specific Cascade Amplification Drug Release Nanoparticle for Overcoming Multidrug Resistance in Cancers. Advanced Materials 2017, 29 (38).
22. Xiang, J.; Zhou, Q.; Liu, X.; Liu, X.; Tang, J.; Zhou, Z.; Shen, Y., Arginine analogue-modified PAMAM leads to enhanced gene transfection efficiency. Journal of Controlled Release 2017, 259, E57-E57.
23. Xia, M.; Ye, M.; Zhou, X.; Tang, J.; Piao, Y.; Liu, X.; Zhou, Z.; Hu, H.; Shen, Y., A facile synthesis of a theranostic nanoparticle by oxidation of dopamine-DTPA-Gd conjugates. Journal of Materials Chemistry B 2017, 5 (44), 8754-8760.
24. Wang, L.; Zhou, Q.; Liu, X.; Zhou, Z.; Tang, J.; Shen, Y., Enhanced anti-tumor efficacy by co-delivery of GDC-0449 with size-tunable polymeric SN38 nanoparticles in pancreatic cancer. Journal of Controlled Release 2017, 259, E87-E88.
25. Wang, L.; Liu, X.; Zhou, Q.; Sui, M.; Lu, Z.; Zhou, Z.; Tang, J.; Miao, Y.; Zheng, M.; Wang, W.; Shen, Y., Terminating the criminal collaboration in pancreatic cancer: Nanoparticle-based synergistic therapy for overcoming fibroblast induced drug resistance. Biomaterials 2017, 144, 105-118.
26. Shao, S.; Zhou, Q.; Si, J.; Tang, J.; Liu, X.; Wang, M.; Gao, J.; Wang, K.; Xu, R.; Shen, Y., A non-cytotoxic dendrimer with innate and potent anticancer and anti-metastatic activities. Nature Biomedical Engineering 2017, 1 (9), 745-757.
27. Qiu, N.; Liu, X.; Piao, Y.; Zhou, Z.; Tang, J.; Shen, Y., Esterase responsive charge-reversal vectors for gene delivery and therapy. Journal of Controlled Release 2017, 259, E100-E100.
28. Zhou, X.; Liu, X.; Zhu, D.; Zhou, Z.; Tang, J.; Liu, X.; Shen, Y., Improving the gene transfection efficiency of polyethylenimine (PEI) based polyplex nanoparticles by cell cycle regulation. Nanomedicine-Nanotechnology Biology and Medicine 2016, 12 (2), 473-473.
29. Zhou, X.; Liu, X.; Zhao, B.; Liu, X.; Zhu, D.; Qiu, N.; Zhou, Q.; Piao, Y.; Zhou, Z.; Tang, J.; Shen, Y., Jumping the nuclear envelop barrier: Improving polyplex-mediated gene transfection efficiency by a selective CDKI inhibitor RO-3306. Journal of Controlled Release 2016, 234, 90-97.
30. Zhou, Q.; Liu, X.; Tang, J.; Shen, Y., Improving the antitumor efficacy of doxorubicin-loaded PEG-PCL copolymer micelles by down-regulating hedgehog pathway. Nanomedicine-Nanotechnology Biology and Medicine 2016, 12 (2), 471-471.
31. Zhang, Z.; Tang, J.; Liu, X.; Shen, Y., Synthesis and characterization of phosphate structured dendrimers as drug delivery carriers. Nanomedicine-Nanotechnology Biology and Medicine 2016, 12 (2), 473-473.
32. Yu, B.; Chi, M.; Han, Y.; Cong, H.; Tang, J.; Peng, Q., Self-assembled and covalently linked capillary coating of diazoresin and cyclodextrin-derived dendrimer for analysis of proteins by capillary electrophoresis. Talanta 2016, 152, 76-81.
33. You, C.; Shao, S.; Tang, J.; Liu, X.; Shen, Y., Antitumor activity of PEG-PCL/dithiocarbamate-copper nanoparticles. Nanomedicine-Nanotechnology Biology and Medicine 2016, 12 (2), 472-472.
34. Ye, M.; Wang, X.; Tang, J.; Guo, Z.; Tian, H.; Zhu, W.; Shen, Y., A dual fluorescent prodrug for in vivo tumor imaging and therapy. Nanomedicine-Nanotechnology Biology and Medicine 2016, 12 (2), 472-472.
35. Ye, M.; Wang, X.; Tang, J.; Guo, Z.; Shen, Y.; Tian, H.; Zhu, W.-H., Dual-channel NIR activatable theranostic prodrug for in vivo spatiotemporal tracking thiol-triggered chemotherapy. Chemical Science 2016, 7 (8), 4958-4965.
36. Xi, X.; Hu, S.; Zhou, Z.; Liu, X.; Tang, J.; Shen, Y., Dendrimers with the protocatechuic acid building block for anticancer drug delivery. Journal of Materials Chemistry B 2016, 4 (31), 5236-5245.
37. Wang, J.; Mao, W.; Lock, L. L.; Tang, J.; Sun, W.; Cui, H.; Xu, D.; Shen, Y., Polymeric prodrug micelles with tunable size probing the balance between tumor accumulation and penetration for cancer drug delivery. Nanomedicine-Nanotechnology Biology and Medicine 2016, 12 (2), 476-477.
38. Qiu, N.; Liu, X.; Zhong, Y.; Zhou, Z.; Piao, Y.; Miao, L.; Zhang, Q.; Tang, J.; Huang, L.; Shen, Y., Esterase-Activated Charge-Reversal Polymer for Fibroblast-Exempt Cancer Gene Therapy. Advanced Materials 2016, 28 (48), 10613-+.
39. Qiu, N.; Liu, X.; Tang, J.; Zhou, Z.; Shen, Y., CDDP treatment promoting tumor growth and metastasis. Nanomedicine-Nanotechnology Biology and Medicine 2016, 12 (2), 467-468.
40. Mao, X.; Si, J.; Huang, Q.; Sun, X.; Zhang, Q.; Shen, Y.; Tang, J.; Liu, X.; Sui, M., Self-Assembling Doxorubicin Prodrug Forming Nanoparticles and Effectively Reversing Drug Resistance In Vitro and In Vivo. Advanced Healthcare Materials 2016, 5 (19), 2517-2527.
41. Liu, X.; Xiang, J.; Zhu, D.; Jiang, L.; Zhou, Z.; Tang, J.; Liu, X.; Huang, Y.; Shen, Y., Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery. Advanced Materials 2016, 28 (9), 1743-1752.
42. Liu, X.; Tang, J.; Liu, X.; Shen, Y., Phenylboronic acid modified charge-reversal vectors for gene delivery. Nanomedicine-Nanotechnology Biology and Medicine 2016, 12 (2), 466-466.
43. Hu, H.; Sheng, Y.; Ye, M.; Qian, Y.; Tang, J.; Shen, Y., A porphyrin-based magnetic and fluorescent dual-modal nanoprobe for tumor imaging. Polymer 2016, 88, 94-101.
44. Han, Y.; Qian, Y.; Zhou, X.; Hu, H.; Liu, X.; Zhou, Z.; Tang, J.; Shen, Y., Facile synthesis of zwitterionic polyglycerol dendrimers with a beta-cyclodextrin core as MRI contrast agent carriers. Polymer Chemistry 2016, 7 (41), 6354-6362.
45. Zhu, D.; Tang, J.; Shen, Y., Zwitterionic poly(lysine methacrylate) brush as an effective carrier for drug delivery. Journal of Controlled Release 2015, 213, E27-E28.
46. Zhou, Z.; Tang, J.; Sun, Q.; Murdoch, W. J.; Shen, Y., A multifunctional PEG-PLL drug conjugate forming redox-responsive nanoparticles for intracellular drug delivery. Journal of Materials Chemistry B 2015, 3 (38), 7594-7603.
47. Ye, M.; Tang, J.; Sui, M.; Liu, X.; Shen, Y., In vitro inhibition of cancer stem cells by biguanidine-based macromolecular drug. Journal of Controlled Release 2015, 213, E79-E79.
48. Wang, T.; Zeng, Q.; Tang, J.; Sui, M.; Liu, X.; Shen, Y., A tumor-targeting MRI contrast agent based on hypoxia and pH-responsive nanogel. Journal of Controlled Release 2015, 213, E104-E105.
49. Wang, J.; Mao, W.; Lock, L. L.; Tang, J.; Sui, M.; Sun, W.; Cui, H.; Xu, D.; Shen, Y., The Role of Micelle Size in Tumor Accumulation, Penetration, and Treatment. Acs Nano 2015, 9 (7), 7195-7206.
50. Qiu, N.; Liu, X.; Sui, M.; Tang, J.; Shen, Y., Paclitaxel improved gene transfection efficiency through cell synchronization in SW480 cells. Journal of Controlled Release 2015, 213, E83-E83.
51. Liu, X.; Wang, J.; Shen, Y.; Tang, J.; Sui, M., Amphiphilic block copolymer of SN38 prodrugs by atom transfer radical polymerization: Synthesis, kinetic studies and self-assembly. Journal of Controlled Release 2015, 213, E124-E124.
52. Liu, X.; Sui, M.; Tang, J.; Shen, Y., A novel brush-shaped copolymer for drug delivery. Journal of Controlled Release 2015, 213, E120-E120.
53. Hu, S.; Shen, Y.; Tang, J.; Sui, M.; Liu, X., A theoretical hypothesis on co-precipitation of hydrophobic antitumor drug and amphiphilic block copolymers. Journal of Controlled Release 2015, 213, E98-E99.
54. Hu, S.; Lee, E.; Wang, C.; Wang, J.; Zhou, Z.; Li, Y.; Li, X.; Tang, J.; Lee, D. H.; Liu, X.; Shen, Y., Amphiphilic drugs as surfactants to fabricate excipient-free stable nanodispersions of hydrophobic drugs for cancer chemotherapy. Journal of Controlled Release 2015, 220, 175-179.
55. Han, Y.; Ye, M.; Tang, J.; Sui, M.; Liu, X.; Shen, Y., Synthesis and properties of zwitterionic dendrimer as drug and imaging probe carrier. Journal of Controlled Release 2015, 213, E144-E145.
56. Han, Y.; Ye, M.; Qian, Y.; Hu, H.; Tang, J.; Sui, M.; Liu, X.; Shen, Y., Facile synthesis of antifouling dendrimer for drug and bioprobe delivery. Abstracts of Papers of the American Chemical Society 2015, 249.
57. Chen, W. e.; Han, Y.; Qian, Y. e.; Tang, J.; Hu, H.; Shen, Y., Preparation and Imaging Study of Tumor-targeting MRI Contrast Agent Based on Fe3O4 Nanoparticles. Chemistry Letters 2015, 44 (12), 1771-1773.
58. Wu, X.; Sun, X.; Guo, Z.; Tang, J.; Shen, Y.; James, T. D.; Tian, H.; Zhu, W., In Vivo and in Situ Tracking Cancer Chemotherapy by Highly Photostable NIR Fluorescent Theranostic Prodrug. Journal of the American Chemical Society 2014, 136 (9), 3579-3588.
59. Shao, S.; Si, J.; Tang, J.; Sui, M.; Shen, Y., Jellyfish-Shaped Amphiphilic Dendrimers: Synthesis and Formation of Extremely Uniform Aggregates. Macromolecules 2014, 47 (3), 916-921.
60. Li, T.; Qian, Y.; Ye, M.; Tang, J.; Hu, H.; Shen, Y., Synthesis and Properties of a Biodegradable Dendritic Magnetic Resonance Imaging Contrast Agent. Chinese Journal of Chemistry 2014, 32 (1), 91-96.
61. Zhou, Z.; Ma, X.; Jin, E.; Tang, J.; Sui, M.; Shen, Y.; Van Kirk, E. A.; Murdoch, W. J.; Radosz, M., Linear-dendritic drug conjugates forming long-circulating nanorods for cancer-drug delivery. Biomaterials 2013, 34 (22), 5722-5735.
62. Ye, M.; Qian, Y.; Tang, J.; Hu, H.; Sui, M.; Shen, Y., Targeted biodegradable dendritic MRI contrast agent for enhanced tumor imaging. Journal of Controlled Release 2013, 169 (3), 239-245.
63. Ye, M.; Qian, Y.; Tang, J.; Hu, H.; Sui, M.; Shen, Y., Targeted biodegradable dendritic MRI contrast agent for enhanced tumor imaging (vol 169, pg 239, 2013). Journal of Controlled Release 2013, 172 (1), 258-258.
64. Wu, X.; Chang, S.; Sun, X.; Guo, Z.; Li, Y.; Tang, J.; Shen, Y.; Shi, J.; Tian, H.; Zhu, W., Constructing NIR silica-cyanine hybrid nanocomposite for bioimaging in vivo: a breakthrough in photo-stability and bright fluorescence with large Stokes shift. Chemical Science 2013, 4 (3), 1221-1228.
65. Wang, K.; Mao, W.; Sui, M.; Tang, J.; Shen, Y., Biodegradable charge-reversal PEI derivative for gene transfection. Journal of Controlled Release 2013, 172 (1), E109-E110.
66. Wang, J.; Sun, X.; Mao, W.; Sun, W.; Tang, J.; Sui, M.; Shen, Y.; Gu, Z., Tumor Redox Heterogeneity-Responsive Prodrug Nanocapsules for Cancer Chemotherapy. Advanced Materials 2013, 25 (27), 3670-3676.
67. Tang, J.; Sheng, Y.; Hu, H.; Shen, Y., Macromolecular MRI contrast agents: Structures, properties and applications. Progress in Polymer Science 2013, 38 (3-4), 462-502.
68. Sun, X.; Chen, Z.; Sui, M.; Tang, J.; Shen, Y., Parallel synthesis of polymers from epoxy-amine reaction for gene delivery. Journal of Controlled Release 2013, 172 (1), E118-E118.
69. Shen, Y.; Wang, J.; Tang, J.; Sui, M., Translational nanomedicine from self-assembling prodrugs. Abstracts of Papers of the American Chemical Society 2013, 246.
70. Ma, X.; Zhou, Z.; Jin, E.; Sun, Q.; Zhang, B.; Tang, J.; Shen, Y., Facile Synthesis of Polyester Dendrimers as Drug Delivery Carriers. Macromolecules 2013, 46 (1), 37-42.
71. Ma, X.; Sun, Q.; Zhou, Z.; Jin, E.; Tang, J.; Van Kirk, E.; Murdoch, W. J.; Shen, Y., Synthesis of degradable bifunctional dendritic polymers as versatile drug carriers. Polymer Chemistry 2013, 4 (3), 812-819.
72. Jin, E.; Zhang, B.; Sun, X.; Zhou, Z.; Ma, X.; Sun, Q.; Tang, J.; Shen, Y.; Van Kirk, E.; Murdoch, W. J.; Radosz, M., Acid-Active Cell-Penetrating Peptides for in Vivo Tumor-Targeted Drug Delivery. Journal of the American Chemical Society 2013, 135 (2), 933-940.
73. Gou, P.; Liu, W.; Mao, W.; Tang, J.; Shen, Y.; Sui, M., Self-assembling doxorubicin prodrug forming nanoparticles for cancer chemotherapy: synthesis and anticancer study in vitro and in vivo. Journal of Materials Chemistry B 2013, 1 (3), 284-292.
74. Ye, M.; Qian, Y.; Shen, Y.; Hu, H.; Sui, M.; Tang, J., Facile synthesis and in vivo evaluation of biodegradable dendritic MRI contrast agents. Journal of Materials Chemistry 2012, 22 (29), 14369-14377.
75. Yang, J.; Sun, X.; Mao, W.; Sui, M.; Tang, J.; Shen, Y., Conjugate of Pt(IV)-Histone Deacetylase Inhibitor as a Prodrug for Cancer Chemotherapy. Molecular Pharmaceutics 2012, 9 (10), 2793-2800.
76. Wang, J.; Zhang, H.; Tang, J.; Sui, M.; Shen, Y., Produg nanoparticles: Structural parameters affecting pharmacokinetics. Abstracts of Papers of the American Chemical Society 2012, 243.
77. Lu, K.; Cao, M.; Mao, W.; Sun, X.; Tang, J.; Shen, Y.; Sui, M., Targeted acid-labile conjugates of norcantharidin for cancer chemotherapy. Journal of Materials Chemistry 2012, 22 (31), 15804-15811.
78. Zhou, Z.; Shen, Y.; Tang, J.; Jin, E.; Ma, X.; Sun, Q.; Zhang, B.; Van Kirk, E. A.; Murdoch, W. J., Linear polyethyleneimine-based charge-reversal nanoparticles for nuclear-targeted drug delivery. Journal of Materials Chemistry 2011, 21 (47), 19114-19123.
79. ZhongChun, C.; JianBin, T.; YouQing, S.; XinPing, W., 'Click synthesis' of topological macromolecules. Scientia Sinica Chimica 2011, 41 (2), 281-303.
80. Ye, M.; Tang, J.; Wang, X.; Xu, J.; Sui, M.; Shen, Y., Synthesis and characterization of a novel dendritic magnetic resonance imaging contrast agent. Journal of Controlled Release 2011, 152, E256-E257.
81. Yang, J.; Mao, W.; Sui, M.; Tang, J.; Shen, Y., Platinum (IV)-coordinate polymers for cancer drug delivery. Journal of Controlled Release 2011, 152, E108-E109.
82. Yang, J.; Liu, W.; Sui, M.; Tang, J.; Shen, Y., Platinum (IV)-coordinate polymers as intracellular reduction-responsive backbone-type conjugates for cancer drug delivery. Biomaterials 2011, 32 (34), 9136-9143
83. Xu, C.-h.; Sui, M.-h.; Tang, J.-b.; Shen, Y.-q., What can we learn from virus in designing nonviral gene vectors. Chinese Journal of Polymer Science 2011, 29 (3), 274-287.
84. Wang, X.; Tang, J.; Sui, M.; Wang, X.; Xu, J.; Shen, Y., Degradable water soluble hyperbranched polymers for drug delivery. Journal of Controlled Release 2011, 152, E76-E78.
85. Tang, J.; Wang, X.; Wang, X.; Sui, M.; Mao, W.; Shen, Y., beta-Cyclodextrin-based biodegradable dendrimers for drug delivery. Journal of Controlled Release 2011, 152, E89-E90.
86. Sun, X.-m.; Xu, J.-x.; Tang, J.-b.; Sui, M.-h.; Shen, Y.-q., Folate-targeted optical and magnetic resonance dualmodality PCL-b-PEG micelles for tumor imaging. Chinese Journal of Polymer Science 2011, 29 (4), 427-430.
87. Shen, Y.; Ma, X.; Zhang, B.; Zhou, Z.; Sun, Q.; Jin, E.; Sui, M.; Tang, J.; Wang, J.; Fan, M., Degradable Dual pH- and Temperature-Responsive Photoluminescent Dendrimers. Chemistry-a European Journal 2011, 17 (19), 5319-5326.
88. Shen, Y.; Zhou, Z.; Sui, M.; Tang, J.; Xu, P.; Van Kirk, E. A.; Murdoch, W. J.; Fan, M.; Radosz, M., Charge-reversal polyamidoamine dendrimer for cascade nuclear drug delivery. Nanomedicine 2010, 5 (8), 1205-1217.
89. Shen, Y.; Jin, E.; Zhang, B.; Murphy, C. J.; Sui, M.; Zhao, J.; Wang, J.; Tang, J.; Fan, M.; Van Kirk, E.; Murdoch, W. J., Prodrugs Forming High Drug Loading Multifunctional Nanocapsules for Intracellular Cancer Drug Delivery. Journal of the American Chemical Society 2010, 132 (12), 4259-4265.
90. Zhou, Z.; Shen, Y.; Tang, J.; Fan, M.; Van Kirk, E. A.; Murdoch, W. J.; Radosz, M., Charge-Reversal Drug Conjugate for Targeted Cancer Cell Nuclear Drug Delivery. Advanced Functional Materials 2009, 19 (22), 3580-3589.
91. Zhang, L.; Tang, H.; Tang, J.; Shen, Y.; Meng, L.; Radosz, M.; Arulsamy, N., Pentadentate Copper Halide Complexes Have Higher Catalytic Activity in Atom Transfer Radical Polymerization of Methyl Acrylate Than Hexadentate Complexes. Macromolecules 2009, 42 (13), 4531-4538.
92. Xu, J.-x.; Tang, J.-b.; Zhao, L.-h.; Shen, Y.-q., Advances in the study of tumor pH-responsive polymeric micelles for cancer drug targeting delivery. Yaoxue Xuebao 2009, 44 (12), 1328-1335.
93. Tang, J.; Shen, Y.; Radosz, M.; Sun, W., Isothermal Carbon Dioxide Sorption in Poly(ionic liquid)s. Industrial & Engineering Chemistry Research 2009, 48 (20), 9113-9118.
94. Ma, X.; Tang, J.; Shen, Y.; Fan, M.; Tang, H.; Radosz, M., Facile Synthesis of Polyester Dendrimers from Sequential Click Coupling of Asymmetrical Monomers. Journal of the American Chemical Society 2009, 131 (41), 14795-14803.
95. Zhou, Z.; Sun, W.; Tang, J.; Shen, Z., Synthesis of novel copolymers containing tri(ethylene oxide) segments and bithiazole rings on the backbone and magnetic properties of their complexes. Polymer 2006, 47 (18), 6280-6284.
96. Tang, J.; Sun, W.; Radosz, M.; Shen, Y., Poly(ionic liquid)s as microwave absorption materials. Abstracts of Papers of the American Chemical Society 2006, 231.
97. Tang, J.; Sun, W.; Radosz, M.; Shen, Y., CO2 sorption of poly(ionic liquid)s. Abstracts of Papers of the American Chemical Society 2006, 231.
98. Hu, X.; Tang, J.; Blasig, A.; Shen, Y.; Radosz, M., CO2 permeability, diffusivity and solubility in polyethylene glycol-grafted polyionic membranes and their CO2 selectivity relative to methane and nitrogen. Journal of Membrane Science 2006, 281 (1-2), 130-138.
99. Zhou, Z. X.; Sun, W. L.; Yang, J.; Tang, J. B.; Shen, Z. Q., Synthesis and properties of novel fully conjugated polymers containing bithiazole rings. Polymer 2005, 46 (22), 9495-9500.
100. Tang, J. B.; Tang, H. D.; Sun, W. L.; Radosz, M.; Shen, Y. Q., Poly(ionic liquid)s: Novel materials for CO2 absorption. Abstracts of Papers of the American Chemical Society 2005, 229, U1162-U1162.
101. Tang, J. B.; Tang, H. D.; Sun, W. L.; Radosz, M.; Shen, Y. Q., Poly(ionic liquid)s as new materials forCO(2) absorption. Journal of Polymer Science Part a-Polymer Chemistry 2005, 43 (22), 5477-5489.
102. Tang, J. B.; Tang, H. D.; Sun, W. L.; Radosz, M.; Shen, Y. Q., Low-pressure CO2 sorption in ammonium-based poly(ionic liquid)s. Polymer 2005, 46 (26), 12460-12467.
103. Tang, J. B.; Tang, H. D.; Sun, W. L.; Plancher, H.; Radosz, M.; Shen, Y. Q., Poly(ionic liquid)s: a new material with enhanced and fast CO2 absorption. Chemical Communications 2005, (26), 3325-3327.
104. Tang, J. B.; Sun, W. L.; Tang, H. D.; Radosz, M.; Shen, Y. Q., Enhanced CO2 absorption of poly(ionic liquid)s. Macromolecules 2005, 38 (6), 2037-2039.
105. Tang, J.; Tang, H.; Sun, W.; Radosz, M.; Shen, Y., Carbon dioxide absorption of poly(ionic liquid)s with different ionic structures. Abstracts of Papers of the American Chemical Society 2005, 230, U3777-U3777.
106. Shen, Y. Q.; Tang, J. B.; Tang, H. D.; Sun, W. L.; Radosz, M., CO2 absorption of polymers of ammonium-based ionic liquid monomers. Abstracts of Papers of the American Chemical Society 2005, 229, U1107-U1107.
107. Tang, J. B.; Tang, H. D.; Radosz, M.; Sun, W. L.; Shen, Y. Q., Copolymerization of ionic liquid monomers with styrene and methyl methacrylate. Abstracts of Papers of the American Chemical Society 2004, 228, U493-U493.
108. Tang, J. B.; Jiang, L. M.; Sun, W. L.; Shen, Z. Q., Synthesis of poly(thiazole-2,4-diyl)-rare-earth complexes and their magnetic properties. Reactive & Functional Polymers 2004, 61 (3), 405-410.
109. Sun, W. L.; Liu, S. A.; He, B. J.; Tang, J. B.; Shen, Z. Q., New magnetic phenomena of rare earth polymeric complexes. Physics Letters A 2004, 328 (6), 463-466.
出版著作
Jianbin Tang, Dingcheng Zhu, Shen Youqing. Self-assembly of polymers into soft nanoparticles and nanocapsules, 3541-3560. in book 《Supramolecular Chemistry: From Molecules to Nanomaterials》Volume 7: Soft Matter. 2012 John Wiley & Sons. LtD.
專利成果
申有青;唐建斌;孫曉明
CN200910100118.0
一種聚酯樹枝狀大分子的製備方法
申有青;唐建斌;隋梅花;徐春紅
CN200910102143.2
喜樹鹼及其衍生物的自乳化藥物前體及其套用
申有青;唐建斌;隋梅花;黃金強
CN200910101386.4
一種薑黃素聚合物的製備方法
申有青;唐建斌;苟鵬飛;隋梅花
CN201110113954.X
一種自乳化阿黴素納米藥物及其製備方法
申有青;王金強;唐建斌;隋梅花
CN201010561727.9
7-乙基-10-羥基喜樹鹼的兩親性藥物前體及其製備方法
唐建斌;餘波;申有青;潘帥
CN201010538144.4
無銀抗菌供水管及其生產方法
榮譽獎項
2012年 國家自然科學基金委第二屆化學工程青年 科學家學術交流研討會 優秀論文獎
2019年 生物材料學會科學技術獎二等獎（排名第二）
