唐凱臨

唐凱臨，女，博士，同濟大學生命科學與技術學院副教授、碩士生導師。

基本介紹

  • 中文名：唐凱臨
  • 畢業院校：同濟大學
  • 學位/學歷：博士
  • 專業方向：中藥信息學、小分子組效關係、靶點分類預測；藥物作用機理分析
  • 職務：碩士生導師
人物經歷,科研項目,專利,發表論文,

人物經歷

現任同濟大學轉化醫學高等研究院副研究員。1999年畢業於同濟大學化學系。2007年畢業於同濟大學化學系，獲博士學位。2007-2013年在上海生物信息技術研究中心，副研究員。2013年至今在同濟大學生命科學與技術學院從事教學和科研工作。2012年至今兼任上海理工大學聯合培養碩士生導師。

科研項目

1．國家自然科學基金（編號：30900832）
2．上海中醫藥大學肝腎疾病病症重點實驗室開放基金項目
3.科技部863（編號：2012AA020404）
4.國家自然科學基金（編號：20675057；20705024）

專利

曹志偉，葉浩，唐凱臨，李亦學，一種基於生物過程預測藥物新療效的方法及套用。

發表論文

  1. Qi T, Qiu T, Zhang Q, Tang K, Fan Y, Qiu J, Wu D, Zhang W, Chen Y, Gao J, Zhu R, Cao Z，SEPPA 2.0—more refined server to predict spatial epitope considering species of immune host and subcellular localization of protein antigen，Nucl. Acids Res. 2014，42 (W1): W59-W63.
  2. Peng Fu, Linlin Yang, Yi Sun, Li Ye, Zhiwei Cao and Kailin Tang*，Target network differences between western drugs and Chinese herbal ingredients in treating cardiovascular disease，BMC Bioinformatics 2014, 15(Suppl 4):S3
  3. Haoqi Sun, Haiping Wang, Ruixin Zhu, Kailin Tang, Qin Gong, Juan Cui, Zhiwei Cao,Qi Liu，iPEAP: integrating multiple omics and genetic data for pathway enrichment analysis，Bioinformatics，2014，30(5): 737-739
  4. Hong Kang, Kailin Tang, Qi Liu, Yi Sun, Qi Huang, Ruixin Zhu, Jun Gao, Duanfeng Zhang, Chenggang Huang and Zhiwei Cao, HIM-herbal ingredients in-vivo metabolism database, 2013, Journal of Cheminformatics, 2013, 5:28
  5. Chao Ma, Kailin Tang, Qi Liu, Ruixin Zhu, Zhiwei Cao, Calmodulin as a Potential Target by Which Berberine Induces Cell Cycle Arrest in Human Hepatoma Bel7402 Cells, Chemical Biology & Drug Design, 2013, 81(6):775–783
  6. Yi Sun, Ruixin Zhu, Hao Ye, Kailin Tang, Jing Zhao, Yujia Chen, Qi Liu and Zhiwei Cao, Towards a bioinformatics analysis of anti-Alzheimer’s herbal medicines from a target network perspective, Briefings in Bioinformatics, 2013, 14(3):327-43
  7. 劉雪平, 楊琳琳, 付鵬, 唐凱臨*, 曹志偉*，活血化瘀中藥抗肝纖維化作用計算藥理探討，生物物理學報，2012, 28(12)：971-982
  8. Linlin Yang*, Kailin Tang*, Ying Qi, Hao Ye, Wenlian Chen, Yongyu Zhang, Zhiwei Cao. Potential metabolic mechanism of girls’central precocious puberty: a network analysis on urine Metabonomics data.BMC Systems Biology 2012, 6(Suppl 3):S19
  9. 楊琳琳，葉浩，唐凱臨*，曹志偉*. 基於靶基因比較MicroRNAs與HBV蛋白的作用模式. 科學通報,2012, 57(19), 1755-1762
  10. Hao Ye, Kailin Tang, Linlin Yang, Zhiwei Cao, Yixue Li，Study of drug function based on similarity of pathway fingerprint，Protein & Cell，2012, 3(2): 132–139
  11. YE Hao, YANG LinLin, CAO ZhiWei, TANG KaiLin, LI Yixue, A pathway profile-based method for drug repositioning，Chinese Science Bulletin, 2012，57(17): 2106-2112
  12. YE Li, YE Hao, LIU XuePing, YANG LinLin, CAO ZhiWei, TANG KaiLin*, Pathway-Pathway Network Based Study on the Therapeutic Mechanisms of Salvianolic acid B Regulates cardiovascular diseases, Chinese Science Bulletin, 2012，57(14): 1672-1679
  13. Li-Xing Feng, Chun-Jie Jing，Kai-Lin Tang，Lin Tao，Zhi-Wei Cao，Wan-Ying Wu，Shu-Hong Guan，Bao-Hong Jiang，Min Yang，Xuan Liu，De-An Guo, Clarifying the signal network of salvianolic acid B using proteomic assay and bioinformatic analysis, PROTEOMICS, 2011, Volume 11, Issue 8, 1473-1485
  14. Tang K, Zhu R, Li Y, Cao Z. Discrimination of Approved Drugs from Experimental Drugs by Learning Methods, BMC Bioinformatics 2011, 12:157
  15. Ye H, Ye L, Kang H, Zhang D, Tao L, Tang K, Liu X, Zhu R, Liu Q, Chen YZ, Li Y, Cao Z. HIT: linking herbal active ingredients to targets, Nucleic Acids Research, 2011, Vol. 39, D1055–D1059
  16. Tang KL, Yao WJ, Li TH, Li YX, Cao ZW. Cancer Classification from The Gene Expression Profiles By Discriminant Kernel-PLS, Journal of Bioinformatics and Computational Biology, Vol. 8, S1 (2010) 147–160
  17. Zhao, J; Geng, C; Tao, L; Zhang, DF; Jiang, Y; Tang, KL; Zhu, RX; Yu, H; Zhang, WD; He, FC; Li, YX; Cao, ZW Reconstruction and Analysis of Human Liver-Specific Metabolic Network Based on CNHLPP Data, Journal of Proteome Research, 2010, 9, 1648–1658
  18. Tang KL, Li TH, Xiong WW, Chen K. Ovarian cancer classification based on dimensionality reduction for SELDI-TOF data. BMC Bioinformatics. 2010 Feb 27;11:109
  19. Wenwei Xiong, Tonghua Li, Kai Chen, and Kailin Tang，Local combinational variables: an approach used in DNA-binding helix-turn-helix motif prediction with sequence information，Nucleic Acids Res. 2009, 37(17): 5632–5640
  20. Kai-lin TANG, Tong-hua LI，Kai CHEN，QSAR Studies on PCDD/Fs by Kernel PLS，Chemical Research in Chinese Universities，Volume 24, Issue 5, 2008, 541-545
  21. 唐凱臨，李通化，陳開, 多肽保留時間預測的研究, 計算機與套用化學，2008，vol25，No.2，145-147
  22. Kailin Tang, Tonghua Li, Kai Chen, Jinyan Huang, Application of kernel method to classify SELDI-TOF proteomics data, Computers and Applied Chemistry, 2007,Vol.24,No.1, 107-109
  23. Kailin Tang, Tonghua Li, Comparison of different partial least-squares methods in quantitative structure–activity relationships, Analytica Chimica Acta 476 (2003) 85-92
  24. Kailin Tang, Tonghua Li, Combining PLS with GA-GP for QSAR, Chemometrics and Intelligent Laboratory Systems 64 (2002) 55-64

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