周華鵬(四川大學生命科學學院副教授)

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基本介紹

  • 中文名:周華鵬
  • 國籍中國
  • 學位/學歷:博士 
  • 職稱:副教授 
  • 研究方向:植物逆境生物學 
主講課程,研究方向,學術成果,

主講課程

《植物逆境分子生物學》(本科生)
《食品生物技術與飲食健康》(本科生)
《微觀生物學》[植物逆境生物學板塊](研究生)

研究方向

(1)通過正向/反向遺傳學手段篩選鑑定調節植物應對鹽脅迫等逆境新的調節因子與調控原件,著重解析植物對逆境脅迫的應答與耐受過程的信號調控網路
(2)以小立碗蘚為模式植物,解析初級陸生植物的逆境應答機制與高等植物的異同。

學術成果

(1)發現去泛素化酶(Ubiqutin-Specific Protease, UBP)家族成員介導的蛋白質去泛素化修飾過程對植物耐鹽性、抗旱性及脫落酸信號途徑等具有重要調節作用;(2)結合蛋白質組學、分子生物學及生物化學等多種研究手段,闡明了通用調節因子(General regulatory factor,GRF)14-3-3蛋白參與調節植物耐鹽性的分子機制。先後分別以第一作者或通訊作者身份將相關研究成果發表於植物學國際頂級期刊The Plant Cell(2012年、2014年)及植物學國際權威期刊Plant Cell and Environment(2015年)、Plant Molecular Biology(2016年、2017年)、Plant and Cell Physiology(2017年)、Journal of Integrative Plant Biology(2017年)、Frontiers in Plant Science(2017年)、PLoS Genetics(2018年)等雜誌上,其中部分成果被Cell、Trends in Plant Science等國際頂級綜述文章引用。相關研究成果為進一步理解植物的抗逆性等提供了新的證據,對於遺傳改良作物、提高其抗逆能力等具有重要的科學指導意義。
已發表文章
(1)Zhou, H., Zhao, J., Yang, Y., Chen, C., Liu, Y., Jin, X., ... & Guo, Y. (2012). UBIQUITIN-SPECIFIC PROTEASE16 Modulates Salt Tolerance in Arabidopsis by Regulating Na/H Antiport Activity and Serine Hydroxymethyltransferase Stability. The Plant Cell, 24(12), 5106-5122.
(2)Zhao, J.,Zhou, H., & Li, X. (2013).Ubiquitin-specific protease16 interacts with a heavy metal associated isoprenylated plant protein27 and modulates cadmium tolerance. Plant signaling & behavior 8(10). DOI 10.4161/psb.25680.
(3)Zhou, H., Lin, H., Chen, S., Becker, K., Yang, Y., Zhao, J., ... & Guo, Y. (2014). Inhibition of the Arabidopsis Salt Overly Sensitive Pathway by 14-3-3 Proteins. The Plant Cell, 26(3), 1166-1182.
(4)Zhao, J., Zhou, H., Zhang, M., Gao, Y., Li, L., Gao, Y., ... & Li, X. (2016). Ubiquitin-specific protease 24 negatively regulates abscisic acid signalling in Arabidopsis thaliana. Plant Cell and Environment, 39(2), 427-440.[#,並列一作]
(5)Tan, T., Cai, J., Zhan, E., Yang, Y., Zhao, J., Guo, Y., &Zhou, H. (2016). Stability and localization of 14-3-3 proteins are involved in salt tolerance in Arabidopsis. Plant Molecular Biology, 92(3), 391-400.
(6)Zhou, H., Zhao, J., Cai, J., & Patil, SB. (2017).UBIQUITIN-SPECIFIC PROTEASES function in plant development and stress responses. Plant Molecular Biology, 94(6), 565-576.
(7)Tan, T., Sun, Y., Peng, X., Wu, G., Bao, F., ...Zhou, H., & Lin, H. (2017). ABSCISIC ACID INSENSITIVE3 Is Involved in Cold Response and Freezing Tolerance Regulation in Physcomitrella patens. Frontiers in Plant Science 8:1599. DOI 10.3389/fpls.2017.01599.[*,通訊作者]
(8)Tan, T., Sun, Y., Luo, S., Zhang, C.,Zhou, H., & Lin, H.(2017). Efficient modulation of photosynthetic apparatus confers desiccation tolerance in the resurrection plant Boea hygrometrica. Plant and Cell Physiology 58(11), 1976-1990.[*,通訊作者]
(9)Zhan, E., Zhou, H., Li, Sha., Liu, L., Tan, T., & Lin, H. (2017). OTS1-dependent DeSUMOylation Increases Tolerance to High Copper Levels in Arabidopsis. Journal of Integrative Plant Biology,DOI 10.1111/jipb.12618.[#,並列一作;*,通訊作者]
(10)Tan W., Zhang D., Zhou H., Zheng T., Yin Y., Lin H. (2018). Transcription factor HAT1 is a substrate of SnRK2.3 kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought. PLoS Genetics, 14(4), 1-27. [#,並列一作]
(11)Zhou H., Wang C., Tan T., Cai J., He J., Lin H. (2018). Patellin1 negatively modulates salt tolerance by regulating PM Na+/H+ antiport activity and cellular redox homeostasis in Arabidopsis. Plant & Cell Physiology, 59(8), 1630-1642. [*,通訊作者]
(12)Zhou H., Duan H., Liu Y., Sun X., Zhao J., Lin H. (2019). Patellin protein family functions in plant development and stress response. Journal of Plant Physiology, 234-235, 94-97. [*,通訊作者]

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