周洲，女，四川大學華西藥學院副教授。
人物經歷,研究方向,研究課題,代表性論著,
人物經歷
2009-2015 四川大學華西藥學院，獲藥劑學博士學位
2015- 四川大學華西藥鍵捆紙學院藥劑系任道才鍵講師、副教授
2018-2019 美國猶他大學藥學院訪問學者
研究方向
靶向給藥系統的構建及其作用機制研究
研究課題
1. 國家自然科學基金茅乘估企委員會，青年基金項目，81603042，“一靶多效”的腫瘤細胞線粒體內膜靶向的HPMA聚合物交聯膠束的構建與機制研究，2017至2019，主持。
2.四川省科技廳，重台符敬點研發項目，2018SZ0032，可靶向腫瘤細胞和腫瘤相關巨噬細胞的複合靶向遞藥系統研究，2018至2019，主持。
3.四川大學青年教師啟動基金，2016SCU11008，具有溶酶辨遙拳再體逃逸和細胞核靶向雙功能的膠束轎危給藥系統的求估妹研究，2016至2017，主持。
代表性論著
1. Liu, Yuanyuan#; Zhou, Zhou#; Lin, Xi; Xiong, Xiaofeng; Zhou, Rui; Zhou, Minglu; Huang, Yuan*. Enhanced Reactive Oxygen Species Generation by MitochondriaTargeting of Anticancer Drug To Overcome Tumor Multidrug Resistance, Biomacromolecules, 2019, 20(10): 3755-3766.
2. Yanxi Liu， Qiuyi Li， Xiaofeng Xiong， Zhou Zhou*. Improved mitochondrial targeting effect of HPMA copolymer by SS20 peptide mediation and nonendocytosis pathway, Journal of Peptide Science, 2019, 25(2): e3144.
3. Liu Yanxi; Li Qiuyi; Xiong Xiaofeng; Huang Yuan; Zhou Zhou*. Mitochondriatargeting and cell-penetrating peptides-co-modified HPMA copolymers for enhancing therapeutic efficacy of α-tocopheryl succinate, Journal of Materials, Chemistry B, 2018, 6(46): 7674-7683.
4. Yanxi Liu, Qiuyi Li, Xiaofeng Xiong, Yuan Huang and Zhou Zhou*. Enhanced cellular uptake by non-endocytic pathway for tumor therapy, Journal of Materials Chemistry B, 2018, 6(45): 7411-7419.
5. Wang, Fengling; Li, Lian; Sun, Wei; Li, Lijia; Liu, Yuanyuan; Huang, Yuan; Zhou, Zhou*. A novel alpha(V) beta(3) ligand-modified HPMA copolymers for anticancer drug delivery, Journal of Drug Targeting, 2018, 26(3): 231-241.
6. Zhou Zhou; Liu Yanxi; Wu Lei; Li Lian; Huang Yuan*. Enhanced nuclear delivery of anti-cancer drugs using micelles containing releasable membrane fusion peptide and nuclear-targeting retinoic acid, Journal of Materials Chemistry B, 2017, 5(34): 7175-7185.
7. Manling Tang, Minglu Zhou, Yuan Huang, Jiaju Zhong, Zhou Zhou* and Kui Luo*. Dual-sensitive and biodegradable core-crosslinked HPMA copolymer– doxorubicin conjugate-based nanoparticles for cancer therapy, Polymer Chemistry, 2017, 8(15): 2370-2380.
8. Zhou Zhou, Xiuli Xu, Lian Li, Yuan Huang*. Improvement of anti-tumor abilities on human non-small cell lung carcinoma by micellization and cross-linking of N- (2-hydroxypropyl) methacrylamide copolymers. Journal of Drug Targeting. 2015, 23(9): 821-831.
9. Zhou, Zhou; Li, Lian; Yang, Yang; Xu, Xiuli; Huang, Yuan*. Tumor targeting by pH-sensitive, biodegradable, cross-linked N-(2-hydroxypropyl) methacrylamide copolymer micelles, Biomaterials, 2014, 35(24): 6622-6635.
5. Wang, Fengling; Li, Lian; Sun, Wei; Li, Lijia; Liu, Yuanyuan; Huang, Yuan; Zhou, Zhou*. A novel alpha(V) beta(3) ligand-modified HPMA copolymers for anticancer drug delivery, Journal of Drug Targeting, 2018, 26(3): 231-241.
6. Zhou Zhou; Liu Yanxi; Wu Lei; Li Lian; Huang Yuan*. Enhanced nuclear delivery of anti-cancer drugs using micelles containing releasable membrane fusion peptide and nuclear-targeting retinoic acid, Journal of Materials Chemistry B, 2017, 5(34): 7175-7185.
7. Manling Tang, Minglu Zhou, Yuan Huang, Jiaju Zhong, Zhou Zhou* and Kui Luo*. Dual-sensitive and biodegradable core-crosslinked HPMA copolymer– doxorubicin conjugate-based nanoparticles for cancer therapy, Polymer Chemistry, 2017, 8(15): 2370-2380.
8. Zhou Zhou, Xiuli Xu, Lian Li, Yuan Huang*. Improvement of anti-tumor abilities on human non-small cell lung carcinoma by micellization and cross-linking of N- (2-hydroxypropyl) methacrylamide copolymers. Journal of Drug Targeting. 2015, 23(9): 821-831.
9. Zhou, Zhou; Li, Lian; Yang, Yang; Xu, Xiuli; Huang, Yuan*. Tumor targeting by pH-sensitive, biodegradable, cross-linked N-(2-hydroxypropyl) methacrylamide copolymer micelles, Biomaterials, 2014, 35(24): 6622-6635.
