周小明，男，1981年生，湖南邵陽人，華南師範大學生命科學學院研究員，博士生導師。
基本介紹
- 中文名：周小明
- 國籍：中國
- 出生日期：1981年
- 職業：教師
- 職稱：研究員
個人簡歷,教育經歷,工作經歷,研究方向,講授課程,承擔課題,論文專著,
個人簡歷
基於多學科背景，以交叉技術的角度開展生物、醫學分子診斷方法和技術的開發和套用研究工作。研究內容主要概括為：“基因檢測探針設計與構建、基因擴增方法、感測平台的研究及重大疾病核酸標誌物、病原微生物的定性和定量檢測套用”。研究成果在JACS, Angewandte Chemie, Nature Protocols, Nature Communications, ACS Nano, Chemical Society Reviews, Analytical Chemistry, Biomaterials, Theranostics, Lab on a Chip等期刊發表研究論文總計70多篇（截止目前被引用2800 余次）, H指數31。申請國家發明專利 18 項，目前已獲得授權 14 項。獲廣東省傑出青年基金、廣東省特支計畫（科技創新青年拔尖人才）、廣東省優秀青年教師基金、廣州市珠江科技新星等人才項目資助, 研究成果獲教育部自然科學二等獎。
獲聘《雷射生物學報》常務編委、《分析測試學報》青年編委、中國光學學會生物醫學光子學專委、中國生物醫學工程學會生物醫學光子學青委、廣東省生物醫學工程學位專委。 擔任《Nature Biomedical Engineering》,《Nucleic Acids Research》, 《ACS Nano》,《Clinical Chemistry》, 《Analytical Chemistry》, 《Advanced Science》, 《Biotechnology and Bioengineering》, 《Biosensors and Bioelectronics》, 《ACS Applied Materials & Interfaces》,《Nanoscale》,《Environmental Science & Technology》, 《Sensors & Actuators: B. Chemical》, 《Journal of Agricultural and Food Chemistry》,《Analytica Chimica Acta》, 《Analyst》等生物、化學、材料、環境、醫學領域權威刊物審稿人。
教育經歷
2014.9—2015.6，武漢大學，化學與分子科學學院，教育部青年骨幹訪問學者
2005.9—2010.7， 生物物理學博士，華南師範大學，博士（生物物理）
2001.9—2005.7， 生物科學學士，湖南文理學院，學士（生物科學）
工作經歷
2018.04-至今：華南師範大學，生命科學學院，分子生物醫學實驗室（建立者），研究員
2016.12—2018.04：華南師範大學，生物光子學研究院，雷射生命科學教育部重點實驗室，研究員
2015.6—2016.12：華南師範大學，生物光子學研究院，雷射生命科學教育部重點實驗室，特聘研究員
2013.1—2015.6：華南師範大學，生物光子學研究院，雷射生命科學教育部重點實驗室，副研究員
2010.7—2012.12：華南師範大學，生物光子學研究院，雷射生命科學教育部重點實驗室，講師
研究方向
基於多學科背景，以交叉技術的角度開展基因檢測中的“樣品處理、探針設計與合成、基因擴增方法、感測器構建及其在疾病診斷、動植物病原防疫、食源性有害微生物的分子診斷套用”研究工作。
講授課程
生物醫學工程概論，本科生生物製藥，本科生分子細胞生物學，研究生學科前沿進展，研究生
承擔課題
1. 國家自然科學基金-重大研究計畫（腫瘤演進與診療的分子功能可視化研究）：基於CRISPR/Cas識別原理的紙晶片研究及其在腫瘤基因突變、甲基化可視化檢測的套用，2020.01-2022.12，主持
2. 國家自然科學基金-面上項目：具有聚合活性三聯吡啶釕探針的構建及其在體外與原位分子診斷中的套用, 2019.1-2022.12，主持
3. 國家自然科學基金-面上項目：適配體靶向與轉運的功能化核酸探針構建及端粒酶活性調控與分析，2015.1-2018.12，主持
4. 國家自然科學基金-青年項目：基於單分子螢光光譜與核酸探針的均相生物感測新方法與技術研究，2012.1-2014.12，主持
5. 廣東省自然科學-傑出青年基金：重要病原微生物的核酸分子診斷新策略及新技術研究，2014.10-2018.10，主持
6. 廣東省特支計畫：科技創新青年拔尖人才項目，2015.10-2018.10，主持
7. 廣東省高等學校優秀青年教師培養對象，2015.1-2017.12，主持
8. 廣州市珠江科技新星：納米探針在人端粒酶生物學上的基礎研究：功能調控及活性檢測，2013.5-2016.6，主持
9. 廣東省自然科學基金：基於螢光相關光譜與適配體的均相生物感測新方法與技術研究，2011.10-2013.10，主持
論文專著
論文專著(#第一作者，*通訊作者)：
1. Huahua Yue, Bowen Shu,* Tian Tian, Erhu Xiong, Mengqi Huang, Debin Zhu, Jian Sun, Qing Liu, Shichan Wang, Yirong Li, and Xiaoming Zhou*, Droplet Cas12a Assay Enables DNA Quantifification from Unamplifified Samples at the Single-Molecule Level, Nano Letters, 2021, 21, 4643−4653.
2. Huahua Yue, Mengqi Huang, Tian Tian, Erhu Xiong, and Xiaoming Zhou*, Advances in Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)-Based Diagnostic Assays Assisted by Micro/Nanotechnologies, ACS Nano, 2021, 15, 7848−7859.
3. Wei Lin, Tian Tian, Yongzhong Jiang, Erhu Xiong, Debin Zhu*, Xiaoming Zhou*, A CRISPR/Cas9 eraser strategy for contamination‐free PCR end‐point detection, Biotechnology and Bioengineering, 2021, 118, 2053-2066.
4. Yongzhong Jiang, Menglu Hu, An-An Liu, Yi Lin, Linlin Liu, Bo Yu, Xiaoming Zhou*, and Dai-Wen Pang*, Detection of SARS-CoV-2 by CRISPR/Cas12a-Enhanced Colorimetry, ACS Sensors, 2021, 6(3),1086-1093.
5. Tian, Tian, Bowen Shu*, Yongzhong Jiang, Miaomiao Ye, Lei Liu, Zhang Wang, Zhonghui Guo, Zeping Han, Xiaoming Zhou*, An Ultralocalized Cas13a Assay Enables Universal and Nucleic Acid Amplification-Free Single-Molecule RNA Diagnostics, ACS Nano, 2021, 15, 1167−1178.
6. Erhu Xiong, Ling Jiang, Tian Tian, Menglu Hu, Huahua Yue, Mengqi Huang, Wei Lin, Yongzhong Jiang, Debin Zhu, and Xiaoming Zhou*, Simultaneous dual-gene diagnosis of SARS-CoV-2 based on CRISPR/Cas9-mediated lateral flow assay, Angew Chem Int Ed, 2021, 60, 5307−5315.
7. Meng Cheng, Erhu Xiong, Tian Tian, Debin Zhu, Huai-qiang Ju, Xiaoming Zhou, A CRISPR-driven colorimetric code platform for highly accurate telomerase activity assay, Biosensors and Bioelectronics 172 (2021) 112749.
8. Yijuan Bao, Yongzhong Jiang, Erhu Xiong, Tian Tian, Zhenzhen Zhang, Jing Lv, Yang Li*, Xiaoming Zhou*, CUT-LAMP: Contamination-Free Loop-Mediated Isothermal Amplification Based on CRISPR/Cas9 Cleavage, ACS Sensors, 2020, 5, 1082-1091.
9. Menglu Hu, Chaoqun Yuan, Tian Tian, Xusheng Wang, Jian Sun, Erhu Xiong*, Xiaoming Zhou*, Single-step, salt aging-free and thiol-free freezing construction of AuNP-based bioprobes for advancing CRISPR-based diagnostics, J. Am. Chem. Soc. 2020, 142, 7506−7513.
10. Jinjin Shen, Xiaoming Zhou, Yuanyue Shan, Huahua Yue, Ru Huang, Jiaming Hu*, and Da Xing*, Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction, Nature Communications, 2020, 11(1): 1-10.
11. Xusheng Wang, Erhu Xiong, Tian Tian, Meng Cheng, Wei Lin, Heng Wang, Guihong Zhang, Jian Sun*, and Xiaoming Zhou*, Clustered Regularly Interspaced Short Palindromic Repeats/Cas9-Mediated Lateral Flow Nucleic Acid Assay, ACS Nano, 2020, 14, 2497−2508.
12. Chaoqun Yuan#, Tian Tian#, Jian Sun, Menglu Hu, Xusheng Wang, Erhu Xiong, Meng Cheng, Yijuan Bao, Wei Lin, Jieming Jiang, Chengwei Yang, Qian Chen, Huang Zhang, Heng Wang, Xiran Wang, Xianbo Deng, Xiaoping Liao, Yahong Liu, Zhang Wang*, Guihong Zhang*, Xiaoming Zhou*, Universal and Naked-Eye Gene Detection Platform Based on CRISPR/Cas12a/13a System, Analytical Chemistry, 2020, 92, 4029−4037.
13. Qian Chen, Tian Tian, Erhu Xiong, Po Wang*, and Xiaoming Zhou*, CRISPR/Cas13a Signal Amplification Linked Immunosorbent Assay for Femtomolar Protein Detection, Analytical Chemistry, 2020, 92, 573-577.
14. Erhu Xiong, Deshuai Zhen, Ling Jiang*, and Xiaoming Zhou*, Binding-Induced 3D-Bipedal DNA Walker for Cascade Signal Amplification Detection of Thrombin Combined with Catalytic Hairpin Assembly Strategy, Analytical Chemistry, 2019, 91, 15317−15324.
15. Yuanyue Shan, Xiaoming Zhou, Ru Huang, and Da Xing*, High-Fidelity and Rapid Quantification of miRNA Combining crRNA Programmability and CRISPR/Cas13a trans-Cleavage Activity, Analytical Chemistry, 2019, 91, 5278−5285.
16. Chun Wu, Ke-Jia Wu, Jin-Biao Liu, Xiaoming Zhou, Chung-Hang Leung* and Dik-Lung Ma*, A dual-functional molecular strategy for in situ suppressing and visualizing of neuraminidase in aqueous solution using iridium(III) complexes, Chemical Communications, 2019, 55(45): 6353-6356.
17. Yuhui Liao, Xiaoming Zhou*, Yu Fu, and Da Xing*, Graphene Oxide as a Bifunctional Material Towards Superior RNA Protection and Extraction, ACS Appl. Mater. Interfaces, 2018, 10, 30227-30234.
18. Hongxing Liu, Xiaoming Zhou*, Qi Shen, and Da Xing*, Paper-based electrochemiluminescence sensor for highly sensitive detection amyloid oligomerization: Toward potential diagnosis of Alzheimer’s disease, Theranostics, 2018, 8, 2289-2299.
19. Huahua Yue, Xiaoming Zhou*, Da Xing*, Graphene oxide-mediated Cas9/sgRNA delivery for efficient genome editing, Nanoscale, 2018, 10, 1063-1071.
20. Mengqi Huang, Xiaoming Zhou*, Huiying Wang, and Da Xing*, Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Triggered Isothermal Amplification for Site-Specific Nucleic Acid Detection, Analytical Chemistry, 2018, 90, 2193-2200.
21. Bofan Li, Xiaoming Zhou*, Hongxing Liu, Huaping Deng, Ru Huang, Da Xing*, Simultaneous Detection of Antibiotic Resistance Genes on Paper-Based Chip Using [Ru(phen)2dppz]2+ Turn-on Fluorescence Probe, ACS Appl. Mater. Interfaces, 2018, 10, 4494-4501.
22. Yu Fu, Xiaoming Zhou* and Da Xing*, Integrated Paper-based Detection Chip with Nucleic Acid Extraction and Amplification for Automatic and Sensitive Pathogen Detection, Sensors & Actuators: B. Chemical, 2018, 261, 288-296.
23. Ru Huang, Xiaoming Zhou*, Chunsun Zhang, Da Xing*, High-specific microRNA detection based on dual-recycling cascadereaction and nicking endonuclease signal amplification, Sensors & Actuators: B. Chemical, 2018, 264, 169-176.
24. Meng Cheng, Xiaoming Zhou* and Da Xing*, Peptide cleavage induced assembly enables highly sensitive electrochemiluminescence detection of protease activity, Sensors & Actuators: B. Chemical, 2018, 262, 516-521.
25. Yu Fu, Xiaoming Zhou* and Da Xing*, Lab-on-capillary: a rapid, simple and quantitative genetic analysis platform integrating nucleic acid extraction, amplification and detection, Lab on a Chip, 2017, 17, 4334-4341.
26. Yuhui Liao, Xiaoming Zhou*, Yu Fu, and Da Xing*, Linear Ru(bpy)32+−Polymer as a Universal Probe for Sensitive Detection of Biomarkers with Controllable Electrochemiluminescence Signal-Amplifying Ratio, Analytical Chemistry, 2017, 89, 13016−13023.
27. Huaping Deng, Xiaoming Zhou*, Qianwen Liu, Bofan Li, Hongxing Liu, Ru Huang, and Da Xing*, Paperfluidic Chip Device for Small RNA Extraction, Amplification, and Multiplexed Analysis, ACS Appl. Mater. Interfaces, 2017, 9, 41151−41158.
28. Xiaoke Yang, Xiaoming Zhou*, Minjun Zhu, Da Xing*, Sensitive detection of Listeria monocytogenes based on highly efficient enrichment with vancomycin-conjugated brush-like magnetic nano-platforms, Biosensors and Bioelectronics, 2017, 91, 238-245.
29. Huaping Deng, Qianwen Liu, Xin Wang, Ru Huang, Hongxing Liu, Qiumei Lin, Xiaoming Zhou* and Da Xing*, Quantum Dots-Labeled Strip Biosensor for Rapidand Sensitive Detection of MicroRNA Based on Target-Recycled Nonenzymatic Amplification Strategy, Biosensors and Bioelectronics, 2017, 87, 931–940.
30. Ru Huang, Yuhui Liao, Xiaoming Zhou*, Yu Fu, Da Xing*, Multiplexed detection of microRNA biomarkers from tumor cells andtissues with a homogeneous nano-photon switch, Sensors & Actuators: B. Chemical, 2017, 247, 505–513.
31. Hongxing Liu, Xiaoming Zhou*, Jinjin Shen, and Da Xing*, Sensitive Detection of Hg2+ with Switchable Electrochemiluminescence Luminophore and Disposable Bipolar Electrode, ChemElectroChem, 2017, 4, 1681–1685.
32. Weipeng Liu, Minjun Zhu, Hongxing Liu, Jitao Wei, Xiaoming Zhou* and Da Xing*, Invading stacking primer: a trigger for high-efficiency isothermal amplification reaction with superior selectivity for detecting microRNA variants, Biosensors and Bioelectronics, 2016, 81, 309–316.
33. Lisha Zhang, Xiaoming Zhou* and Da Xing*, Rapid and Visual Detection of Listeria monocytogenes Based on Nanoparticle Cluster Catalyzed Signal Amplification, Biosensors and Bioelectronics, 2016, 86, 1-7.
34. Weipeng Liu, Huiheng Yu, Xiaoming Zhou* and Da Xing*, In Vitro Evaluation of CRISPR/Cas9 Function by an Electrochemiluminescent Assay, Analytical Chemistry, 2016, 88, 8369-8374.
35. Hongxing Liu, Xiaoming Zhou*, Weipeng Liu, Xiaoke Yang, and Da Xing*, Paper-Based Bipolar Electrode Electrochemiluminescence Switch for Label-Free and Sensitive Genetic Detection of Pathogenic Bacteria, Analytical Chemistry, 2016, 88, 10191-10197.
36. Qianwen Ding, Qiuqiang Zhan, Xiaoming Zhou, Tao Zhang* and Da Xing*, Theranostic Upconversion Nanobeacons for Tumor mRNA Ratiometric Fluorescence Detection and Imaging-Monitored Drug Delivery, Small, 2016, 12, 5944-5953.
37. Fang Liu, Hongxing Liu,Yuhui Liao,Jitao Wei, Xiaoming Zhou* and Da Xing*, Multiplex detection and genotyping of pathogenic bacteria on paper-based biosensor with a novel universal primer mediated asymmetric PCR, Biosensors and Bioelectronics, 2015,74, 778–785.
38. Minjun Zhu, Weipeng Liu, Hongxing Liu, Yuhui Liao, Jitao Wei, Xiaoming Zhou* and Da Xing* Construction of Fe3O4/Vancomycin/PEG Magnetic Nanocarrier for Highly Efficient Pathogen Enrichment and Gene Sensing, ACS Appl. Mater. Interfaces, 2015, 7, 12873−12881.
39. Yuhui Liao, Yu Fu, Yunxia Wu, Ru Huang, Xiaoming Zhou* and Da Xing*, Ultrasensitive Detection of MicroRNA in Tumor Cells and Tissues via Continuous Assembly of DNA Probe, Biomacromolecules, 2015, 16, 3543−3551.
40. Ru Huang, Yuhui Liao, Xiaoming Zhou*, Da Xing*, Toehold-mediated nonenzymatic amplification circuit on grapheme oxide fluorescence switching platform for sensitive and homogeneous microRNA detection, Analytica Chimica Acta, 2015, 888, 162-172.
41. Xiaoming Zhou, DebinZhu, Yuhui Liao, Weipeng Liu, Hongxing Liu, Zhaokui Ma, Da Xing*, Synthesis, labelling, and bioanalytical applications of a tris (2, 2'-bipyridyl) ruthenium (II) based electrochemiluminescence probe, Nature Protocols, 2014, 9, 1146-1159.
42. Ting Zhou, Xiaoming Zhou*, Da Xing*, Controlled release of doxorubicin from graphene oxide based charge-reversal nanocarrier, Biomaterials, 2014, 35, 4185-4194.
43. Yuhui Liao, Ru Huang, Zhaokui Ma, Yunxia Wu, Xiaoming Zhou*, and Da Xing*, A target-triggered enzyme-free amplification strategy for sensitive detection of microRNA in tumor cells and tissues, Analytical Chemistry, 2014, 86, 4596-4604.
44. Weipeng Liu, Xiaoming Zhou*, Da Xing*, Rapid and reliable microRNA detection by stacking hybridization on electrochemiluminescent chip system, Biosensors and Bioelectronics, 2014, 58, 388–394.
45. Hongxing Liu, Fangfang Zhan, Fang Liu,Minjun Zhu, Xiaoming Zhou* and Da Xing*, Visual and sensitive detection of viable pathogenic bacteria by sensing of RNA markers in gold nanoparticles based paper platform, Biosensors and Bioelectronics, 2014, 62, 38–46.
46. Yuhui Liao, Xiaoming Zhou* and Da Xing*, Quantum Dots and Graphene Oxide Fluorescent Switch Based Multivariate Testing Strategy for Reliable Detection of Listeria monocytogenes, ACS Appl. Mater. Interfaces, 2014, 6, 9988−9996.
47. Jitao Wei, Hongxing Liu, Fang Liu, Minjun Zhu, Xiaoming Zhou*, Da Xing* Miniaturized Paper-Based Gene Sensor for Rapid and Sensitive Identification of Contagious Plant Virus, ACS Appl. Mater. Interfaces, 2014, 6, 22577−22584.
48. Jianzhi Liu; Yongjun Hu*; Guichi Zhu; Xiaoming Zhou; Li Jia; Tao Zhang, Highly Sensitive Detection of Zearalenone in Feed Samples Using Competitive Surface-Enhanced Raman Scattering Immunoassay, Journal of Agricultural and Food Chemistry, 2014, 62, 8325-8332.
49. Yi Long, Xiaoming Zhou*, Da Xing*, An isothermal and sensitive nucleic acids assay by target sequence recycled rolling circle amplification, Biosensors and Bioelectronics, 2013, 46, 102-107.
50. Zhongyu Fu, Xiaoming Zhou*, Da Xing*, Sensitive colorimetric detection of Listeria monocytogenes based on isothermal gene amplification and unmodified gold nanoparticles, Methods, 2013,64, 260–266.
51. Zhongyu Fu, Xiaoming Zhou*, Da Xing*, Rapid colorimetric gene-sensing of food pathogenic bacteria using biomodification-free gold nanoparticle, Sensors & Actuators: B. Chemical, 2013,182, 633–641.
52. Xiao Zhu, Xiaoming Zhou, Da Xing*, Label-Free Detection of MicroRNA: Two-Step Signal Enhancement with a Hairpin-Probe-Based Graphene Fluorescence Switch and Isothermal Amplification, Chemistry A European Journal, 2013, 19, 5487–5494.
53. Fangfang Zhan, Xiaoming Zhou, Da Xing*, Rapid and sensitive electrochemiluminescence detection of rotavirus by magnetic primer based reverse transcription-polymerase chain reaction, Analytica Chimica Acta, 2013, 761, 71-77.
54. Xiaoming Zhou, Yuhui Liao, Da Xing*, Sensitive monitoring of RNA transcription levels using a graphene oxide fluorescence switch, Chinese Science Bulletin, 2013, 21: 2634-2639.
55. Xiaoming Zhou, and Da Xing*, Assays for human telomerase activity: progress and prospects, Chemical Society Reviews, 2012, 41, 4643-4656.
56. Liyun Xue, Xiaoming Zhou (co-first author), and Da Xing*, Sensitive and Homogeneous Protein Detection Based on Target- Triggered Aptamer Hairpin Switch and Nicking Enzyme Assisted Fluorescence Signal Amplification, Analytical Chemistry, 2012, 84, 3507−3513.
57. Xiaoming Zhou, Qiang Su, Da Xing*, An electrochemiluminescent assay for high sensitive detection of mercury based on isothermal rolling circular amplification, Analytica Chimica Acta, 2012, 713, 45–49.
58. Xiaoming Zhou, Ruixue Duan, and Da Xing*, Highly sensitive detection of protein and small molecules based on aptamer-modified electrochemiluminescence nanoprobe, Analyst, 2012, 137, 1963-1969.
59. Xiaoming Zhou, Da Xing*, Amplified electrochemiluminescence detection of nucleic acids by hairpin probe based isothermal amplification, Analyst, 2012, 137, 4188-4192.
60. Zhen Zhao, Xiaoming Zhou*, Ultrasensitive electrochemiluminescence detection of mercury ions based on DNA oligonucleotides and cysteamine modified gold nanoparticles probes, Sensors & Actuators: B. Chemical, 2012 (171–172) 860– 865.
61. Zhen Zhao, Xiaoming Zhou, Da Xing*, Highly sensitive protein kinase activity assay based on electrochemiluminescence nanoprobes, Biosensors and Bioelectronics, 2012, 31, 299-304.
62. Xiao Zhu, Xiaoming Zhou, Da Xing*, Nano-magnetic primer based electrochemiluminescence-polymerase chain reaction (NMPE-PCR) assay, Biosensors and Bioelectronics, 2012, 31, 463-468.
63. Xiaoming Zhou, Yonghong Tang, and Da Xing*, One-Step Homogeneous Protein Detection Based on Aptamer Probe and Fluorescence Cross-Correlation Spectroscopy, Analytical Chemistry, 2011, 83, 2906–2912.
64. Yi Long, Xiaoming Zhou, Da Xing*, Sensitive and isothermal electrochemiluminescence gene-sensing of Listeria monocytogenes with hyperbranching rolling circle amplification technology, Biosensors and Bioelectronics, 2011, 26, 2897-2904.
65. Xiao Zhu, Xiaoming Zhou, Da Xing*, Ultrasensitive and Selective Detection of Mercury (II) in Aqueous Solution by Polymerase Assisted Fluorescence Amplification, Biosensors and Bioelectronics, 2011, 26, 2666-2669.
66. Ruixue Duan, Xiaoming Zhou (co-first author), Da Xing*, Electrochemiluminescence Biobarcode Method Based on Cysteamine-Gold Nanoparticle Conjugates, Analytical Chemistry, 2010, 82, 3099-3103.
67. Jie Wei, Xiaoming Zhou (co-first author), Da Xing*, Rapid and sensitive detection of vibrio parahaemolyticus in sea foods by electrochemiluminescence polymerase chain reaction method, Food Chemistry, 2010, 123, 852-858.
68. Liyun Xue, Xiaoming Zhou and Da Xing*, Highly sensitive protein detection based on aptamer probe and isothermal nicking enzyme assisted fluorescence signal amplification, Chemical Communications, 2010, 46, 7373–7375.
69. Qiang Li, Xiaoming Zhou, Da Xing*, Rapid and highly sensitive detection of mercury ion (Hg2+) by magnetic beads-based electrochemiluminescence assay, Biosensors and Bioelectronics, 2010, 26, 859-862.
70. Qiang Su, Da Xing*, Xiaoming Zhou, Magnetic beads based rolling circle amplification–electrochemiluminescence assay for highly sensitive detection of point mutation, Biosensors and Bioelectronics, 2010, 25, 1615-1621.
71. Debin Zhu, Xiaoming Zhou, Da Xing*, A new kind of aptamer-based immunomagnetic electrochemiluminescence assay for quantitative detection of protein, Biosensors and Bioelectronics, 2010, 26, 285-288.
72. Xiaoming Zhou, Da Xing*, Debin Zhu, Li Jia, Magnetic bead and nanoparticle based electrochemiluminescence amplification assay for direct and sensitive measuring of telomerase activity, Analytical Chemistry, 2009, 81, 255-261.
73. Xiaoming Zhou, Da Xing*, Yonghong Tang, and Wei R. Chen, PCR-Free Detection of Genetically Modified Organisms Using Magnetic Capture Technology and Fluorescence Cross-Correlation Spectroscopy, PLoS One, 2009, 4, e8074.
74. Huijuan Zhou, Da Xing*, Debin Zhu, and Xiaoming Zhou, Rapid and sensitive detection of point mutation by DNA ligase-based electrochemiluminescence assay, Talanta, 2009, 78, 1253-1258.
75. Xiaoming Zhou, Da Xing*, Debin Zhu and Li Jia, Magnetic beads-based electrochemiluminescence assay for rapid and sensitive detection of telomerase activity, Electrochemistry Communications, 2008, 10, 564-567.
76. Xiaoming Zhou, Da Xing*, Debin Zhu, Yabing Tang, and Li Jia, Development and application of a capillary electrophoresis- electrochemiluminescent method for the analysis of enrofloxacin and its metabolite ciprofloxacin in milk, Talanta, 2008, 75, 1300–1306.
77. Jie Wei, Xiaoming Zhou*, An improved electrochemiluminescence polymerase chain reaction method for the detection of Fusarium wilts, Chinese Chemical Letters, 2008, 19, 959–961.
