吳森(中國農業大學生物學院生物化學與分子生物學系教授)

吳森，男，博士。

現任中國農業大學生物學院生物化學與分子生物學系教授。

基本介紹

• 中文名：吳森
• 畢業院校：美國 University of Utah
• 學位/學歷：博士
• 專業方向：動物遺傳工程及幹細胞
• 任職院校：中國農業大學

人物經歷

1988—1993 北京農業大學動物醫學院本科

1993—1998 衛生部北京生物製品研究所助理工程師；加拿大University of Saskatchewan碩士研究生

1999—2006 美國University of Utah博士學位（導師Mario Capecchi）；美國HHMI/University of Utah博士後（導師Mario Capecchi）

2010—至今 中國農業大學生物學院教授

主講課程

《動物高級生理學與分子生物學》

發表論文

1. Kurokawa S, Eriksson S, Rose KL, Wu S, Motley AK, Hill S, Winfrey VP, McDonald WH, Capecchi MR, Atkins JF, Arnér ES, Hill KE, Burk RF. Sepp1(UF) forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1. Free Radic Biol Med. 69C:67-76. 2014
2. Hill KE, Wu S, Motley AK, Stevenson TD, Winfrey VP, Capecchi MR, Atkins JF, Burk RF. Production of selenoprotein P (Sepp1) by hepatocytes is central to selenium homeostasis. J Biol Chem. 287(48):40414-24. 2012
3. Hill KE, Wu S, Motley AK, Stevenson TD, Winfrey VP, Capecchi MR, Atkins JF, Burk RF.Production of selenoprotein P (Sepp1) by hepatocytes is central to selenium homeostasis.J Biol Chem. 2012 Nov 23;287(48):40414-24. doi: 10.1074/jbc.M112.421404. Epub 2012 Oct 4.PMID: 23038251
4. Chen SK, Tvrdik P, Peden E, Cho S, Wu S, Spangrude G, Capecchi MR.Hematopoietic origin of pathological grooming in Hoxb8 mutant mice. Cell. 2010May 28;141(5):775-85. PubMed PMID: 20510925; PubMed Central PMCID: PMC2894573.
5. Xue H, Wu S, Papadeas ST, Spusta S, Swistowska AM, MacArthur CC, Mattson MP,Maragakis NJ, Capecchi MR, Rao MS, Zeng X, Liu Y. A targeted neuroglial reporterline generated by homologous recombination in human embryonic stem cells. StemCells. 2009 Aug;27(8):1836-46. PubMed PMID: 19544414; PubMed Central PMCID:PMC2741170.
6. Ying G, Wu S, Hou R, Huang W, Capecchi MR, Wu Q. The protocadherin gene Celsr3is required for interneuron migration in the mouse forebrain. Mol Cell Biol. 2009Jun;29(11):3045-61. Epub 2009 Mar 30. PubMed PMID: 19332558; PubMed CentralPMCID: PMC2682005.
7. Jia Q, McDill BW, Sankarapandian B, Wu S, Liapis H, Holzman LB, Capecchi MR,Miner JH, Chen F. Ablation of developing podocytes disrupts cellular interactionsand nephrogenesis both inside and outside the glomerulus. Am J Physiol RenalPhysiol. 2008 Dec;295(6):F1790-8. Epub 2008 Oct 8. PubMed PMID: 18842818; PubMed Central PMCID: PMC2604822.
8. Wu S, Ying G, Wu Q, Capecchi MR. A protocol for constructing gene targetingvectors: generating knockout mice for the cadherin family and beyond. Nat Protoc.2008;3(6):1056-76. PubMed PMID: 18546598.
9. Wu S, Ying G, Wu Q, Capecchi MR. Toward simpler and faster genome-widemutagenesis in mice. Nat Genet. 2007 Jul;39(7):922-30. Epub 2007 Jun 17. PubMedPMID: 17572674.
10. Wu S, Wu Y, Capecchi MR. Motoneurons and oligodendrocytes are sequentiallygenerated from neural stem cells but do not appear to share commonlineage-restricted progenitors in vivo. Development. 2006 Feb;133(4):581-90. Epub2006 Jan 11. PubMed PMID: 16407399.
11. Gaufo GO, Wu S, Capecchi MR. Contribution of Hox genes to the diversity of thehindbrain sensory system. Development. 2004 Mar;131(6):1259-66. Epub 2004 Feb 11.PubMed PMID: 14960494.