吳川六，男，畢業於廈門大學，博士，廈門大學化學化工學院教師。
基本介紹
- 中文名：吳川六
- 學位/學歷：博士
- 職業：教師
- 專業方向：多肽分子探針；螢光探針；多肽/蛋白遞送系統等
- 任職院校：廈門大學
個人經歷,研究興趣,學術成果,
個人經歷
博士（廈門大學，2005-2010）
學士（廈門大學，2001-2005）
研究助理（新加坡國立大學，2008-2009）
博士後（瑞士蘇黎世聯邦理工學院，2010-2012）
ETH Fellow（2010）
研究興趣
多肽分子探針；螢光探針；多肽/蛋白遞送系統；蛋白質–多肽分子相互作用；生物分子識別機制
學術成果
1. Yunyang Ling,‡ Jing Ren,‡ Tao Li, Yibing Zhao and Chuanliu Wu*, POEGMA-Based Disulfide-Containing Fluorescent Probes for Imitating and Tracing Noninternalization-Based Intracellular Drug Delivery, Chem. Commun., 2016, 52, 4533−4536.
2. Yiwu Zheng, Linxiang Zhai, Yibing Zhao, and Chuanliu Wu*, Orthogonal Cysteine-Penicillamine Disulfide Pairing for Directing the Oxidative Folding of Peptides, J. Am. Chem. Soc., 2015, 137, 15094−15097.
3. Yujie Li,‡ Tao Li,‡ Jinghui Wang, Xiaojia Bao, Yibing Zhao, and Chuanliu Wu*, Multivalent Peptides Displayed on OEGMA-based Copolymers for the Modulation of Protein-Protein Interactions, Polym. Chem., 2015, 6, 7862−7870.
4. Yaqi Chen,‡ Chaoqiong Yang,‡ Tao Li, Miao Zhang, Yang Liu, Marc A. Gauthier, Yibing Zhao, and Chuanliu Wu*, The Interplay of Disulfide Bonds, α-Helicity, and Hydrophobic Interactions Leads to Ultrahigh Proteolytic Stability of Peptides, Biomacromolecules, 2015, 16, 2347−2355.
5. Linxiang Zhai, Jingjing Liang, Xiangqun Guo, Yibing Zhao, and Chuanliu Wu*, Extraordinary Modulation of Disulfide Redox-Responsiveness by Cooperativity of Twin-Disulfide Bonds, Chem. Eur. J., 2014, 20, 17507−17514.
6. Chuanliu Wu,‡ Shuo Wang,‡ Lorine Brülisauer, Jean-Christophe Leroux, and Marc A. Gauthier*, Broad Control of Disulfide Stability through Microenvironmental Effects and Analysis in Complex Redox Environments, Biomacromolecules, 2013, 14, 2383−2388.
7. Chuanliu Wu, Jean-Christophe Leroux,* and Marc A. Gauthier*, Twin Disulfides for Orthogonal Disulfide Pairing and the Directed Folding of Multicyclic Peptides, Nature Chem., 2012, 4, 1044−1049.
8. Chuanliu Wu, Cristina Belenda, Jean-Christophe Leroux, and Marc A. Gauthier*, Interplay of Chemical Microenvironment and Redox Environment on Thiol–Disulfide Exchange Kinetics, Chem. Eur. J., 2011, 17, 10064−10070.
