吳少華(雲南大學生命科學學院研究員)

吳少華,女,博士,雲南大學生命科學學院研究員。

基本介紹

  • 中文名:吳少華
  • 國籍:中國
  • 畢業院校:中科院昆明植物研究所
  • 學位/學歷:博士
  • 專業方向:微生物學
人物經歷,研究方向,教授課程,主要論文,

人物經歷

1992.9-1996.7,中山大學化學系,套用化學專業,獲學士學位;
1996. 9-2001. 12,中科院昆明植物研究所碩博連讀,獲博士學位;
2002. 1-2004. 11,雲南大學生命科學學院微生物研究所,助理研究員;
2002. 8-2003. 2,德國耶拿Hans-Knöll天然產物研究所,訪問學者
2004. 12-2010. 11,雲南大學生命科學學院微生物研究所,副研究員
2010. 12-至今,雲南大學生命科學學院微生物研究所,研究員

研究方向

主要從事微生物學和天然產物化學研究。重點開展以下三個方面的研究:
1、植物內生菌資源及生物活性的研究:植物內生菌是微生物資源研究的熱點之一,在農業和醫藥領域具有廣闊的套用前景。從特色藥用植物中分離和鑑定內生菌,進行內生菌資源的多樣性研究,開展抗腫瘤、抗病毒、抗菌等多種生物活性篩選,發現有醫用和農用潛力的活性菌株。
2、微生物活性天然產物的研究:綜合運用微生物學、天然產物化學、藥理學等多學科專業技術,開展不同生境來源的真菌和放線菌中活性次生代謝產物的分離、結構鑑定以及生理活性篩選,發現結構新穎的具有重要生理活性的化合物,致力於微生物天然藥物的研究與開發。
3、植物內生菌與宿主之間關係密切,從內生菌的種群結構和次生代謝的角度探討內生菌與宿主植物的相互作用。

教授課程

碩士生專業必修課《微生物資源與代謝產物化學》

主要論文

  1. Shou-Peng Zhang, Rong Huang, Fang-Fang Li, Hong-Xia Wei, Xiao-Wei Fang, Xiao-Song Xie, Dong-Guo Lin, Shao-Hua Wu*, Jian He*. Antiviral anthraquinones and azaphilones produced by an endophytic fungus Nigrospora sp. from Aconitum carmichaeli. Fitoterapia, 2016, 112, 85-89.
  2. Xiao-Song Xie, Xiao-Wei Fang, Rong Huang, Shou-Peng Zhang, Hong-Xia Wei, Shao-Hua Wu*. A new dimericanthraquinone from endophytic Talaromyces sp. YE3016. Natural Product Research, 2016, 30(15), 1706-1711.
  3. Rong Huang, Tang Wang, Xiao-Song Xie, Kai-Xia Ma, Xiao-Wei Fang, Shao-Hua Wu*. Secondary metabolites from an endophytic fungus Nigrospora sp. Chemistry of Natural Compounds, 2016, 52(4), 697-699.
  4. Huang Rong, Xie Xiao-Song, Xiao-Wei Fang, Ma Kai-Xia, Wu Shao-Hua*. Five new guaiane sesquiterpenes from the endophytic fungus Xylaria sp. YM 311647 of Azadirachta indica. Chemistry & Biodiversity, 2015, 12(8), 1281-1286.
  5. Huang Rong, Ma Kai-Xia, Xie Xiao-Song, Wang Tang, Wu Shao-Hua*. Secondary metabolites of an endophytic fungus Phomopsis sp., Chemistry of Natural Compounds, 2015, 51(2), 392-394.
  6. Wu Shao-Hua*, He Jian, Li Xiao-Nian, Huang Rong, Song Fei, Chen You-Wei, Miao Cui-Ping. Guaiane sesquiterpenes and isopimarane diterpenes from an endophytic fungus Xylaria sp. Phytochemistry, 2014, 105, 197-204.
  7. Song Fei, Wu Shao-Hua*, Zhai Ying-Zhe, Xuan Qi-Cun, Wang Tang. Secondary metabolites from the genus Xylaria and their bioactivities. Chemistry & Biodiversity, 2014, 11(5), 673- 694.
  8. Wang Tang, Jiang Yi, Ma Kai-Xia, Xie Xiao-Song, Wu Shao-Hua*. Two new butenolides produced by an actinomycete Streptomyces sp. Chemistry & Biodiversity, 2014, 11(6), 929-933.
  9. Ma Kai-Xia, Shen Xin-Tian, Huang Rong, Wang Tang, Xie Xiao-Song, Liu Shu-Wen, Wu Shao-Hua*, He Jian. Bioactive metabolites produced by the endophytic fungus Phomopsis sp. Natural Product Communications, 2014, 9(5), 669-670.
  10. Xuan Qi-Cun, Huang Rong, Chen You-Wei, Miao Cui-Ping, Ma Kai-Xia, Wang Tang, Wu Shao-Hua*. Cyclonerol derivatives from Trichoderma longibrachiatum YM311505. Natural Product Communications, 2014, 9(3), 313-314.
  11. Xuan Qi-Cun, Huang Rong, Miao Cui-Ping, Chen You-Wei, Zhai Ying-Zhe, Song Fei, Wang Tang, Wu Shao-Hua*. Secondary metabolites of endophytic fungus Trichoderma sp. YM 311505 of Azadirachta indica. Chemistry of Natural Compounds, 2014, 50(1), 139-141.
  12. Wu Shao-Hua*, Huang Rong, Miao Cui-Ping, Chen You-Wei. Two new steroids from an endophytic fungus Phomopsis sp. Chemistry & Biodiversity, 2013, 10(7), 1276-1283.
  13. Wu Shao-Hua*, Zhao Li-Xing, Chen You-Wei, Huang Rong, Miao Cui-Ping, Wang Jiao. Sesquiterpenoids from the endophytic fungus Trichoderma sp. PR-35 of Paeonia delavayi. Chemistry & Biodiversity, 2011, 8(9), 1717-1723.
  14. Wu Shao-Hua*, Chen You-Wei, Miao Cui-Ping. Secondary metabolites of endophytic fungus Xylaria sp. YC-10 of Azadirachta indica. Chemistry of Natural Compounds, 2011, 47(5), 858-861.
  15. Wu Shao-Hua*, Wu Da-Gang, Chen You-Wei. Chemical constituents and bioactivities of plants from the genus Paeonia. Chemistry & Biodiversity, 2010, 7(1), 90-104.
  16. Wu Shao-Hua*, Chen You-Wei, Shao Shi-Cheng, Wang Li-Dong, Yu Ying, Li Zhi-Ying, Yang Li-Yuan, Li Shao-Lan, Huang Rong. Two new solanapyrone analogues from the endophytic fungus Nigrospora sp. YB-141 of Azadirachta indica. Chemistry & Biodiversity, 2009, 6(1), 79-85.
  17. Wu Shao-Hua*, Chen You-Wei, Li Zhi-Ying, Yang Li-Yuan, Li Shao-Lan. Chemical constituents from the root bark of Paeonia delavayi. Chemistry of Natural Compounds, 2009, 45(4), 597-598.
  18. Wu Shao-Hua*, Shen Yue-Mao, Chen You-Wei, Li Zhi-Ying, Yang Li-Yuan, Li Shao-Lan. Chemical constituents from the stem bark of Trewia nudiflora. Chemistry of Natural Compounds, 2009, 45(4), 536-538.
  19. Wu Shao-Hua*, Chen You-Wei, Shao Shi-Cheng, Wang Li-Dong, Li Zhi-Ying, Yang Li-Yuan, Li Shao-Lan, Huang Rong. Ten-membered lactones from Phomopsis sp., an endophytic fungus of Azadirachta indica. Journal of Natural Products, 2008, 71(4), 731-734.
  20. Wu Shao-Hua, Chen You-Wei, Qin Sheng, Huang Rong. A new spiroketal from Aspergillus terreus, an endophytic fungus in Opuntia ficusindica Mill. Journal of Basic Microbiology, 2008, 48(2), 140-142.
  21. Wu Shao-Hua*, Chen You-Wei, Yang Li-Yuan, Li Shao-Lan, Li Zhi-Ying. A new ellagic acid glycoside from Paeonia delavayi. Fitoterapia, 2008, 79(6), 474-475.

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