劉靂宇,男,1980年出生,重慶大學物理學院教授,博士生導師。
國家級青年人才、國家“973”青年項目首席科學家、國家級人才聯誼會副秘書長、重慶市青年領軍人才協會副理事長、重慶市歐美同學會副會長、重慶市政協常委。
基本介紹
- 中文名:劉靂宇
- 出生地:成都
- 出生日期:1980年
- 畢業院校:香港科技大學
- 學位/學歷:博士
- 專業方向:癌症生物物理等
人物經歷,研究方向,人物貢獻,所獲榮譽,學術成果,
人物經歷
1980年生於成都。2004年畢業於中國科學技術大學力學與機械工程系,獲學士學位;2008年獲香港科技大學納米科學與納米技術博士學位。2012年加入中國科學院物理研究所“百人計畫”,任特聘研究員,博士生導師。2015年加入重慶大學物理學院,任教授。
政協重慶市第六屆委員會委員、常務委員
研究方向
1. 癌症生物物理:基於改變腫瘤微環境的癌症治療新方法探索;
2. 微流控類器官晶片的研究與套用;
3. 自組織機器人集群,自組織集群行為湧現機理研究。
人物貢獻
劉靂宇團隊在國際上首次發現取向性的人體微環境能夠極大增強癌細胞轉移時侵襲血管的能力、首次實驗觀測到了癌細胞侵襲的博弈行為等,在國際學術圈產生一定影響。
所獲榮譽
中國科學院“盧嘉錫”人才獎
東京工業大學青年科學家獎
重慶市十佳科技青年獎
重慶市物理學科帶頭人
學術成果
基金項目:
1. 科技部“973計畫”青年科學家專題(2013CB837200)
“三維微納米生物晶片在肝癌和大腸癌肝轉移中的分子機理研究及其臨床套用”
2. 自然科學基金面上項目(11604030)
“功能性彈性血管的動力學及在重大疾病研究中的套用”
3. 自然科學基金面上項目(11474345)
“3-D生物晶片中癌細胞侵襲組織的集體行為和動力學研究“
4. 北京市自然科學基金(7154221)
“數字影像分析結合3-D列印技術探索心血管FFR的體外無創診斷”
5. 自然科學基金面上項目(11974066)
“介觀尺度下癌細胞侵襲取向性膠原纖維的動力學研究”
代表性論文:
21. "The Impact of Hybrid Compositional Film/Structure on Organic-Inorganic Perovskite Solar Cells", Y. Wu, W. Chen, G. Chen,L. Liu, Z. He, R. Liu,Nanomaterials8 (6) doi: 10.3390/nano8060356 (2018)
20. "Realizations of highly heterogeneous collagen networks via stochastic reconstruction for micromechanical analysis of tumor cell invasion", H. Nan, L. Liang, G. Chen,L. Liu, R. Liu, Y. Jiao,Physical Review E97 (3) 033311 (2018)
19. "Microfabrication-Based Three-Dimensional (3-D) Extracellular Matrix Microenvironments for Cancer and Other Diseases", K. Song, Z. Wang, R. Liu, G. Chen,L. Liu, InternationalJournal of Molecular Science19 (4) doi:10.3390/ijms19040935 (2018)
18. "SKPM study on organic-inorganic perovskite materials", K. Song, Y. Wu, X. Chen, Y. He,L. Liu, G. Chen, R. Liu,AIP Advances8 (3) 0351114 (2018)
17. Y. Liu, X. Zhang, Y. Wu, W. Liu, X. Li, R. Liu,L. Liu, J. Shuai, "Derivation of persistent time for anisotropic migration of cells",Chin. Phys. BVol. 26, No. 12 (2017) 128707 (2017)
16. Q. Fan, R. Liu, Y. Jiao, C. Tian, James D. Farrell, X. Wang, F. Zhang, W. Yuan, H. Han, J. Chen, Y Yang, X. Zhang, F. Ye, M. Li, Z. Ouyang, andL. Liu, "A novel 3-D bio-microfluidic system mimicking in vivo heterogeneous tumour microstructure reveals complex tumourstroma interactions",Lab on a ChipDOI:10.1039/C7LC00191F(2017)
15. W. Han, S. Chen, W.Yuan, Q. Fan, J. Tian, X. Wang, L. Chen, X. Zhang, W. Wei, R. Liu, Junle Qu, Y. Jiao, Robert H.Austin, andL. Liu, "Oriented collagen fibers direct tumor cell intravasation",Proc. Natl. Acad. Sci. USA(2016)
14. R. Liu, Y.Li, andL. Liu, "Single molecule fluorescence spectroscopy for quantitative biological applications",Quantitative Biology177–191 (2016)
13. G. Wang , X. Wang , T. Liu , R. Liu , andL. Liu, "In vitro experimental models and their molding technology of tumor cell",Acta. Phys. Sin.65,188700 (2016)
12. H. Wang, J. Liu, X. Zheng, X. Rong, X. Zheng, H. Peng, Z. S. Li, M. Li,L. Liu, "Three-dimensional virtual surgery models for percutaneous coronary intervention (PCI) optimization strategies",Sci. Rep.5,10945 (2015)
11. J. Zhu, L. Liang, Y. Jiao,L. Liu, "Enhanced Invasion of Metastatic Cancer Cells via Extracellular Matrix Interface",PLoS ONE10,1371 (2015)
10.L. Liu, G. Duclos, B. Sun, J. Lee, A. Wu, Y. Kam, E. D. Sontag, H. A. Stone, J. C. Sturm, R. A. Gatenby and R. H. Austin, "Minimization of thermodynamic costs in cancer cell invasion",Proc. Natl. Acad. Sci. USA10.1073 (2013)
9.L. Liu, B. Sun, K. Aw Yong, R. Getzenberg, H. Stone and R. Austin, “Probing the invasiveness of prostate cancer cells in a 3D microfabricated landscape”,Proc. Natl. Acad. Sci. USA108:6853–6856 (2011)(高亮文章)
8.L. Liu, K. Loutherback, D. Liao, D. Yeater, G. Lambert, A. Estevez-Torres, J. Sturm, R. Getzenberg and R. Austin, “A microfluidic device for continuous cancer cell culture and passage with hydrodynamic forces”,Lab on a Chip10, 1807-1813 (2010)
7.L. Liu, W. Cao, J. Wu, W. Wen, D. C. Chang and P. Sheng, “Design and Integration of an All-in-One Biomicrofluidic Chip”,Biomicrofluidics2,034103 (2008)
6.L. Liu, S. Peng, W. Wen and P. Sheng, “Micro Thermo Indicators and Optical-Electronic Temperature Control for Microfluidic Applications”,Appl. Phys. Lett. 91, 093513 (2007)
5.L. Liu, S. Peng, W. Wen and P. Sheng, “ Paperlike thermochromic display”,Appl. Phys. Lett.90 213508 (2007)
4.L. Liu, S. Peng, X. Niu and W. Wen, “Microheater fabricated from a conducting composite”,Appl. Phys. Lett.89, 223521 (2006)
3.L. Liu, X. Niu, W. Wen and P. Sheng, “Electrorheological fluid-actuated flexible platform”,Appl. Phys. Lett.88, 173505 (2006)
2.L. Liu, X. Chen, X. Niu, W. Wen, and P. Sheng, “Electrorheological fluid actuated microfluidic pump”,Appl. Phys. Lett.89, 083505 (2006)
- L. Liu, X. Huang, C. Shen, Z. Liu, J. Shi, W. Wen and P. Sheng, “Parallel-field electrorheological clutch: Enhanced high shear rate performance”,Appl. Phys. Lett.87, 104106 (2005)