修志龍

修志龍，男，畢業於大連理工大學，博士，大連理工大學教授、博士生導師、碩士生導師。

基本介紹

• 中文名：修志龍
• 畢業院校：大連理工大學
• 學位/學歷：博士
• 專業方向：生物化工
• 任職院校：大連理工大學

人物經歷

教育經歷

1979.9-1982.8 山東省海陽一中

1998.9-2000.7 大連理工大學生物化工博士

1987.9-1990.7 大連理工大學生物化工碩士

1982.9-1987.7 清華大學化學工程學士

工作經歷

2010.3至今 大連理工大學生命科學與技術學院教授

2002.10-2010.3 大連理工大學環境與生命學院教授

1997.10-2002.10 大連理工大學化工學院副教授

1992.12-1997.10 大連理工大學化工學院講師

1990.3-1992.12 大連理工大學化工學院助教

學術成果

論文成果

[1]Pan, Duo-Tao,Wang, Xu-Dong,Shi, Hong-Yan,Yuan, De-Cheng,Xiu, Zhi-Long.Ensemble optimization of microbial conversion of glycerol into 1, 3-propanediol by Klebsiella pneumoniae[J],JOURNAL OF BIOTECHNOLOGY,2019,301:68-78

[2]Dong, Yue-Sheng,Yang, Fan,Liu, Wen-Cai,Wang, Xu-Dong,Xing, Yan,Xiu, Zhi-Long.Separation and purification of wortmannilactone analogues by three-liquid-phase salting-out extraction coupled with column chromatography[J],SEPARATION AND PURIFICATION TECHNOLOGY,2019,224:397-404

[3]Li, Zhen,Yan, Ling,Zhou, Jinjie,Wang, Xiaoli,Sun, Yaqin,Xiu, Zhi-Long.Two-step salting-out extraction of 1,3-propanediol, butyric acid and acetic acid from fermentation broths[J],SEPARATION AND PURIFICATION TECHNOLOGY,2019,209:246-253

[4]Yuan Yuyu,Qu Kunli,Tan Demeng,Li Xiaoyu,Wang Lili,Cong Cong,Xiu Zhilong,Xu Yongping.Isolation and characterization of a bacteriophage and its potential to disrupt multi-drug resistant Pseudomonas aeruginosa biofilms[J],Microbial pathogenesis,2019,128:329-336

[5]Dai Jianying,Wang Zhuangfei,Xiu Zhi-Long.High production of optically pure (3R)-acetoin by a newly isolated marine strain of Bacillus subtilis CGMCC 13141[J],Bioprocess and biosystems engineering,2019,42(3):475-483

[6]Pan, Duo-Tao,Wang, Xu-Dong,Shi, Hong-Yan,Yuan, De-Cheng,Xiu, Zhi-Long.Dynamic flux balance analysis for microbial conversion of glycerol into 1,3-propanediol by Klebsiella pneumoniae[J],BIOPROCESS AND BIOSYSTEMS ENGINEERING,2018,41(12):1793-1805

[7]Wang, Xu-Dong,Wei, Ning-Ning,Wang, Shu-Chang,Yuan, Heng-Li,Zhang, Feng-Ying,Xiu, Zhi-Long.Kinetic Optimization and Scale-Up of Site-Specific Thiol-PEGylation of Loxenatide from Laboratory to Pilot Scale[J],INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,2018,57(44):14915-14925

[8]Sun, Yaqin,Zhang, Shuangshuang,Zhang, Xingxing,Zheng, Yafeng,Xiu, Zhilong.Ionic liquid-based sugaring-out and salting-out extraction of succinic acid[J],SEPARATION AND PURIFICATION TECHNOLOGY,2018,204:133-140

[9]Zhou, Jin-Jie,Shen, Jun-Tao,Wang, Xiao-Li,Sun, Ya-Qin,Xiu, Zhi-Long.Stability and oscillatory behavior of microbial consortium in continuous conversion of crude glycerol to 1,3-propanediol[J],APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2018,102(19):8291-8305

[10]Dou, Shaohua,Chi, Naiyu,Zhou, Xinshang,Zhang, Qingfang,Pang, Fei,Xiu, Zhilong.Molecular cloning, expression, and biochemical characterization of a novel cold-active alpha-amylase from Bacillus sp dsh19-1[J],EXTREMOPHILES,2018,22(5):739-749

[11]Wang, Xudong,Wang, Shuchang,Pan, Duotao,Qin, Kairong,Yuan, Hengli,Zhang, Fengying,Sun, Yundong,Xiu, Zhilong.Combined optimization of N-terminal site-specific PEGylation of recombinant hirudin using response surface methodology and kinetic analysis[J],ENGINEERING IN LIFE SCIENCES,2018,18(8):611-621

[12]Dai, Jianying,Wang, Hui,Li, Yan,Xiu, Zhi-Long.Imidazolium ionic liquids-based salting-out extraction of 2,3-butanediol from fermentation broths[J],PROCESS BIOCHEMISTRY,2018,71:175-181

[13]Sun, Ya-Qin,Shen, Jun-Tao,Yan, Ling,Zhou, Jin-Jie,Jiang, Li-Li,Chen, Yang,Yuan, Jin-Long,Feng, Enmin,Xiu, Zhi-Long.Advances in bioconversion of glycerol to 1,3-propanediol: Prospects and challenges[J],PROCESS BIOCHEMISTRY,2018,71:134-146

[14]Zhang, Bowei,Xiu, Zhilong,Ma, Baiping,Yu, Liyan,Dong, Yuesheng,Sun, Wenlong,Yu, Na,Sun, Jin,Yu, Xiaoxia,Li, Xia,Xing, Yan,Yan, Dong,Ding, Qianzhi.Anti-diabetic effect of baicalein is associated with the modulation of gut microbiota in streptozotocin and high-fat-diet induced diabetic rats[J],JOURNAL OF FUNCTIONAL FOODS,2018,46:256-267

[15]Yan, Ling,Sun, Ya-Qin,Wang, Xu-Dong,Fu, Hong-Xin,Mu, Ying,Xiu, Zhi-Long.Partition behavior of monocarboxylic acids in salting-out extraction systems of monohydric alcohols and dipotassium phosphate[J],SEPARATION AND PURIFICATION TECHNOLOGY,2018,199:351-358

[16]孜力汗,賈凌雲,楊君,修志龍,包永明,袁文杰,牟英,唐穎.通過科研與教學的結合建設生物工程專業校內實習實訓基地[J],化工高等教育,2018,35(3):75-81

[17]胡春燕,王旭東,秦超,董悅生,修志龍.克拉維酸鉀一步結晶工藝最佳化[J],高校化學工程學報,2018,32(4):910-917

[18]Dong, Zhenyu,Tan, Bing,Zhang, Yuduo,Yuan, Jinlong,Feng, Enmin,Yin, Hongchao,Xiu, Zhilong.Strong stability of an optimal control hybrid system in fed-batch fermentation[J],INTERNATIONAL JOURNAL OF BIOMATHEMATICS,2018,11(4)

[19]Zhao Shan,Yang Fan,Liu Yang,Sun Dongsheng,Xiu Zhilong,Ma Xiaojun,Zhang Ying,Sun Guangwei.Study of chemical characteristics, gelation properties and biological application of calcium pectate prepared using apple or citrus pectin.[J],International journal of biological macromolecules,2018,109:180-187

[20]Xing, Yan,Chen, Chaonan,Sun, Wenlong,Zhang, Bowei,Sang, Yuanbin,Xiu, Zhilong,Dong, Yuesheng.An environment-friendly approach to isolate and purify glucan from spent cells of recombinant Pichia pastoris and the bioactivity characterization of the purified glucan[J],ENGINEERING IN LIFE SCIENCES,2018,18(4):227-235

專利成果

一種具有協同作用的α-糖苷酶抑制劑組合物及其套用

一種基於生長耦聯的底物流加發酵生產1,3-丙二醇的方法

一種微生物轉化法製備屬於皂素的方法

一種改善高脂高糖飲食併發症的藥物組合物及其套用

一種矽酸鹽催化製備生物柴油的方法

一種從克雷伯氏桿菌發酵液中提取1，3-丙二醇的方法

著作成果

代謝工程的途徑分析與最佳化

生物化學

成功的科研寫作

生物工程與技術導論

多級生物加工系統最佳化原理與技術，第五章 1, 3-丙二醇生物合成過程及其最佳化與控制

Bioprocessing of renewable resources to commodity bioproducts

科研項目

基於生長和代謝特徵的底物流加發酵生產1,3-丙二醇的控制方法, 國家自然科學基金項目, 2018/07/20-2030/03/31, 進行

微生物發酵甘油年產一萬噸1,3-丙二醇, 企事業單位委託科技項目, 2018/06/29-2019/12/31, 進行

抗生素廢酸水處理技術, 企事業單位委託科技項目, 2016/12/30-2018/06/30, 進行

海洋微生物菌群的特性及其工業套用, 其他課題, 2016/11/28, 進行

三種青黴素醯化酶的鹽析萃取技術, 自選課題, 2016/07/08-2016/12/30, 進行

聚乙二醇洛塞那肽工藝最佳化及作用機制研究, 自選課題, 2016/07/09-2017/07/19, 完成