侯可勇，男，博士，山東大學教授。
基本介紹
- 中文名：侯可勇
- 學位/學歷：博士
- 職業：教師
- 專業方向：線上軟電離源質譜研製及其在環境污染物現場應急檢測中的套用
- 任職院校：山東大學
個人經歷,研究方向,學術成果,
個人經歷
教育背景：
2002.9-2008.1， 中國科學院大連化學物理研究所，分析化學，博士
1998.7-2002.7，青島大學，化學，學士
工作經歷：
2019.11-至今，山東大學環境研究院，教授
2016.6-2019.11，中科院大連化學物理研究所，研究員
2013.1-2016.12，中科院青年促進會會員
2011.10-2016.6，中科院大連化學物理研究所，副研究員
2009.10-2011.4，Purdue University，R. Graham Cooks課題組，博後
2008.1-2009.10，中科院大連化學物理研究所，助理研究員
研究方向
1.線上軟電離源質譜研製及其在環境污染物現場應急檢測中的套用；
2.大氣壓化學電離質譜研製及其在大氣成核關鍵物種探測研究；
3.離子高效傳輸技術、高分辨及高精度飛行時間質譜分析器研究；
4.質譜微型化技術及其在國家安全分析套用研究。
學術成果
科研項目：
1.國家重大儀器專項課題，“微分遷移譜-飛行時間質譜模組”編號：2013YQ09070302，2013.10-2016.12
2.國家重大研究計畫子課題“易製毒化學品現場鑑定便攜熱解析質譜技術及套用研究”，編號2016YFC0800902,2016.7-2019.6.30
3.863資環領域子課題，“低成本高通量環境分析質譜”，編號：2014AA06A501，2014.1.1-2017.12.30
4.國家自然科學基金面上項目，“面聲波電離攜帶型離子阱質譜路檢唾液鑑定毒駕研究”，編號：21874134，2018.1-2021.12
5.國家自然科學基金面上“離子富集式無窗VUV光電離源及其在攜帶型TOFMS現場檢測VOCs中的套用”，編號：21675155，2017.1-2020.12
6.國家自然科學基金面上項目，“可快速切換VUV電離和射頻增強的化學電離源及其在C2-C12碳氫化合物線上質譜測量中的套用”，編號：21375129，2014.1-2017.12
7.國家自然科學基金青年基金，水中痕量甲基叔丁基醚（MTBE）及其降解產物的線上質譜檢測新方法研究，編號：20907052，2010.1-2012.12
8.中科院儀器研製項目，“工業VOCs減排技術快速評價裝置”，編號:KZCX2-YW-JS402，2010.1-2013.12
9.遼寧省自然科學優秀人才培育基金，“還原性硫化物線上檢測光電子電離遷移譜”，負責人，編號：2014020089，2014.1-2016.12
10.大連市重點基金，“六氟化硫絕緣全封閉組合電器電氣故障線上診斷儀器”，編號：2015A11GX031,2016.1.1-2017.12.30
11.遼寧省博士啟動基金，高靈敏線上質譜水中污染物監測技術,編號：Y034090102，2009.1-2010.12
參與的科研項目：
1.國家支撐項目課題，“離子阱質譜的毒品現場查緝和快速鑑定技術與設備的研究”，編號：2013BAK14B04，2013.1-2015.12
2.國家重大儀器專項課題，“超高分辨飛行時間分析器”編號：2011YQ05006904，2011.1-2018.12
發表的主要論文：
1.Chuting,Xu, Weiming,Wang, Shuang Wang，Keyong Hou*，Haiyang Li*, Potential analytical methods for on-site oral drug test: Recent developments and applications,TrAC, 2019, 115649
2.Weiming,Wang, Shuang Wang，Chuting Xu，Hong Li，Yuming Xing，
Keyong Hou*，Haiyang Li*, Rapid Screening of Trace Volatile and Nonvolatile Illegal Drugs by Miniature Ion Trap Mass Spectrometry: Synchronized Flash-Thermal-Desorption Purging and Ion Injection，Anal. Chem.2019,91,10212-10220
3.Shuang Wang, Weimin Wang,Hong Li, Yuming Xing,Keyong Hou,*and Haiyang Li*,Rapid On-Site Detection of Illegal Drugs in Complex Matrix by
Thermal Desorption Acetone-Assisted Photoionization Miniature Ion Trap Mass Spectrometer,Anal. Chem., 2019,91,3845-3852
4.Chenxin Wu, Wei Liu,Jichun Jiang, Yan Wang,Keyong Hou*,and Haiyang Li*,An in-source helical membrane inlet single photon ioni-zation time of flight mass spectrometer for automatic monitoring of trace VOCs in water at minutes resolution，Talanta，2019，42,46-51
5.Yan Wang, Lei Hua, Qingyun Li, Jichun Jiang,Keyong Hou, Chenxin Wu, and Haiyang Li *，Direct Detection of Small n-Alkanes at Sub-ppbv Level by Photoelectron-Induced O2Cation Chemical Ionization Mass Spectrometry at kPa Pressure，Anal. Chem., 2018, 90 (8), pp 5398–5404
6.Yan Wang, Lei hua, Jichun Jiang, Yuanyuan Xie,Keyong Hou, Qingyun Li, Chenxin Wu and Haiyang Li *, High-pressure photon ionization time-of-flight mass spectrometry combined with dynamic purge-injection for rapid analysis of volatile metabolites in urine.Analytica Chimica Acta.1008 (2018) 74-81
7.Zhou Lijuan, Jiang Jichun, Zhao Kun, Li Jinxu, Wu Chenxin, Li Haiyang, Tian Di*,Hou Keyong*, “Radiofrequency field enhanced chemical ionization with vacuum ultraviolet lamp for miniature time-of-flight mass spectrometer”.Chinese Chem. Lett., 2018. Volume 29, Issue 5, 707-710
8.Hou Keyong, Li J, Qu T, Tang B, Zhu LP, Huang YG, Li HY*. “Development of a suitcase time-of-flight mass spectrometer for in situ fault diagnosis of SF6‐insulated switchgear by detection of decomposition products”.Rapid Commun. Mass Spectrom., 2016, 30(S1): 38-43.
9.Liu W, Jiang J,Hou Keyong, Weiguo Wang, Yachen Qi, Yan Wang, Yuanyuan Xie, Lei Hua, Haiyang Li *. “Online monitoring of trace chlorinated benzenes in flue gas of municipal solid waste incinerator by windowless VUV lamp single photon ionization TOFMS coupled with automatic enrichment system”.Talanta, 2016, 161: 693-699.
10.Wang Yan, Jiang Jichun, Hua Lei,Keyong Hou, Yuanyuan Xie, Ping Chen, Wei Liu, Qingyun Li, Shuang Wang, and Haiyang Li*, “High-Pressure Photon Ionization Source for TOFMS and Its Application for Online Breath Analysis”.Anal. Chem., 2016, 88(18): 9047-9055.
11.Jichun Jiang, Yan Wang,Keyong Hou, Lei Hua, Ping Chen, Wei Liu , Yuanyuan Xie, Haiyang Li*, “Photoionization-Generated Dibromomethane Cation Chemical Ionization Source for Time-of-Flight Mass Spectrometry and Its Application on Sensitive Detection of Volatile Sulfur Compounds.Anal. Chem.2016, 88, 5028–5032
12.Yuanyuan Xie, Ping Chen, Lei Hua,Keyong Hou, Yongchao Wang, Haiyan Wang, Haiyang Li*, “Rapid Identification and Quantification of Linear Olefin Isomers by Online Ozonolysis-Single Photon Ionization Time-of-Flight Mass Spectrometry”,J.Am. Soc. Mass Spectrom., 2016, 27(1): 144-152.
13.Wendong Chen,Keyong Hou,Lei Hua, Haiyang Li*, “Dopant-assisted reactive low temperature plasma probe for sensitive and specific detection of explosives”,Analyst, 2015, 140(17): 6025-6030
14.Lei Hua,Keyong Hou,Ping Chen, Yuanyuan Xie, Jichun Jiang, Yan Wang, Weiguo Wang, and Haiyang Li* , “Realization of In-Source Collision-Induced Dissociation in Single-Photon Ionization Time-of-Flight Mass Spectrometry and Its Application for Differentiation of Isobaric Compounds”,Anal. Chem.,2015,87(4), pp 2427–2433
15.Chuang Chen,Keyong Hou,Weiguo Wang, Jinghua Li,Haiyang Li*, “Ambienttemperature nanoelectrospray ion mobility detector for high performance liquid chromatography in determining amines”, J. Chromatogr. A. 2014; 1358, 192-198.
16.Yuanyuan Xie, Lei Hua,Keyong Hou, Ping Chen, Wuduo Zhao, Wendong Chen, Bangyu Ju, and Haiyang Li*, “Long-Term Real-Time Monitoring Catalytic Synthesis of Ammonia in a Microreactor by VUV-Lamp-Based Charge-Transfer Ionization Time-of-Flight Mass Spectrometry”, Anal. Chem., 2014, 86 (15), pp 7681–7687
17.Wendong Chen,Keyong Hou,Lei Hua, Xingchuang Xiong, Haiyang Li*, “Water-assisted low temperature plasma ionization source for sensitive detection of explosives” ,RSC Advances, 2014 , 28,4, 14791-14794,
18.Ping Chen,Keyong Hou, Lei Hua, Yuanyuan Xie, Wuduo Zhao, Wendong Chen, Chuang Chen, and Haiyang Li*，“Quasi-Trapping Chemical Ionization Source Based on a Commercial VUV Lamp for Time-of-Flight Mass Spectrometry”,Anal. Chem., 2014, 86 (3), pp 1332–1336
19.Shasha Cheng, Weiguo Wang, Qinghua Zhou, Chuang Chen, Liying Peng, Lei Hua, Yang Li,Keyong Hou, and Haiyang Li*, “Fast Switching of CO3–(H2O)n and O2–(H2O)n Reactant Ions in Dopant-Assisted Negative Photoionization Ion Mobility Spectrometry for Explosives Detection”，Anal. Chem., 2014, 86,2687-2693
20.Keyong Hou,Fanglong Li, Wendong Chen, Ping Chen, Yuanyuan Xie , Wuduo Zhao , Lei Hua , Kemei Pei, Haiyang Li* ,“An In-Source Stretched Membrane Inlet for On-Line Analysis of VOCs in Water with Single Photon Ionization TOFMS”,Analyst, 2013,138(17):5826-5831
21.Chen W,Hou Keyong*, Xiong X, Jiang Y, Zhao W, Hua L, Chen P, Xie Y, Wang Z, Li H*. “Non-contact halogen lamp heating assisted LTP ionization miniature rectilinear ion trap: a platform for rapid, on-site explosives analysis”.Analyst, 2013,138(17):5068-73.
22.Shasha Cheng, Jian Dou, Weiguo Wang, Chuang Chen, Lei Hua, Qinghua Zhou,Keyong Hou, Jinghua Li, and Haiyang Li*. “Dopant-Assisted Negative Photoionization IMS for Sensitive Detection of Explosives”,Anal. Chem.,2013, 85, 319−326
23.Xixi Liang, Qinghua Zhou, Weiguo Wang, Xin Wang, Wendong Chen, Chuang Chen,Yang Li,Keyong Hou, Jinghua Li, and Haiyang Li*, “Sensitive Detection of Black Powder by a Stand-Alone Ion Mobility Spectrometer with an Embedded Titration Region”,Anal. Chem.,2013, 85, 4849−4852
24.Qinghao Wu, Lei Hua,Keyong Hou, Huapeng Cui, Haiyang Li*, “Vacuum Ultraviolet Lamp Based Magnetic Field Enhanced Photoelectron Ionization and Single Photon Ionization Source for Online Time-of-Flight Mass Spectrometry”,Anal. Chem., 2011 , Vol 83, 8992-8998
25.Keyong Hou, Wei Xu, R. Graham Cooks*, Zheng Ouyang*, “Sampling Wand for an Ion Trap Mass Spectrometer”,Anal. Chem., 2011, Vol 83 (5), 1857-1861
26.Lei Hua, Qinghao Wu,Keyong Hou*, Huapeng Cui, Ping Chen, Weiguo Wang, Jinghua Li, Haiyang Li*, “Single Photon Ionization and Chemical Ionization Combined Ion Source Based on a Vacuum Ultraviolet Lamp for Orthogonal Acceleration Time-of-Flight Mass Spectrometry”,Anal. Chem.2011，83(13):5309-5316
27.Chuang Chen, Can Dong, Yongzhai Du, Shasha Cheng, Fenglei Han, Lin Li, Weiguo Wang,Keyong Hou, Haiyang Li*, “Bipolar Ionization Source for Ion Mobility Spectrometry Based on Vacuum Ultraviolet Radiation Induced Photoemission and Photoionization”，Anal. Chem.，2010, Vol 82,4151-4157
授權的主要專利：
1.侯可勇，董璨，李海洋，“飛行時間質譜儀中真空紫外燈電離裝置”，發明專利，專利申請號：200610011793.2，2009.4.29授權
2.侯可勇，李海洋，“一種線上氣體分析質譜中的膜進樣樣品富集裝置”，發明專利，專利申請號：200710011223.8，2011.12.14授權
3.侯可勇，李海洋，“微型飛行時間質譜線上樣品富集裝置”，發明專利，專利申請號：200610134947.7，2011.08.31授權
4.侯可勇，花磊，吳慶浩，崔華鵬，李海洋， “微型質譜儀中空心陰極放電真空紫外光電離源”，發明專利，專利申請號：200910265445.1，2012.11.07授權
5.侯可勇，陳文東，李海洋，一種添加選擇性檢測試劑的介質阻擋放電質譜電離源裝置，發明專利，201210536370.8，2015.12.09授權
6.侯可勇，陳文東，崔華鵬，花磊，一種肩背式便攜線上分析飛行時間質譜儀，發明專利：201110233344.3，2015.12.02授權
7.侯可勇，趙無垛，陳文東，李海洋，一種直線加速型飛行時間質譜中光電離源，發明專利，201210562884.0，2016.03.16授權
8.侯可勇，崔華鵬，花磊，陳平，李海洋，“一種高靈敏線上分析爆炸物的質譜電離源及其套用”，發明專利：201110233372.5，2016.03.16授權
9.侯可勇，李芳龍，陳文東，李海洋，一種線上質譜電離源內管狀膜進樣裝置，發明專利：201210234534.1，2016.06.15授權
10.侯可勇，花磊，陳平，崔華鵬，李海洋，一種大面積原位檢測爆炸物的質譜電離源及其套用，發明專利：201110232457.1，2015.12.16授權
11.侯可勇，李芳龍，陳文東，李海洋，一種用於線上質譜的直熱式管狀膜富集進樣裝置，發明專利：201210234821.2，2016.12.21授權
12.侯可勇，蘇明揚，李海洋，陳平，蔣吉春，李金旭，一種電離源內螺旋管狀膜進樣裝置，發明專利：201310694028.5，2017.1.25授權
國內外學術口頭報告：
2015.5.8在武漢召開“中國化學會第十二屆全國分析化學年會”報告：線上分析水中VOCs的光電離源內螺旋膜進樣質譜方法研究。
2015.7.26西班牙科爾多瓦，"24th International Conference on Ion Mobility Spectrometry"報告："Identification of the characteristic ions of 2-CEES in negative mode by 63Ni ionization source IMS-TOFMS "。
2015.9.11，北京，現場檢測儀器前沿技術研討會，邀請報告：爆炸物現場檢測技術研究。
2015.10.16，在杭州召開“中國化學會第二屆全國質譜分析學術報告會”報告：真空紫外光電離源的進展和套用。
2016.8.20,加拿大多倫多, “21st International Mass Spectrometry Conference”，報告：VUV lamp based chemical ionization source for on-situ ion trap mass spectrometry。
2017.6.3 ,美國印第安納波利斯, 65American Society for Mass Spectrometry年會,報告：Development of an Ultrahigh Resolution Multi-reflection Time-of-Flight Mass Spectrometer for Native Mass Spectrometry。
2017.11.8 ,廈門,第三屆全國質譜分析會議，報告：基於真空紫外燈的化學電離微型飛行時間質譜及其套用。
2018年6月，西安會議，中國分析化學會第十三屆全國分析化學年會，報告：軟電離線上質譜快速分析大氣中揮發性有機物。
2018.11.3，青島，第24屆中國大氣環境科學與技術大會，報告：汽車中8種VOCs快速線上檢測研究。
2018年11月24，廣州，中國質譜大會，報告：攜帶型離子阱質譜及其在毒品現場檢測中套用研究。
2019年6月1號，67 th American Society for Mass Spectrometry年會，報告：Pulse-sampling assisted flash heating desorption miniature ITMS with photoionization for sensitivity and on-site identification of illegal drugs。
