Xue X, Xiao Y, Gong LK, Guan SH, Liu YZ, Lu HL, Qi XM, Zhang YH, Li Y, Wu XF and Ren J. Comparative 28-day repeated oral toxicity of Longdan Xieganwan, Akebia trifoliate koidz, Akebia quinata (Thunb.) Decne and Caulis aristolochiae manshuriensis in mice. Journal of Ethnopharmacology
Xue X, Xiao Y, Zhu HL, Wang H, Liu YZ, Xie TP, Ren J. Induction of P450 1A by 3-methylcholanthrene protects mice from aristolochic acid-I-induced acute renal injury. Nephrology Dialysis Transplantation
Zhang YH, Qi XM , Gong LK, Li Y, Liu LL, Xue X, Xiao Y, Wu XF, Ren J. Roles of reactive oxygen species and MAP Kinases in the primary rat hepatocytes death induced by toosendanin. Toxicology
Xiao Y, Ge M, Xue X, Wang C, Wang H, Wu X, Li L, Liu L, Qi X, Zhang Y, Li Y, Luo H, Xie T, Gu J and Ren J. Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity. Kidney Internationa
Wang ZH, Shen B, Yao HL, Jia YC, Ren J, Feng YJ. Blockage of intermediate-conductance-Ca (2+) -activated K(+) channels inhibits progression of human endometrial cancer. Oncogene
Liu LL, Gong LK, Wang H, Xiao Y, Wu XF, Zhang YH, Xue X, Qi XM, Ren J. Baicalin inhibits macrophage activation by lipopolysaccharide and protects mice from endotoxin shock. Biochemical Pharmacology
Liu LL, Gong LK, Wang H, Xiao Y, Wu XF, Zhang YH, Xiang X, Qi XM, Ren J. Baicalin protects mouse from Concanavalin A-induced liver injury through inhibition of cytokine production and hepatocyte apoptosis. Liver Internationa
Qi XM, Cai Y, Gong LK, Liu LL, Chen FP, Xiao Y, Wu XF, Li Yan, Xue X, Ren J. Role of mitochondrial permeabilitytran sition in human renal tubular epithelial cell death induced by aristolochic acid. Toxicology and Applied Pharmacology,
Qi XM, Yu B, Huang XC, Guo YW, Zhai Q and Ren J. The cytotoxicity of lingshuiol, a comparative study with amphidinol 2 on membrane permeabilizing activities. Toxicon
Chen FP, Gong LK and Ren J. Early lung injury contribute to lung fibrosis via AT1 receptor in rats. Acta Pharmacologica Sinica
Chen FP, Gong LK, Zhang L, Zhang YH, Qi XM, Wu XF, Xiao Y, Cai Y, Liu LL, Wang H, Liu YZ, Li XH, Ren J. Short courses of low dose dexamethasone delay bleomycin-induced lung fibrosis in rats. European Journal of Pharmacology
Ma D, Jiang Y, Chen F, Gong LK, Ding K, Xu Y, Wang R, Ge A, Ren J, Li J, Ye Q. Selective inhibition of matrix metalloproteinase isozymes and in vivo protection against emphysema by substituted gamma-keto carboxylic acids. Journal of Medicinal Chemistry
Cai Y, Qi XM, Gong LK, Liu LL, Chen FP, Xiao Y, Wu XF, Li XH, Ren J. Tetrandrine-induced apoptosis in rat primary hepatocytes is initiated from mitochondria: Caspases and Endonuclease G (Endo G) pathway. Toxicology
Fujita T, Utsunomiya I, Ren J, Matsushita Y, Kawai M, Sasaki S, Hoshi K, Miyatake T Taguchi K. Glycosylation and cell surface expression of Kv1.2 potassium channel are regulated by determinants in the pore region. Neurochemical Research
Cai Y, Gong LK, Qi XM, Li XH, Ren J. Apoptosis initiatedby carbon AAIrachloride in mitochondria of rat primary cultured hepatocytes. Acta Pharmacologica Sinica
Liu LL, Gong LK, Qi XM, Cai Y, Wang H, Wu XF, Xiao Y, Ren J. Altered expression of cytochrome P450 and possible correlation with preneoplastic changes in the early stage of rat hepatocarcinogenesis. Acta Pharmacologica Sinica
Gong LK, Li XH, Wang H, Zhang L, Chen FP, Cai Y, Qi XM, Liu LL, Liu YZ, Wu XF, Huang CG, Ren J. Effect of Feitai on pulmonary fibrosis in rats. Journal of Ethnopharmacology
Li XH,Ren J. Establishment of a GLP Compliance Program for Drug Safety Studies at SIMM. Quality Assurance Journal
Gong LK, Li XH, Wang H, Zhang L, Cai Y, Qi XM, Liu LL, Liu YZ, Wu XF, Chen FP, Huang CG, Ren J. Feitai attenuates bleomycin-induced pulmonary fibrosis in rats. Biological & Pharmaceutical Bulletin
Ren J, Cai Y, Gong LK, Qi XM, Liu LL, and Li XH. Mitochondria-initiated apoptosis in primary cultured rat hepatocytes by carbon tetrachloride (Abstr). Toxicology and Applied Pharmacology
Liu LL, Qi XM, Gong LK, Cai Y, Ren J. Expression of microsomal cytochrome p450 (cyps) in medium-term bioassay for rat hepatocarcinogenesis (Abstr). Toxicology and Applied Pharmacology
Gong LK, Cai Y, Qi XM, Liu LL, Li XH, Ren J. The effect of carbon tetrachloride on hepatocytes: cytotoxicity and related mechanisms in rat primary cultured hepatocytes (Abstr). Toxicology