是TIGR維護的物種特異的基因和EST（表達序列標籤）資料庫，其中TIGR是The Institute for Genomic Research的縮寫。目前該資料庫已包含動物、植物、原生生物、真菌四大類87個物種的基因索引，每年數據升級三次。
基本介紹
- 中文名：TIGR Gene Indices
- 外文名：The Institute for Genomic Research
- 橋樑：基因組數據，聯繫直系同源
- 維護：TIGR維護的物種特異的基因
簡介,發展,
簡介
TIGR Gene Idices，TIGR基因索引是TIGR維護的物種特異的基因和EST（表達序列標籤）資料庫，其中TIGR是The Institute for Genomic Research的縮寫。
發展
目前該資料庫已包含動物、植物、原生生物、真菌四大類87個物種的基因索引，每年數據升級三次。網站界面很友好，點擊首頁的某個物種圖示就可以進入相應物種的基因索引。IGR Gene Idices收錄的基因數據不是簡單的對GenBank的基因和EST數據按物種分類，而是從GenBank中提取不同物種的EST和注釋的基因序列，通過聚類、拼接等分析過程(TIGR Assembler (Sutton et al. 1995,Genome Science and Technology 1: 9-19))，產生唯一的(unique)、高可信度的虛擬轉錄本或者是假設性一致序列(Tentative Consensus sequences)，這種假設性一致序列便可用來提供假定基因數據，可以成為聯繫轉錄本與基因作圖、基因組數據，聯繫直系同源和旁系同源基因的橋樑。
English Summary
Database DescriptionExpressed Sequence Tags (ESTs) have provided a first glimpse of the collection of transcribed sequences in a variety of organisms. However, a careful analysis of this sequence data can provide significant additional functional, structural, and evolutionary information. Our analysis of the public EST sequences, available through the TIGR Gene Indices (TGI; http://www.tigr.org/tdb/tdb.html), is an attempt to identify the genes represented by that data and to provide additional information regarding those genes. Gene Indices are constructed for selected organisms by first clustering, then assembling EST and annotated gene sequences from GenBank. This process produces a set of unique, high-fidelity virtual transcripts, or Tentative Consensus (TC) sequences. The TC sequences can be used to provide putative genes with functional annotation, to link the transcripts to mapping and genomic sequence data, and to provide links between orthologous and paralogous genes.
